Soy and renal cell carcinoma tumors and metastatic disease

Posted by Chantel M. Contributed by US National Library of Medicine National Institutes of Health

According to the study of `Monitoring sunitinib-induced vascular effects to optimize radiotherapy combined with soy isoflavones in murine xenograft tumor`by Hillman GG, Singh-Gupta V, Al-Bashir AK, Yunker CK, Joiner MC, Sarkar FH, Abrams J, Haacke EM., posted in US National Library of Medicine National Institutes of Health, researchers found that that soy could protect the vasculature of normal tissue from the adverse effects of sunitinib. An antiangiogenic approach that only partially destroys inefficient vessels could potentially increase the efficacy and delivery of cytotoxic therapies and radiotherapy for unresectable primary renal cell carcinoma tumors and metastatic disease.