Black Bean in Attenuated Risk and Treatment of Prostate Cancer

Intake of black bean regular may associate with ameliorated risk and treatment of prostate cancer, an Asian study reported. Particularly, people who follow the Southern pattern of diet showed a reduction in the risk of prostate cancer with approached statistical significance.


Black bean, a small roughly ovoid legume with glossy black shells, genus Phaseolus, belongings to the family Fabaceae can be bought in most grocery stores all around the year in dried and canned forms. It is believed that black bean was first domesticated growth in South America.

According to the National Taiwan University, fermentation products BN999, included black bean processed an anti-prostate cancer effect through the expression of prostate adenocarcinoma PC-3 cell line.



BN999, the product mixture induced cancer cell death by activating the protein gene involved pro-cancer cell apoptosis via cell mediatory activities, including a network of membranous anatomical structure and double membrane-bound organelle.in energy conversion.



Most importantly, BN999 targets the prostate and another cancer cell without affecting the normal human cells and inducing obvious side effects.

Furthermore, water-soluble black bean condensed tannins isolated from black beans showed significant activity in induced cancer cell death by apoptosis without affecting the growth of normal cells, in a dose-dependent manner.

Additionally, the study also addressed that the efficacy of water-soluble in induced prostate cancer cell death may be attributed to a direct effect in decrease cancer cell energy molecule and formation of cell structure.



Dr. Bawadi HA, the lead author indicated, after 24 h of injection, water-soluble black bean condensed tannins showed strongly reduced coagulation of blood in stimulated cancer cell migration and regulated mechanisms involved growth of prostate cancer in the formation of new blood vessels.

The findings suggested that black bean with plenty of phytochemicals may be considered as functional food used alone or combination with other superfoods for attenuated risk and treatment of prostate cancer.


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Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Soureces
(1) Fermentation product of soybean, black bean, and green bean mixture induces apoptosis in a wide variety of cancer cells by Chia JS1, Du JL, Wu MS, Hsu WB, Chiang CP, Sun A, Lu JJ, Wang WB.(PubMed)
(2) Dietary patterns and prostate cancer risk in the National Health and Nutrition Examination Survey Epidemiological Follow-up Study cohort by Tseng M1, Breslow RA, DeVellis RF, Ziegler RG.(PubMed)