Saturday, August 24, 2013

Can anti-mullerian hormone predict the diagnosis of polycystic ovary syndrome?

 Posted by Chantel Martiromo, research contributed by PubMed

In a systematic literature review to assess the true accuracy of AMH in the prediction of PCOS and to determine the optimal diagnostic threshold, posted in PubMed, found that t he meta-analysis of the extracted data demonstrated the specificity and sensitivity in diagnosing PCOS in the symptomatic women of 79.4% and 82.8%, respectively, for a cutoff value of AMH of 4.7 ng/mL. The area under the curve was 0.87 (95% confidence interval 0.83-0.92), identical with the area under the curve of 0.87 for the summary receiver-operating characteristic curve involving 10 separate studies.

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