Overcome Male Infertility - The Hypoosmotic swelling test (HOST)

Posted by Chantel Martiromo

Fertility is a natural process to insure the survival of human species. Through natural selection, we produce many offspring when the reproductive system works at it's peak in the suitable environment with plenty of food around. On the other hand, the reproductive system may completely shut down or work at it's minimum state and we produce less offspring, when the environment is hostile including less foods around, war, epidemic, but regardless of all these factors, most women are capable of conceiving during their menstrual cycle before menopause.

Hypoosmotic swelling test (HOST) is the test used to identify sperm membrane for structure integrity by examining how the sperm tail reacts to special sugar and salt. Only healthy sperm can react in this circumstance.

I. Procedure
The HOS test was performed by mixing special sugar and salt in distilled water. The mixture was incubated and immediately examined under a microscope. The percentage of reacted sperm (curled tails) and non-reacted sperm (non-curled tails) were assessed.

II. Diagnosis
1. A sample sperm is considered normal if more than 60% response to the swollen spermatozoa. otherwise the tested sample is considered to have poor sperm membrane structure integrity. It is said the hypoosmotic swelling test result is predictive of the sperm penetration test. If the tested sample fail, it may need some other technical support to by-pass the sperm penetration process.

III. Risk
Although the hypoosmotic swelling test is less time consuming and can help to determine the the sperm fertilization capacity, the result is not 100% guaranteed. For the couple to conceive, it take more than the hypoosmotic swelling test for a successful pregnancy, please make sure that other health problems have been taking care of.

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