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".....Utilizing Traditional Chinese Medicine in Tonifying Energy flow to the Reproductive System Channels In Men and Women for Natural Conception, including Couple Who were diagnosed with Unexplained causes of Infertility...." Chantel M.

Monday, October 21, 2019

Tomatoes Kill Bacterial Staphylococcus Aureus Against the Onset of Pneumonia

Pneumonia is a medical condition associated with the infection of the lung. In adults, the most common causes of pneumonia are a bacterial infection such as Staphylococcus aureus.

Viruses or fungi also have been found to induce the onset of the disease.

Most common symptoms of pneumonia are persistent coughing with phlegm (mucus) fever, sweating, chills and chest pain. However, depending on the types of pathogens that cause the infection.

In severe cases, pneumonia is life-threatening. Some patients at this stage also experience persistently shortness of breath due to severe inflammation in the air sacs of the lungs.

According to epidemiological studies, most cases of pneumonia are acquired from either hospitals and communities caused by people who have the disease.

Some researchers suggested people who have weakened such as elderly or immature immune systems such as babies and underage children are more prone to the disease.


Dr. Sanjay Sethi at the University at Buffalo SUNY wrote, "Pneumonia is an infection of the lungs. Pneumonia in people whose immune system is weakened or impaired (for example, by AIDS, cancer, organ transplantation, or the use of certain drugs) is often caused by different organisms than those that cause pneumonia in healthy people".

In other words, people who are treated by chemotherapy drugs due to cancer or immune suppressants, and disease associated with immunity are susceptible to pneumonia developing.

Most cases of pneumonia are treated with antibiotics. Depending on the condition, treatment may include medicine for reduced coughing, pain and fever with an aim to improve patients' quality of life.

If you are taking certain types of antibiotics for the treatment of pneumonia, please make sure you know all the side effects for preventive measures.

Tomato is red, edible fruit, genus Solanum, belonging to family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.

On finding a potential ingredient for the treatment of Staphylococcus aureus pneumonia, researchers examined the effect of naringenin found abundantly in tomato.

In the Staphylococcus aureus pneumonia model, naringenin protected the lung cells integrity and viability by inhibiting the production of α-toxin.

Where α-toxin is an essential virulence factor found in patients with Staphylococcus aureus pneumonia.

Furthermore, at the 16 μg/ml of naringenin, treatment organisms showed reduced expression of α-toxin significantly compared to the untreated group.

Moreover, in vivo, a mouse model of S. aureus pneumonia treated with naringenin demonstrated a significant effect in attenuating symptoms of lung injury and inflammation against infection.

In other words, naringenin acted as a natural antibiotic in preventing the overexpression of α-toxin produced by Staphylococcus aureus through its antibacterial activity.


Based on the findings, Dr. Zhang Y, the lead scientist after taking into account co and confounders wrote in the final report, "These results suggest that naringenin is a promising agent for the treatment of S. aureus infection".

Taken altogether, tomatoes may be considered supplements for the prevention and treatment of Staphylococcus aureus pneumonia, pending to the confirmation of the larger sample size and multicenter human study.

Intake of naringenin in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Inhibition of α-toxin production by subinhibitory concentrations of naringenin controls Staphylococcus aureus pneumonia by Zhang Y1, Wang JF, Dong J, Wei JY, Wang YN, Dai XH, Wang X, Luo MJ, Tan W, Deng XM, Niu XD. (PubMed)
(2) Pneumonia in Immunocompromised People By Sanjay Sethi , MD, University at Buffalo SUNY. (MSD Manual)

Manuka Honey, The Anti Antioxidants Functional Sweety

Honey may be the next pharmaceutical target to identify the single ingredient medicine for the treatment of diseases associated with oxidative stress, some scientists suggested.

Oxidative stress is a result of an imbalance of the ratio of free radicals and antioxidants in the body.

Free radicals are highly reactive molecules with an unpaired electron on the outer ring of the atom.
Due to its nature to become stable, free radicals readily to donate or steal an electron from other molecules, leading to the chain of domino's effect that can not be stopped until either the electrons are paired or inhibited by antioxidants.

This chain of reaction is the cause of oxidative stress, a condition is associated with either overexpression of free radicals or depletion of antioxidant enzymes produced by the host organs.

Overexpression of free radicals is known to cause damage in contributing to the etiology of many chronic health problems such as cardiovascular and inflammatory disease, cataracts, and cancer.
Antioxidants, on the other hand, are stable molecules with a unique function in the inhibition of oxidation.

Dr. V. Lobo, the lead author in the study "Free radicals, antioxidants, and functional foods: Impact on human health" wrote, " A balance between free radicals and antioxidants is necessary for proper physiological function. If free radicals overwhelm the body's ability to regulate them, a condition known as oxidative stress ensues", and

"Free radicals thus adversely alter lipids, proteins, and DNA and trigger a number of human diseases. Hence the application of an external source of antioxidants can assist in coping with this oxidative stress. Synthetic antioxidants such as butylated hydroxytoluene and butylated hydroxyanisole have recently been reported to be dangerous for human health".

These results suggested that regardless of the causes of the overexpression of free radicals, intake of dietary sources of antioxidants from a supplement, herbs, fruits, and vegetables can be beneficial in restoring the healthy ratio of free radicals and antioxidants and preventing the onset of oxidative stress.

Honey is the miraculous product made by bees using nectar from flowers.

The rich golden liquid It is considered one of healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.

In order to understand the honey antioxidant activity which has been under intensified study by the science community, a joint study led by the researchers conducted was conducted in an animal model.

Ethanol-induced gastric ulcers in rats were randomly assigned to control, ethanol (ulcer), omeprazole, and manuka honey.

Honey treated rats displayed a clinically significant decrease of the ulcer index by completely protected the mucosa from lesions and preserved gastric mucosal glycoprotein.

Application of manuka honey also decreased gastric mucosal MDA, the marker of oxidative stress and plasma TNF-α, IL-1β, and IL-6 concentrations, the set of proinflammatory cytokines produced by the ethanol injection.

The results were attributed to the manuka honey in stimulating the production of antioxidant enzymes which were suppressed by the injection of ethanol in the tested rats

The finding suggested that manuka honey exerted a strong antioxidant activity by balancing the ratio of free radicals and antioxidant enzymes in the treatment group.

In other words, manuka honey inhibited the oxidative stress caused by overexpression of free radicals in the initiation of the onset of the ulcer.

Further differentiation to reaffirm the effects of manuka honey in the inhibition of gastric ulcer in the rat model, researchers examined three different concentrations of honey applied to the tested rats.

During the experiment, researchers found that all 3 different concentration display a strong effect in It reducing the mucosal myeloperoxidase activity, lipid peroxidation (MDA), and the inflammatory cytokines (TNF-α, IL-1β, and IL-6) compared to the untreated control group.

In other words, manuka honey protects the rat stomach by inhibiting the overexpression of free radical and pro-inflammatory cytokines in inducing oxidative stress.

Application manuka honey also showed a significant increase in enzymatic (GPx and SOD) and nonenzymatic (GSH) antioxidants which were reduced due to ulcer and levels of the anti-inflammatory cytokine IL-10.

The Flow cytometry assay also indicated that treatment of rats with manuka honey has normalized cell cycle distribution and significantly lowered apoptosis in gastric mucosa.

The information collected strong to support the use of manuka honey for the treatment of chronic ulcer and preservation of mucosal glycoproteins.


Dr. Almasaudi SB wrote in the final report, "Its (manuka honey) effects are due to its antioxidant and anti-inflammatory properties that resulted in a significant reduction of the gastric mucosal MDA, TNF-α, IL-1β, and IL-6 and caused an elevation in IL-10 levels.


Taken altogether, there is no doubt that manuka honey high in antioxidants can be considered a functional food for the prevention and combined with the primary medicine for the treatment of diseases associated with oxidative stress.





Natural Medicine for Fattstudyver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Antioxidant, Anti-inflammatory, and Antiulcer Potential of Manuka Honey against Gastric Ulcer in Rats by Almasaudi SB1, El-Shitany NA2, Abbas AT3, Abdel-dayem UA4, Ali SS5, Al Jaouni SK6, Harakeh S. (PubMed)
(2) Manuka Honey Exerts Antioxidant and Anti-Inflammatory Activities That Promote Healing of Acetic Acid-Induced Gastric Ulcer in Rats by Almasaudi SB1, Abbas AT2, Al-Hindi RR1, El-Shitany NA3, Abdel-Dayem UA4, Ali SS5, Saleh RM6, Al Jaouni SK7, Kamal MA8, Harakeh SM. (PubMed)
(3) Protective effects of Manuka honey on LPS-treated RAW 264.7 macrophages. Part 2: Control of oxidative stress induced damage, increase of antioxidant enzyme activities and attenuation of inflammation by Gasparrini M1, Afrin S1, Forbes-Hernández TY1, Cianciosi D1, Reboredo-Rodriguez P2, Amici A1, Battino M1, Giampieri F3. (PubMed)
(4) The inflammation theory of diseas. The growing realization that chronic inflammation is crucial in many diseases opens new avenues for treatment by Philip Hunter. (PubMed)

Sunday, October 20, 2019

Herbal Turmeric Eradicate the progression of Prostate Cancer in Vitro and Vivo

Cancer is a class of medical conditions associated with cell growth irregularly due to the alternation of cell DNA with unknown causes.

Most cases of primary cancer start in the cell on the surface of the inner lining, before growing in size to invade other nearby healthy tissue and organ by spreading via lymph or blood.

The prostate formed part of the male reproductive organ, warped around the urethra, is a gland found in front of the rectum and just below the bladder that is responsible for making some of the semen to carry sperm.

Prostate cancer is a chronic condition caused by abnormal cell growth in the prostate tissue. Most prostate cancers are slow-growing and enlarged prostate and prostate cancer may be detected during the Physical (rectum) exams.

According to the statistics provided by the Cancer Net, prostate cancer is the most common cancer among men, besides skin cancer.

In 2019, approximately 174,650 men in the US will be diagnosed with prostate cancer with over 60% of cases in men over 65.

The average age of diagnosis is 66. The disease rarely occurs before age 40. The 5-year survival rate for most men with local or regional prostate cancer is nearly 100%.

Prostate cancer can be diagnosed by

*Digital Rectal Examination (DRE)

A digital rectal examination is included in a physical exam. In DRE, your doctor inserts a lubricated, gloved finger into the rectum to feel the surface of the prostate gland to check for any abnormality of the prostate.

* Transrectal Ultrasound (TRUS)
Ultrasound allows your doctor to visualize and assess the size of your prostate and check for any abnormality and surrounding area with an image taken from the test.

* Prostate-specific antigen (PSA) test
The test is to measure the levels of prostate-specific antigen (PSA), a protein produced by the prostate. The high levels of PSA may be an indication of higher risk of prostate cancer.

* Prostatic Acid Phosphatase (PAP) test
Prostatic acid phosphatase (PAP) is a test to measure the level of prostatic acid phosphatase, an enzyme produced by the prostate. The higher the levels of PAP is an indication of the disease progression.

* Prostate biopsy
In a prostate biopsy, samples of the prostate tissue are taken by a thin, tube-like instrument to examine under microscopy to review the stage of cancer.

Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

On finding a potential ingredient for the treatment of cancer, researchers examined the anticancer action of curcumin in hormone-independent prostate cancer cells (DU145, and PC-3).

Based on the tested differentiation, curcumin was more effective in the inhibition of PC-3 cells compared to that of DU145 cells.

In other words, curcumin induced cancer cells apoptosis, depending on the maspin expression associated with the inhibition of tumor progression.

More precisely, curcumin administration inhibited the maspin-knockdown cells involved in expression levels of pro-apoptotic proteins compared with control cells.

In other words, curcumin treatment promoted the expression of maspin that enhances the phytochemical sensitivity to prostate cancer cells.

Moreover, in a mouse prostate cancer xenograft model, curcumin treatment inhibited the growth of prostate cancer in vivo as well as promoting apoptosis of LNCaP cells in vitro.

The efficacy of curcumin on LNCaP cells.was attributed to the inhibition of the JNK pathway associated with cancer development and progression and regulation of gene (H3K4me3) expression.

Dr. Zhao W, the lead scientist wrote, "curcumin inhibits JNK pathway and plays a role in epigenetic regulation of prostate cancer cells by repressing H3K4me3".

Taken altogether, turmeric processed abundantly bioactive compound curcumin may be considered supplements for the prevention and treatment of prostate cancer, pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Curcumin suppressed the prostate cancer by inhibiting JNK pathways via epigenetic regulation by Zhao W1, Zhou X1, Qi G1, Guo Y2. (PubMed)
(2) Maspin Enhances the Anticancer Activity of Curcumin in Hormone-refractory Prostate Cancer Cells by Cheng WL1, Huang CY2,3, Tai CJ4,5, Chang YJ6,2,7,8, Hung CS. (PubMed)

Honey, the Natural Whole Food for Prevention and Treatment of Dandruff

Honey may have a potential effect in the prevention and treatment of dandruff, a common skin problem of many adults, some scientists suggested

Dandruff is a condition of the scalp most commonly caused by the dry skin resulting from dry air.

However, in many instances, the condition also is associated with seborrheic dermatitis. leading to rough, scaly skin on the scalp.

In other words, patients with oily skin accompanied by seborrheic dermatitis can lead to overexpression of yeast that causes the development of the large white flakes or yellow scales due to uneven shedding and clumping of dead skin cells.

Belief or not dandruff affects over 50% of the general population.

There are many causes of dandruff. Researchers suggested that dry skin, the use of wrong kinds of hair products and skin conditions such as seborrheic dermatitis or eczema are associated with the onset of dandruff.


In some people, an overgrowth of a yeast-like fungus can also cause dandruff.

The increase of age hormone imbalance and prolonged periods of stress are the most common prevalent risk factors associated with the condition.

Most cases of dandruff can be treated with daily shampoo to reduce the oil on the scalp. In severe cases, due to overexpression of fungi, pyrithione zinc shampoos may be recommended.

Honey is the miraculous product made by bees using nectar from flowers.

The rich golden liquid It is considered one of healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.

Dandruff, if left untreated can cause itchy and inflamed scalp that it lead to temporary hair loss.

On finding a natural ingredient for the prevention and treatment of dandruff with no side effects, researchers examine the anti-dandruff effects from honey, a bee-derived, supersaturated solution composed mainly of fructose and glucose, and contains proteins and amino acids, vitamins, enzymes, minerals, and other minor components.

The application of honey exerted a significant effect in reducing dandruff, through its moisturizing and antimicrobial property.

The effective doses range between 1 and 10%, but concentrations up to 70% can be reached by mixing with oils, gel, and emulsifiers, or polymer entrapment.

With an aim to reaffirming the honey anti-dandruff activity, a researcher at the Dubai Specialised Medical Centre and Medical Research Labs, investigated the potential use of topical application of crude honey in the management of seborrheic dermatitis and dandruff.

The study included 30 patients (20 patients were males and 10 were females, their ages ranged between 15 and 60 years) with chronic seborrheic dermatitis of scalp, face, and front of the chest.

Before applying honey to treat the condition, participants showed conditions of scaling, itching and hair loss. The lesions were scaling macules, papules and dry white plaques with crust and fissures.

All patients were asked to apply diluted crude honey (90% honey diluted in warm water) every other day on the lesions with gentle rubbing for 2-3 mins. And, honey was left for 3 hr before gentle rinsing with warm water.

After 4 weeks of treatment, honey showed a significant effect on prophylactic phase, which lasted for six months.

Furthermore, in half of the patients treated with the topical honey once weekly and the other half served as control.

The treatment group demonstrated a reduction of Itching and disappeared scaling within one week. Skin lesions were healed and disappeared completely within 2 weeks.

Moreover, honey administration also improved in hair loss.

None of the patients treated with the honey application once weekly experienced a relapse for six months

Dr. Al-Waili NS, after taking into account co and confounders, said, "crude honey could markedly improve seborrheic dermatitis and associated hair loss and prevent relapse when applied weekly".

The findings clearly suggested that honey may be considered a replacement of chemical ingredients for the prevention and treatment of dandruff associated with seborrheic dermatitis, with no side effects.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.

Sources
(1) Honey in dermatology and skin care: a review by Burlando B1, Cornara L.(PubMed)
(2) Therapeutic and prophylactic effects of crude honey on chronic seborrheic dermatitis and dandruff by Al-Waili NS1. (PubMed)

Saturday, October 19, 2019

Bioactive Compound Sulforaphane (SFN) Isolated from Collard Greens, Processes Anti-Neuropathic Pain in Vivo

Neurological disorders are a class of diseases of the nervous system characterized by the structural damage, biochemical or electrical abnormalities in the brain, spinal cord or nerves.

Neurodegenerative disease is a type of neurological disorder associated with the progressive loss of neurons in the brain caused by several mechanisms, including toxicity and oxygen deficiency.

Neuropathic pain is a type of pain that affects the somatosensory nervous system due to damage or disease. Abnormal sensations called dysesthesia or pain from normally non-painful stimuli (allodynia) are some of the most common forms of neuropathic pain found in patients.

There are no obvious causes of neuropathic pain. However, medical conditions such as alcoholism, amputation, diabetes, nerve problems, HIV infection or AIDS, multiple myeloma, multiple sclerosis and shingles, and chemotherapy are some prevalent factors of neuropathic pain.

According to the joint study conducted led by the Health Outcomes Practice, there are no published data on the broad prevalence of neuropathic pain (NeP) in the US. However, the 15,751 respondents reported pain (63.7%), of 2,548 data suggested that 10% of American may suffer from neuropathic pain (NeP). The rate of NeP in Blacks and Hispanics ethnicity was consistently higher compared to White

Most common treatments of NeP are the use of nonsteroidal anti-inflammatory drugs (44.2%), followed by weak opioids (31.7%), antiepileptics (10.9%), and strong opioids (10.9%).

Most common therapies used for neuropathic pain treatment are physical therapy, relaxation therapy, massage therapy, psychological therapy, and acupuncture accompanied by pain counseling.

Furthermore, in neuropathic pain caused by medical conditions such as diabetes, treatment may emphasize the management of the condition and improvement of quality of life by preventing further nerve damage.

In some cases, an invasive or implantable device may be used to manage the pain.


Collard Green is a species of Brassica Oleracea, belongings to the family Brassicaceae with unknown origin. Today, the plant is cultivated commercially for its thick, slightly bitter edible leaves.

With an aim to find a potential compound for the treatment of neuropathic pain, researchers investigated sulforaphane (SFN), a derivative of glucoraphanin present in cruciferous vegetables on inflammation-related diseases.

According to the tested analysis, SFN showed an anti-nociceptive effect in a neuropathic pain mouse model, sciatic nerve chronic constriction injury (CCI).

Furthermore, SFN injected intraperitoneally for 7 days inhibited the when pain behaviors, including mechanical allodynia and thermal hyperalgesia in CCI mice.

Moreover, SFN at a dose-dependently also attenuated CCI-induced pain behavioral hypersensitivity, by inhibiting the production of pro-inflammatory cytokines such as TNF-α, IL-1β, IL-6 that cause d neuropathic pain in mice and exhibiting the production of an anti-inflammatory cytokine such as IL-10 associated with pain relief.

More importantly, CCI enhancement of COX2 and iNOS in the induction of nerve injury were also counteracted by the administration of SFN.

Additionally, SFN treatment also increased the CCI-induced increase in µ-opioid receptors that are responsible for the analgesics, in injured sciatic nerves.

Based on the results, researchers said, "SFN has both anti-nociceptive and anti-inflammatory actions"

Taken altogether, collard green processed a high amount of SFN may be considered supplements for the prevention and treatment of neuropathic pain, pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Anti-nociceptive and anti-inflammatory actions of sulforaphane in chronic constriction injury-induced neuropathic pain mice by Wang C1, Wang C. (PubMed)
(2) The prevalence of probable neuropathic pain in the US: results from a multimodal general-population health survey by Marco D DiBonaventura,1 Alesia Sadosky,2 Kristen Concialdi,1 Markay Hopps,2 Ian Kudel,1Bruce Parsons,2 Joseph C Cappelleri,3 Patrick Hlavacek,2 Andrea H Alexander,2Brett R Stacey,4 John D Markman,5 and John T Farrar. (PMC)

Manuka Honey (MH) and Tualang Honey (TH), the Potential Natural Antibiotics Alternative with No Side Effects

Scientists may have found natural alternative antibiotics for the treatment of diseases caused by a bacterial infection, some studies found.

Infection is a medical condition caused by bacteria multiplication after entering the body.

Most bacteria were killed off by the white blood cells of the first line of defense of the immune system before they can enter the body.

In this stage, the immune system response stimulates the production of proteins associated with the production of coagulation to seal the wound and damage and pro-inflammatory cytokines to destroy the invaded bacteria, leading to symptoms of fever, skin redness in the infected area.

However, if they enter the body successfully, they can initiate infection through the stage of incubation where bacterial multiplying in the specific tissues and organs, leading to colonization and in facilitating disease development.

Patients with acute bacterial infection usually recover in a short period of time within 3 weeks.

Some bacterial pathogens can establish life-long chronic infections in the host by the persistent establishment after an acute infection period.


Dr. Young D, the lead scientist, at the Technology and Medicine, said," Bacteria have evolved specific pathogenic mechanisms and harbor sets of genes that contribute to the establishment of a persistent lifestyle that leads to chronic infection"

" Persistent bacterial infection may involve occupation of a particular tissue type or organ or modification of the intracellular environment within eukaryotic cells".

"Bacteria appear to adapt their immediate environment to favor survival and may hijack essential immunoregulatory mechanisms designed to minimize immune pathology or the inappropriate activation of immune effectors".


These results firmly suggested that if you have a weakened immune system you are at a higher risk to the onset of chronic bacterial infection.

Honey is the miraculous product made by bees using nectar from flowers.

The rich golden liquid It is considered one of healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.

On finding natural sources as a new antibiotic with no side effects, researchers examine the Manuka honey (MH) antibacterial effect in bioactive wound dressings.
Epidemiological studies suggested that MH provides unique antibacterial activity compared to conventional kinds of honey, due to its constituents, methylglyoxal (MGO).

In the evaluation of the antibacterial activity of both MH and MGO (at equivalent MGO concentrations) when applied as a physical coating to a nonwoven fabric wound dressing, researchers found that* Application of concentrations of 0.0054 mg cm-2 of MGO in the form of MH and MGO is sufficient to achieve a 100 colony-forming unit % bacteria reduction against gram-positive Staphylococcus aureus and gram-negative Klebsiella pneumonia.

* However, a 3- to 20-fold increase in MGO concentration (0.0170-0.1 mg cm-2) was required to facilitate a good antibacterial effect.

These results suggested that Manuka honey antibacterial activity processed a linearly and MGO concentration-dependent manner.

Dr. Bulman SEL, the lead scientist said, "The results presented in this study, therefore, demonstrate the relevance of an MGO-based coating as an environmentally friendly strategy for the design of functional dressings with antibiotic-free antimicrobial chemistries".

Additionally, in the investigation of the traditional use of Tualang honey (TH) for the treatment of bacterial infection against various microorganisms, including those from burn-related diagnoses, compared the anti antibacterial activity of Aquacel-Tualang honey, Aquacel-Manuka honey, Aquacel-Ag, and Aquacel- plain dressings against bacteria isolated from patients.
Four types of Gram-negative bacteria, namely Enterobacter cloacae, Klebsiella pneumoniae, Pseudomonas spp. and Acinetobacter spp., and three Gram-positive bacteria, namely Staphylococcus aureus, coagulase-negative Staphylococcus aureus (CONS) and Streptococcus spp. were included in the study.

All tested agents showed a significant effect inhibiting the total bacterial count on day 6 and onwards.

Aquacel-Ag and Aquacel-Manuka honey dressings gave a better zone of inhibition for Gram-positive bacteria compared to Aquacel-Tualang honey dressing.

The comparable results were also found in the Aquacel-Manuka honey and Aquacel-Tualang honey dressing against Gram-negative bacteria.

Researchers after taking into account co and confounders suggested that Tualang honey has a bactericidal as well as bacteriostatic effect and is easier to apply and less sticky compared to Manuka honey

Taken all together, there is no doubt that Manuka honey (MH) and Tualang honey (TH) may be considered a functional remedy for the prevention and treatment of bacterial infection. However, before they can be used as antibiotics similar to those of conventional medicine, a larger and multicenter human study is necessary to reconfirm the viability.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.

Sources
(1) Antibacterial Properties of Nonwoven Wound Dressings Coated with Manuka Honey or Methylglyoxal by Bulman SEL1, Tronci G2, Goswami P3, Carr C4, Russell SJ5.(PubMed)
(2) Antibacterial properties of tualang honey and its effect in burn wound management: a comparative study by Nasir NA1, Halim AS, Singh KK, Dorai AA, Haneef MN.(PubMed)
(3) The antibacterial properties of Malaysian tualang honey against wound and enteric microorganisms in comparison to manuka honey by Tan HT1, Rahman RA, Gan SH, Halim AS, Hassan SA, Sulaiman SA, Kirnpal-Kaur B.(PubMed)
(4) Chronic bacterial infections: living with unwanted guests by Young D1, Hussell T, Dougan G.(PubMed)

Friday, October 18, 2019

Bromelain Kills Breast Cancer Cells in Vitro

Breast cancer is a medical condition characterized by irregular cell growth in the breast tissue due to the alternation of DNA.

Most cases of breast cancer at the early stage start in the cells on the surface of the inner lining of either from the milk ducts (Ductal carcinoma) or the lobules (Lobular carcinoma) that supply the ducts with milk.

At this stage, the patient may first notice as a painless lump in the breast or armpit and most often discovered by herself or her partner.

However, some patients may also experience symptoms of nipple discharge (clear or bloody)
inverted or retracted nipple, scaly or pitted skin on nipple persistent tenderness of the breast and
unusual breast pain or discomfort.


At the advanced stage, besides experiencing symptoms shared commonly with other types of cancer, patients may also notice localized bleeding and severe pain due to the oversize that press on nearby blood vessels and nerves.

According to the U.S. Breast Cancer Statistics, approximately, 1 in 8 U.S. women or 12% will develop invasive breast cancer over the course of their lifetime.

In 2019, an estimated 268,600 new cases of invasive breast cancer are expected to be diagnosed in women in the U.S., along with 62,930 new cases of non-invasive (in situ) breast cancer.


The 5 years survival rate of breast cancer at the early stage is close to 100%.

The causes of breast cancer are not identified. Gender, aging, genetic preposition, family history, never pregnant women and smoking are some breast cancer prevalent risks.


Dr. Bhaskarapillai Binukuma, the lead scientist in the evaluation of the diet risk of breast cancer wrote, "Increased consumption of total fat and saturated fat were found to be positively associated with the development of breast cancer".


And, "A moderate inverse association between consumption of n-3 fatty acids and breast cancer risk and a moderate positive association between n-6 fatty acids and breast cancer risk were observed".


In other words, if you are a high-fat diet follower, your risk of breast cancer is increased substantially.

Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.

With an aim to find a natural ingredient for the treatment of breast cancer, researchers examined the bromelain-functionalized multiple-wall lipid-core nanocapsules (Bro-MLNC-Zn) on breast cancer cell line.

The complex used for the study was formed by a Zn-N chemical bond and a chelate with hydroxyl and carboxyl group.

In human breast cancer cells (MCF-7), the complex at the nanocapsule surface showed an antiproliferative effect by maintaining its proteolytic activity.

Interestingly, Bro-MLNC-Zn showed a reduced dose at 160-folds to exerted a similar effect compared to that of and bromelain solution.


Based on the results, researchers said, "The surface functionalization approach produced an innovative formulation having a much higher antiproliferative effect than the bromelain solution".


In order to reveal more information about bromelain anti-breast cancer activity, researchers investigated the possible synergistic cytotoxic effects of bromelain in combination with cisplatin on MDA-MB-231 human breast cancer cells.


Human MDA-MB-231 cells used in the study were treated with different concentrations (0.24-9.5 µM) of bromelain or cisplatin alone, as well as four different combinations.


According to the results of tested assays, single-agent treatment with cisplatin or bromelain decreases the viability of the MDA-MB-231 cells at 24 and 48 h in a dose- and time-dependent manner.


All combinations displayed synergistic effects against MDA-MB-231 cells at 48 h, particularly with combination 1 (bromelain 2 µM + cisplatin 1.5 µM).


Interestingly, combination 1 also was found to induce breast cancer cell death with a significant decrease in the levels of several apoptotic proteins but an increase of levels of the pro-apoptotic proteins compared with bromelain.


Taken altogether, bromelain used alone or combined with other herbal medicines may be considered supplements for the prevention and treatment of breast cancer, pending to the confirmation of the larger sample size and multicenter human study.


Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.



Sources
(1) Bromelain-Functionalized Multiple-Wall Lipid-Core Nanocapsules: Formulation, Chemical Structure and Antiproliferative Effect Against Human Breast CancerCells (MCF-7) by Oliveira CP1,2, Prado WA3, Lavayen V3, Büttenbender SL3, Beckenkamp A4, Martins BS3, Lüdtke DS3, Campo LF3, Rodembusch FS3, Buffon A4, Pessoa A Jr5, Guterres SS4, Pohlmann AR. (PubMed)
(2) Combination of cisplatin and bromelain exerts synergistic cytotoxic effects against breast cancer cell line MDA-MB-231 in vitro by Pauzi AZ1, Yeap SK2, Abu N1, Lim KL3, Omar AR2, Aziz SA4, Chow AL1, Subramani T1, Tan SG1, Alitheen NB. (PubMed)
(3) Dietary fat and risk of breast cancer by Bhaskarapillai Binukumar1 and Aleyamma Mathew. (PMC)

Manuka Honey, the Best for the Prevention and Treatment of Acute and Chronic Inflammatory Diseases

Honey may the next pharmaceutical target to identify the single ingredient medicine for the treatment of choric inflammatory disease, some scientists suggested.

Inflammation is a natural and systematic response of the immune system in the protection of the body against infection caused by the invasion of stimuli and pathogens.

After sensing the bodily injury or damage, the white blood cells of the immune first line of defense stimulates the production of a blood clot to seal the would quickly and proinflammatory cytokine to the site of infection with an aim to kill off all microorganisms which may cause harm to our body.

In this acute phase of the battle, most of the time is won by the immune system. However, overexpression of the pro-inflammatory cytokines can lead to the death of nearby healthy cells and improper skin healing with the formation of scars.

In some cases, certain proteins with duo anti and proinflammatory function also can switch to pro-inflammatory cytokines depending on the severity of the infection.

Chronic inflammation is a medical condition that lasts longer than 8 weeks, caused by the inability of the immune system to kill off all the microorganisms that have successfully entered the body during the acute phase of infection.

Some researchers suggested that the evolution of the immune system is to kill off the foreign micro invaders within the time frames of 8 weeks. If not, the immune system will adapt to the change, leading to chronic low-grade inflammation, a major cause of many chronic illnesses, including diabetes.

In some instances, chronic inflammation can also be caused by the immune system that mistakenly attacks the bodily tissue.

Dr. Philip Hunter in the study "The inflammation theory of disease" pinpointed the important cause of diseases associated with chronic inflammation, "Maria Abreu's research group at the University of Miami's Miller School of Medicine in the USA found that the incidence of colon cancer was linked directly to the expression of the Toll-like receptor 4 (TLR4) gene".
"TLRs are crucial in alerting the immune system to microbial infection, triggering acute inflammatory responses that clear invading pathogens. However, TLR4 can also maintain chronic inflammation, for example by responding to commensal bacteria in the gut. As such bacteria are constantly replenished through food intake, and therefore cannot be permanently cleared by the immune system, this can lead to persistent chronic infection maintained by TLRs. "

Honey is the miraculous product made by bees using nectar from flowers.

The rich golden liquid is considered one of healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.

On finding an ingredient or whole food for the prevention and treatment of acute and chronic inflammatory diseases, scientists at the Menoufia University examine the honey effects in a rat model of colitis induced by the injection of dextran sodium sulfate (DSS).

Application of natural honey showed a strong effect on the prevention of tissue injury and inflammatory infiltration by inhibited by proteins associated with the production of proinflammatory cytokine and overexpression of reactive oxygen species.


Further examination of the honey effect, researchers indicated that the honey-treated group had significantly improved macroscopic and microscopic scores and inhibited the apoptotic markers.


At the end of the experiment, researchers said, "the beneficial role of natural honey in the treatment of DSS-induced colitis via the inhibition of colonic motor dysfunction and the inflammatory-oxidative-apoptotic cascade" and "the role of honey in epithelial regeneration was clarified", after taking into account co and confounders.


Moreover, in order to understand the gastroprotective effects of manuka honey against ethanol-induced gastric ulcers in rats, researchers examined the joint studies led by King Abdulaziz University, including 4 of our groups of rats randomly assigned to control, ethanol (ulcer), omeprazole, and manuka honey.

During the stud, the Manuka honey treated group displayed a significantly decreased ulcer index, completely protected the mucosa from lesions, and preserved gastric mucosal glycoprotein.

Manuka honey treated group also showed increased levels of antioxidants enzymes which were suppressed by the injection of ethanol to an induced ulcer.

Manuka honey also decreased gastric mucosal MDA, the oxidative stress marker and plasma of proinflammatory cytokines.

Dr. Almasaudi SB, the lead scientist wrote in the final report, "manuka honey likely exerted its antiulcer, effect by keeping enzymatic (GPx and SOD) and nonenzymatic (GSH and NO) antioxidants as well as inflammatory cytokines (TNF-α, IL-1β, and IL-6) in a reduced form, inhibited lipid peroxidation (MDA), and preserved mucous glycoproteins levels".


Taken altogether, Manuka honey may be considered a functional food for the prevention of inflammation and combined with the primary medicine for the treatment of chronic inflammatory diseases with no side effects.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.

Sources
(1) The dual anti-inflammatory and antioxidant activities of natural honey promote cell proliferation and neural regeneration in a rat model of colitis by Nooh HZ1, Nour-Eldien NM2.(PubMed)
(2) Antioxidant, Anti-inflammatory, and Antiulcer Potential of Manuka Honey against Gastric Ulcer in Rats by Almasaudi SB1, El-Shitany NA2, Abbas AT3, Abdel-dayem UA4, Ali SS5, Al Jaouni SK6, Harakeh S. (PubMed)
(3) Manuka Honey Exerts Antioxidant and Anti-Inflammatory Activities That Promote Healing of Acetic Acid-Induced Gastric Ulcer in Rats by Almasaudi SB1, Abbas AT2, Al-Hindi RR1, El-Shitany NA3, Abdel-Dayem UA4, Ali SS5, Saleh RM6, Al Jaouni SK7, Kamal MA8, Harakeh SM. (PubMed)

Thursday, October 17, 2019

Healthy Legume Navy Bean Prevents the Onset OF Oxidative Stress Naturally

Oxidative stress is a condition associated with overexpression of free radicals as a result of a chain reaction that can not be stopped.

More precisely, oxidative stress is caused by the imbalance of the ratio of free radicals and antioxidants produced by the host.

Antioxidants are stable atoms that inhibit oxidation.

Over time, oxidative stress induces damage of protein, lipid, and cell DNA can lead to the incidences of chronic disease, including heart disease, diabetes, and cancers.

Free radicals are unstable atoms with an unpaired electron in the outer ring. Therefore, in order for them to become stable, free radicals are ready to steal or donate an electron from or to other atoms.

Oxidative stress can be preventable if antioxidants in the body can pair all electrons in the outer ring.

The overexpression of free radicals is bad. However, free radicals generated from cell metabolism may play a critical role in the synthesis of energy and essential molecules and boosting the immune system.

Believed it or not, skin aging is a result of the accumulation of damage inflicted by reactive oxygen species (ROS), according to the free radical theory.

In a healthy individual, antioxidant enzymes produced by the body are more than enough to accounter the expression of free radicals occurred in our body every day.

However, in people with a weakened immune system such as the elderly, the intake of dietary antioxidants such as supplements or fruits rich with antioxidants may be the only option to improve levels of antioxidants in the body.

Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.

The herbal plant has been used in traditional medicine as liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.


The small, white navy bean, also called pea bean or haricot, popular in both dry and green forms, is very popular in Britain and the US, native to Peru. It is now grown and consumed across the world, due to its numerous health benefits.

With an aim to find a potential compound for the prevention and treatment of diseases associated with oxidative stress, researchers examined the effects of black and navy beans containing non-digestible fermentable components (SCFA precursors) and phenolic compounds (phenolic acids, flavonoids, and anthocyanins) antioxidant and anti-inflammatory activity.

In an animal model, C57BL/6 mice were fed a 20 % navy bean or black bean flour-containing diet or an isoenergetic basal diet (BD) for 2 weeks before the induction of experimental colitis via 7 d dextran sodium sulfate (DSS, 2 % (w/v) in the drinking water) exposure, researchers showed that
* Cooked black and navy bean diet increased caecal SCFA and fecal phenolic compound concentrations (P< 0·05) inhibit the colonic and systemic inflammation.

* Both beans diet reduced mRNA expression of colonic inflammatory cytokines such as IL-6, IL-9, IFN-γ, and IL-17A) and increased anti-inflammatory cytokines such as IL-10.

* Furthermore, systemic inflammatory circulating cytokines (IL-1β, TNFα, IFNγ, and IL-17A, P< 0·05) in the acute and chronic inflammation and biomarkers associated with oxidative stress caused by the injection of dextran sodium sulfate (DSS) are also inhibited by the cooked black and navy beans.

* Unfortunately, both bean diets also are found to enhanc3 DSS-induced colonic damage, according to the increased histological injury score and apoptosis

Based on the findings, researchers suggested that bean-containing diets exerted both beneficial and adverse effects during experimental colitis by reducing inflammatory biomarkers both locally and systemically while aggravating colonic mucosal damage.

In other words, black and navy bean diet inhibit parameters involved in inflammation and oxidative stress and have a negative impact on colitis severity.

Taken altogether, navy beans may be considered a remedy for the prevention and treatment of diseases associated with oxidative stress, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Cooked navy and black bean diets improve biomarkers of colon health and reduce inflammation during colitis by Zhang C1, Monk JM1, Lu JT1, Zarepoor L1, Wu W1, Liu R1, Pauls KP2, Wood GA3, Robinson L4, Tsao R1, Power KA. (PubMed)

Honey, Better Than Over the Counter Medicine for Treatment of Acute Cough in Children

Scientists may have found a natural whole food that processes a significant activity in reducing the risk and treatment of acute coughing in children with no side effects, some studies suggested.

Coughing can be a natural and reflex reaction to expel phlegm from the airway or a result of viral and bacterial infection of the upper airway.

A cough that lasts less than three weeks is considered an acute cough.


A chronic cough is a medical condition that lasts more than 3 weeks. In children, the condition can be caused by allergies and sinusitis, asthma, whooping cough, cystic fibrosis, aspiration, acid reflux and a blockage in the airway.


Most common causes of acute cough are cold and flu. However, the chronic condition in adults can be the result of smoking, sinus infection, allergic rhinitis, and diseases associated with upper airway dysfunction, including asthma, chronic bronchitis and long-term use of angiotensin-converting enzyme (ACE) inhibitors for the treatment of high blood pressure.


Most common symptoms of coughing in children are accompanied by the itchy throat, runny nose, watery eyes, sore throat, or rash.

Most parents use over the counter medicine for the treatment of acute coughing in children such as antitussives and expectorants

However, according to the warning from the FDA, warns that children younger than 12 shouldn’t take codeine products to treat pain or cough because of the risk of developing potentially life-threatening breathing problems.

"The FDA recommends against the use of codeine in youths ages 12 through 18 who are obese or have conditions such as obstructive sleep apnea (blocked airflow during sleep) or severe lung disease. These risk factors can increase their chances of developing serious breathing problems when taking these medications".

Therefore, if your child experiences severe coughing, you may want to check your doctor before applying any over the counter medicine. Most cases of acute coughing in children are recovered within a few days.

Please noted that there’s no cure for the common cold caused by a viral infection. You will get better on your own in a week or two without needing medications and your child will get better on their own in a week or two without the need for medications.

Honey is the miraculous product made by bees using nectar from flowers.

The rich golden liquid is considered one of healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.

On finding a natural ingredient or whole food for the treatment of acute coughing accepted by children without inducing any side effects, researchers examined the effectiveness of honey for an acute cough in children in ambulatory settings.

The study includes the searching of available randomized controlled trials (RCTs) comparing honey, given alone, or in combination with antibiotics, versus nothing, placebo or other over-the-counter (OTC) cough medications to participants aged from two to 18 years for an acute cough in ambulatory settings.

Out of hundreds of studies reviewed by the researchers, only 2 studies were selected for the review.

Compared to dextromethorphan, diphenhydramine and 'no treatment' on symptomatic relief of a cough using the 7-point Likert scale. honey was much better medicine than no treatment in reducing the frequency of cough and exerted similar or better effects to those of over counter medicine.

However, mild adverse events were found in seven children (9.3%) from the honey group and two (2.7%) from the dextromethorphan group.

After taking into account co and confounders, Dr. Oduwole O. the lead scientist said, "There was no significant difference between honey versus dextromethorphan or honey versus diphenhydramine".

Futhermore, in the concerns of the side effects of honey and over the counter medicine, researchers examine the effects of two kinds of Iranian honey with diphenhydramine (DPH) on nocturnal pediatric coughs and the sleep quality of children and their parents.

A total of 87 patients included in the study were randomly assigned to one of three treatment groups: Group 1, Honey type 1 (Kimia Company, Iran) (n = 42), Group 2, Honey type 2 (Shahde-Golha, Iran) (n = 25), and Group 3, DPH (n = 20).


Each group received double doses of the respective treatments on two successive nights, researchers indicated that
* Honey type 1 was superior to DPH in improving all aspects of coughs, except the frequency,

* Honey type 2 was more effective than DPH in improving all aspects of coughs, except the sleep quality of the child.

* There was no significant difference between Honey type 1 and 2 in any aspects of cough relief.

After examing the standard validated questionnaire completed by the parents before and after treatment.

Dr. Ayazi P, the lead author wrote in the final report, " honey may provide better cough relief than DPH in children and improve the sleep quality of children and their parents".

By comparing the above studies, there is no doubt that honey may be used for the treatment of acute cough in children.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.

Sources
(1) Honey for an acute cough in children by Oduwole O1, Meremikwu MM, Oyo-Ita A, Udoh EE. (PubMed)
(2) Comparison of the Effect of Two Kinds of Iranian Honey and Diphenhydramine on Nocturnal Cough and the Sleep Quality in Coughing Children and Their Parents by Ayazi P1, Mahyar A2, Yousef-Zanjani M1, Allami A3, Esmailzadehha N4, Beyhaghi T. (PubMed)

Wednesday, October 16, 2019

Turmeric Protects the Liver Against the Risk of Hepatic Steatosis in Obese

The liver is the largest internal organ that not only plays an essential role in cleansing the blood coming from the digestive system before passing them to other parts of the body but secrets cholesterol to aid digestive function, produce steroid hormones and vitamin D and build strong cell walls.

Steatosis is a condition caused by abnormal retention of lipids within a cell or organ. Hepatic steatosis is a medical condition caused by the accumulation of fat in the liver.

In other words, if the fat of your liver is more than 5% of liver weight, you are considered to have hepatic steatosis. Over time, untreated hepatic steatosis can lead to advanced forms of nonalcoholic fatty liver disease which have been found to induce negatively the function of the liver, particularly. in patients with obesity-associated with alcohol intoxication and/or hepatic disorders.

There are several mechanisms involved in the accumulation of intrahepatic fat, including increased flux of fatty acids to the liver, increased de novo lipogenesis, and/or reduced clearance through β-oxidation or very-low-density lipoprotein secretion.

People who are obese, having the condition of insulin resistance or diabetes, dyslipidemia, hypertension, metabolic syndrome, rapid weight loss, using hepatotoxic medications total parenteral nutrition (TPN) are at the increased risk of hepatic steatosis.

Conventionally, there is no effective treatment of liver steatosis. However, treatment of liver steatosis in obese patients is focusing to reduce weight and symptoms and improve quality of life, totally depending on the severity of the disease.

Usually, weight loss through a combination of a healthy diet and exercise is also the first line of treatment. in patients with an advanced stage of liver fibrosis, (cirrhosis) liver transplantation may be an option.


Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as an anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

On finding a natural compound for the prevention of liver steatosis, researchers examined the alleviation effect of KBH-1, an herbal mixture of Saururus chinensis, Curcuma longa and Polygala tenuifolia in obesity-induced hepatic steatosis.

The experiment included HepG2 cells, primary neuronal cells and a high-fat diet (HFD)-induced obesity rat model in vitro and in vivo.


According to the tested assays, KBH-1 not only suppressed the lipid deposition in HepG2 cells exposed to free fatty acids (FFA) but also significantly inhibited major factors in lipogenesis associated with the formation of fat and promoted major factors in lipolysis involved in breaking down of fats.

In the high fat-induced obesity model, KBH-1 improved hepatic steatosis by alleviating the effects on lipogenic genes and kinases similarly to those in vitro.

Furthermore, KBH-1 significantly improved the leptin-mediated signals that regulate food intake, energy expenditure, metabolism,.. impaired by obesity or FFA in the obesity model.


Moreover, according to the HPLC analysis, onji-saponin B and curcumin found in the formula has also potently suppressed the level of triglycerides.

In other words, KBH-1 activated the expression of AMP-activated protein kinase (AMPK) associated with the regulation of energy metabolism that stimulates glucose uptake and lipid oxidation to produce energy and suppressed the expression of PPARγ involved in hepatic steatosis... in obesity.


Based on the findings, researchers wrote, "These findings show the potential of KBH-1 as a functional food supplement or preventive agent in the treatment of obesity (.associated with hepatic steatosis)".

Taken altogether, turmeric processed abundantly bioactive compound curcumin may be considered supplements for the prevention and treatment of hepatic steatosis in obese, pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) KBH-1, an herbal composition, improves hepatic steatosis and leptin resistance in high-fat diet-induced obese rats by Lee JH1, Lee JJ1, Cho WK1, Yim NH1, Kim HK2, Yun B2, Ma JY. (PubMed)
(2) The effects of herbal composition Gambigyeongsinhwan (4) on hepatic steatosisand inflammation in Otsuka Long-Evans Tokushima fatty rats and HepG2 cells by Yoon S1, Kim J1, Lee H1, Lee H1, Lim J1, Yang H2, Shin SS3, Yoon M. (PubMed)

Honey, The Best to Inhibits Chemo-toxicity and Improves Chemotherapy For Treatment of Cancers

Honey may be considered an adjunct therapy combined with the chemo drug in the improvement of the drug efficacy and reduction of chemo toxicity for the treatment of cancers, some scientists found.

Cancer is a class of chronic diseases characterized by cell growth irregularly and disorderly in the tissue of specific organs, depending on the type of cancer.

Most cases of cancer are the result of the alternation of DNA in the cell located on the surface of the inner lining of an organ. Most patients may not experience any symptoms at the early stage.

However, as cancer progresses, the continued growth tumor may cause pressure on the nearby healthy organs and nerve cells, leading to localized symptoms and severe pain.

At the 4th stage of cancer, malignant cells may metastasize to other organs a distance away from the original site.

According to the statistic from the National Cancer Institute, approximately, 38.4% of men and women will be diagnosed with cancer at some point during their lifetimes.

In 2017, over 15,000 children and adolescents ages 0 to 19 were diagnosed with cancer and 1,790 died of the disease.
Chemo drugs are medicine used for the treatment of cancer by killing cancer cells that have been spread to other tissue or organ.

Chemotoxicity is the side effects of chemo drugs.

Most common symptoms of chemo drugs include the effect of blood-forming cells in the bone marrow, on hair follicles and cells in the mouth, digestive tract, and reproductive system, probably due to the medicine designed to kill cells indiscriminately.

According to the information of the pharmaceutical company, doxorubicin (Adriamycin) is one of the most powerful chemotherapy drugs ever invented by mankind.

The chemo drug used to treat a wide variety of cancers can kill cancer at every point in their life cycle.
Unfortunately, the drug can also damage heart cells and cause serious side effects, such as hair loss, breathlessness, feeling sick and easily infected.
Honey is the miraculous product made by bees using nectar from flowers.

The rich golden liquid It is considered one of healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.

On finding a natural ingredient or whole food which processes chemopreventive properties and anti chemo toxicity during cancer treatment, researchers evaluate the effect of Kelulut honey (KH), produced by the stingless bees from Trigona species against colon cancer induced in the animal model.

A total of 24 male Sprague Dawley rats aged 5 weeks are included in the study.
Rats were divided into 4 groups: (G1) untreated group not induced with AOM, (G2) untreated group induced with AOM, (G3) treated group induced with AOM, and (G4) treated group not induced with AOM.
Injection of AOM (15 mg/kg) was via intraperitoneal route once a week for two subsequent weeks to induce colorectal cancer.
The treatment groups were given oral administration of KH (1183 mg/kg body weight) twice daily for 8 weeks.

AOM injected group showed a significant increase in the total number of aberrant crypt foci (ACF) and aberrant crypts (AC) and crypt multiplicity and damage of liver and kidney

After treatment of KH, AOM group displayed a reduction of crypts and chemotoxicity by restoring the liver and kidney function observed by blood profile.

Furthermore, KH was not toxically identified by the KH treated group not induced with AOM.

These results suggested that KH may have a potential effect on inhibiting the toxicity caused by chemotherapy and improving the chemo drugs activity without inducing any side effects.


Moreover, on finding a natural whole food to overcome 5-fluorouracil (5-FU) therapeutic resistance and adverse toxicity in colorectal cancer, researchers looked into Manuka honey (MH), a rich source of bioactive compounds to examine its anticancer effects on human colon cancer HCT-116 and LoVo cells.

Compared to 5-FU alone, MH synergistically enhanced the chemotherapeutic effects of 5-FU, by reducing cell proliferation through the suppression of enzymes and proteins associated with the function in stimulating cancer cell multicity and activation of pathways associated to cell death programming.

Combined with chemo drug 5-FU, MH promoted the expression of antibody production and production of ROS in the induction of cytotoxicity activity against cancer cells without causing to harm to the nearby cells and tissue.

This result was observed by the reducing antioxidants produced by the cancer cells and increasing oxidative stress in the tumor.

Additionally, MH also induced cancer cell apoptosis through cell cycle arrest.

The findings clearly indicated MH could be a useful preventive or adjuvant agent in the treatment of colorectal cancer with 5-FU by inhibiting the toxicity and cancer cell resistance.

Taken altogether, KH and MH can be considered functional foods for the prevention and an adjunct therapy combined with the primary medicine for the treatment of cancer without inducing chemotoxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.

Sources
(1) Chemopreventive Properties and Toxicity of Kelulut Honey in Sprague Dawley Rats Induced with Azoxymethane by Saiful Yazan L1, Muhamad Zali MF2, Mohd Ali R3, Zainal NA2, Esa N4, Sapuan S4, Ong YS4, Tor YS4, Gopalsamy B2, Voon FL2, Syed Alwi SS. (PubMed)
(2) Manuka honey synergistically enhances the chemopreventive effect of 5-fluorouracil on human colon cancer cells by inducing oxidative stress and apoptosis, altering metabolic phenotypes and suppressing metastasis ability by Afrin S1, Giampieri F1, Forbes-Hernández TY1, Gasparrini M1, Amici A1, Cianciosi D1, Quiles JL2, Battino M. (PubMed)

Tuesday, October 15, 2019

Herbal Bilberry Protects the Kidney Against Damage

Kidneys are one of the main detoxed organs which filter the blood before passing the clear blood back to the circulatory system, located on either side of the spine.

In other words, kidneys remove wastes and extra water from the blood to form urine.

Most wastes in the blood are the results of from normal breakdown of active muscle and the foods you eat.

Believe it or not,1 in 3 adults in the United States are at risk of getting kidney disease. According to the statistics provided by the CDC, approximately, 30 million people or 15% of US adults have chronic kidney disease (CKD), including 48% of those with severely reduced kidney function but not on dialysis are not aware of having CKD.

Nephrotoxicity caused by overdose or longterm used medication and exposed to toxins is one of the most common kidney problems, leading to acute and chronic kidney damage.

Other risk factors associated with kidney damage include diabetes, high blood pressure, and cardiovascular disease.


Some researchers suggested the rise of kidney disease in the US adults may be influenced by the increase of obesity, the condition of excess fat accumulation, particularly on the waist.


Dr. Csaba P. Kovesdy, the lead scientist wrote, "Obesity has become a worldwide epidemic, and its prevalence has been projected to grow by 40% in the next decade".


And "In individuals affected by obesity, a compensatory hyperfiltration occurs to meet the heightened metabolic demands of the increased body weight. The increase in intraglomerular pressure can damage the kidneys and raise the risk of developing CKD in the long term. The incidence of obesity-related glomerulopathy has increased 10-fold in recent years. Obesity has also been shown to be a risk factor for nephrolithiasis, and for a number of malignancies including kidney cancer".

Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.

The plant berry has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.

With an aim to find a potent compound that protects the kidney against damage, researchers examined the anti nephrotoxic activity of bilberry ( Vaccinium myrtillus L.).

In an experimental model, induced serious kidney damage by a single intraperitoneal administration of 200 mg/kg KBrO3 induction of the increase in serum blood urea nitrogen (BUN) and creatinine levels, researchers compared the effects of five-day oral administration of bilberry ( Vaccinium myrtillus L.) extract at 50, 100, and 200 mg/kg.

All doses normalized the levels of creatinine and reversed serum BUN.

In other words, bilberry extracts protect the kidney by inhibiting the toxicity caused by the injection of 200 mg/kg KBrO3.


The efficacy of bilberry extracts was attributed also to decreased kidney stress marker malondialdehyde (MDA), expression of free radicals associated with nitric oxide (NO), and xanthine oxidase (XOD) levels.

Futhermore, bilberry extract improved oxygen radical absorbance capacity (ORAC) levels in kidney tissue against the overexpression of ROS and NOS.

The results strongly suggested that bilberry protects the kidney by reducing the degree of oxidative stress and kidney damage induced by KBrO3.

Dr. Bao L, the lead scientist wrote in the final report, "These findings demonstrate that the protective effect of bilberry extract is attributed to its free radical scavenging activity and lipid peroxidation inhibitory effect".

Taken altogether, bilberry may be considered a functional remedy for the prevention and treatment of diseases involved in kidney damage, pending to the validation of larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Protective effects of bilberry (Vaccinium myrtillus L.) extract on KBrO3-induced kidney damage in mice by Bao L1, Yao XS, Tsi D, Yau CC, Chia CS, Nagai H, Kurihara H. (PubMed)
(2) Obesity and Kidney Disease. Hidden Consequences of the Epidemic by Csaba P. Kovesdy,1,2 Susan L. Furth,3 Carmine Zoccali,4 and on behalf of the World Kidney Day Steering Committee. (PMC)

Honey, The Functional Food Which Kills Bladder Cancer Cells in Vivo and Vitro, Scientists Find

Scientists may have found a natural food source that processes the potential for the treatment of bladder cancer with no side effects, some studies suggested.

Bladder cancer is a medical condition characterized by irregular cell growth in the bladder.

Most cases of the primary bladder cancer start in the cell on the surface of the inner lining of the bladder tissue.

At the early stage, most bladder cancers do not cause any symptoms. However, at the advanced stage, the prostate can cause a distance metastasis to infect other healthy tissue and organ through the circulation of blood and fluids.

At this advanced stage, patients may experience symptoms of pain and blood in the urine caused by the proliferative tumor-suppressing the nerve cells and breaking the blood vessels in the bladder.

Researchers do not the exact causes of bladder cancer. But certain risk factors such as tobacco use, aging, gender, ethnicity, long-term bladder condition and exposure to chemicals are at a higher risk of the onset of the disease.

The warning from the FDA also suggested the diabetes drug pioglitazone for more than 1 year may have a higher risk of developing bladder cancer.

In fact, most people with some of the above risk factors have never developed bladder cancer even they are associated with the increased risk all their life.


Although most scientists agree that tobacco use is the major cause of bladder cancer, genetic preposition, according to the epidemiological studies is also the substantial risk of bladder cancer, such as the genetic mutations in some chromosomal genes, such as FGFR3, RB1, HRAS, TP53, TSC1, and others, occur which form tumors in the urinary bladder.


Sadly, People with gene mutation are at the 70 % higher risk of bladder cancer compared to those do not.

Dr. Zhang X, the lead author in the study "Bladder Cancer and Genetic Mutations" specified, "The changes in the genes of human chromosome 9 are usually responsible for tumor in bladder cancer, but the genetic mutation of chromosome 22 can also result in bladder cancer". and "The 18 different bladder tumors were evaluated, and 11 (61 %) had genetic mutations of p53 gene".

And, "The 18 different bladder tumors were evaluated, and 11 (61 %) had genetic mutations of p53 gene".

Honey, is the miraculous product made by bees using nectar from flowers.

The rich golden liquid is considered one of healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.

With an aim to find a natural ingredient for the prevention and treatment of bladder cancer without inducing any side effects, researchers at the University of Tsukuba conducted an experiment to examine the antitumor effect of bee honey against bladder cancer in vitro and in vivo.


The study included three human bladder cancer cell lines (T24, 253J, and RT4) and one murine bladder cancer cell line (MBT-2).

In vitro studies application of honey significantly inhibited the proliferation of T24 and MBT-2 cell lines by 1-25% honey and of RT4 and 253J cell lines by 6-25% observed by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay.


Broodeoxyuridine (BrdU) labeling index, an indicator of early tumor response to the injection of honey was lower in vitro.

FCM showed lower S-phase fraction, as well as the absence of aneuploidy compared with control cells.

Flow cytometry (FCM). in the measurement of can cancer cells physical and chemical characteristics showed lower S-phase fraction and the absence of aneuploidy compared with control cells, an indication of inhibitory cancer cells by the application of honey.

Furthermore, In the in vivo, intralesional injection of 6 and 12% honey, as well as oral ingestion of honey, significantly inhibited tumor growth.
These results suggested that bee honey processes a significant activity for inhibiting the growth of T24, RT4, 253J, and MBT-2 bladder cancer cell lines in vitro.

And, honey is also effective when administered intralesionally or orally in the MBT-2 bladder cancer implantation models.

Dr, Swellam T, the lead author after taking into account co and confounders wrote, " Our results are promising,,,,,, the mechanisms of the antitumor activity of honey".

Taken altogether, honey may be considered a functional food for the prevention and an adjunct therapy combined with the primary medicine for the treatment of bladder cancer.


However, further data collection large example size and multi-centers studies performed with human consumption of the whole food or its bioactive compounds during the course of the disease will be necessary to complete the picture of honey anti-bladder cancer possibilities.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Antineoplastic activity of honey in an experimental bladder cancer implantation model: in vivo and in vitro studies by Swellam T1, Miyanaga N, Onozawa M, Hattori K, Kawai K, Shimazui T, Akaza H. (PubMed)
(2) Bladder Cancer and Genetic Mutations by Zhang X1, Zhang Y. (PubMed)