Dietary phytoestrogen intake--lignans and isoflavones--and breast cancer risk (Canada)

Posted by Chantel Martiromo. research contributed by PubMed  

In the study to evaluate whether phytoestrogen intake is associated with reduced breast cancer risk, using a novel phytoestrogen database, posted in PubMed, showed that among all women, lignan intake was associated with a reduced breast cancer risk (Q5 vs. Q1 MVOR: 0.81, 95% CI: 0.65, 0.99); however, following stratification by BMI, this reduction in risk was statistically significant only among overweight (BMI > 25) women. Total phytoestrogen intake was also associated with a risk reduction among overweight women only. Among pre-menopausal women, total phytoestrogen intake was associated with a significant reduction in breast cancer risk among overweight women only (Q5 vs. Q1 MVOR: 0.51, 95% CI: 0.30, 0.87). Among post-menopausal women, no statistically significant association was observed between breast cancer risk and isoflavones or lignans.
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