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Friday, March 25, 2022

Healthy Tomatoes, the Antioxidant Functional Food



Antioxidants are stable atom that plays a critical role in protecting the body against the attack of free radicals.

In other words, antioxidants inhibited the onset of free radicals before they can cause a chain reaction in facilitating protein, lipid, and cell damage.

Antioxidants can either be produced by the liver or intake from dietary sources. Under normal conditions, antioxidant enzymes produced by the body in a healthy individual are good enough to counter the bombardment of free radical attacks.

However, in people with a weakened immune system, intake of dietary sources of antioxidants may be necessary.

There are 3 main types of antioxidants found in nature, including
* Antioxidant enzymes produced by the host, including superoxide dismutase (SOD), glutathione peroxidase, glutathione reductase, and catalases.

* Antioxidants vitamins, that may be injected from dietary sources such as fruits and vegetables, including vitamin A, C, D, and E. Most antioxidant vitamins are considered free radical scavengers that gobble up free radicals before they can induce a cascade of damage.

* Antioxidant Phytochemicals found in the plant including second metabolites.

Antioxidants keep our bodies functioning properly by reducing the risk of diseases associated with oxidative stress.

Dr. Esra Birben, the lead scientist in the evaluation of oxidative stress and antioxidant defense wrote, "Reactive oxygen species (ROS) are produced by living organisms as a result of normal cellular metabolism and environmental factors, such as air pollutants or cigarette smoke. ROS are highly reactive molecules and can damage cell structures such as carbohydrates, nucleic acids, lipids, and proteins and alter their functions. The shift in the balance between oxidants and antioxidants in favor of oxidants is termed “oxidative stress".

And, "Aerobic organisms have integrated antioxidant systems, which include enzymatic and nonenzymatic antioxidants that are usually effective in blocking the harmful effects of ROS. However, in pathological conditions, the antioxidant systems can be overwhelmed. Oxidative stress contributes to many pathological conditions and diseases, including cancer, neurological disorders, atherosclerosis, hypertension, ischemia/perfusion, diabetes, acute respiratory distress syndrome, idiopathic pulmonary fibrosis, chronic obstructive pulmonary disease, and asthma".

In other words, we can say goodbye to the diseases involved in oxidative stress by maintaining the proper ratio of free radicals and antioxidants in the body.


Tomato is red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.

With an aim to find a natural ingredient with the best antioxidant activity, researchers compared the parental line, for antioxidant levels in fresh and hot break fruit, and the bioaccessibility of antioxidants from the puree.

Believe it or not, there are Different found in the concentrations of antioxidants between the wild-type and the genetically modified raw tomatoes.


However, compared to the parent of BM tomatoes, GM tomatoes were found to maintain antioxidant levels to a greater extent in the puree and in vitro digestion model, the levels of antioxidants were showed an increase in the genetically modified samples, according to the bioaccessibility of the analysis of the compounds.


Although researchers found that GM tomatoes processed similar or better antioxidant levels compared to the parent, they do not mention a possibility of toxicity of the genetically modified samples.

In vivo, the antioxidant activity of several types of tomato taken from the Andean valleys was tested on Caenorhabditis Elegans subjected to thermal stress, researchers found the metabolite composition of tomatoes are totally depending on the geographical origin and fruit size.

The antioxidant activity of tomatoes also depends on the phenolic compounds, such as caffeoylquinic acids, ferulic acid-O-hexosides, and rutin which are associated with the fruit size, and geographical origin.

The findings suggested that all tomatoes process different levels of phytochemicals that may affect the antioxidant properties, depending on the size and type.

Taken altogether, tomatoes processed abundantly bioactive compounds may be considered an antioxidant supplement against oxidative stress, pending the confirmation of the larger sample size and multicenter human study.



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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Antioxidant compounds and their bioaccessibility in tomato fruit and puree obtained from a DETIOLATED-1 (DET-1) down-regulated genetically modified genotype by Talens P1, Mora L2, Bramley PM2, Fraser PD. (PubMed)
(2) Hydrophilic antioxidants from Andean tomato landraces assessed by their bioactivities in vitro and in vivo by Di Paola Naranjo RD1, Otaiza S2, Saragusti AC2, Baroni V3, Carranza Adel V2, Peralta IE4, Valle EM5, Carrari F6, Asis R. (PubMed)
(3) Oxidative Stress and Antioxidant Defense by Esra Birben, PhD,1 Umit Murat Sahiner, MD,1 Cansin Sackesen, MD,1 Serpil Erzurum, MD,2and Omer Kalayci, MD. (PMC)

Saturday, March 19, 2022

Healthy Food #Honey, The Remedy MayBe Used for the Prevention and Treatment of Stomach Ulcers, According to Studies

Scientists may have found natural alternative antibiotics for the treatment of stomach ulcers caused by a bacterial infection, some studies found.

A stomach/Gastric ulcer is a condition characterized by the breaking in the tissue lining of the stomach.

Most cases of stomach ulcers are caused by the infection with the Helicobacter pylori bacterium or long-term intake of anti-inflammatory medication.

The most common symptoms of stomach ulcers include a dull pain in the stomach, gastrointestinal discomforts such as nausea or vomiting. bloating, burping, or burning sensation in the chest.


If you are experiencing some of the above symptoms persistently, please check with your doctor to rule out the possibility of a stomach ulcer.
Unless the disease is caused by medication, most stomach ulcers can be treated successfully with the use of antibiotics and medications that reduce the overproduction of stomach acid.


Some researchers suggested that people who are obese are also susceptible to the onset of stomach ulcers due to the following reasons
* Epidemiological findings suggested that obesity is associated with inflammation in the gut, leading to the weakness of gut cells that are prone to ulcer formation.

* Obesity has been found to have an unhealthy ratio of gut bacteria.

* Overexpression gut harmful bacterias increased the risk of toxin accumulation in the lining of the gut.

Honey is a miraculous product made by bees using nectar from flowers.

The rich golden liquid is considered one of the healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.

Researchers on finding a natural compound for the treatment of stomach ulcers investigated the Manuka honey antiulcer activity in gastric rats.

Ethanol-induced gastric ulcers in rats selected for the study were divided into control, ethanol (ulcer), omeprazole, and manuka honey group.

Injection of Manuka honey significantly decreased the ulcer index, completely protected the mucosa from lesions, and preserved gastric mucosal glycoprotein through the increased expression of gastric mucosal levels of nitric oxide (NO) in the inhibition of leukocyte adherence to the endothelium, and antioxidant enzymes glutathione (GSH), glutathione peroxidase (GPx), superoxide dismutase (SOD).

Furthermore, Manuka honey also decreased gastric mucosal MDA, the oxidative stress marker, and proinflammatory expression in the stomach caused by the injection of ethanol (ulcer), omeprazole.

Dr. the lead scientist wrote, "Manuka honey likely exerted its antiulcer, effect by keeping enzymatic (GPx and SOD) and nonenzymatic (GSH and NO) antioxidants as well as inflammatory cytokines (TNF-α, IL-1β, and IL-6) in a reduced form, inhibited lipid peroxidation (MDA), and preserved mucous glycoproteins levels".

The findings clearly suggested Manuka honey inhibited stomach ulcers by modulating oxidative stress, proinflammatory cytokines, and antioxidant expression.

In order to reveal more information about the honey antiulcer activity, researchers evaluated the use of Manuka honey in the treatment of acetic acid-induced chronic gastric ulcers in rats.

The study included rats treated with three different concentrations of honey. Treatment with manuka honey was found to significantly reduce the ulcer index and maintain the glycoprotein content.


Manuka injection also reduced the mucosal myeloperoxidase activity, lipid peroxidation (MDA), and the inflammatory cytokines (TNF-α, IL-1β, and IL-6) as compared to the untreated control group.
Honey-treated groups showed a significant increase in enzymatic (GPx and SOD) and nonenzymatic (GSH) antioxidants besides levels of the anti-inflammatory cytokine IL-10, similar to that of the previous study.

More importantly, manuka honey-treated animals not only normalized cell cycle distribution but also significantly lowered apoptosis in gastric mucosa.

The results indicated that manuka honey is effective for the treatment of chronic ulcers through many mechanisms.

Taken altogether, Manuka honey may be considered a functioning remedy for the prevention and combined with primary medicine for the treatment of stomach ulcers with no side effects.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.

Sources
(1) Antioxidant, Anti-inflammatory, and Antiulcer Potential of Manuka Honey against Gastric Ulcer in Rats by Saad B. Almasaudi, 1 Nagla A. El-Shitany, 2 , 3 Aymn T. Abbas, 4 , 5 Umama A. Abdel-dayem, 6Soad S. Ali, 7 Soad K. Al Jaouni, 8 and Steve Harakeh. (PMC)
(2) Manuka Honey Exerts Antioxidant and Anti-Inflammatory Activities That Promote Healing of Acetic Acid-Induced Gastric Ulcer in Rats by Almasaudi SB1, Abbas AT2, Al-Hindi RR1, El-Shitany NA3, Abdel-Dayem UA4, Ali SS5, Saleh RM6, Al Jaouni SK7, Kamal MA8, Harakeh SM. (PubMed)
(3) Association of peptic ulcer disease with obesity, nutritional components, and blood parameters in the Korean population by Jihye Kim, Keun Ho Kim, and Bum Ju Lee. (PMC)

Saturday, March 12, 2022

Cabbage Protects the Liver Against Injury

The liver is the largest internal organ in the human body, played an essential role in filtering blood from the intestine before passing them to other parts of the body.

The organ also produced cholesterol, a waxy substance that is needed to aid digestion and build strong cell membranes, production of steroid hormones and vitamins.

Liver injury may be a result caused by physical impact or penetrating trauma. In some cases, liver injury can also be induced by toxicity, leading to acute liver injury.

Liver injury can be mild or severe. In a mild case, liver injury can recover itself. However, in severe cases. surgery to stop the bleeding and remove the part of the injury may be necessary.

According to the statistics, liver injury has been found to constitute 5% of all traumas, making it the most common abdominal injury.


Other most common symptoms associated with liver injury are shocks due to severe bleeding inducing a rapid heart rate, rapid breathing, and cold, clammy, pale or bluish skin.

In some cases, blood accumulated in the abdomen may irritate the abdominal tissue, leading to symptoms of abdominal pain and swelling, and tenderness.

The severity of a liver injury can be diagnosed by computed tomography (CT) or ultrasonography.

Depending on the size of the wound, most cases of liver injury are healed by themselves. However, in severe cases, hospitalization may be necessary if the bleeding does not stop.

The most common cause of liver injury is an overdose of medicine which has been found to be the number 1 factor.


Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem with a crowded mass of leaves, usually green but in some varieties, it may be red or purplish.

On findings a natural whole for the improvement of liver diseases, researchers examined the hepatoprotective properties of the essential oil (EO) from white cabbage.

On acute carbon tetrachloride (CT)-induced liver damage,
* Bocfal EO contained organic polysulphides (OPSs), such as dimethyl trisulphide (DMTS) 65.43 ± 4.92% and dimethyl disulfidefood (DMDS) 19.29 ± 2.16% as major constituents.

* Bocfal EO and DMTS were found to be potent TBARS, a byproduct of lipid peroxidation inhibitors with IC50 values of 0.51 and 3 mg/L, respectively.


* Bocfal EO demonstrated better hepatoprotective properties than did DADS (p < 0.05), although both slightly affected the hepatic parenchyma per se.

Based on the findings, researchers said, "The antioxidant properties of Bocfal EO and DMTS may be the mechanism of hepatoprotective action; the parenchymal disturbances by Bocfal EO or DADS alone may be related to the high doses used".

Taken altogether, cabbage process anti liver injury, pending the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Evaluation of antioxidant and hepatoprotective effects of white cabbage essential oil by Morales-López J1, Centeno-Álvarez M2, Nieto-Camacho A3, López MG4, Pérez-Hernández E5, Pérez-Hernández N1, Fernández-Martínez E. (PubMed).