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Monday, July 9, 2012

Novel soy protein wound dressings with controlled antibiotic release

 Posted by Chantel M. Contributed by US National Library of Medicine National Institutes of Health

In the observation of Novel soy protein wound dressings with controlled antibiotic release: mechanical and physical properties, posted in PubMed, researchers suggested that the gentamicin release profile exhibited a moderate burst effect followed by a decreasing release rate which was maintained for at least 4 weeks. Diffusion was the dominant release mechanism of gentamicin from cross-linked SPI films. Appropriate selection of the process parameters yielded SPI wound dressings with the desired mechanical and physical properties and drug release behavior to protect against bacterial infection. These unique structures are thus potentially useful as burn and ulcer dressings.

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