tag:blogger.com,1999:blog-44223784339447370362024-03-13T07:57:17.229-07:00Women HealthUnknownnoreply@blogger.comBlogger4544125tag:blogger.com,1999:blog-4422378433944737036.post-58378547788949709252023-08-27T07:42:00.004-07:002023-08-27T07:42:52.868-07:00#LowCaffeine #GreenTea Intake Daily and Regularly Reduces Stress and Improvef Sleep Quality, Scientists Say<br /><br /> Scientists may have found a beverage with the potential to improve stress and sleep quality, some studies suggested.<br /><br />According to the report published in Sleep Health. sleep quality is classified depending on the criteria of the person's sleep pattern, including<br />* Sleeping more time while in bed (at least 85 percent of the total time)<br />*Falling asleep in 30 minutes or less<br />*Waking up no more than once per night; and<br />* Being awake for 20 minutes or less after initially falling asleep<br />Sleep disturbances are encompassed disorders classified by the initiating and maintaining sleep (DIMS, insomnias), disorders of excessive somnolence (DOES), disorders of sleep-wake schedule, and dysfunctions associated with sleep, sleep stages, or partial arousals (parasomnias), the<br />Clinical Methods: The History, Physical, and Laboratory Examinations. 3rd edition wrote.<br /><br /><br />According to the statistic, over 50 million Americans, or 1 in 2,5 adults suffer from a sleep disorder and acute and chronic insomnia affects at least 30% and 10% of Americans, respectively.<br /><br />Although researchers do not why people with the same health conditions, carrying the same tasks, are susceptible to sleep disorders, while others do not, they do know that certain risk factors such as gender, age, people with emotional and psychological problems, frequent travelers, shift-worker, long-term under emotional stress are associated with the early onset of the condition,<br /><br />Green tea, a precious drink processes a number of health benefits known to almost everyone in Asia and the Western world.<br />In the concerns of injection of green tea and the risk of stress and sleep quality, researchers at the University of Shizuoka, launched an investigation to determine the effect of green tea with lowered caffeine, and low-caffeine green tea, on stress and sleep of the elderly.<br /><br />In the 10 subjects included in the study, participants drank five cups/day of standard green tea for 1 week. Subsequently, they drank five cups/day of low-caffeine green tea for 2 weeks.<br /><br />After measuring the salivary α-amylase activity (sAA) and sleep stages were measured using portable electroencephalography (n = 7, 6 female and 1 male), researchers found that<br />* The level of sAA in the morning (sAAm) was significantly lower when the participants drank low-caffeine green tea than standard green tea.<br /><br />* In those participants whose sAAm was lowered by the ingestion of low-caffeine green tea, some sleep parameters improved.<br /><br />* These results suggested that daily ingestion of low-caffeine green tea may be a beneficial tool for improving the quality of sleep of the elderly via the suppression of stress.<br /><br />Where salivary alpha-amylase levels are correlated to sleep-disordered breathing<br /><br />Furthermore, in the differentiation of the effect of low-caffeine green tea consumption on the risk of sleep quality on middle-aged individuals (n = 20, mean age 51.3 ± 6.7 years) in a double-blind crossover design, with standard green tea (SGT) used as the control and low caffeine green tea teas (≥300 mL/day), which were eluted with room temperature water, were consumed over a period of seven days after a single washout term, researchers indicated that<br />* The level of salivary α-amylase activity (sAA), a stress marker, was significantly lower in participants that consumed LCGT (64.7 U/mL) than in those that consumed SGT (73.9 U/mL).<br />* Sleep quality was higher in participants that consumed a larger quantity of LCGT.<br />* In addition, a self-diagnostic check for accumulated fatigue was significantly lower in those participants that consumed LCGT than SGT.<br />Dr. Unno K, the lead author of the final report said, " LCGT intake can reduce stress in middle-aged individuals and improve their quality of sleep. The reduction in caffeine is suggested to be a valid reason for enhancing the anti-stress effect of green tea".<br /><br />Taken together, it is safe to suggest that moderate consumption of low-caffeine green tea may have a profound effect in improving sleep quality by reducing the levels of stress.<br /><br /><br /><a href="http://9f55846cqkvfueo9njz33azt0t.hop.clickbank.net/?tid=KYLENORTON">Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight</a><br /><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">How To Get Rid Of Eye Floaters<br /></a><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Contrary To Professional Prediction, Floaters </a>C<a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">an Be </a><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Cured Naturally<br /></a><br />Ovarian Cysts And PCOS Elimination<br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Holistic System In Existence That Will Show You How To</a><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Permanently Eliminate All Types of Ovarian Cysts Within 2 Months</a><br /><br />Back to Kyle J. Norton's Homepage <a href="http://kylejnorton.blogspot.ca/">http://kylejnorton.blogspot.c</a>a<br /><br />Author Biography<br />Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)<br />Health article writer and researcher; Over 10,000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.<br />Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post<br />Nominated for shorty award over last 4 years<br />Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.<br />Sources<br />(1) Ingestion of green tea with lowered caffeine improves sleep quality of the elderly via suppression of stress by Unno K1,2, Noda S3, Kawasaki Y3, Yamada H3, Morita A4, Iguchi K1, Nakamura Y2. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/29203963">PubMed</a>)<br />(2) Reduced Stress and Improved Sleep Quality Caused by Green Tea Are Associated with a Reduced Caffeine Content by Unno K1,2, Noda S3, Kawasaki Y4, Yamada H5, Morita A6, Iguchi K7,<br />Nakamura Y8(<a href="https://www.ncbi.nlm.nih.gov/pubmed/28753943">PubMed</a>)Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-4422378433944737036.post-63790746324610575642023-08-12T07:47:00.004-07:002023-08-12T07:47:29.638-07:00Beta-Sitosterol Improves The Liver and Kidney Functioning in Hypertensive Rats in VivoBlood pressure is the force of the blood pushing against the arterial walls. In high blood pressure, the heart has to work harder than normal to pump blood through the circulation system. Over time, high blood pressure has been found to cause damage to the heart and arteries.<div><br />Hypertension or high blood pressure is a condition characterized by persistently or abnormally high blood pressure that leads to raising pressure in your heart.<br /><br />It also is a member of the cluster of metabolic syndrome associated with the risk of diabetes and cardiovascular disease.<br /><br />High blood pressure is a slowly developed condition. Unless the syndrome has caused damage to the blood vessel, otherwise symptoms cannot be detected.<br /><br />If the pressure stays high over time it can cause hardening and stiffening of the arterial wall,, a major risk factor of heart diseases.<br /><br />The ideal blood pressure is more than 120 over 80 and less than 140 over 90 (120/80-140/90), according to the consensus.<br /><br />In the US approximately, one-third of the adults have high blood pressure, affecting over 77 million people in the country.<br /><br />Additionally, among adults aged 20 and older in the United States, in the non-Hispanic whites community, 33.4 percent of men and 30.7 percent of women are infected by the syndrome.<br /><br /><br />High blood pressure can be acute or chronic. Acute high blood pressure most often occurs in people with sudden stress or intense physical exercise. As the heart must pump harder to provide the needs of nutrients and oxygen.<br /><br />Most cases of chronic high blood pressure are associated with an unhealthy lifestyle and chronic diseases such as kidney disease, leading to the onset of strokes and cardiovascular disease.<br /><br /> If you can control your diet, such as making changes to your lifestyle, maintaining an ideal weight, and dieting with low salt, you could do just fine without the drugs.<br /><br /><br />Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, and buckwheat. etc.<br /><br />On finding a potential phytochemical for the prevention and treatment of metabolic syndrome, researchers compared the effects of β-sitosterol (BSS) and lisinopril, antihypertension in rats.<br /><br />According to the tested analysis of rat groups induced hypertension by cadmium chloride treated by BSS and lisinopril, * BSS showed a significant decrease (p<0.05) in the serum creatinine concentration, compared to hypertensive rats.<br /><br />* Lisinopril treatment showed a significant increase (p<0.05) in the activity of oxidative stress markers AST and ALP, compared to normal rats.<br /><br /><br />* Treatment of with BSS and lisinopril showed slight variations in the concentration of serum electrolytes compared with normal and hypertensive rats.<br /><br />* BSS significantly reduced calcium levels compared with the hypertensive group in the activation of oxidative stress.<br /><br />Based on the findings, researchers said, "The study shows that BSS is effective in restoring basal liver and kidney functions in hypertensive rats.<br /><br /><br />Taken altogether, beta-Sitosterol may be considered a supplement for the protection of liver and kidney functioning, pending the confirmation of the larger sample size and multicenter human study.<br /><br />Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.<br /><br /><br /><b><a href="http://9f55846cqkvfueo9njz33azt0t.hop.clickbank.net/?tid=KYLENORTON">Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight</a><br /><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">How To Get Rid Of Eye Floaters </a><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Contrary To Professional Prediction, Floaters </a>C<a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">an Be </a><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Cured Naturally </a><br /><br />Ovarian Cysts And PCOS Elimination<br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Holistic System In Existence That Will Show You. How-To</a><br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Permanently Eliminate All Types of Ovarian Cysts Within 2 Months</a></b><br /><br />Back to Kyle J. Norton's Homepage <a href="http://kylejnorton.blogspot.ca/">http://kylejnorton.blogspot.c</a>a<br /><br /><br />Author Biography<br />Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)<br />Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.<br />Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post<br />Nominated for shorty award over last 4 years<br />Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.<br /><br />Sources<br />(1) Ameliorative effects of β-sitosterol on some biochemical indices of hypertension in Wistar albino rats by Olaiya CO1, Esan AM1, Alabi TD. <a href="https://www.ncbi.nlm.nih.gov/pubmed/26690542">(PubMed)</a></div>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-4422378433944737036.post-7592103987828419452023-05-16T13:23:00.005-07:002023-05-16T13:23:26.615-07:00#Healthyfood #Cranberry Processes Antibiotic Properties, Scientists SayAntibiotics are a group of conventional medicines used for the treatment of bacterial, fungal parasitic,... infections.<br /><br />The medications have no effects on viral infection.<br /><br />Infection is a disease caused by microorganism invasion.<br /><br />After entering the body, the organisms selectively find a specific tissue or organ to start their multiplication.<br /><br />Most infectious diseases can be passed from infected person to person or transmitted by bites from insects or animals.<br /><br />However, acquired infectious diseases can also be caused by ingesting contaminated food or water or being exposed to organisms in the environment.<br /><br />Most organisms before having a chance to induce infection are killed off by the immune system response in the acute phase of infection, by stimulating the production of a proinflammatory cytokine.<br /><br />Unfortunately, if the immune system fails to destroy the invasive organism within a set period of time, normally in a few weeks, it will adapt to the change, causing chronic infection.<br /><br />Antibiotics have been found to cause digestive discomforts such as nausea, and indigestion. vomiting, diarrhea, and bloating. the feeling of fullness, loss of appetite, and stomach cramping or pain, acutely.<br /><br /><br />Chronic use of antibiotics also induces more serious adverse effects, including skin rash, skin allergic reactions, upset stomach, and fungal (yeast) vaginal infections or oral thrush by weakening the immune system.<br /><br />Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.<br /><br />On finding a potential compound for the treatment of infectious diseases, researchers investigated the antibacterial activity of cranberry proanthocyanidin (cPAC) on resistance to tetracycline in Escherichia coli and Pseudomonas aeruginosa.<br /><br /><br />According to the tested assays, cPAC exerted a potentiating effect, both in vitro and in vivo, on a broad range of antibiotic classes against pathogenic E. coli, Proteus mirabilis, and P. aeruginosa.<br /><br />cPAC demonstrated the antibacterial effect through two antibiotic resistance mechanisms, namely, selective membrane permeability, and multidrug efflux pumps.<br /><br />Based on the evidence, researchers said, " The use of cPAC to potentiate antibiotics and mitigate the development of resistance could improve treatment outcomes and help combat the growing threat of antibiotic resistance".<br /><br />Taken altogether, cranberry may be considered an adjunct therapy as an antibiotic against bacterial pathogens, pending the confirmation of the larger sample size and multicenter human study.<br /><br /><b><a href="http://9f55846cqkvfueo9njz33azt0t.hop.clickbank.net/?tid=KYLENORTON">Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight</a><br /><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">How To Get Rid Of Eye Floaters </a><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Contrary To Professionals Prediction, Floaters </a>C<a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">an Be </a><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Cured Naturally </a><br /><br />Ovarian Cysts And PCOS Elimination<br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Holistic System In Existence That Will Show You How To</a><br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Permanently Eliminate All Types of Ovarian Cysts Within 2 Months</a><br /><br />Back to Kyle J. Norton's Homepage <a href="http://kylejnorton.blogspot.ca/">http://kylejnorton.blogspot.c</a>a<br /></b><br /><br />Author Biography<br />Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)<br />Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.<br />Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post<br />Nominated for shorty award over last 4 years<br />Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.<br /><br />Sources<br />(1) Proanthocyanidin Interferes with Intrinsic Antibiotic Resistance Mechanisms of Gram-Negative Bacteria by Maisuria VB1, Okshevsky M1, Déziel E2, Tufenkji N. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/31406662">PubMed</a>)Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-4422378433944737036.post-29506870360082363352023-04-07T16:37:00.009-07:002023-04-07T16:37:53.170-07:00#Tomato Inhibits Colorectal Cancer Cells in Vitro and Vivo, Researchers SayColorectal cancer is a medical condition caused by irregular cell growth in the tissues of the colon or rectum.<br /><br />Most cases of colorectal cancer start in the cell on the surface of the inner lining of the colon or rectum, before penetrating into the deeper layer to induce localized tumors.<br /><br />At the very early stage of colorectal cancer, most patients are asymptomatic due to the very size of the tumor which does not affect the function of the colon or rectum. However, at the advanced stage, the oversize tumor can press on the nearby blood vessels and nerves and affect the organ's functioning, leading to severe pain and bleeding and specific symptoms accompanied by the general symptoms shared by other types of cancer.<br /><br />At this stage, cancer cells can also travel a distance away to infect other healthy tissues and organs, leading to secondary metastasis.<br /><br />According to the statistics provided by the American Cancer Society, colorectal cancer is the third most common cancer diagnosed in both men and women in the United States. Proximately, in 2019, 101,420 new cases of colon cancer and 44,180 rectal cancer will be diagnosed.<br /><br />The lifetime risk of developing colorectal cancer is about 1 in 22 (4.49%) for men and 1 in 24 (4.15%) for women.<br /><br />The 5-year survival rate of people with localized stage colorectal cancer is 90%. However, only 39% of patients are diagnosed at an early stage.<br /><br />Out of many risk factors associated with the onset of colorectal cancer, some researchers suggested that the widespread of colorectal cancer in South Korea may be correlated with the promotion of a high-fat diet over the past few decades, particularly in men.<br /><br /><br />Dr. Kim, Jeehyun, wrote, "In men, total fat intake was not associated with risk of colorectal adenoma. However, the risk of colorectal adenoma increased with higher saturated fatty acid (SFA) intake. The adjusted odds ratio in the highest quintile was 1.71 (95% confidence interval, 1.01–2.91) compared with that in the lowest quintile".<br /><br />Tomato is a red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose<br />and often in the greenhouse.<br /><br />In the urgency to find a potential compound for the treatment of colon cancer, researchers investigated the effects of tomato powder (TP) on the development of azoxymethane (AOM)-induced colorectal cancer in Wistar rats.<br /><br />According to the tested assays, TP added to feed at a 5% rate decreased the rate of aberrant crypt foci (ACF) associated with the early stage of colon cancer development and reduces the development of adenocarcinoma and growth of AOM-induced colorectal cancer in rats.<br /><br /><br />TP supplementation also demonstrated chemopreventive activities against the protein involved in the stimulating production of proinflammatory cytokines in the colon tissues and promoted cancer cell apoptosis.<br /><br />Based on the findings, Dr. Tuzcu M, the lead scientist wrote, "Our findings identify an intimate connection between dietary supplementation of TP and the decreased risk of colorectal cancer in rats".<br /><br /><br />And "suggest that consumption of TP would be a natural candidate for the prevention of colorectal cancer in men".<br /><br />Furthermore, according to the joint study led by the University of Almería, tomatoes showed significant time- and concentration-dependent inhibitory/cytotoxic effects on HT-29 cells.<br /><br />Moreover, adding tomato carotenoids and olive oil to HT-29 cells in cultures demonstrated a better inhibitory effect compared to the application of individual compounds in CCD-18 normal cells.<br /><br /><br />In variety comparison, Racimo tomato displayed the most anti-cancer activity against colorectal cancer cell proliferation compared to others, without affecting the normal CCD-18 cells. <br /><br />In chemical analysis, olive oil and tomato carotenoids inhibited the HT-29 cancer cell proliferation synergistically compared to no effect of other phenolic compounds.<br /><br />Taken altogether, tomatoes alone or combined with olive oil may be considered supplements for the prevention and treatment of colorectal cancer, pending to the confirmation of the larger sample size and multicenter human study.<br /><br /><br /><b><a href="http://9f55846cqkvfueo9njz33azt0t.hop.clickbank.net/?tid=KYLENORTON">Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight</a><br /><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">How To Get Rid Of Eye Floaters </a><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Contrary To Professional's Prediction, Floaters </a>C<a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">an Be </a><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Cured Naturally </a><br /><br />Ovarian Cysts And PCOS Elimination<br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Holistic System In Existence That Will Show You How To</a><br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Permanently Eliminate All Types of Ovarian Cysts Within 2 Months</a><br /><br />Back to Kyle J. Norton's Homepage <a href="http://kylejnorton.blogspot.ca/">http://kylejnorton.blogspot.c</a>a</b><br /><br /><br />Author Biography<br />Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)<br />Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.<br />Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post<br />Nominated for shorty award over last 4 years<br />Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.<br /><br />Sources<br />(1) Tomato powder impedes the development of azoxymethane-induced colorectal cancer in rats through suppression of COX-2 expression via NF-κB and regulating Nrf2/HO-1 pathway by Tuzcu M1, Aslan A, Tuzcu Z, Yabas M, Bahcecioglu IH, Ozercan IH, Kucuk O, Sahin K. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/22859375">PubMed)</a><br />(2) Phytochemical composition and in vitro anti-tumour activities of selected tomatovarieties by Ramos-Bueno RP1, Romero-González R2, González-Fernández MJ1, Guil-Guerrero JL. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/27060896">PubMed)</a><br />(3) Association between dietary fat intake and colorectal adenoma in korean adults<br />A cross-sectional study by Kim, Jeehyun, MD; Oh, Seung-Won, MD, MBA, PhD; Kim, Young-Sun, MD, PhD; Kwon, Hyuktae, MD, MPH, PhD; Joh, Hee-Kyung, MD, MPH, PhD; Lee, Ji-Eun, MD; Park, Danbee, MD; Park, Jae-Hong, MD; Ko, Ah-Ryoung, MD; Kim, Ye-Ji, MD. (<a href="https://journals.lww.com/md-journal/FullText/2017/01060/Association_between_dietary_fat_intake_and.39.aspx">Medicine</a>)Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-4422378433944737036.post-32462651009929552972023-01-10T15:25:00.000-08:002023-01-10T15:25:01.538-08:00Honey, the Best Natural Remedy for Chronic Otitis Externa With No Side EffectsIn seeking natural therapy with no side effects, scientists may have found a herbal medicine for the prevention and treatment of acute otitis externa, according to studies.<div><br />Acute otitis externa is a condition characterized by the inflammation of the ear canal. Most cases of acute acute otitis externa are associated with the infection by Pseudomonas aeruginosa and Staphylococcus aureus due to improper cleaning.<br /><br />However, people with seborrhoeic dermatitis caused by inflammation of greasy areas of the skin can also lead to infection of the ears.<br /><br />The most common symptoms of acute otitis include itching, canal edema, canal erythema, and otorrhea.<br /><br />Most cases of acute otitis externa are healed within days with proper ear drops. However, there is a rare case that the disease may take weeks or months to recover.<br /><br /><br />Chronic otitis externa shares the common symptoms of the acute form, accompanied by water retention and severe ear pain, and temporary loss of hearing, due to building up thick and dry skin can build up inside the ear canal, leading to narrowing the ear canal.<br /><br />Untreated chronic otitis externa can cause deafness.<br /><br />Besides sharing the risk factors with the acute form, otitis externa can also be caused by infection due to the long-term use of hearing aids and earplugs. <br /><br /><br />Unlike the acute form, most cases of otitis externa are treated with steroid drops in addition to antibiotics accompanied by oral intake of pain medications such as ibuprofen.<br /><br /><br />Generally, oral antibiotics are not recommended, however, if the infection has spread beyond the ear canal, oral antibiotics may be applied.<br /><br /><br />According to the statistics, otitis externa affects 1–3% of people in America a year and 95% of people's complaints of the condition are acute.<br /><br /><br />Honey, the rich golden liquid is a miraculous product made by bees using nectar from flowers.<br /><br />The liquid is considered healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.<br /><br />On finding a natural ingredient for the treatment of eczematous external otitis, scientists investigated the antibacterial potential of medical honey eardrops treatment of eczematous external otitis.<br /><br /><br />15 patients diagnosed with recurrent eczematous external otitis were selected and treated with medical honey eardrops for 2 weeks. <br /><br />Honey treatment resulted in less discomfort and itching and decreased signs of eczema with no side effects, according to assays.<br /><br /><br />Although honey eardrops showed a strong in vitro inhibitory activity against all tested strains, they did not eradicate Staphylococcus aureus infection.<br /><br /><br />Honey eardrops also reduced the visual analog scale of ear complaints, and a score of eczema, and increased the eradication of bacterial infection. Most patients in the study, are satisfied with the use of honey eardrops for the treatment of their eczematous external otitis.<br /><br /><br />Dr. Henatsch D, the lead scientist, after taking into account co and confounders said, "The results of this preliminary study indicate a possible role of honey eardrops in eczematous ear disease".<br /><br />Taken altogether, honey may be considered a functional remedy for the treatment of eczematous external otitis, pending the confirmation of a larger sample size and multicenter human study.<br /><br /><br /><b><a href="http://9f55846cqkvfueo9njz33azt0t.hop.clickbank.net/?tid=KYLENORTON">Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight</a><br /><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">How To Get Rid Of Eye Floaters </a><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Contrary To Professionals' Prediction, Floaters </a>C<a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">an Be </a><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Cured Naturally </a><br /><br />Ovarian Cysts And PCOS Elimination<br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Holistic System In Existence That Will Show You How To</a><br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Permanently Eliminate All Types of Ovarian Cysts Within 2 Months</a><br /><br />Back to Kyle J. Norton's Homepage <a href="http://kylejnorton.blogspot.ca/">http://kylejnorton.blogspot.c</a>a<br /></b><br /><br />Author Biography<br />Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)<br />Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.<br />Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post<br />Nominated for shorty award over last 4 years<br />Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.<br /><br />References<br />(1) Treatment of Recurrent Eczematous External Otitis with Honey Eardrops: A Proof-of-Concept Study by Henatsch D1, Nabuurs CH1, van de Goor RM1, Wolffs PF2, Stokroos RJ. <a href="https://www.ncbi.nlm.nih.gov/pubmed/28695767">(PubMed)</a><br />(2) Alternative Treatments for Atopic Dermatitis: An Update by Shi K1, Lio PA. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/30511123">PubMed</a>)<br />(2) Acute Otitis Externa: An Update by PAUL SCHAEFER, MD, PhD, and REGINALD F. BAUGH, MD. (<a href="https://www.aafp.org/afp/2012/1201/p1055.html">AAFP</a>)</div>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-4422378433944737036.post-80787403771884703472022-12-03T08:42:00.002-08:002022-12-03T08:42:14.901-08:00The Possible Effects of Healthy Veggie Broccoli on Hypertension, Researchers SayBlood pressure is the force of the blood pushing against the arterial walls. In high blood pressure, the heart has to work harder than normal to pump blood through the circulation system. Over time, high blood pressure has been found to cause damage to the heart and arteries.<div><br />Hypertension or high blood pressure is a condition characterized by persistent high blood pressure.<br /><br />In the US approximately, one-third of adults have high blood pressure, affecting over 77 million people in the country.<br /><br />Additionally, among adults aged 20 and older in the United States, in the non-Hispanic whites community, 33.4 percent of men and 30.7 percent of women are infected by the syndrome.<br /><br />High blood pressure is a slowly developed condition. Unless the syndrome has caused damage to the blood vessel, otherwise symptoms cannot be detected.<br /><br /><br />High blood pressure is a chronic condition associated with an unhealthy lifestyle and chronic diseases such as kidney disease, leading to the onset of strokes and cardiovascular disease.<br /><br />In other words, if you can control your diet, such as making changes to your lifestyle, maintaining an ideal weight, and dieting with low salt, you could do just fine without the drugs.<br /><br />The cause of high blood pressure is a result hardening and thickening of the arteries (atherosclerosis), due to the slow progression of plaques accumulated on the wall of the arteries.<br /><br /><br />According to the American Heart Association (AHA) patients with blood pressure that is higher than 130 over 80 millimeters of mercury (mmHg) is considered to have hypertension.<br /><br />Untreated chronic high blood pressure may induce complications of heart attack, stroke, and other health conditions.<br /><br /><br />Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae. The vegetable has large flower heads, usually green in color and the mass of flower heads is surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.<br /><br /><br />In finding a potential plant that processes anti-high blood pressure, researchers examined the broccoli protein hydrolysates' inhibitory activity in vitro and hypotensive effect in vivo.<br /><br /><br />According to the results of the analysis,<br />* Three ACE inhibitory peptides were isolated and identified as IPPAYTK, LVLPGELAK, and TFQGPPHGIQVER, and their inhibitory IC50 values were 23.5, 184.0, and 3.4 μM, respectively.<br /><br /><br />* LVLPGE and LAK, two novel peptides exhibited the highest ACE inhibitory activity associated with lowering hypertension with IC50 values of 13.5 and 48.0 μM, respectively.<br /><br /><br />* Moreover, the hypotensive effect of the peptides was assessed after oral administration to spontaneous hypertensive rats (SHRs).<br /><br /><br />Collectively, researchers said, "LVLPGE and LAK demonstrated a significant hypotensive effect in vivo. Protein from broccoli may thus constitute a potential antihypertensive peptide source".<br /><br /><br />Taken altogether, broccoli may be considered a functional food for the prevention and treatment of hypertension, pending the confirmation of the larger sample size and multicenter human study.<br /><br /><b><br /><a href="http://9f55846cqkvfueo9njz33azt0t.hop.clickbank.net/?tid=KYLENORTON">Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight</a><br /><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">How To Get Rid Of Eye Floaters </a><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Contrary To Professionals' Prediction, Floaters </a>C<a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">an Be </a><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Cured Naturally </a><br /><br />Ovarian Cysts And PCOS Elimination<br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Holistic System In Existence That Will Show You How-To</a><br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Permanently Eliminate All Types of Ovarian Cysts Within 2 Months</a><br /><br />Back to Kyle J. Norton's Homepage <a href="http://kylejnorton.blogspot.ca/">http://kylejnorton.blogspot.c</a>a</b><br /><br /><br />Author Biography<br />Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)<br />Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.<br />Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post<br />Nominated for shorty award over last 4 years<br />Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.<br /><b><br />Sources</b><br />(1) In Vitro and in Vivo Studies on the Angiotensin-Converting Enzyme Inhibitory Activity Peptides Isolated from Broccoli Protein Hydrolysate by Dang Y1, Zhou T2, Hao L1, Cao J1, Sun Y1, Pan D. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/31184153">PubMed</a>)</div>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-4422378433944737036.post-69868638612954357612022-11-27T08:30:00.002-08:002022-11-27T08:30:17.477-08:00#Healthyfood Red Cabbage Processes Anti-Bacteria Infection, Researchers SayInfectious diseases are medical conditions caused by pathogenic microorganisms, including bacteria, viruses, parasites, or fungi.<br />Most cases of infectious diseases are contagious by spreading directly or indirectly, from one person to another.<br /><br />In other words, if you kiss, or are coughed or sneezed on by an infectious person, you are at risk of developing the same infectious disease.<br /><br />According to the statistic provided by the World Health Organization, 3 infectious diseases were ranked in the top ten causes of death worldwide in 2016.<br /><br />More precisely, lower respiratory infections, diarrheal diseases, and tuberculosis induced 3.0 million, 1.4 million, and 1.3 million deaths, respectively.<br /><br />Conventionally, most cases of infectious diseases except those caused by viruses are treated with antibiotics.<br /><br />Bacteria is a type of biological cell consisting of a single cell with a simple internal structure.<br /><br />The most common diseases caused by bacteria include strep throat, urinary tract infections, and tuberculosis.<br /><br />Infection occurs when the bacteria successfully invade the body and start to multiply. Most cases of infectious diseases caused by bacteria are treated with antibiotics.<br /><br />And, most cases of infectious disease are transmitted by airborne you can get sick if you breathe into the air that carries infectious bacteria in air particles, vector-borne if you are stunk by the insect that the bacteria, and vehicle-borne if you are eating food or carrying the materials contaminated by the bacteria.<br /><br />Most cases of bacterial invasion are met with the first line of immune white blood cells. In the active division of bacteria in the acute phase of infection, the immune system response activated the production of the proinflammatory cytokine to the site of infection with an aim to kill off all bacteria.<br /><br />However, if the immune fails to kill off all the bacteria within the 3 - 8 weeks period, it then will adapt to the change, leading to chronic inflammatory and infectious diseases.<br /><br />Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem with a crowded mass of leaves, usually green but in some varieties, it may be red or purplish.<br /><br />To find a natural wholefood for the prevention of infectious disease, researchers examined the B. oleracea L (red cabbage) anti-microbial activity.<br /><br />In 22 pathogenic bacteria and fungi, B. oleracea L (red cabbage) demonstrated antibacterial (Methicillin-resistant Staphylococcus aureus, Escherichia coli O157: H7, Pseudomonas aeruginosa, Klebsiella pneumonia, Staphylococcus aureus, and Salmonella enterica serovar Typhimurium) and antifungal (Trichophyton rubrum and Aspergillus terreus) activities at a minimum bactericidal concentration (MBC) and the minimum fungicidal concentration (MFC), respectively.<br /><br /><br />In Chemical analysis, the potent antimicrobial action from B. oleracea L (red cabbage) was attributed to the rich source of phenolic compounds, anthocyanins.<br /><br />Based on the results, researchers wrote, "This extract is potentially novel for future antimicrobials, inexpensive, and readily available at a large scale for pharmaceutical companies for further investigation and processing".<br /><br />Taken altogether, red cabbage may be considered a natural antibiotic, pending the confirmation of the larger sample size and multicenter human study.<br /><br /><b><br /><a href="http://9f55846cqkvfueo9njz33azt0t.hop.clickbank.net/?tid=KYLENORTON">Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight</a><br /><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">How To Get Rid Of Eye Floaters </a><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Contrary To Professional's Prediction, Floaters </a>C<a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">an Be </a><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Cured Naturally </a><br /><br />Ovarian Cysts And PCOS Elimination<br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Holistic System In Existence That Will Show You How-To</a><br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Permanently Eliminate All Types of Ovarian Cysts Within 2 Months</a><br /><br />Back to Kyle J. Norton's Homepage <a href="http://kylejnorton.blogspot.ca/">http://kylejnorton.blogspot.c</a>a<br /></b><br /><br />Author Biography<br />Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)<br />Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.<br />Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post<br />Nominated for shorty award over last 4 years<br />Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.<br /><br />Sources<br />(1) Inhibition of Growth of Highly Resistant Bacterial and Fungal Pathogens by a Natural Product by Rand R Hafidh,1,2 Ahmed S Abdulamir,2,3 Law Se Vern,4 Fatimah Abu Bakar,4,* Faridah Abas,4 Fatemeh Jahanshiri,5 and Zamberi Sekawi. (<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171003/">PMC</a>)Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-4422378433944737036.post-68247484981075592532022-11-22T03:48:00.008-08:002022-11-22T03:50:07.269-08:00#Healthy #Tomato/Lycopene the Anti Cancers Functional Food<br />Cancers are a class of diseases caused by irregular cell growth in the tissue or organ in the body.<br /><br />According to the Canadian Cancer Society, in 2017, over 200,000 new cases of cancer were diagnosed and 80,800 patients died from the disease in the same year.<br /><br />Lung, colorectal, breast, and prostate cancer accounted for about half of all cancer diagnoses and deaths.<br />Believe it or not, 1 in 2 Canadian adults will develop cancer in their lifetimes and 1 in 4 will die of the disease.<br /><br /><br />At the early stage, patients with cancer may not experience any symptoms due to the very small size of the tumor and the cancer is still on the surface in the inner lining tissues. However, at the late stage after colonizing the complete organ, cancer cells not can travel a distance away from the originated site to affect other healthy tissue and organ, they can also cause some related and specific symptoms accompanied by general symptoms associated with other types of cancer.<br /><br /><br />Cancer is classified by the followings* Size of the cancer<br /><br />* Invasive or not<br /><br />* Whether cancer has spread to the lymph nodes<br /><br />* Whether cancer has spread to distant parts or organs of the body.<br /><br />There are 4 stages of breast cancer in TNM rating (where T is referred for tumor size, N is referred for Lymph Node status, and M is referred for invasive or not)<br /><br />Where<br /># T: Tumor Size is divided into four classes: T-1 is between 0 - 2 cms, T-2 is between 2 - 5 cms, T-3 is > 5cms, and T-4 is a tumor of any size growing into the chest wall or skin, including inflammatory breast cancer.<br />#N: No swollen nodes: N-0, some swelling but negative node (not cancerous): N-1a, swelling nodes and positive node (cancerous): N-1b, quite swollen and bunched together: N-2, quite swollen and near the collarbone: N-3.<br /># M: if no cancer cell is found: M-0, cancer cells found: M-1.<br /><br />The stages of cancer are<br />* Stage 1T-1 tumor and clear lymph nodes with no evidence of spreading (M-0), or T-1N-0M-0.<br />* Stage 2<br />Stage 2 is the combination of a combination of T-1, T-2, or T-3 tumor, N-0. N-1a and N-1b but no spreading (M-0)<br />* Stage 3<br />Stage 3 is the combination of all T or N but no spreading (M-0)<br />* Stage 4<br />Stage 4 is the combination of T, N-1a, N-1b, N-2, N-3, and M-1<br /><br /><br />Tomato is red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose<br />and often in the greenhouse.<br /><br />In the urgency to find a potential ingredient for the treatment of cancer with little or no side effect, researchers examined the effect of a novel strategy of formulating the lycopene-loaded whey protein isolate nanoparticles (LYC-WPI-NPs) ability for adenosine deaminase inhibition of the regression of the tumor with the percent lycopene entrapment in the range to 50 and 65%.<br /><br />In the chemical release analysis, LYC-WPI-NPs enhanced the oral bioavailability of lycopene by controlling its release through the absorption in the lymphatic pathways.<br /><br />According to the MTT-based colorimetric assay, LYC-WPI-NPs exerted significant cytotoxicity against MCF-7 breast cancer cells in vitro.<br /><br />In an animal model-induced breast cancer, LYC-WPI-NPsd also demonstrated its prophylactic anticancer efficacy without causing the death of normal cells.<br /><br />Based on the findings, researchers wrote in the final paper, "Conclusively, it may quite reasonable that lycopene loaded protein nanoparticles are competent to improve the biopharmaceutical attributes of lycopene and demonstrated prophylactic anticancer activity, decrease tumor proliferation and increase the survival rate of treated animals".<br /><br /><br />In other words, LYC-WPI-NPs significantly enhanced the lycopene anti-cancer biopharmaceutic activity compared to oral administration as seen in an animal model.<br /><br />Taken altogether, tomatoes may be considered supplements for the prevention and treatment of cancer, pending the confirmation of the larger sample size and multicenter human study.<br /><br />Intake of lycopene in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.<br /><b><br /><a href="http://9f55846cqkvfueo9njz33azt0t.hop.clickbank.net/?tid=KYLENORTON">Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight</a><br /><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">How To Get Rid Of Eye Floaters </a><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Contrary To Professional Prediction, Floaters </a>C<a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">an Be </a><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Cured Naturally </a><br /><br />Ovarian Cysts And PCOS Elimination<br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Holistic System In Existence That Will Show You How To</a><br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Permanently Eliminate All Types of Ovarian Cysts Within 2 Months</a><br /><br />Back to Kyle J. Norton's Homepage <a href="http://kylejnorton.blogspot.ca/">http://kylejnorton.blogspot.c</a>a<br /></b><br /><br />Author Biography<br />Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)<br />Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.<br />Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post<br />Nominated for shorty award over last 4 years<br />Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.<br /><br />Sources<br />(1) Tomato (Solanum lycopersicum) Carotenoids and Lycopenes Chemistry; Metabolism, Absorption, Nutrition, and Allied Health Claims--A Comprehensive Review by Perveen R1, Suleria HA, Anjum FM, Butt MS, Pasha I, Ahmad S. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/24915375">PubMed</a>)<br />(2) Lycopene loaded whey protein isolate nanoparticles: An innovative endeavor for enhanced bioavailability of lycopene and anti-cancer activity by Jain A1, Sharma G2, Ghoshal G3, Kesharwani P4, Singh B5, Shivhare US4, Katare OP. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/29715533">PubMed)</a>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-4422378433944737036.post-46686927075332805432022-10-22T08:08:00.004-07:002022-10-22T08:08:16.308-07:00Healthy Food Potatoes (Solanum), Process a Strong Antioxidant PropertyAntioxidants are stable atom that plays a critical role in protecting the body against the attack of free radicals.<div><br />In other words, antioxidants inhibited the onset of free radicals before they can cause a chain reaction in facilitating oxidative stress that causes damage to proteins, lipids, and cell DNA.<br /><br />Oxidative stress is a result of an imbalance in the ratio of free radicals and antioxidants in the body.<br /><br />Free radicals are highly reactive molecules with an unpaired electron on the outer ring of the atom.<br /><br />Due to their nature to become stable, free radicals readily donate or steal an electron from other molecules, leading to the chain of domino effect that can not be stopped until either the electrons are paired or inhibited by antioxidants.<br /><br />This chain of reaction is the cause of oxidative stress, a condition associated with either overexpression of free radicals or depletion of antioxidant enzymes produced by the host organs.<br /><br />Overexpression of free radicals is known to cause damage in contributing to the etiology of many chronic health problems such as cardiovascular and inflammatory disease, cataracts, and cancer.<br />Antioxidants, on the other hand, are stable molecules with a unique function in the inhibition of oxidation.<br /><br />Antioxidants can either be produced by the liver or intake from dietary sources. Under normal conditions, antioxidant enzymes produced by the body in a healthy individual are good enough to counter the bombardment of free radical attacks.<br /><br />However, in people with a weakened immune system, intake of dietary sources of antioxidants may be necessary.<br /><br />There are 3 main types of antioxidants found in nature, including antioxidant enzymes produced by the host, including superoxide dismutase (SOD), glutathione peroxidase, glutathione reductase, and catalases, antioxidants vitamins, that may be injected from dietary sources such as fruits and vegetables, including vitamins A, C, D, and E and antioxidant-phytochemicals found in the plant including second metabolites.<br /><br />Potato is the genus Solanum and belongs to the family Solanaceae. It is a good source of protein and according to the statistic, the annual diet of an average global citizen is about 33 kg (72.6 Lbs) of potato. The root veggie now is growing worldwide in a suitable climate for commercial profits and health benefits, thus its consumption is extremely variable and rapidly changing.<br /><br />In finding a potential plant for the prevention and treatment of diseases associated with oxidative stress, researchers examined the potential of peptide fractions isolated from dehydrated potatoes on intestinal epithelial cells (IEC-6) under oxidative and inflammatory conditions.<br /><br />Based on the results of differentiation,* Peptide fractions demonstrated a significantly inhibit the pro-inflammatory protein expression such as tumor necrosis factor-α and cycloxygenase-2 and inducible nitric oxide synthase.<br /><br />* More importantly, the tested peptides also showed significant antioxidant activity by reducing reactive oxygen species (ROS) release induced from mitochondria, and nitrotyrosine formation<br /><br />* Furthermore, the applications also increase the antioxidant response by heme oxygenase-1 and superoxide dismutase expression.<br /><br />Additionally, the peptide fractions were able to significantly increase wound repair in IEC-6 induced by oxidative-inflammatory damage.<br /><br />Collectively, researchers said, "The obtained results indicate the anti-inflammatory and antioxidant potential of dehydrated potatoes at the intestinal level".<br /><br /><br />Taken altogether, potatoes may be considered a functional food for the prevention and treatment of diseases associated with oxidative stress, pending the confirmation of the larger sample size and multicenter human study.<br /><br /><br /><b><a href="http://9f55846cqkvfueo9njz33azt0t.hop.clickbank.net/?tid=KYLENORTON">Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight</a><br /><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">How To Get Rid Of Eye Floaters </a><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Contrary To Professionals' Prediction, Floaters </a>C<a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">an Be </a><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Cured Naturally </a><br /><br />Ovarian Cysts And PCOS Elimination<br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Holistic System In Existence That Will Show You How-To</a><br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Permanently Eliminate All Types of Ovarian Cysts Within 2 Months</a><br /><br />Back to Kyle J. Norton's Homepage <a href="http://kylejnorton.blogspot.ca/">http://kylejnorton.blogspot.c</a>a</b><br /><br /><br />Author Biography<br />Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)<br />Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.<br />Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post<br />Nominated for shorty award over last 4 years<br />Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.<br /><br />Sources<br />(1) Anti-Inflammatory and Antioxidant Properties of Dehydrated Potato-Derived Bioactive Compounds in Intestinal Cells by Basilicata MG1,2, Pepe G1, Rapa SF1, Merciai F1,2, Ostacolo C3, Manfra M4, Di Sarno V1, Autore G1, De Vita D5, Marzocco S1, Campiglia P. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/31816826">PubMed</a>)</div>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-4422378433944737036.post-35507460479712220852022-10-07T15:57:00.006-07:002022-10-07T15:57:41.499-07:00The Possible Effects of Healthy Veggie Broccoli on HypertensionBlood pressure is the force of the blood pushing against the arterial walls. In high blood pressure, the heart has to work harder than normal to pump blood through the circulation system. Over time, high blood pressure has been found to cause damage to the heart and arteries.<div><br />Hypertension or high blood pressure is a condition characterized by persistent high blood pressure.<br /><br />In the US approximately, one-third of adults have high blood pressure, affecting over 77 million people in the country.<br /><br />Additionally, among adults aged 20 and older in the United States, in the non-Hispanic whites community, 33.4 percent of men and 30.7 percent of women are infected by the syndrome.<br /><br />High blood pressure is a slowly developed condition. Unless the syndrome has caused damage to the blood vessel, otherwise symptoms cannot be detected.<br /><br />High blood pressure is a chronic condition associated with an unhealthy lifestyle and chronic diseases such as kidney disease, leading to the onset of strokes and cardiovascular disease.<br /><br />In other words, if you can control your diet, such as making changes to your lifestyle, maintaining an ideal weight, and dieting with low salt, you could do just fine without the drugs.<br /><br />The cause of high blood pressure is a result hardening and thickening of the arteries (atherosclerosis), due to the slow progression of plaques accumulated on the wall of the arteries.<br /><br /><br />According to the American Heart Association (AHA) patients with blood pressure that is higher than 130 over 80 millimeters of mercury (mmHg) are considered to have hypertension.<br /><br />Untreated chronic high blood pressure may induce complications of heart attack, stroke, and other health conditions.<br /><br /><br />Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae. The vegetable has large flower heads, usually green in color and the mass of flower heads is surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.<br /><br /><br />In finding a potential plant that processes anti-high blood pressure, researchers examined the broccoli protein hydrolysates' inhibitory activity in vitro and hypotensive effect in vivo.<br /><br /><br />According to the results of the analysis,<br />* Three ACE inhibitory peptides were isolated and identified as IPPAYTK, LVLPGELAK, and TFQGPPHGIQVER, and their inhibitory IC50 values were 23.5, 184.0, and 3.4 μM, respectively.<br /><br />* LVLPGE and LAK, two novel peptides exhibited the highest ACE inhibitory activity associated with lowering hypertension with IC50 values of 13.5 and 48.0 μM, respectively.<br /><br />* Moreover, the hypotensive effect of the peptides was assessed after oral administration to spontaneous hypertensive rats (SHRs).<br /><br />Collectively, researchers said, "LVLPGE and LAK demonstrated a significant hypotensive effect in vivo. Protein from broccoli may thus constitute a potential antihypertensive peptide source".<br /><br /><br />Taken altogether, broccoli may be considered a functional food for the prevention and treatment of hypertension, pending the confirmation of the larger sample size and multicenter human study.<br /><br /><b><br /><a href="http://9f55846cqkvfueo9njz33azt0t.hop.clickbank.net/?tid=KYLENORTON">Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight</a><br /><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">How To Get Rid Of Eye Floaters </a><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Contrary To Professional's Prediction, Floaters </a>C<a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">an Be </a><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Cured Naturally </a><br /><br />Ovarian Cysts And PCOS Elimination<br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Holistic System In Existence That Will Show You How-To</a><br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Permanently Eliminate All Types of Ovarian Cysts Within 2 Months</a><br /><br />Back to Kyle J. Norton's Homepage <a href="http://kylejnorton.blogspot.ca/">http://kylejnorton.blogspot.c</a>a</b><br /><br /><br />Author Biography<br />Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)<br />Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.<br />Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post<br />Nominated for shorty award over last 4 years<br />Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.<br /><br />Sources<br />(1) In Vitro and in Vivo Studies on the Angiotensin-Converting Enzyme Inhibitory Activity Peptides Isolated from Broccoli Protein Hydrolysate by Dang Y1, Zhou T2, Hao L1, Cao J1, Sun Y1, Pan D. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/31184153">PubMed</a>)</div>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-4422378433944737036.post-15162777867092321942022-10-01T08:16:00.005-07:002022-10-01T08:18:06.132-07:00Cabbage Protects the Cell's Integrity Against Oxidative StressOxidative stress is a condition caused by an imbalance of the ratio of free radicals and antioxidants in the body.<br />In other words, oxidative stress is either caused by overexpression of free radicals or depletion of antioxidant enzymes in the body.<br /><br />Some researchers suggested that oxidative stress may also arise due to the chain reaction of free radicals in which free radicals donate or intercept an electron from other stable molecules.<br /><br />Long-term oxidative stress present in the body can cause protein and lipid damage and alternation of cell DNA, leading to the onset of chronic diseases, including cardiovascular disease, diabetes, and cancer.<br /><br />More precisely, exogenous factors, such as cigarette smoke, and endogenous factors, such as the oxidative burst from activated macrophages are some of the factors involved in the risk of oxidative stress.<br /><br />Free radicals are highly reactive molecules with an unpaired electron on the outer ring of the atom.<br /><br />Due to its nature to become stable, free radicals readily donate or steal an electron from other molecules, leading to the chain of domino effect that can not be stopped until either the electrons are paired or inhibited by antioxidants.<br />This chain of reaction is the cause of oxidative stress, a condition associated with either overexpression of free radicals or depletion of antioxidant enzymes produced by the host organs.<br /><br />Antioxidants are stable atom that plays a critical role in protecting the body against the attack of free radicals.<br /><br />In other words, antioxidants inhibited the onset of free radicals before they can cause a chain reaction in facilitating protein, lipid, and cell damage.<br /><br />Antioxidants can either be produced by the liver or intake from dietary sources. Under normal conditions, antioxidant enzymes produced by the body in a healthy individual are good enough to counter the bombardment of free radical attacks.<br /><br /><br />Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem with a crowded mass of leaves, usually green but in some varieties, it may be red or purplish.<br /><br />On findings of a natural whole for the prevention and treatment of diseases associated with oxidative stress, researchers investigated the effects of red cabbage anthocyanin (RCA)-enriched extract on H₂O₂ expression on HepG2 cells.<br /><br />According to chemical analysis, all derivatives of cyanidin (268 ± 2 μg/mg) found in RCA, mainly with 19% nonacylated, 51% monoacylated, and 31% diacylated structures with ferulic, sinapic, p-coumaric, and caffeic acids exerted antioxidant activity against the oxidative stress induced by the injection of H₂O₂.<br /><br />Furthermore, the application of RCA extracts markedly ameliorated cell apoptosis and improved viability.<br /><br />Moreover, in another study, cabbage extract protected against H2O2-induced cell death and did not elicit any cytotoxic effects by suppressing ROS production and increasing the expression of antioxidant proteins (SOD-1, catalase, and GPx) produced by the host.<br /><br /><br />In oxidative stress-exposed H9c2 cells, the protective effects of cabbage extract also inhibited apoptotic responses and activation of MAPK proteins (ERK1/2, JNK, and p-38) involved in the resistance of apoptosis by preserving mitochondrial functions.<br /><br />Based on the results, researchers wrote, "cabbage extract protects against oxidative stress and suggests that it can be used as an alternative therapeutic strategy to prevent the oxidative stress in the heart".<br /><br />Taken altogether, cabbage may be used as a functional food for the prevention and treatment of diseases associated with oxidative stress, pending the confirmation of the larger sample size and multicenter human study.<br /><br /><b><a href="http://9f55846cqkvfueo9njz33azt0t.hop.clickbank.net/?tid=KYLENORTON">Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight</a><br /><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">How To Get Rid Of Eye Floaters </a><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Contrary To Professionals' Prediction, Floaters </a>C<a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">an Be </a><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Cured Naturally </a><br /><br />Ovarian Cysts And PCOS Elimination<br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Holistic System In Existence That Will Show You How-To</a><br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Permanently Eliminate All Types of Ovarian Cysts Within 2 Months</a><br /><br />Back to Kyle J. Norton Homepage <a href="http://kylejnorton.blogspot.ca/">http://kylejnorton.blogspot.c</a>a</b><br /><br /><br />Author Biography<br />Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)<br />Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.<br />Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post<br />Nominated for shorty award over last 4 years<br />Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.<br /><br />Sources<br />(1) Characterization of Purified Red Cabbage Anthocyanins: Improvement in HPLC Separation and Protective Effect against H₂O₂-Induced Oxidative Stress in HepG2 Cells by Fang S1, Lin F2, Qu D3, Liang X4, Wang L. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/30602654">PubMed</a>)<br />(2) Cabbage (Brassica oleracea var. capitata) Protects against H2O2-Induced Oxidative Stress by Preventing Mitochondrial Dysfunction in H9c2 Cardiomyoblasts by Yang DK. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/30158990">PubMed</a>)Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-4422378433944737036.post-9679794269438892162022-09-25T09:11:00.004-07:002022-09-25T09:11:12.770-07:00Tomatoes Kill Bacterial Staphylococcus Aureus Against the Onset of Pneumonia<br /><br /> Pneumonia is a medical condition associated with the infection of the lung. In adults, the most common cause of pneumonia is bacterial infections such as Staphylococcus aureus.<br /><br />Viruses or fungi also have been found to induce the onset of the disease.<br /><br />The most common symptoms of pneumonia are persistent coughing with phlegm (mucus) fever, sweating, chills, and chest pain. However, depending on the types of pathogens that cause the infection.<br /><br />In severe cases, pneumonia is life-threatening. Some patients at this stage also experience persistent shortness of breath due to severe inflammation in the air sacs of the lungs.<br /><br />According to epidemiological studies, most cases of pneumonia are acquired from either hospitals or communities caused by people who have the disease.<br /><br /><br />Some researchers suggested people who have weakened such as elderly or immature immune systems such as babies and underage children are more prone to the disease.<br /><br /><br />Dr. Sanjay Sethi at the University at Buffalo SUNY wrote, "Pneumonia is an infection of the lungs. Pneumonia in people whose immune system is weakened or impaired (for example, by AIDS, cancer, organ transplantation, or the use of certain drugs) is often caused by different organisms than those that cause pneumonia in healthy people".<br /><br /><br />In other words, people who are treated with chemotherapy drugs due to cancer or immune suppressants, and diseases associated with immunity are susceptible to pneumonia developing.<br /><br />Most cases of pneumonia are treated with antibiotics. Depending on the condition, treatment may include medicine for reduced coughing, pain, and fever with an aim to improve the patient's quality of life.<br /><br />If you are taking certain types of antibiotics for the treatment of pneumonia, please make sure you know all the side effects for preventive measures.<br /><br />Tomato is red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose<br />and often in the greenhouse.<br /><br />On finding a potential ingredient for the treatment of Staphylococcus aureus pneumonia, researchers examined the effect of naringenin found abundantly in tomatoes.<br /><br />In the Staphylococcus aureus pneumonia model, naringenin protected the lung cells' integrity and viability by inhibiting the production of α-toxin.<br /><br /><br />Where α-toxin is an essential virulence factor found in patients with Staphylococcus aureus pneumonia.<br /><br />Furthermore, at 16 μg/ml of naringenin, treatment organisms showed reduced expression of α-toxin significantly compared to the untreated group.<br /><br /><br /><br />Moreover, in vivo, a mouse model of S. aureus pneumonia treated with naringenin demonstrated a significant effect in attenuating symptoms of lung injury and inflammation against infection.<br /><br /><br />In other words, naringenin acted as a natural antibiotic in preventing the overexpression of α-toxin produced by Staphylococcus aureus through its antibacterial activity.<br /><br /><br />Based on the findings, Dr. Zhang Y, the lead scientist after taking into account co and confounders wrote in the final report, "These results suggest that naringenin is a promising agent for the treatment of S. aureus infection".<br /><br />Taken altogether, tomatoes may be considered supplements for the prevention and treatment of Staphylococcus aureus pneumonia, pending the confirmation of the larger sample size and multicenter human study.<br /><br />Intake of naringenin in the form of a supplement should be taken with extreme care to prevent overdose and acute liver toxicity.<br /><b><br /><a href="http://9f55846cqkvfueo9njz33azt0t.hop.clickbank.net/?tid=KYLENORTON">Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight</a><br /><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">How To Get Rid Of Eye Floaters </a><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Contrary To Professionals' Prediction, Floaters </a>C<a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">an Be </a><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Cured Naturally </a><br /><br />Ovarian Cysts And PCOS Elimination<br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Holistic System In Existence That Will Show You How To</a><br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Permanently Eliminate All Types of Ovarian Cysts Within 2 Months</a><br /><br />Back to Kyle J. Norton Homepage <a href="http://kylejnorton.blogspot.ca/">http://kylejnorton.blogspot.c</a>a<br /></b><br /><br />Author Biography<br />Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)<br />Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.<br />Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post<br />Nominated for shorty award over last 4 years<br />Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.<br /><br />Sources<br />(1) Inhibition of α-toxin production by subinhibitory concentrations of naringenin controls Staphylococcus aureus pneumonia by Zhang Y1, Wang JF, Dong J, Wei JY, Wang YN, Dai XH, Wang X, Luo MJ, Tan W, Deng XM, Niu XD. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=Tomatoes+Staphylococcus+aureus+pneumonia">PubMed</a>)<br />(2) Pneumonia in Immunocompromised People By Sanjay Sethi , MD, University at Buffalo SUNY. (<a href="https://www.msdmanuals.com/home/lung-and-airway-disorders/pneumonia/pneumonia-in-immunocompromised-people">MSD Manual</a>)Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-4422378433944737036.post-18275309296984593222022-09-16T08:10:00.001-07:002022-09-16T08:10:12.160-07:00Chronic Pain in Autosomal recessive polycystic kidney disease The Smoothie of Cherries, Ginger and Peppermint for Prevention and Treatment of chronic pain in Autosomal recessive polycystic kidney disease<div style="background-color: white; font-family: "times new roman";"><b>Kyle J. Norton</b></div>
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<span style="font-family: "times new roman";">The finding of a natural source for the treatment of Autosomal recessive polycystic kidney disease has been running into many obstacles, many ingredients shown initially with promising results in animal studies have not produced the same potential in large sample sizes and multi centers human trials.</span><br />
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Autosomal recessive polycystic kidney disease is an inherited disease (Mutations in the PKHD1)causing abnormal functions of the liver and reno-inducing morbidity and mortality in children.<br />
Until today, there is no cure, or treatment options for autosomal recessive polycystic kidney disease, depending on complications, such as chronic pain.</div>
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<b>The smoothie for people with chronic pain in </b><b style="background-color: white; font-family: "times new roman";">Autosomal recessive polycystic kidney disease</b><br />
Yield: 2 servings (about 8 ounces each)<br />
1 1/2 cups cherries cups pineapple<br />
1 slice of ginger root<br />
1 cup of peppermint herbal tea<br />
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1. Place all ingredients in a blender and puree for about 1 minute<br />
2. Blend on high speed for about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drinks if needed<br />
3. Serve immediately<br />
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Cherries(1), ginger(4), and peppermint(7) may be the next combination of therapeutic ingredients as a pain reliever for the treatment of chronic pain in patients with autosomal recessive polycystic kidney disease.<br />
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Cherry, a fleshy drupe, is the fruit of many plants of the genus Prunus cultivated all over the world for commercial profit due to its health potential.<br />
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In a randomized double-blind crossover study of 58 non-diabetic patients, oral administration of cherry juice improved the Western Ontario McMaster Osteoarthritis Index (WOMAC) scores, inducing symptom relief, including pain for patients with mild to moderate knee Osteoarthritis, through lowering the C-reactive protein CRP levels(1). According to the Oregon Health & Science University, the study of fifty-four healthy runners with ingesting 355 mL bottles of tart cherry juice twice daily for 7 days, during a strenuous running event can minimize post-run muscle pain(3).<br />
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Dr. Kuehl KS said, "Tart cherries appear to possess similar effectiveness in treating the inflammatory reaction seen in both acute and chronic pain syndromes encountered among athletes and non-athletes with chronic inflammatory disease")2) of that may be used as an antioxidant and anti-inflammatory ingredient on prevention, treatment, and recovery of soft tissue injury and pain.<br />
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Ginger (Zingiber officinale) or ginger root is the genus Zingiber, belongings to the family Zingiberaceae, native to Tamil, used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.<br />
In primary dysmenorrhea patients, ginger is effective in pain relief without inducing adverse effects and may be used as an alternative treatment for primary dysmenorrhea, according to the Mazandaran University of Medical Sciences(4) and treatment of ginger in students with primary dysmenorrhea for 5 days also showed a statistically significant effect on relieving intensity and duration of pain, the Shahid University, the study suggested(5).<br />
Furthermore, in osteoarthritic patients, Dr. Therkleson T said," ginger therapy activated a marked relief of osteoarthritis symptoms that progressively improved over the 24 weeks, with no negative effects reported. Ginger therapy needs to be considered by nurses caring for specific personality types with osteoarthritis"(6).<br />
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Peppermint is a hybrid mint with small purple or white flowers and downy leaves, in the genus Mentha, belonging to the family Lamiaceae, native to Europe. The herb has been used in folk medicine as an analgesic, antiseptic, antispasmodic, decongestant, and agent and to relieve gas, nausea, and stomach pain due to irritable bowel, intestinal cramps, indigestion, infection, etc<br />
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According to the Translational Research Center for Gastrointestinal Disorders (TARGID), peppermint oil, with antispasmodics may be considered the first-line treatment for abdominal pain in patients with irritable bowel syndrome (IBS)(7).</div><div style="background-color: white; font-family: "times new roman";"><br />
Menthol, the cooling natural product of peppermint, according to the study conducted by Yale University School of Medicine, is widely used for the relief of acute and inflammatory pain in sports injuries, arthritis, and other painful conditions, through activating the methol-induced sensation of cooling(8).<br />
Dr. Shen YH and Dr. Nahas R. said," Peppermint oil alleviates IBS symptoms, including abdominal pain" and "several complementary and alternative therapies can be recommended as part of an evidence-based approach to the treatment of IBS; these might provide patients with satisfactory relief and improve the therapeutic alliance"(9).</div><div style="background-color: white; font-family: "times new roman";"><br />
In the 76-year-old woman whose pain had been resistant to standard therapies, application of neat peppermint oil showed to immediately improve her pain with persistence for 4-6 hours after application of the oil(10).<br />
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Taking all together, People with Chronic Pain due to a<span style="background-color: white; font-family: "times new roman";">utosomal recessive polycystic kidney disease</span> should drink the smoothie as much as they can, depending on digestive and liver toleration.<br /><br />
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Back to Kyle J. Norton's Home page <a href="http://kylejnorton.blogspot.ca/">http://kylejnorton.blogspot.ca</a><br />
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<div><b>Kyle J. Norton, all right reserved.</b></div><div>Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.</div><div>Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post</div><div>Nominated for shorty award over last 4 years</div><div>Some articles have been used as references in medical research, such as the international journal Pharma and Bio science, ISSN 0975-6299.</div>
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References<br />
(1) Randomized double-blind crossover study of the efficacy of a tart cherry juice blend in treatment of osteoarthritis (OA) of the knee by Schumacher HR1, Pullman-Mooar S, Gupta SR, Dinnella JE, Kim R, McHugh MP.(<a href="http://www.ncbi.nlm.nih.gov/pubmed/23727631">PubMed</a>)<br />
(2) Cherry juice targets antioxidant potential and pain relief by Kuehl KS1.(<a href="http://www.ncbi.nlm.nih.gov/pubmed/23075558">PubMed</a>)<br />
(3) Efficacy of tart cherry juice in reducing muscle pain during running: a randomized controlled trial by Kuehl KS1, Perrier ET, Elliot DL, Chesnutt JC.(<a href="http://www.ncbi.nlm.nih.gov/pubmed/20459662">PubMed</a>)<br />
(4) The effect of mefenamic acid and ginger on pain relief in primary dysmenorrhea: a randomized clinical trial by Shirvani MA1, Motahari-Tabari N, Alipour A.(<a href="http://www.ncbi.nlm.nih.gov/pubmed/25399316">PubMed</a>)<br />
(5) Effect of Zingiber officinale R. rhizomes (ginger) on pain relief in primary dysmenorrhea: a placebo randomized trial by Rahnama P1, Montazeri A, Huseini HF, Kianbakht S, Naseri M.(<a href="http://www.ncbi.nlm.nih.gov/pubmed/22781186">PubMed</a>)<br />
(6) Ginger Therapy for Osteoarthritis: A Typical Case by Therkleson T1.(<a href="http://www.ncbi.nlm.nih.gov/pubmed/24476702">PubMed</a>)<br />
(7) Treatment of abdominal pain in irritable bowel syndrome by Vanuytsel T1, Tack JF, Boeckxstaens GE.(<a href="http://www.ncbi.nlm.nih.gov/pubmed/24845149">PubMed</a>)<br />
(8) TRPM8 is the principal mediator of menthol-induced analgesia of acute and inflammatory pain by Liu B1, Fan L, Balakrishna S, Sui A, Morris JB, Jordt SE.(<a href="http://www.ncbi.nlm.nih.gov/pubmed/23820004">PubMed</a>)<br />
(9) Complementary and alternative medicine for treatment of irritable bowel syndrome by Shen YH1, Nahas R.(<a href="http://www.ncbi.nlm.nih.gov/pubmed/19221071">PubMed</a>)<br />
(10) A novel treatment of postherpetic neuralgia using peppermint oil by Davies SJ1, Harding LM, Baranowski AP.(<a href="http://www.ncbi.nlm.nih.gov/pubmed/12048423">PubMed</a>)<br />
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Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-4422378433944737036.post-26476440619913205872022-09-11T06:51:00.012-07:002022-09-11T06:51:59.529-07:00Phytochemical Carotenoids Block the Onset of Colorectal Cancer in Patients with DICER1 rs3742330 GenotypeancerCancer is a class of diseases associated with irregular cell growth in the tissue of organs.<br /><br /><br />The colon-rectum formed as a part of the digestive system is involved in the absorption of water from the small bowel contents and breaking down of certain materials in the feces into substances which of them to be reabsorbed and reused by the body.<br /><br />Colorectal cancer is cancer located in the colon or rectum caused by the alternation of cell DNA. Most cases of colorectal cancer begin in the cells on the surface of inner ling tissue in either the colon or rectum, before multiplying to form a tumor.<br /><br /><br />Colorectal cancer is relatively very common and slowly growing and progressing cancer.<br />The disease is also the third most commonly diagnosed cancer in developed countries, including the US and Canada.<br /><br />According to the statistics provided by the American Cancer Society, in the US,<br />101,420 new cases of colon cancer and 44,180 new cases of rectal cancer will be diagnosed in 2019.<br /><br />Additionally, colorectal cancer will also cause the death of 51,020 Americans in 2019.<br /><br /><br />Overall, the lifetime risk of colorectal cancer developing is 1 in 22 (4.49%) in men and 1 in 24 (4.15%) in women. <br /><br /><br />Besides adenocarcinomas, the common type of colorectal cancer originated in epithelium tissues and squamous cells that make up the bowel lining together with the gland cells, other types of colorectal tumors include* Carcinoid<br />Carcinoid is an unusual type of slow-growth neuroendocrine tumor in the hormone-producing tissue in the digestive system. the condition may look benign but can spread to other parts of the body as they grow<br /><br />* Leiomyosarcomas<br />Leiomyosarcomas are a rare and resistant type of colorectal cancer and are generally not very responsive to chemotherapy or radiation. They are a malignant abnormal mass of tissue of smooth muscles of the colon, comprising between 5–10% of soft tissue sarcomas.<br /><br />* Lymphomas<br />Bowel lymphomas are rare and more likely to start in the rectum rather in the colon. Many patients with lymphomas are diagnosed in the late stage and already spread to other organs.<br /><br />* Melanomas<br />Melanomas are rare malignant tumors of cells that produce dark pigment. This type of bowel cancer usually originates from somewhere else and then spread to the bowel.<br /><br />Carotenoids is a class of mainly yellow, orange, or red fat-soluble pigments, including lycopene and carotene, found abundantly in ripe tomato, pumpkins, carrots, corn, and daffodils.<br /><br />On finding a potential compound for the treatment of colorectal cancer, researchers investigated whether dietary lutein/zeaxanthin, the major compounds found in carotenoid intake affect colorectal cancer risk in patients with a DICER1 rs3742330 polymorphism.<br /><br />The experiment included 923 colorectal cancer patients and 1,846 controls based on eligibility criteria, that answered the semiquantitative food frequency questionnaire and the DICER1 rs3742330 genotype.<br /><br />Based on the returned questionnaires differentiation, the highest quartile of lutein/zeaxanthin consumption was inversely associated with colorectal cancer risk.<br /><br /><br />In genotype analysis, patients who carry the G allele (AG + GG) showed a significantly reduced colorectal cancer incidence compared to that AA carriers.<br />Furthermore, patients with G allele (AG + GG) along with high lutein/zeaxanthin consumption were markedly associated with a decreased colorectal cancer risk, particularly in rectal cancer compared to that AA carrier with low lutein/zeaxanthin intakes.<br /><br />The results strongly suggested that carotenoids' major compounds lutein/zeaxanthin has a strong implication on the colorectal cancer risk in patients with the DICER1 rs3742330 genotype.<br /><br />Dr. Kim J, the lead scientist after taking into account co and confounders wrote in the final report, " colorectal cancer risk was related to an interactive effect between dietary lutein/zeaxanthin intake and the DICER1 rs3742330 polymorphism".<br /><br />Taken altogether, carotenoids may be considered a remedy for the prevention and treatment of colorectal cancer, pending the confirmation of the larger sample size and multicenter human study.<br /><br />Intake of carotenoids in the form of supplements should be taken with extreme care to prevent overdose and acute liver toxicity.<br /><br /><br /><b><a href="http://9f55846cqkvfueo9njz33azt0t.hop.clickbank.net/?tid=KYLENORTON">Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight</a><br /><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">How To Get Rid Of Eye Floaters </a><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Contrary To Professional's Prediction, Floaters </a>C<a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">an Be </a><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Cured Naturally </a><br /><br />Ovarian Cysts And PCOS Elimination<br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Holistic System In Existence That Will Show You How To</a><br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Permanently Eliminate All Types of Ovarian Cysts Within 2 Months</a></b><br /><br />Back to Kyle J. Norton Homepage <a href="http://kylejnorton.blogspot.ca/">http://kylejnorton.blogspot.c</a>a<br /><br /><br />Author Biography<br />Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)<br />Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.<br />Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post<br />Nominated for shorty award over last 4 years<br />Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.<br /><br />Sources<br />(1) Plasma and dietary carotenoids and vitamins A, C and E and risk of colon and rectal cancer in the European Prospective Investigation into Cancer and Nutrition by Leenders M1, Leufkens AM, Siersema PD, van Duijnhoven FJ, Vrieling A, Hulshof PJ, van Gils CH, Overvad K, Roswall N, Kyrø C, Boutron-Ruault MC, Fagerhazzi G, Cadeau C, Kühn T, Johnson T, Boeing H, Aleksandrova K, Trichopoulou A, Klinaki E, Androulidaki A, Palli D, Grioni S, Sacerdote C, Tumino R, Panico S, Bakker MF, Skeie G, Weiderpass E, Jakszyn P, Barricarte A, María Huerta J, Molina-Montes E, Argüelles M, Johansson I, Ljuslinder I, Key TJ, Bradbury KE, Khaw KT, Wareham NJ, Ferrari P, Duarte-Salles T, Jenab M, Gunter MJ, Vergnaud AC, Wark PA, Bueno-de-Mesquita HB. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/24771392">PubMed</a>)<br />(2) Antiproliferative effects of carotenoids extracted from Chlorella ellipsoidea and Chlorella vulgaris on human colon cancer cells by Cha KH1, Koo SY, Lee DU. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/18942838">PubMed</a>)<br /><br />Rectal cancer<br />(1) (1) Plasma and dietary carotenoids and vitamins A, C and E and risk of colon and rectal cancer in the European Prospective Investigation into Cancer and Nutrition by Leenders M1, Leufkens AM, Siersema PD, van Duijnhoven FJ, Vrieling A, Hulshof PJ, van Gils CH, Overvad K, Roswall N, Kyrø C, Boutron-Ruault MC, Fagerhazzi G, Cadeau C, Kühn T, Johnson T, Boeing H, Aleksandrova K, Trichopoulou A, Klinaki E, Androulidaki A, Palli D, Grioni S, Sacerdote C, Tumino R, Panico S, Bakker MF, Skeie G, Weiderpass E, Jakszyn P, Barricarte A, María Huerta J, Molina-Montes E, Argüelles M, Johansson I, Ljuslinder I, Key TJ, Bradbury KE, Khaw KT, Wareham NJ, Ferrari P, Duarte-Salles T, Jenab M, Gunter MJ, Vergnaud AC, Wark PA, Bueno-de-Mesquita HB. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/24771392">PubMed</a>)<br />(2) Dietary Lutein Plus Zeaxanthin Intake and DICER1 rs3742330 A > G Polymorphism Relative to Colorectal Cancer Risk by Kim J1, Lee J1, Oh JH2, Chang HJ2, Sohn DK2, Kwon O3, Shin A4, Kim J. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/30833603">PubMed</a>)<br />(3) Bowel (Colorectal ) Cancer by <a href="https://kylejnorton.blogspot.com/2013/10/bowel-colorectal-cancer.html">Kyle J. Norton</a>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-4422378433944737036.post-84120671358991523382022-09-04T08:06:00.002-07:002022-09-04T08:06:07.494-07:00#Healthyfood #Tomato, the Natural and Potential Anti-Inflammatory Remedy, Researchers SayInflammation is a natural response by the immune system to protect the body against the invasion of stimuli or foreign pathogens.<br /><br />In other words, the white blood cells on the first line of defense of the immune system after sensing the danger of an infection in the body through a message from the brain stimulate the production of the palette to cover the site of injury or damage and inflammatory cytokines to kill off all pathogens before they can cause harm to the body.<br /><br />Most cases of infection are stopped at the acute phase. The wound or injury is slowly recovered.<br /><br />However, in severe cases, particularly in people with a weakened immune system, the inflammatory progression cannot be stopped due to the inability of the immune system to destroy all invaders, leading to low-grade chronic inflammation.<br /><br />Diseases associated with low-grade inflammation include diabetes and cardiovascular.<br /><br />Believe it or not, worldwide, 3 of 5 death are results from chronic inflammatory diseases like stroke, chronic respiratory diseases, heart disorders, cancer, obesity, and diabetes.<br /><br /><br />In the US, chronic inflammatory diseases affect more than 50 million Americans each year.<br /><br /><br />Dr. Roma Pahwa in the classification of chronic inflammation wrote, "Chronic inflammation is also referred to as slow, long-term inflammation lasting for prolonged periods of several months to years. Generally, the extent and effects of chronic inflammation vary with the cause of the injury and the ability of the body to repair and overcome the damage".<br /><br /><br />And, "(The causes of chronic inflammation are) Failure of eliminating the agent causing acute inflammation, ..., Exposure to a low level of a particular irritant or foreign materials,...An autoimmune disorder,... Recurrent episodes of acute inflammation,... Inflammatory and biochemical inducers"<br /><br /><br />Tomato is red, edible fruit, genus Solanum, and belongs to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose<br />and often in the greenhouse.<br /><br />On finding a potential compound for the treatment of inflammatory diseases researchers examined the effect of tomato ketchup extracts and bioactive from tomato ketchup on human monocytes and vascular endothelial cells (HUVEC).<br /><br />HUVEC selected for the study were pre-treated for 1 h with either individual bioactive (7.5 µM lycopene, 1.4 µM α-tocopherol, or 55 µM ascorbic acid) or a combination of these three compounds, or with the hydrophilic or lipophilic tomato ketchup extracts or with the two extracts combined.<br /><br />According to the tested assays, tomato ketchup extracts significantly reduced gene expression and pro-inflammatory cytokines TNF-α and IL-8 in HUVEC after inducing inflammation.<br /><br />Furthermore, levels of anti-inflammatory release were increased observed by the expression of anti-inflammatory cytokine IL-10.<br /><br /><br />The effects were correlated with the reduction of IL-8 production in the presence of the test compounds and extracts.<br />In other words, lycopene found in tomato extract is one of the major bioactive compounds that induce the anti-inflammatory effect, and α-tocopherol and ascorbic acid appeared to strengthen the anti-inflammatory effect of lycopene.<br /><br /><br />In order to obtain more information about tomato anti-inflammatory activity, researchers analyzed the potential protective effects of phytochemicals in tomatoes on inflammation. <br /><br />According to the nitric oxide (NO) assay, tomato extract exhibited an anti-inflammatory effect by inhibiting the NO production in LPS-stimulated RAW264 macrophages.<br />Levels of pro-inflammatory cytokines were significantly decreased after the injection of tomatoes.<br /><br /><br /><br />The efficacy of tomatoes was attributed to the bioactive compound RF52 in the inhibition of the production of these proinflammatory mediators.<br /><br />Dr. Kim YI, the lead scientist said, "These results suggest that RF52 from tomatoes may have the potential to suppress inflammation by inhibiting the production of NO or proinflammatory cytokines during the interaction between adipocytes and macrophages".<br /><br /><br />Taken altogether, tomatoes may be considered functional food for the prevention and treatment of inflammatory diseases, pending the confirmation of the larger sample size and multicenter human study.<br /><br /><br /><b><a href="http://9f55846cqkvfueo9njz33azt0t.hop.clickbank.net/?tid=KYLENORTON">Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight</a><br /><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">How To Get Rid Of Eye Floaters </a><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Contrary To Professional's Prediction, Floaters </a>C<a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">an Be </a><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Cured Naturally </a><br /><br />Ovarian Cysts And PCOS Elimination<br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Holistic System In Existence That Will Show You How To</a><br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Permanently Eliminate All Types of Ovarian Cysts Within 2 Months</a><br /><br />Back to Kyle J. Norton Homepage <a href="http://kylejnorton.blogspot.ca/">http://kylejnorton.blogspot.c</a>a</b><br /><br /><br />Author Biography<br />Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)<br />Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.<br />Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post<br />Nominated for shorty award over last 4 years<br />Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.<br /><br />Sources<br />(1) Protection against chemotaxis in the anti-inflammatory effect of bioactives from tomato ketchup by Hazewindus M1, Haenen GR1, Weseler AR1, Bast A. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/25551565">PubMed</a>)<br />(2) Tomato extract suppresses the production of proinflammatory mediators induced by interaction between adipocytes and macrophages by Kim YI1, Mohri S, Hirai S, Lin S, Goto T, Ohyane C, Sakamoto T, Takahashi H, Shibata D, Takahashi N, Kawada T. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/25603813">PubMed)</a><br />(3) Chronic Inflammation by Roma Pahwa; Ishwarlal Jialal. (<a href="https://www.ncbi.nlm.nih.gov/books/NBK493173/">NCBI)</a>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-4422378433944737036.post-55998506070603830072022-08-21T16:56:00.009-07:002022-08-21T16:56:57.138-07:00Cooked Tomato's Lycopene Protects Protein, Lipid and Cell Damage Against Oxidative Stress in Human Studies<br /><br /> Oxidative stress is a condition characterized by overexpression of free radicals in the body.<br /><br />In other words, oxidative stress is a result of the imbalance of the ratio of free radicals and antioxidants caused by abundant free radicals and low levels of antioxidant enzymes produced by the body.<br /><br />A free radical is an unstable atom with a single electron on the outermost ring. Given its nature, free radicals readily donate or intercept an electron from another atom, leading to a chain of the free radical cascade that cannot be stopped until all single electron is paired or inhibited by antioxidants.<br /><br />The antioxidant is a stable atom with a function to inhibit oxidation, and comes either from dietary sources or produced by the body.<br /><br />In contrast to general belief, free radical is also needed in moderated amounts for the function of the heart muscle to pump blood such as NO for vasodilation and increasing blood flow.<br /><br />According to studies, in cancer, oxidative stress has been found to induce cytotoxicity used in chemotherapy for the treatment of cancer by killing cancer cells.<br /><br />However, in a healthy person, oxidative stress is harmful because it not only induces cells lipid and protein oxidation but also causes the change of cell DNA, leading to diseases associated with oxidative stress including cancer, diabetes, and cardiovascular disease.<br /><br />Ozone, certain pesticides, cleaners, cigarette smoke, radiation, and pollution are some of the risk factors associated with the increased risk of oxidative stress.<br /><br />Based on the oxidative stress theory of aging oxidative stress, oxidative stress is also the main culprit contributing to aging in humans.<br /><br /> Dr. Ilaria Liguori, the lead scientist said, "Aging is a process characterized by the progressive loss of tissue and organ function. The oxidative stress theory of aging is based on the hypothesis that age-associated functional losses are due to the accumulation of RONS-induced damages".<br /><br /><br />Tomato is red, edible fruit, genus Solanum, belongs to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose<br />and often in the greenhouse.<br /><br /><br />With an aim to find a potential compound for the treatment of diseases associated with oxidative stress researchers examined the efficacy of lycopene a carotenoid commonly found in tomatoes and tomato products.<br /><br /><br />A total of 23 healthy postmenopausal women, 50-60 years old, provided blood samples at baseline and following a one-month lycopene-depletion period according to the St. Michael's Hospital, Toronto, ON, Canada. PARTICIPANTS AND STUDY DESIGN.<br />Compared to the blood sample before and after experiment samples, a one-month lycopene-depletion period diet showed a significantly decreased antioxidant profile including serum lycopene, lutein/zeaxanthin, and glutathione peroxidase (GPx).<div><br />Furthermore, the diet also depressed levels of antioxidant enzymes superoxide dismutase (SOD), and catalase (CAT), significantly in the participants while increasing levels of lipid and protein oxidation.<br />In other words, a tomato restrictive diet increased the risk of diseases associated with oxidative stress in postmenopausal women due to the increase of ROS and depletion of antioxidants in the tissues.<br /><br /><br />In order to reveal more information about tomato's effect on oxidative stress, researchers conducted a study to determine whether lycopene would act as an antioxidant to decrease oxidative stress parameters.<br />The study included a total of 60 postmenopausal women, 50-60 years old, following a 1-month washout without lycopene consumption,.<br /><br /><br />After a month, the participants were randomly divided into groups with 15 members each consuming either : (1) regular tomato juice, (2) lycopene-rich tomato juice, (3) tomato Lyc-O-Mato lycopene capsules, or (4) placebo capsules, twice daily for total lycopene intakes of 30, 70, 30, and 0 mg/day respectively for 4 months.<br /><br />According to the tested assays, for 4 months significantly increased serum lycopene compared to placebo.<br /><br />Moreover, the total serum antioxidant capacity (TAC) and decreasing lipid and protein peroxidation were found to increase substantially in the groups treated with consumed juice or lycopene capsules compared to the placebo group.<br /><br />Taken altogether, tomatoes and their major bioactive compound lycopene may be considered remedies for the prevention and treatment of diseases associated with oxidative stress, pending the confirmation of the larger sample size and multicenter human study.<br /><br /><br />Intake of lycopene in the form of supplement should be taken with extreme care to prevent overdose and acute liver toxicity.<br /><b><br /><a href="http://9f55846cqkvfueo9njz33azt0t.hop.clickbank.net/?tid=KYLENORTON">Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight</a><br /><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">How To Get Rid Of Eye Floaters </a><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Contrary To Professional's Prediction, Floaters </a>C<a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">an Be </a><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Cured Naturally </a><br /><br />Ovarian Cysts And PCOS Elimination<br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Holistic System In Existence That Will Show You How To</a><br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Permanently Eliminate All Types of Ovarian Cysts Within 2 Months</a><br /><br />Back to Kyle J. Norton Homepage <a href="http://kylejnorton.blogspot.ca/">http://kylejnorton.blogspot.c</a>a<br /></b><br /><br />Author Biography<br />Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)<br />Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.<br />Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post<br />Nominated for shorty award over last 4 years<br />Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.<br /><br />Sources<br />(1) Dietary restriction of lycopene for a period of one month resulted in significantly increased biomarkers of oxidative stress and bone resorption in postmenopausalwomen by Mackinnon ES1, Rao AV, Rao LG. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/21365167">PubMed</a>)<br />(2) Supplementation with the antioxidant lycopene significantly decreases oxidative stress parameters and the bone resorption marker N-telopeptide of type I collagen in postmenopausal women by Mackinnon ES1, Rao AV, Josse RG, Rao LG. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/20552330">PubMed)</a><br />(3) Oxidative stress, aging, and diseases by Ilaria Liguori,1 Gennaro Russo,1 Francesco Curcio,1 Giulia Bulli,1 Luisa Aran,1David Della-Morte,2,3 Gaetano Gargiulo,4 Gianluca Testa,1,5 Francesco Cacciatore,1,6Domenico Bonaduce,1 and Pasquale Abete. (<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927356/">PMC</a>)</div>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-4422378433944737036.post-47138501544791046232022-07-23T07:31:00.000-07:002022-07-23T07:31:28.013-07:00Honey, the Best Natural Remedy for Chronic Otitis Externa With No Side EffectsIn seeking natural therapy with no side effects, scientists may have found a herbal medicine for the prevention and treatment of acute otitis externa, according to studies.<div><br />Acute otitis externa is a condition characterized by the inflammation of the ear canal. Most cases of acute cute otitis externa are associated with the infection by Pseudomonas aeruginosa and Staphylococcus aureus due to improper cleaning.<br /><br />However, people with seborrhoeic dermatitis caused by inflammation of greasy areas of the skin can also lead to infection of the ears.<br /><br />The most common symptoms of acute otitis include itching, canal edema, canal erythema, and otorrhea.<br /><br /><br /><br />Most cases of acute otitis externa are healed within days with proper ear drops. However, there is a rare case where the disease may take weeks or months to recover.<br /><br /><br />Chronic otitis externa shares the common symptoms of the acute form, accompanied by water retention and severe ear pain, and temporary loss of hearing, due to building up thick and dry skin that can build up inside the ear canal, leading to narrowing of the ear canal.<br /><br />Untreated chronic otitis externa can cause deafness.<br /><br />Besides sharing the risk factors with the acute form, otitis externa can also be caused by infection due to the long-term use of hearing aids and earplugs. <br /><br /><br />Unlike the acute form, most cases of otitis externa are treated with steroid drops in addition to antibiotics accompanied by oral intake of pain medications such as ibuprofen.<br /><br /><br />Generally, oral antibiotics are not recommended, however, if the infection has spread beyond the ear canal, oral antibiotics may be applied.<br /><br /><br />According to the statistics, otitis externa affects 1–3% of people in America a year and 95% of people's complaints of the condition are acute.<br /><br /><br />Honey, the rich golden liquid is a miraculous product made by bees using nectar from flowers.<br /><br />The liquid is considered one of the healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.<br /><br />The finding of a natural ingredient for the treatment of eczematous external otitis, scientists investigated the antibacterial potential of medical honey eardrops as a treatment of eczematous external otitis.<br /><br /><br />15 patients diagnosed with recurrent eczematous external otitis were selected and treated with medical honey eardrops for 2 weeks. <br /><br />Honey treatment resulted in less discomfort and itching and decreased signs of eczema with no side effects, according to assays.<br /><br /><br />Although honey eardrops showed a strong in vitro inhibitory activity against all tested strains, it did not eradicate Staphylococcus aureus infection.<br /><br />Honey eardrops also reduced the visual analog scale of ear complaints, and a score of eczema, and increased the eradication of bacterial infection. Most patients in the study, are satisfied with the use of honey eardrops for the treatment of their eczematous external otitis.<br /><br /><br />Dr. Henatsch D, the lead scientist, after taking into account co and confounders said, "The results of this preliminary study indicate a possible role of honey eardrops in eczematous ear disease".<br /><br />Taken altogether, honey may be considered a functional remedy for the treatment of eczematous external otitis, pending the confirmation of a larger sample size and multicenter human study.<br /><br /><br /><b><a href="http://9f55846cqkvfueo9njz33azt0t.hop.clickbank.net/?tid=KYLENORTON">Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight</a><br /><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">How To Get Rid Of Eye Floaters </a><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Contrary To Professionals Prediction, Floaters </a>C<a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">an Be </a><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Cured Naturally </a><br /><br />Ovarian Cysts And PCOS Elimination<br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Holistic System In Existence That Will Show You How To</a><br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Permanently Eliminate All Types of Ovarian Cysts Within 2 Months</a><br /><br />Back to Kyle J. Norton Homepage <a href="http://kylejnorton.blogspot.ca/">http://kylejnorton.blogspot.c</a>a</b><br /><br /><br />Author Biography<br />Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)<br />Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.<br />Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post<br />Nominated for shorty award over last 4 years<br />Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.<br /><br />References<br />(1) Treatment of Recurrent Eczematous External Otitis with Honey Eardrops: A Proof-of-Concept Study by Henatsch D1, Nabuurs CH1, van de Goor RM1, Wolffs PF2, Stokroos RJ. <a href="https://www.ncbi.nlm.nih.gov/pubmed/28695767">(PubMed)</a><br />(2) Alternative Treatments for Atopic Dermatitis: An Update by Shi K1, Lio PA. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/30511123">PubMed</a>)<br />(2) Acute Otitis Externa: An Update by PAUL SCHAEFER, MD, PhD, and REGINALD F. BAUGH, MD. (<a href="https://www.aafp.org/afp/2012/1201/p1055.html">AAFP</a>)</div>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-4422378433944737036.post-56110244267510068132022-07-09T08:28:00.011-07:002022-07-09T08:30:31.424-07:00Honey, the Best Natural Treatment For High Blood Pressure with No Side Effects, Scientists SayIn seeking natural therapy with no side effects, scientists may have a herbal remedy for normalizing blood pressure, according to studies.<div><br />Hypertension is a chronic condition caused by abnormally high blood pressure.<br /><br />High blood pressure is a condition of a cluster of metabolic syndrome associated with the increased risk of heart disease and stroke.<br /><br />Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood.<br /><br />In high blood pressure individuals, due to the elevated blood pressure in your arteries, the heart has to work harder than normal to pump blood through the blood vessels.<br /><br />In low blood pressure individuals, the reduced blood pressure in the arteries drops can cause the heart to pump blood at a slower rate than normal.<br /><br /><br />According to the standard guidelines, the levels of blood pressure is normal if it is more than 120 over 80 and less than 140 over 90 (120/80-140/90).<br /><br /><br />People with blood pressure lower than 120/80 are considered normal without being accompanied by symptoms of light-head or dizziness.<br /><br />According to the statistics provided by the CDC, in the U.S. 29% or 100 million adults have hypertension during 2015–2016 and hypertension prevalence increased with age and was 33.2% among those aged 40–59 and 63.1% among those aged 60 and over.<br /><br /><br />Honey, the rich golden liquid is a miraculous product made by bees using nectar from flowers.<br /><br />The liquid is considered one of the healthy food for replacing the use of white sugar and artificial sweetener by many people.<br /><br />Researchers in the course of finding a natural ingredient for the treatment of high blood pressure investigated the safety and effect of intrapulmonary administration (by inhalation) of 60 % honey solution, 10% dextrose, or distilled water in normal or diabetic subjects.<br /><br />Twenty-four healthy subjects, 16 patients with type 1 diabetes mellitus and six patients with hypertension were selected to participate in the study.<br /><br /><br />Twelve healthy subjects were subjected to distilling water inhalation for 10 min, and after one week they received inhalation of honey solution (60% wt/v) for 10 min. Another 12 healthy subjects received inhalation of 10% dextrose for 10 min.<br /><br />Honey treatment showed a mild reduction of blood pressure compared to no change in another group.<br /><br />From a time perspective, systolic and diastolic blood pressure was reduced by honey inhalation in hypertensive patients at 60 and 120 min.<br /><br /><br />After taking into account co and confounders, researchers said, "honey inhalation was safe and effective in reducing...elevated blood pressure in hypertensive patients".<br /><br />Moreover, in order to obtain more information on honey antihypertensive activity, researchers investigated the aqueous extract obtained from the mixture of the fresh leaf of Persea Americana, stems, and a fresh leaf of Cymbopogon citrus, fruits of Citrus medica, and honey on ethanol and sucrose-induced hypertension in rats.<br /><br /><br />Rats included in the study were divided into eight groups of 6 rats each and daily treated for 5 weeks. The control group received distilled water (1 mL/kg) while rats of groups 2, 3, and 4 received ethanol 40 degrees (3 g/kg/day), 10% sucrose as drinking water, and the two substances respectively.<br /><br />The remaining groups received additional sucrose and ethanol, the aqueous extract (50, 100, and 150 mg/kg) or nifedipine (10 mg/kg) respectively.<br /><br /><br />Group treated with ethanol and sucrose showed a significantly (p < 0.001) increased blood pressure and heart rate compared to distilled water-treated rats.<br /><br /><br />Chronic treatment of ethanol and sucrose also exerted significantly decreased the activities of antioxidant enzymes produced by the host, observed by the levels of superoxide dismutase (SOD) and catalase (CAT) and elevated levels of oxidative stress observed by the stress marker malondialdehyde (MDA) levels.<br /><br />However, administration of the aqueous extract or nifedipine prevented all changes caused by chronic ethanol and sucrose, including the hemodynamic, biochemical, oxidative, and histological impairments.<br /><br /><br />The finding clearly suggested that aqueous extract including honey possesses antihypertensive activity by the improvement of biochemical and oxidative status, through its antioxidant property.<br /><br />Taken altogether, honey used alone or combined with other herbs may be considered anti-hypertension functional remedies with no side effects, pending the confirmation of a large sample size and multicenter human study.<br /><br /><br /><br /><b><a href="http://9f55846cqkvfueo9njz33azt0t.hop.clickbank.net/?tid=KYLENORTON">Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight</a><br /><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">How To Get Rid Of Eye Floaters </a><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Contrary To Professional's Prediction, Floaters </a>C<a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">an Be </a><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Cured Naturally </a><br /><br />Ovarian Cysts And PCOS Elimination<br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Holistic System In Existence That Will Show You How-To</a><br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Permanently Eliminate All Types of Ovarian Cysts Within 2 Months</a><br /><br />Back to Kyle J. Norton Homepage <a href="http://kylejnorton.blogspot.ca/">http://kylejnorton.blogspot.c</a>a</b><br /><br /><br />Author Biography<br />Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)<br />Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.<br />Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post<br />Nominated for shorty award over last 4 years<br />Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.<br /><br />References<br />(1) Intrapulmonary administration of natural honey solution, hyperosmolar dextrose or hypoosmolar distill water to normal individuals and to patients with type-2 diabetes mellitus or hypertension: their effects on blood glucose level, plasma insulin and C-peptide, blood pressure and peaked expiratory flow rate by Al-Waili N1. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/12911866">PubMed</a>)<br />(2) Antihypertensive potential of the aqueous extract which combine leaf of Persea americana Mill. (Lauraceae), stems and leaf of Cymbopogon citratus (D.C) Stapf. (Poaceae), fruits of Citrus medical L. (Rutaceae) as well as honey in ethanol and sucrose experimental model by Dzeufiet PD1, Mogueo A, Bilanda DC, Aboubakar BF, Tédong L, Dimo T, Kamtchouing P. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/25519078">PubMed)</a></div>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-4422378433944737036.post-11705834350481482442022-07-03T11:00:00.004-07:002022-07-03T11:00:34.707-07:00Tomato Apoptoses Liver Cancer Better Than of Doxorubicin and Camptothecin in Vitro<br /><br /> Cancer is a class of diseases caused by cells growing disorderly and uncontrollably in our bodies.<br /><br />Liver cancer is a chronic medical condition associated with irregular cell growth in the liver tissues.<br /><br /><br />The liver is the largest internal organ that only filters out blood from the intestine before passing them to other parts of the body, but also produces bile to aid digestion, build strong cell walls and vitamin D and steroid hormones.<br /><br /><br />The liver joined with the kidney and skin is considered 3 detoxed organs in the human.<br /><br /><br />Most common liver cancers are* Hepatocellular carcinoma, is a most common liver cancer accounting, accounting for 75 percent of all cases caused by the DNA alternation of hepatocytes, predominant liver cells.<br /><br />Epidemiologically, primarily hepatocellular carcinoma has been found to metastasize to the pancreas, intestines, and stomach.<br /><br /><br />* Cholangiocarcinoma, also known as bile duct cancer, is caused by abnormal cell growth in the small, tube-like bile ducts in the liver, accounting to 10 to 20% of all liver cancer cases.<br /><br /><br />Out of many prevalent factors that cause the onset of liver cancer, some researchers suggested that the promotion of a high-fat diet over the past few decades may have a strong impact to increase the risk of liver cancer.<br /><br /><br />Dr. Qiu-Ye Lan, the lead scientist wrote, "Healthy dietary patterns may prevent many chronic diseases and is emphasized by 2015 US dietary guideline, but it remains unclear which dietary patterns may be a benefit to prevention of primary liver cancer (PLC)"<br /><br /><br />And, "Our findings suggest that the UPDP (an urban prudent dietary pattern (UPDP)) and TCDP (traditional Cantonese dietary pattern (TCDP) )were associated with lower, whereas the MPFP with the higher, risk of PLC".<br /><br /><br />Tomato is red, edible fruit, genus Solanum, belongings to family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose<br />and often in the greenhouse.<br /><br />In the urgency to discover healthy foods for the treatment of liver cancer, researchers examined the effect of the tomato antiproliferative activities against human colon (HT29) and liver (HepG2) cancer cells.<br /><br />Application of the tetrasaccharide tomato glycoalkaloid alpha-tomatine, the trisaccharide beta(1)-tomatine, the disaccharide gamma-tomatine, the monosaccharide delta-tomatine, and their common aglycon tomatidine showed better inhibition of liver cancer cell compared to the tested colon cell line.<br /><br />Additionally, alpha-tomatine isolated from tomato at a concentration of 1 microg/mL demonstrated a greater effect against liver carcinoma cells compared to those of anticancer drugs doxorubicin and camptothecin<br /><br />Furthermore, alpha-tomatine also inhibited normal human liver HeLa (Chang) cells without inducing any side effects.<br /><br />Also in vitro, according to the tested assays,<br />* Alpha-tomatine isolated from green tomatoes induced liver cancer cells death compared to little inhibition of the cells by the three low-tomatine red tomato extracts.<br /><br /><br />* Alpha-Tomatine from tomato also was highly effective in inhibiting all of the liver cell lines, compared to little cell inhibition of ehydrotomatine, tomatidenol, and tomatidine.<br /><br /><br /><br />Collectively, the results not only showed the susceptibility to destruction varies with the nature of the alkaloid and plant extract but also how phytochemicals in plants worked synergistically in cancer inhibition.<br /><br />Dr. Friedman M, the lead scientist said, "These findings extend related observations on the anticarcinogenic potential of glycoalkaloids and suggest that consumers may benefit by eating not only high-lycopene red tomatoes but also green tomatoes containing glycoalkaloids".<br /><br /><br />Taken altogether, tomato processed with a high amount of lycopene may be considered a dietary supplement for the prevention and treatment of liver cancer, pending to large sample size and multicenter human study.<br /><br />Intake of lycopene in the form of supplement should be taken with extreme care to prevent overdose and acute liver toxicity.<br /><b><br /><a href="http://9f55846cqkvfueo9njz33azt0t.hop.clickbank.net/?tid=KYLENORTON">Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight</a><br /><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">How To Get Rid Of Eye Floaters </a><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Contrary To Professionals' Prediction, Floaters </a>C<a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">an Be </a><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Cured Naturally </a><br /><br />Ovarian Cysts And PCOS Elimination<br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Holistic System In Existence That Will Show You How-To</a><br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Permanently Eliminate All Types of Ovarian Cysts Within 2 Months</a><br /><br />Back to Kyle J. Norton Homepage <a href="http://kylejnorton.blogspot.ca/">http://kylejnorton.blogspot.c</a>a</b><br /><br /><br />Author Biography<br />Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)<br />Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.<br />Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post<br />Nominated for shorty award over last 4 years<br />Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.<br /><br />Sources<br />(1) Tomatine-containing green tomato extracts inhibit the growth of human breast, colon, liver, and stomach cancer cells by Friedman M1, Levin CE, Lee SU, Kim HJ, Lee IS, Byun JO, Kozukue N. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/19514731">PubMed</a>)<br />(2) Glycoalkaloids and metabolites inhibit the growth of human colon (HT29) and liver(HepG2) cancer cells by Lee KR1, Kozukue N, Han JS, Park JH, Chang EY, Baek EJ, Chang JS, Friedman M. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/15137822">PubMed</a>)<br />(3) Dietary patterns and primary liver cancer in Chinese adults: a case-control study by Qiu-Ye Lan,1 Gong-Cheng Liao,1 Rui-Fen Zhou,1 Pei-Yan Chen,1 Xiao-Yan Wang,1Min-Shan Chen,2 Yu-Ming Chen,1 and Hui-Lian Zhu. (<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021235/">PubMed)</a>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-4422378433944737036.post-48561489623260178142022-06-26T07:27:00.004-07:002022-06-26T07:27:18.710-07:00Cabbage Protects the Cells Integrity Against Oxidative StressOxidative stress is a condition caused by an imbalance of the ratio of free radicals and antioxidants in the body.<br />In other words, oxidative stress is either caused by overexpression of free radicals or depletion of antioxidant enzymes in the body.<br /><br />Some researchers suggested that oxidative stress may also arise due to the chain reaction of free radicals in which free radicals donate or intercept an electron from other stable molecules.<br /><br />Long-term oxidative stress present in the body can cause protein and lipid damage and alternation of cell DNA, leading to the onset of chronic diseases, including cardiovascular disease, diabetes, and cancer.<br /><br />More precisely, exogenous factors, such as cigarette smoke, and endogenous factors, such as the oxidative burst from activated macrophages are some of the factors involved in the risk of oxidative stress.<br /><br /><br />Free radicals are highly reactive molecules with an unpaired electron on the outer ring of the atom.<br /><br />Due to its nature to become stable, free radicals readily donate or steal an electron from other molecules, leading to the chain of domino's effect that can not be stopped until either the electrons are paired or inhibited by antioxidants.<div><br />This chain of reaction is the cause of oxidative stress, a condition associated with either overexpression of free radicals or depletion of antioxidant enzymes produced by the host organs.<br /><br />Antioxidants are stable atom that plays a critical role in protecting the body against the attack of free radicals.<br /><br />In other words, antioxidants inhibited the onset of free radicals before they can cause a chain reaction in facilitating protein, lipid, and cell damage.<br /><br />Antioxidants can either be produced by the liver or intake from dietary sources. Under normal conditions, antioxidant enzymes produced by the body in a healthy individual are good enough to counter the bombardment of free radical attacks.<br /><br />Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem with a crowded mass of leaves, usually green but in some varieties, it may be red or purplish.<br /><br />On findings of a natural wholefood for the prevention and treatment of diseases associated with oxidative stress, researchers investigated the effects of red cabbage anthocyanin (RCA)-enriched extract on H₂O₂ expression on HepG2 cells.<br /><br />According to chemical analysis, all derivatives of cyanidin (268 ± 2 μg/mg) found in RCA, mainly with 19% nonacylated, 51% monoacylated, and 31% diacylated structures with ferulic, sinapic, p-coumaric, and caffeic acids exerted antioxidant activity against the oxidative stress induced by the injection of H₂O₂.<br /><br /><br />Furthermore, the application of RCA extracts markedly ameliorated cell apoptosis and improved viability.<br /><br /><br />Moreover, in another study, cabbage extract protected against H2O2-induced cell death and did not elicit any cytotoxic effects by suppressing ROS production and increasing the expression of antioxidant proteins (SOD-1, catalase, and GPx) produced by the host.<br /><br /><br />In oxidative stress-exposed H9c2 cells, the protective effects of cabbage extract also inhibited apoptotic responses and activation of MAPK proteins (ERK1/2, JNK, and p-38) involved in the resistance of apoptosis by preserving mitochondrial functions.<br /><br />Based on the results, researchers wrote, "cabbage extract protects against oxidative stress and suggests that it can be used as an alternative therapeutic strategy to prevent the oxidative stress in the heart".<br /><br />Taken altogether, cabbage may be used as a functional food for the prevention and treatment of diseases associated with oxidative stress, pending the confirmation of the larger sample size and multicenter human study.<br /><br /><br /><b><a href="http://9f55846cqkvfueo9njz33azt0t.hop.clickbank.net/?tid=KYLENORTON">Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight</a><br /><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">How To Get Rid Of Eye Floaters </a><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Contrary To Professionals' Prediction, Floaters </a>C<a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">an Be </a><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Cured Naturally </a><br /><br />Ovarian Cysts And PCOS Elimination<br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Holistic System In Existence That Will Show You How-To</a><br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Permanently Eliminate All Types of Ovarian Cysts Within 2 Months</a><br /><br />Back to Kyle J. Norton Homepage <a href="http://kylejnorton.blogspot.ca/">http://kylejnorton.blogspot.c</a>a<br /></b><br /><br />Author Biography<br />Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)<br />Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.<br />Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post<br />Nominated for shorty award over last 4 years<br />Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.<br /><br />Sources<br />(1) Characterization of Purified Red Cabbage Anthocyanins: Improvement in HPLC Separation and Protective Effect against H₂O₂-Induced Oxidative Stress in HepG2 Cells by Fang S1, Lin F2, Qu D3, Liang X4, Wang L. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/30602654">PubMed</a>)<br />(2) Cabbage (Brassica oleracea var. capitata) Protects against H2O2-Induced Oxidative Stress by Preventing Mitochondrial Dysfunction in H9c2 Cardiomyoblasts by Yang DK. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/30158990">PubMed</a>)</div>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-4422378433944737036.post-21319879779734819092022-06-19T16:53:00.000-07:002022-06-19T16:53:02.362-07:00Broccoli Inhibits the Onset of Oxidative Stress<br /><br /> Oxidative stress is a medical condition characterized by the imbalance of the ratio of free radicals and antioxidant enzymes produced by the host tissue.<br /><br /><br />Free radicals are highly reactive molecules with an unpaired electron on the outer ring of the atom.<br />Due to its nature to become stable, free radicals readily donate or steal an electron from other molecules, leading to the chain of domino's effect that can not be stopped until either the electrons are paired or inhibited by antioxidants.<br /><br />This chain of reaction is the cause of oxidative stress, a condition associated with either overexpression of free radicals or depletion of antioxidant enzymes produced by the host organs.<br /><br />In some cases, this reaction also is caused long-term accumulation of toxic substances in the body, such as lead, cadmium, mercury, and arsenic.<br /><br /><br />Antioxidants are stable atom that plays a critical role in protecting the body against the attack of free radicals.<br /><br />In other words, antioxidants inhibited the onset of free radicals before they can cause a chain reaction in facilitating protein, lipid, and cell damage.<br /><br />Antioxidants can either be produced by the liver or intake from dietary sources. Under normal conditions, antioxidant enzymes produced by the body in a healthy individual are good enough to counter the bombardment of free radical attacks.<br /><br /><br /><br />There is no single cause of oxidative stress. Some researchers suggested that a number of factors can facilitate the onset of oxidative stress, including cigarette smoke, and oxidative burst from activated macrophages, particularly, the free radicals chain reaction.<br /><br />Sadly, a prolonged period of oxidative stress present in the human body can cause oxidative damage to biomolecules, (lipids, proteins, DNA) and the death of healthy cells through cytotoxicity.<br /><br />Certain chronic diseases are found to be associated with oxidative stress, including atherosclerosis, cancer, diabetes, rheumatoid arthritis, post-ischemic perfusion injury, myocardial infarction, cardiovascular diseases, chronic inflammation, and stroke.<br /><br /><br />Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae. The vegetable has large flower heads, usually green in color and the mass of flower heads is surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.<br /><br /><br />In finding a potential plant that processes anti-oxidative activity researchers examined the efficacy of sulforaphane found in broccoli in protecting alcohol-induced hepatic injury in vivo.<br /><br />The study included selected male C57BL/6 mice which were orally administrated with broccoli sprout extract (BSE) containing sulforaphane [7.6, 25.2, and 50.4 mg/kg of body weight (bw)] once a day for 14 days.<br /><br /><br /><br />On the 13th day, mice were challenged with alcohol (5 g/kg of bw) every 12 h for 3 times, which increased malondialdehyde (MDA) levels (4.44 ± 1.24 nmol/mg of protein, p < 0.01) of oxidative stress in the liver.<br /><br />According to the results of the experiment, the administration of low-, medium-, and high-dose BSE markedly reversed the decrease in antioxidant capacity.<br /><br /><br />More precisely, BSE increased the levels of antioxidant enzymes such as glutathione (GSH), superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), and glutathione S-transferase (GST) in the liver, compared to control.<br /><br /><br />The efficacy in protecting the liver from oxidative stress was attributed to the activation of phase 2 enzymes via nuclear erythroid-2-related factor 2 (Nrf2).<br /><br />Most importantly, BSE also significantly attenuated the levels of the endoplasmic reticulum (ER)-stress-specific proteins, a defense system that protects cells from ER stress such as glucose-regulated protein 78 (GRP78), activating transcription factor 6, and protein kinase RNA (PKR)-like ER kinase (PERK),<br /><br /><br />Collectively, researchers said, "These results indicate that BSE protects the liver against alcohol challenge via upregulating antioxidant capacity and downregulating ER stress".<br /><br /><br />Taken altogether, broccoli may be considered a functional food for the prevention and treatment of diseases associated with oxidative stress, pending the confirmation of the larger sample size and multicenter human study.<br /><br /><br /><b><a href="http://9f55846cqkvfueo9njz33azt0t.hop.clickbank.net/?tid=KYLENORTON">Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight</a><br /><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">How To Get Rid Of Eye Floaters </a><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Contrary To Professionals' Prediction, Floaters </a>C<a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">an Be </a><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Cured Naturally </a><br /><br />Ovarian Cysts And PCOS Elimination<br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Holistic System In Existence That Will Show You How-To</a><br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Permanently Eliminate All Types of Ovarian Cysts Within 2 Months</a></b><br /><br />Back to Kyle J. Norton Homepage <a href="http://kylejnorton.blogspot.ca/">http://kylejnorton.blogspot.c</a>a<br /><br /><br />Author Biography<br />Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)<br />Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.<br />Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post<br />Nominated for shorty award over last 4 years<br />Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.<br /><br />Sources<br />(1) Broccoli Sprout Extract Alleviates Alcohol-Induced Oxidative Stress and Endoplasmic Reticulum Stress in C57BL/6 Mice by Lei P1, Zhao W1, Pang B1, Yang X1, Li BL2,3, Ren M4, Shan YJ. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/29730925">PubMed)</a>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-4422378433944737036.post-52418966752935778242022-06-11T17:27:00.007-07:002022-06-11T17:27:32.775-07:00Cruciferous vegetables, The Potential Neuro-Protective Healthy FoodsNeuroprotection is a process to preserve the neuronal structure and/or function against the death or gradual death of neurons, including the use of medicines and herbs.<br /><br />In other words, neuroprotection protects the neuronal integrity against the reduction in the rate of neuronal loss over time inducing neurological disease, including neurodegenerative disease.<br />Neurological diseases are the medical conditions of brain disorders. Anything that involves structural, biochemical, or electrical abnormalities in the brain, spinal cord, or other nerves, including brain damage is considered neuron disease.<br /><br />Neurodegenerative disease is the class of condition associated with the progressive loss of neurons that occurred mostly in older adults, including dementia. The most common dementia in the US is Alzheimer`s disease (AD).<br /><br />Alzheimer's disease is an irreversible, progressive brain disorder caused by the slowly lost of neuron in the brain that affects the memory and thinking skills and, eventually, the ability to carry out the simplest tasks as the disease progress into the advanced stage.<br /><br />According to the statistic, dementia affects over 47.5 million people worldwide, approximately 58 percent are living in low and middle-income countries.<br /><br />Believe it or not, 5.8 million Americans of all ages are living with Alzheimer's dementia in 2019, and two-thirds of people with Alzheimer's disease are women.<br /><br />Conventionally, as of today, there is no cure for dementia. Treatment of dementia is focusing improving dementia symptoms and slowing down the progression of the disease.<br /><br /><br />Cruciferous vegetables are a group of vegetables, belongings of the family Brassicaceae (also called Cruciferae) with many genera, and species, and cultivated all over the world in suitable climates for commercial profits, including cauliflower, cabbage, kale, garden cress, bok choy, broccoli, Brussels sprouts, and green leafy vegetables.<br /><br />On finding a potential compound for the treatment of neurological diseases, researchers examined cruciferous vegetable neuroprotective activity.<br /><br />According to the dietary information,<br />* SFN, a potent bioactive compound found in the veggies upregulated the nuclear factor erythroid 2-related factor 2 (Nrf2) antioxidant response element (ARE) genetic pathway by increasing the antioxidant enzymes produced by the host.<br /><br />* SFN was found to protect the nervous system from many diseases and toxins in a few small human trials.<br /><br />* Furthermore, according to the preclinical data, SFN protected the nervous system through multiple mechanisms, reduced the risk of many diseases and the burden of symptoms in existing conditions.<br /><br />In other words, SFN processed protective effects in a multitude of neurological diseases and toxin exposures.<br /><br />Based on the evidence, researchers said, "SFN is a promising neuroprotective phytochemical which needs further human trials to evaluate its efficacy in preventing and decreasing the burden of many neurological diseases".<br /><br /><br />Taken altogether, cruciferous vegetables may be considered neuroprotective functional foods, pending the confirmation of the larger sample size and multicenter human study.<br /><br /><b><br /><a href="http://9f55846cqkvfueo9njz33azt0t.hop.clickbank.net/?tid=KYLENORTON">Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight</a><br /><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">How To Get Rid Of Eye Floaters </a><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Contrary To Professional's Prediction, Floaters </a>C<a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">an Be </a><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Cured Naturally </a><br /><br />Ovarian Cysts And PCOS Elimination<br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Holistic System In Existence That Will Show You. How-To</a><br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Permanently Eliminate All Types of Ovarian Cysts Within 2 Months</a></b><br /><br />Back to Kyle J. Norton Homepage <a href="http://kylejnorton.blogspot.ca/">http://kylejnorton.blogspot.c</a>a<br /><br /><br />Author Biography<br />Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)<br />Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.<br />Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post<br />Nominated for shorty award over last 4 years<br />Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.<br /><br />Sources<br />(1) The neuroprotective mechanisms and effects of sulforaphane by Klomparens EA1, Ding Y. <a href="https://www.ncbi.nlm.nih.gov/pubmed/31334360">(PubMed</a>)Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-4422378433944737036.post-40389109184753395242022-06-05T08:42:00.004-07:002022-06-05T08:42:19.921-07:00Healthy Food #Broccoli' SFN Protects the Lung Against Lung Cancer in Vitro<br /><br /> The lung-formed part of the circulatory system plays an essential and unique role in taking oxygen to the blood and exhaling carbon dioxide from the blood.<div><br />Additionally, the lung also processes other abilities in protecting our body against disease, including<br />* By balancing the pH levels, the lung protects the body against the accumulation of too much carbon dioxide. High levels of carbon dioxide are known to induce acidity in the body.<br /><br />* By removing small blood clots the lung protects the body against the forming air embolisms.<br /><br />* The airflow produced by the lung also helps us to speak.<br /><br />* The lung also protects against the infection through the secretion of immunoglobulin A.<br /><br />Any part of the lung injury can reduce lung function, leading to either obstructive or restrictive lung diseases or mixed lung disease, depending on a person's breathing.<br /><br /><br />Lung cancer is a chronic medical condition characterized by abnormal growth of the cells in the lung tissue.<br /><br />The most common form of primary lung cancer is derived from epithelial cells.<br /><br />The exact cause of lung cancer is not identified. However, epidemiologically, smoking, second smoke, exposure to certain chemicals, family history, people who have lung disease, and excessive drinking are some prevalent factors associated with lung cancer development.<br /><br />According to the statistics provided by the American cancer society, lung cancer accounts for 14% of all new cancers diagnosed in the US. In 2018, there were about 234,030 new cases of lung cancer (121,680 in men and 112,350 in women). Lung cancer also causes the death of 83,550 men and 70,500 women in the same year.<br /><br />Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae. The veggie has large flower heads, usually green in color with a mass of flower heads surrounded by leaves and evolved from a wild cabbage plant from the continent of Europe.<br /><br />With an aim to find a natural food for the prevention and treatment of cancer, researchers examined the chemopreventive role of SFN through the inhibition of histone deacetylase (HDAC) associated with the regulation of DNA expression, in two different lung cancer cells by in vitro and in vivo mouse models.<br /><br />According to the experimental results from A549 and H1299 lung cancer cells were treated with SFN for 48h,<br /><br />* SFN inhibited HDAC activity and increased the levels of acetylated histones H3 and H4 involved in cell death in all two lung cancer cells.<br /><br /><br />* Furthermore, SFN induced cancer cells apoptosis, increased the accumulation of cells at G0/G1 and G2/M, and arrested cells at the S phase.<br /><br /><br />* Moreover, SFN also suppressed lung cancer growth in a xenograft mouse model in vivo.<br /><br />Based on the results, researchers wrote, " the chemopreventive effect of SFN is associated with inhibition of HDAC activity, thereby attenuating lung cancer growth. Therefore, these findings suggest that SFN may be a therapeutic agent for lung cancer through the inhibition of HDAC".<br /><br />Taken altogether, broccoli processed abundantly SFN may be considered supplements for the prevention of lung cancer, pending to the confirmation of the larger sample size and multicenter human study.<br /><br />Intake of SFN in the form of supplements should be taken with extreme care to prevent overdose and acute liver toxicity.<br /><br /><b><a href="http://9f55846cqkvfueo9njz33azt0t.hop.clickbank.net/?tid=KYLENORTON">Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight</a><br /><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">How To Get Rid Of Eye Floaters </a><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Contrary To Professional's Prediction, Floaters </a>C<a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">an Be </a><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Cured Naturally </a><br /><br />Ovarian Cysts And PCOS Elimination<br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Holistic System In Existence That Will Show You. How-To</a><br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Permanently Eliminate All Types of Ovarian Cysts Within 2 Months</a><br /><br />Back to Kyle J. Norton Homepage <a href="http://kylejnorton.blogspot.ca/">http://kylejnorton.blogspot.c</a>a<br /></b><br /><br />Author Biography<br />Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)<br />Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.<br />Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post<br />Nominated for shorty award over last 4 years<br />Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.<br /><br />Sources<br />(1) Sulforaphane suppresses in vitro and in vivo lung tumorigenesis through downregulation of HDAC activity by Jiang LL1, Zhou SJ1, Zhang XM2, Chen HQ2, Liu W. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/26898427">PubMed)</a></div>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-4422378433944737036.post-51767208835238888032022-05-29T07:23:00.002-07:002022-05-29T07:23:10.538-07:00Honey, the Herbal Remedy Which Suppresses OsteoarthritisIn seeking natural therapy with no side effects, scientists may have a herbal remedy for the prevention and treatment of osteoarthritis, according to studies.<div><br />Osteoarthritis (OA) is a common chronic inflammatory joint disease characterized by the breaking down of joint cartilage and the underlying bone.<br /><br />Genetic preposition, overweight, obesity, injury, and overuse of the joints are the most common risk factor associated with the onset of the disease.<br /><br /><br />Occupation with the repetitive movements of the joint is most affected by the disease.<br /><br />Interestingly, osteoarthritis symptoms can come and go throughout the day and vary from person to person. The weather change has been one of the most complaints that trigger the symptoms of OA in the elderly.<br /><br /><br />Most common symptoms, according to epidemiological studies include joint pain, tenderness, and lack of flexibility and stiffness.<br /><br /><br />Some osteoporotic patients may also experience symptoms of grating sensation and bone spurs.<br /><br /><br />If you experience some of the above symptoms, you may have osteoarthritis.<br /><br />Some researchers suggested that obesity may be one of the major risk factors besides the occupation with the repetitive movement of osteoarthritis in the Western world.<br /><br />Dr. Lauren K. King, the lead scientist in the investigation of obesity & osteoarthritis, wrote, "The most significant impact of obesity on the musculoskeletal system is associated with osteoarthritis (OA), a disabling degenerative joint disorder characterized by pain, decreased mobility, and negative impact on quality of life".<br /><br /><br /><br />And, "Obesity is associated with the incidence and progression of OA of both weight-bearing and non-weight-bearing joints, to rate of joint replacements as well as operative complications".<br /><br /><br />The finding strongly indicated the risk of osteoarthritis is increased by many folds in the obese population, compared to those with a healthy weight.<br /><br />Honey, the rich golden liquid is a miraculous product made by bees using nectar from flowers.<br /><br />The liquid is considered healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.<br /><br />In the concerns of widespread osteoarthritis (OA), a chronic degenerative joint disease, researchers investigated chrysin, a natural flavonoid extracted from honey and propolis anti-inflammatory effects.<br /><br /><br />The study included human OA chondrocytes pretreated with chrysin (1, 5, 10 μM) for 2 h and subsequently stimulated with IL-1β, an inflammatory cytokine for 24 h.<br /><br />Injection of chrysin exerted a strong inhibition activity against the degradation of aggrecan and collagen-II.<br /><br />Chrysin significantly inhibited the IL-1β-induced production of inflammatory cytokines such as degradation of c of NO and PGE2; expression of COX-2, iNOS.<br /><br /><br />Furthermore, chrysin also reduced the expression of matrixes such as MMP-1, MMP-3, MMP-13, and enzymes ADAMTS-4, and ADAMTS-5 associated with the progression and destruction of joints in early osteoarthritis.<br /><br />In the depth analysis researchers also found that chrysin dramatically blocked IL-1β-stimulated IκB-α degradation in the activation of protein NF-κB-induced production of proinflammatory cytokines.<br /><br /><br />The results suggested that chrysin inhibits the progression of OA through several mechanisms, including enzymes and proteins involving the destruction of joint tissues.<br /><br />Taken altogether, honey processed with a bioactive compound chrysin may be considered a functional remedy for the prevention and treatment of OA, with no side effects, pending the confirmation of a larger sample size and multicenter human study.<br /><br /><br /><br /><b><a href="http://9f55846cqkvfueo9njz33azt0t.hop.clickbank.net/?tid=KYLENORTON">Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight</a><br /><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">How To Get Rid Of Eye Floaters </a><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Contrary To Professionals' Prediction, Floaters </a>C<a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">an Be </a><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Cured Naturally </a><br /><br />Ovarian Cysts And PCOS Elimination<br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Holistic System In Existence That Will Show You How-To</a><br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Permanently Eliminate All Types of Ovarian Cysts Within 2 Months</a><br /></b><br />Back to Kyle J. Norton Homepage <a href="http://kylejnorton.blogspot.ca/">http://kylejnorton.blogspot.c</a>a<br /><br /><br />Author Biography<br />Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)<br />Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.<br />Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post<br />Nominated for shorty award over last 4 years<br />Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.<br /><br />References<br />(1) Chrysin Attenuates IL-1β-Induced Expression of Inflammatory Mediators by Suppressing NF-κB in Human Osteoarthritis Chondrocytes by Zheng W1, Tao Z1, Cai L1, Chen C1, Zhang C1, Wang Q1, Ying X1, Hu W1, Chen H2. (<a href="https://www.ncbi.nlm.nih.gov/pubmed/28364187">PubMed)</a><div style="background-color: #fb5e53; color: #666666; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 13px;"><div><div><div>(2) Obesity & osteoarthritis by Lauren K. King,* Lyn March,** and Ananthila Anandacoomarasamy. (<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788203/" style="color: #2198a6; text-decoration-line: none;" target="_blank">PMC</a>)</div></div></div></div></div>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-4422378433944737036.post-82455157563478591002022-05-23T08:06:00.009-07:002022-05-23T08:06:33.476-07:00Healthy Food Broccoli Processes Anti-Hypercholesterolemic PropertyThe liver is the largest internal organ found in the human which plays an essential role in filtering the blood from the digestive system before passing them to other parts of the body.<div><br />The liver also produces cholesterol, a waxy substance that aids digestion, builds cell membranes, and produces vitamin D and steroid hormones.<br /><br />Hypercholesterolemia is a condition characterized by abnormally high levels of cholesterol in the bloodstream.<br /><br />In other words, the condition is caused by either overexpression of low-density lipoprotein (LDL) or low levels of high-density lipoprotein (HDL).<br /><br />Cholesterol, a waxy substance produced by the liver or the dietary in moderate amount source plays a critical to aid digestive function in absorbing nutrients, building strong cell membranes, produce steroid hormones and vitamin D. However, excessive amounts in the blood have been found to induce plaque built-up on the arterial wall, leading to heart disease and stroke.<br /><br />Similar to high blood pressure, people with hypercholesterolemia are asymptomatic. Patients with familial hyper cholesterol may experience symptoms of chest pain with activity. xanthomas, and cholesterol deposits around the eyelids.<br /><br />The most common complications associated with uncontrolled hypercholesterolemia are carotid artery disease, coronary heart disease, including angina or heart attack, peripheral artery disease, and stroke.<br /><br />The most common complications associated with uncontrolled hypercholesterolemia are carotid artery disease, coronary heart disease, including angina or heart attack, peripheral artery disease, and stroke.<br /><br />According to the statistics provided by the CDC, hypercholesterolemia is a major risk factor of heart disease, a leading cause of death in the US. In the US, approximately, 71 million American adults (33.5%) have high low-density lipoprotein (LDL), or “bad,” cholesterol, and only 1 out of every 3 adults with high LDL cholesterol has the condition under control.<br /><br />Sadly, only 50% of people with hypercholesterolemia are getting treatment.<br /><br />Out of many risk factors associated with the risk of hypercholesterolemia, some researchers suggested that widespread obesity due to aging may have a strong impact on the increased incidence in the US.<br /><br /><br />Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae. The vegetable has large flower heads, usually green in color and the mass of flower heads is surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.<br /><br /><br />On finding a potential plant that processes anti-high blood cholesterol, researchers examined a diet rich in high glucoraphanin (HG) broccoli that reduces plasma LDL-C.<br /><br />130 volunteers recruited to two independent double-blind, randomly allocated parallel dietary intervention studies, were assigned to consume either 400 g standard broccoli or 400 g HG broccoli per week for 12 weeks. <br /><br />According to the plasma lipids before and after the intervention, <br />* In one study, The HG broccoli diet reduced plasma LDL-C by 7.1% (95% CI: –1.8%, –12.3%, p = 0.011), whereas standard broccoli reduced LDL-C by 1.8% (95% CI +3.9%, –7.5%, ns). In study 2 (93 volunteers)<br /><br />* In another study, the HG broccoli diet resulted in a reduction of 5.1% (95% CI: –2.1%, –8.1%, p = 0.001), whereas standard broccoli reduced LDL-C by 2.5% (95% CI: +0.8%, –5.7%, ns). <br /><br />* When data from the two studies were combined the reduction in LDL-C by the HG broccoli was significantly greater than standard broccoli (p = 0.031).<br /><br /><br />Collectively, researchers said, "Evidence from two independent human studies indicates that consumption of high glucoraphanin broccoli significantly reduces plasma LDL-C".<br /><br />Taken altogether, broccoli may be considered a functional food for the prevention and treatment of hypercholesterolemia, pending the confirmation of the larger sample size and multicenter human study.<br /><br /><br /><b><a href="http://9f55846cqkvfueo9njz33azt0t.hop.clickbank.net/?tid=KYLENORTON">Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight</a><br /><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">How To Get Rid Of Eye Floaters </a><br /><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Contrary To Professional's Prediction, Floaters </a>C<a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">an Be </a><a href="http://593f96ddqd-jz9q3vnoonh1l48.hop.clickbank.net/?tid=MAIN">Cured Naturally </a><br /><br />Ovarian Cysts And PCOS Elimination<br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Holistic System In Existence That Will Show You How-To</a><br /><a href="http://99a5eb8fmaxf8gq40dq743lesm.hop.clickbank.net/?tid=ALOE">Permanently Eliminate All Types of Ovarian Cysts Within 2 Months</a><br /><br />Back to Kyle J. Norton Homepage <a href="http://kylejnorton.blogspot.ca/">http://kylejnorton.blogspot.c</a>a</b><br /><br /><br />Author Biography<br />Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)<br />Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.<br />Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post<br />Nominated for shorty award over last 4 years<br />Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.<br /><br />Sources<br />(1) Diet rich in high glucoraphanin broccoli reduces plasma LDL cholesterol: Evidence from randomised controlled trials by Charlotte N Armah,1 Christos Derdemezis,2 Maria H Traka,1 Jack R Dainty,1 Joanne F Doleman,1 Shikha Saha,1 Wing Leung,1 John F Potter,3 Julie A Lovegrove,2 and Richard F Mithen. (<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692095/">PubMed</a>)</div>Unknownnoreply@blogger.com0