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Saturday, July 23, 2022

Honey, the Best Natural Remedy for Chronic Otitis Externa With No Side Effects

In seeking natural therapy with no side effects, scientists may have found a herbal medicine for the prevention and treatment of acute otitis externa, according to studies.

Acute otitis externa is a condition characterized by the inflammation of the ear canal. Most cases of acute cute otitis externa are associated with the infection by Pseudomonas aeruginosa and Staphylococcus aureus due to improper cleaning.

However, people with seborrhoeic dermatitis caused by inflammation of greasy areas of the skin can also lead to infection of the ears.

The most common symptoms of acute otitis include itching, canal edema, canal erythema, and otorrhea.



Most cases of acute otitis externa are healed within days with proper ear drops. However, there is a rare case where the disease may take weeks or months to recover.


Chronic otitis externa shares the common symptoms of the acute form, accompanied by water retention and severe ear pain, and temporary loss of hearing, due to building up thick and dry skin that can build up inside the ear canal, leading to narrowing of the ear canal.

Untreated chronic otitis externa can cause deafness.

Besides sharing the risk factors with the acute form, otitis externa can also be caused by infection due to the long-term use of hearing aids and earplugs.


Unlike the acute form, most cases of otitis externa are treated with steroid drops in addition to antibiotics accompanied by oral intake of pain medications such as ibuprofen.


Generally, oral antibiotics are not recommended, however, if the infection has spread beyond the ear canal, oral antibiotics may be applied.


According to the statistics, otitis externa affects 1–3% of people in America a year and 95% of people's complaints of the condition are acute.


Honey, the rich golden liquid is a miraculous product made by bees using nectar from flowers.

The liquid is considered one of the healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.

The finding of a natural ingredient for the treatment of eczematous external otitis, scientists investigated the antibacterial potential of medical honey eardrops as a treatment of eczematous external otitis.


15 patients diagnosed with recurrent eczematous external otitis were selected and treated with medical honey eardrops for 2 weeks.

Honey treatment resulted in less discomfort and itching and decreased signs of eczema with no side effects, according to assays.


Although honey eardrops showed a strong in vitro inhibitory activity against all tested strains, it did not eradicate Staphylococcus aureus infection.

Honey eardrops also reduced the visual analog scale of ear complaints, and a score of eczema, and increased the eradication of bacterial infection. Most patients in the study, are satisfied with the use of honey eardrops for the treatment of their eczematous external otitis.


Dr. Henatsch D, the lead scientist, after taking into account co and confounders said, "The results of this preliminary study indicate a possible role of honey eardrops in eczematous ear disease".

Taken altogether, honey may be considered a functional remedy for the treatment of eczematous external otitis, pending the confirmation of a larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Ovarian Cysts And PCOS Elimination
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Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca



Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Treatment of Recurrent Eczematous External Otitis with Honey Eardrops: A Proof-of-Concept Study by Henatsch D1, Nabuurs CH1, van de Goor RM1, Wolffs PF2, Stokroos RJ. (PubMed)
(2) Alternative Treatments for Atopic Dermatitis: An Update by Shi K1, Lio PA. (PubMed)
(2) Acute Otitis Externa: An Update by PAUL SCHAEFER, MD, PhD, and REGINALD F. BAUGH, MD. (AAFP)

Saturday, July 9, 2022

Honey, the Best Natural Treatment For High Blood Pressure with No Side Effects, Scientists Say

In seeking natural therapy with no side effects, scientists may have a herbal remedy for normalizing blood pressure, according to studies.

Hypertension is a chronic condition caused by abnormally high blood pressure.

High blood pressure is a condition of a cluster of metabolic syndrome associated with the increased risk of heart disease and stroke.

Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood.

In high blood pressure individuals, due to the elevated blood pressure in your arteries, the heart has to work harder than normal to pump blood through the blood vessels.

In low blood pressure individuals, the reduced blood pressure in the arteries drops can cause the heart to pump blood at a slower rate than normal.


According to the standard guidelines, the levels of blood pressure is normal if it is more than 120 over 80 and less than 140 over 90 (120/80-140/90).


People with blood pressure lower than 120/80 are considered normal without being accompanied by symptoms of light-head or dizziness.

According to the statistics provided by the CDC, in the U.S. 29% or 100 million adults have hypertension during 2015–2016 and hypertension prevalence increased with age and was 33.2% among those aged 40–59 and 63.1% among those aged 60 and over.


Honey, the rich golden liquid is a miraculous product made by bees using nectar from flowers.

The liquid is considered one of the healthy food for replacing the use of white sugar and artificial sweetener by many people.

Researchers in the course of finding a natural ingredient for the treatment of high blood pressure investigated the safety and effect of intrapulmonary administration (by inhalation) of 60 % honey solution, 10% dextrose, or distilled water in normal or diabetic subjects.

Twenty-four healthy subjects, 16 patients with type 1 diabetes mellitus and six patients with hypertension were selected to participate in the study.


Twelve healthy subjects were subjected to distilling water inhalation for 10 min, and after one week they received inhalation of honey solution (60% wt/v) for 10 min. Another 12 healthy subjects received inhalation of 10% dextrose for 10 min.

Honey treatment showed a mild reduction of blood pressure compared to no change in another group.

From a time perspective, systolic and diastolic blood pressure was reduced by honey inhalation in hypertensive patients at 60 and 120 min.


After taking into account co and confounders, researchers said, "honey inhalation was safe and effective in reducing...elevated blood pressure in hypertensive patients".

Moreover, in order to obtain more information on honey antihypertensive activity, researchers investigated the aqueous extract obtained from the mixture of the fresh leaf of Persea Americana, stems, and a fresh leaf of Cymbopogon citrus, fruits of Citrus medica, and honey on ethanol and sucrose-induced hypertension in rats.


Rats included in the study were divided into eight groups of 6 rats each and daily treated for 5 weeks. The control group received distilled water (1 mL/kg) while rats of groups 2, 3, and 4 received ethanol 40 degrees (3 g/kg/day), 10% sucrose as drinking water, and the two substances respectively.

The remaining groups received additional sucrose and ethanol, the aqueous extract (50, 100, and 150 mg/kg) or nifedipine (10 mg/kg) respectively.


Group treated with ethanol and sucrose showed a significantly (p < 0.001) increased blood pressure and heart rate compared to distilled water-treated rats.


Chronic treatment of ethanol and sucrose also exerted significantly decreased the activities of antioxidant enzymes produced by the host, observed by the levels of superoxide dismutase (SOD) and catalase (CAT) and elevated levels of oxidative stress observed by the stress marker malondialdehyde (MDA) levels.

However, administration of the aqueous extract or nifedipine prevented all changes caused by chronic ethanol and sucrose, including the hemodynamic, biochemical, oxidative, and histological impairments.


The finding clearly suggested that aqueous extract including honey possesses antihypertensive activity by the improvement of biochemical and oxidative status, through its antioxidant property.

Taken altogether, honey used alone or combined with other herbs may be considered anti-hypertension functional remedies with no side effects, pending the confirmation of a large sample size and multicenter human study.



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional's Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca



Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Intrapulmonary administration of natural honey solution, hyperosmolar dextrose or hypoosmolar distill water to normal individuals and to patients with type-2 diabetes mellitus or hypertension: their effects on blood glucose level, plasma insulin and C-peptide, blood pressure and peaked expiratory flow rate by Al-Waili N1. (PubMed)
(2) Antihypertensive potential of the aqueous extract which combine leaf of Persea americana Mill. (Lauraceae), stems and leaf of Cymbopogon citratus (D.C) Stapf. (Poaceae), fruits of Citrus medical L. (Rutaceae) as well as honey in ethanol and sucrose experimental model by Dzeufiet PD1, Mogueo A, Bilanda DC, Aboubakar BF, Tédong L, Dimo T, Kamtchouing P. (PubMed)

Sunday, July 3, 2022

Tomato Apoptoses Liver Cancer Better Than of Doxorubicin and Camptothecin in Vitro



Cancer is a class of diseases caused by cells growing disorderly and uncontrollably in our bodies.

Liver cancer is a chronic medical condition associated with irregular cell growth in the liver tissues.


The liver is the largest internal organ that only filters out blood from the intestine before passing them to other parts of the body, but also produces bile to aid digestion, build strong cell walls and vitamin D and steroid hormones.


The liver joined with the kidney and skin is considered 3 detoxed organs in the human.


Most common liver cancers are* Hepatocellular carcinoma, is a most common liver cancer accounting, accounting for 75 percent of all cases caused by the DNA alternation of hepatocytes, predominant liver cells.

Epidemiologically, primarily hepatocellular carcinoma has been found to metastasize to the pancreas, intestines, and stomach.


* Cholangiocarcinoma, also known as bile duct cancer, is caused by abnormal cell growth in the small, tube-like bile ducts in the liver, accounting to 10 to 20% of all liver cancer cases.


Out of many prevalent factors that cause the onset of liver cancer, some researchers suggested that the promotion of a high-fat diet over the past few decades may have a strong impact to increase the risk of liver cancer.


Dr. Qiu-Ye Lan, the lead scientist wrote, "Healthy dietary patterns may prevent many chronic diseases and is emphasized by 2015 US dietary guideline, but it remains unclear which dietary patterns may be a benefit to prevention of primary liver cancer (PLC)"


And, "Our findings suggest that the UPDP (an urban prudent dietary pattern (UPDP)) and TCDP (traditional Cantonese dietary pattern (TCDP) )were associated with lower, whereas the MPFP with the higher, risk of PLC".


Tomato is red, edible fruit, genus Solanum, belongings to family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.

In the urgency to discover healthy foods for the treatment of liver cancer, researchers examined the effect of the tomato antiproliferative activities against human colon (HT29) and liver (HepG2) cancer cells.

Application of the tetrasaccharide tomato glycoalkaloid alpha-tomatine, the trisaccharide beta(1)-tomatine, the disaccharide gamma-tomatine, the monosaccharide delta-tomatine, and their common aglycon tomatidine showed better inhibition of liver cancer cell compared to the tested colon cell line.

Additionally, alpha-tomatine isolated from tomato at a concentration of 1 microg/mL demonstrated a greater effect against liver carcinoma cells compared to those of anticancer drugs doxorubicin and camptothecin

Furthermore, alpha-tomatine also inhibited normal human liver HeLa (Chang) cells without inducing any side effects.

Also in vitro, according to the tested assays,
* Alpha-tomatine isolated from green tomatoes induced liver cancer cells death compared to little inhibition of the cells by the three low-tomatine red tomato extracts.


* Alpha-Tomatine from tomato also was highly effective in inhibiting all of the liver cell lines, compared to little cell inhibition of ehydrotomatine, tomatidenol, and tomatidine.



Collectively, the results not only showed the susceptibility to destruction varies with the nature of the alkaloid and plant extract but also how phytochemicals in plants worked synergistically in cancer inhibition.

Dr. Friedman M, the lead scientist said, "These findings extend related observations on the anticarcinogenic potential of glycoalkaloids and suggest that consumers may benefit by eating not only high-lycopene red tomatoes but also green tomatoes containing glycoalkaloids".


Taken altogether, tomato processed with a high amount of lycopene may be considered a dietary supplement for the prevention and treatment of liver cancer, pending to large sample size and multicenter human study.

Intake of lycopene in the form of supplement should be taken with extreme care to prevent overdose and acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca



Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Tomatine-containing green tomato extracts inhibit the growth of human breast, colon, liver, and stomach cancer cells by Friedman M1, Levin CE, Lee SU, Kim HJ, Lee IS, Byun JO, Kozukue N. (PubMed)
(2) Glycoalkaloids and metabolites inhibit the growth of human colon (HT29) and liver(HepG2) cancer cells by Lee KR1, Kozukue N, Han JS, Park JH, Chang EY, Baek EJ, Chang JS, Friedman M. (PubMed)
(3) Dietary patterns and primary liver cancer in Chinese adults: a case-control study by Qiu-Ye Lan,1 Gong-Cheng Liao,1 Rui-Fen Zhou,1 Pei-Yan Chen,1 Xiao-Yan Wang,1Min-Shan Chen,2 Yu-Ming Chen,1 and Hui-Lian Zhu. (PubMed)