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Monday, August 11, 2014

Grape and Asthma

Posted by Chantel Martiromo

Respiratory Disease is defined as medical conditions which affect the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and  muscles breathing , etc.
 Asthma is a chronic inflammatory disease affecting the air way of the lung with recurring symptoms, such as wheezing, chest tightness, shortness of breath, and coughing. The disease affects people of all ages, and mostly starts during childhood. According to American academy, allergy, asthma and immunology, about 1 in 10 children (10%) had asthma and 1 in 12 adults (8%) had asthma in 2009. (about 25 million, or 8% of the U.S. population).

Grape is a woody vines of the genus Vitis, belong to the family Vitaceae, native to southern Turkey.
Polyphenols found in Fermented Grape Marc (FGM) may be effective in exhibited several immunomodulating activities, including decreased oxidative burst of human polymorphonuclear cells and monocytes of which induced anti-allergic and anti inflammatory effects in chronic asthma(22). According to the study of Graduate School of Science, Kitasato University, Fermented Grape Marc (FGM) also suppressed both phases of type-I allergic responses, through a fraction extractable with acetone(23).

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References
(22) Immunomodulating and Anti-Allergic Effects of Negroamaro and Koshu Vitis vinifera Fermented Grape Marc (FGM) by Marzulli G, Magrone T, Vonghia L, Kaneko M, Takimoto H, Kumazawa Y, Jirillo E(PubMed)
(23) Suppression of type-I allergic responses by oral administration of grape marc fermented with Lactobacillus plantarum by Tominaga T1, Kawaguchi K, Kanesaka M, Kawauchi H, Jirillo E, Kumazawa Y.(PubMed)

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