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Tuesday, May 31, 2016

The #CurableSmoothie of Blueberry, Tomato and Pineapple for Reduced Risk and Treatment of Membranous Glomerulonephritis

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of Membranous glomerulonephritis
Yield: 2 servings (about 8 ounces each)
1/ 2 cup tomato
1/2 cup pineapple
1 1/2 cups blueberry juice

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of Membranous glomerulonephritis has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Membranous glomerulonephritis is a slowly progressive kidney disease caused by the thickening of part of the glomerular basement membrane as a result of autoimmune injury(1) probably caused by expression of anti-aldose reductase (AR) and anti-manganese superoxide dismutase (SOD2) IgG(6), affecting mostly Caucasian patients between ages of 30 and 50 years.
Recent study led by renowned institutions suggested that Resveratrol  found abundantly may consist strong anti-complement, anti-oxidative, and anti-apoptotic effects in a murine model of membranous nephropathy(2), through attenuated renal Eathological changes in db/db mice model(3).

Ferulic Acid found in tomato may be used as phytochemicals derived from dietary components to combat human diseases, including membranous glomerulonephritis(4). According to the Taipei Medical University, the antioxidant also an Derived Polyphenol from Dang Qui, inhibited the progression of membranous Nephropathy in a Mouse Model, through involved the regulation of oxidative stresses, angiogenic and antiangiogenic factors, and attenuation of Th2 immune response(4)
Melatonin, boosted intake of pineapple, in animal model, exhibited anti expression of anti-inflammatory cytokines (interleukin 10), production of reactive oxygen species and induced apoptotic TUNEL-positive apoptotic cells in the kidney through amelioration of proteinuria and glomerular lesions,...of membranous glomerulonephritis((5).

The smoothie of Blueberry, Tomato and Pineapple may hold a key in further studies in production of effective natural ingredients for prevention and treatment of any type of Membranous glomerulonephritis without inducing adverse effects.

People who are at increased risk of any of Membranous glomerulonephritis, due to family history, weaken immunity... should drink at least one cup daily. People with Membranous glomerulonephritis, should drink no more than 4 servings daily, depending to the digestive toleration.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Rerences
(1) Biologics for the treatment of autoimmune renal diseases by Holdsworth SR1,2, Gan PY1, Kitching AR1,2.(PubMed)
(2) Resby veratrol ameliorates renal damage, increases expression of heme oxygenase-1, and has anti-complement, anti-oxidative, and anti-apoptotic effects in a murine model of membranous nephropathy Wu CC1, Huang YS2, Chen JS3, Huang CF4, Su SL5, Lu KC6, Lin YF7, Chu P3, Lin SH3, Sytwu HK8.(PubMed)
(3) Resveratrol improves oxidative stress and protects against diabetic nephropathy through normalization of Mn-SOD dysfunction in AMPK/SIRT1-independent pathway by Kitada M1, Kume S, Imaizumi N, Koya D.(PubMed)
(4)Ferulic Acid, an Angelica sinensis-Derived Polyphenol, Slows the Progression of Membranous Nephropathy in a Mouse Model by Cheng CW1, Chang WL, Chang LC, Wu CC, Lin YF, Chen JS.(PubMed)(5) Melatonin enhances endogenous heme oxygenase-1 and represses immune responses to ameliorate experimental murine membranous nephropathy by Wu CC1, Lu KC, Lin GJ, Hsieh HY, Chu P, Lin SH, Sytwu HK.(PubMed)
(6) Autoimmunity in membranous nephropathy targets aldose reductase and SOD2 by Prunotto M1, Carnevali ML, Candiano G, Murtas C, Bruschi M, Corradini E, Trivelli A, Magnasco A, Petretto A, Santucci L, Mattei S, Gatti R,Scolari F, Kador P, Allegri L, Ghiggeri GM.(PubMed)

Monday, May 30, 2016

The Smoothie of Spanish, Sweet Potato and Carrot for Prevention and Treatment of Glomerulosclerosis

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of Glomerulosclerosis
Yield: 2 servings (about 8 ounces each)
1  cup sweet potato
1/2  cup carrot
1 cup Spanish drink

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of Glomerulosclerosis has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Glomerulosclerosis is a health conditon of hardening of the glomerulus with function of filterring urine from the blood in the kidney. Recent studies suggested that CoQ10 found abundantly in spinach may benefit patients with Glomerulosclerosis. Defects in coenzyme Q10 (CoQ10) biosynthesis, manifested in patient-derived lymphoblastoid cell lines(3) is associated to focal segmental glomerulosclerosis in children and in adults(2).
According to the Lorestan University of Medical Sciences, Coenzyme Q10 alleviated glomerulosclerosis on the lipid peroxidation and antioxidant enzymes activity in alloxan-induced type 1 diabetic rats(1).

Vitamin E, found abundantly in sweet potato, ameliorated  expression of glomerulosclerosis, restored renal neuronal nitric oxide synthesis (NOS) by suppressing the  oxidative stress in animal model(4)

Retinoic acid, a derivative of vitamin A , found in carrot can revert renal progenitor differentiation and promote podocyte regeneration in progression toward glomerulosclerosis(5).
According to the The First Affiliaionted Hospital of GuangXi Medical University, all-trans retinoic acid (ATRA), a promising therapeutic agent with function mimicked those of vitamin A, exhibited the protective effect against glomerulosclerosis (GS) lesions in rats, similar to renin-angiotensin aldosterone system (RAAS)(6).
Dr. Zhou TB and colleagues at the The First Affiliated Hospital of Guangxi Medical University, said, "(all-trans retinoic acid) ATRA can increase the gelatinases expressions and reduce the accumulation of apoE in glomerulus of GS rats,...."(7).

The effectiveness of Spanish, Sweet Potato and Carrot may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for for Reduced Risk  and treatment of Glomerulosclerosis with little or no adverse effects.
People who are at increased risk of Glomerulosclerosis due to aging, weaken reno function.,..... should drink the smoothie twice a day and people with Glomerulosclerosis should drink as much as they can, depending to the digestive toleration.
Life style and dietary patter change are recommended.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer



References
(1) Amelioration of altered antioxidant enzymes activity and glomerulosclerosis by coenzyme Q10 in alloxan-induced diabetic rats by Ahmadvand H1, Tavafi M, Khosrowbeygi A.(PubMed)
(2) Mitochondrial dysfunction in inherited renal disease and acute kidney injury by Emma F1, Montini G2, Parikh SM3, Salviati L4.(PubMed)
(3) Focal segmental glomerulosclerosis is associated with a PDSS2 haplotype and, independently, with a decreased content of coenzyme Q10 by Gasser DL1, Winkler CA, Peng M, An P, McKenzie LM, Kirk GD, Shi Y, Xie LX, Marbois BN, Clarke CF, Kopp JB.(PubMed)
(4) Vitamin E reduces glomerulosclerosis, restores renal neuronal NOS, and suppresses oxidative stress in the 5/6 nephrectomized rat by Tain YL1, Freshour G, Dikalova A, Griendling K, Baylis C.(PubMed)
(5) Retinoids and glomerular regeneration by Lazzeri E1, Peired AJ2, Lasagni L3, Romagnani P4.(PubMed)
(6) Association of all-trans retinoic acid treatment with the renin-angiotensin aldosterone system expression in glomerulosclerosis rats by Zhou TB1, Wu WF, Qin YH, Yin SS.(PubMed)
(7) All-trans retinoic acid can regulate the expressions of gelatinases and apolipoprotein E inglomerulosclerosis rats by Zhou TB1, Qin YH, Ou C, Lei FY, Su LN, Huang WF, Zhao YJ.(PubMed)

Sunday, May 29, 2016

The Smoothie of Green Tea and Low Fat Milk for Prevention and Treatment of Focal proliferative nephritis

Kyle J. Norton (Scholar, and Master of nutrients) All right reserved
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years

Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Imaging of long term intake of delicious smoothies loved by many with the power of reduced risk and treatment of chronic illness with no one mentions about. In fact, it happens. Epidemiological studies with strong evidences suggested that blueberry oral administration hold a potential with therapeutic values for reduced risk of women who carry the mutation gene and treatment of breast cancer(*).

The curable smoothies are collection of recipes produced from natural sources, including organic fruits and vegetables, and some herbs which have been proven effectively for reduced risk and treatment for diseases and syndromes by scientific research of clinical trials and/or studies.

The finding of foods from natural sources has been a dream of scientists and scholars since ancient time. Socrates Said," Let foods be your medicine and let medicine be your foods". Let all of us all exercise the values of the past wisdom to build a letter living and living health while enjoining these delicious drinks.

The smoothie for Prevention and treatment of Polyuria

Yield: 2 servings (about 8 ounces each)
1 cup low fat milk
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately
Recent studies by some renowned institutions suggested that green tea(1) and low fat milk may be the next generation of ingredient extracted from natural sources for reduced risk and treatment of Focal proliferative nephritis.

Focal proliferative nephritis is a type of glomerulonephritis seen in 20% to 35% of causes of lupus nephritis.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. Its phytochemical (-)-epigallocatechin gallate (EGCG), exhibited prophylactic effects in enhancing the Nrf2 in regulation of antioefxidant signaling pathway and decreasing renal NLRP3 in activation of pro inflammatory pathways(1).

Cholecalciferol (vitamin D3) found abundantly in low fat milk may also benefit patients of g glomerulonephritis induced by systemic lupus(SLE). According to the Universidade Federal de São Paulo-Escola Paulista de Medicina, vitamin D analogs modulated the immune system in prevention of autoimmune diseases in induced kidney inflammation(2).
It is said that vitamin D also involved in the attenuated physiopathology of bone metabolism disturbance in patients with lupus nephritis.

The effectiveness of Green Tea and Low Fat Milk may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for prevention and treatment of Focal proliferative nephritis with little or no adverse effects.

People who are at high risk of Focal proliferative nephritis due to systemic lupus(SLE) and people with Focal proliferative nephritis should drink no more than 4 servings daily, depending to digestive toleration.

Life style and diet pattern change are necessary.


Reference(1) Epigallocatechin-3-gallate prevents lupus nephritis development in mice via enhancing the Nrf2 antioxidant pathway and inhibiting NLRP3 inflammasome activation by Tsai PY1, Ka SM, Chang JM, Chen HC, Shui HA, Li CY, Hua KF, Chang WL, Huang JJ, Yang SS, Chen A.(PubMed)
(2) [Immune modulation by vitamin D analogs in the prevention of autoimmune diseases].[Article in Dutch] by Bouillon R1, Verstuyf A, Branisteanu D, Waer M, Mathieu C.(PubMed)
(3) Bone disease in newly diagnosed lupus nephritis patients by Resende AL1, dos Reis LM1, Dias CB1, Custódio MR1, Jorgetti V1, Woronik V1.(PubMed)

Saturday, May 28, 2016

Women Health: The Smoothie of Orange, Yogurt, Ginger herbal Tea for Reduced risk and treatment of Thrush in Pregnancy



    Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
    Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
    Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
    Nominated for shorty award over last 4 years
    Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

    The Incredible and Effective smoothie for Prevention and treatment of Thrush caused by fungus infection
    Yield: 2 servings (about 8 ounces each)
    1 cup orange
    1/2 cup yogurt
    1 cup ginger herbal tea

    1. Place all ingredients in a blender and puree about 1 minute
    2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
    3. Serve immediately
    Thrush (oropharyngeal candidiasis) is a medical condition caused by fungus Candida albicans. Thrush in pregnancy is a condition associated to the infection of the vagina caused by fungus Candida albicans. During pregnancy, as a result of hormone change, cervical fluid has become abundant and thicker to prevent the sperm from entering the cervical canal, leading to high amount of glycogen in the vagina that promotes the growth of bacteria, causing thrush in some women.
    Candida albicans are members of a large group of micro organism whose cells contain complex structures enclosed within the membranes, including yeast, fungi, and mold that live among the gut flora in the human mouth and gastrointestinal tract. In fact, under normal circumstances, Candida albicans that do not cause harmful effects, but overgrowth results in candidiasis(1)

    The finding of a natural source for reduced risk and treatment of Thrush to replace the conventional medicine has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

    Yogurt, make from whole milk may consist a powerful ingredient for prevention and treatment of Vaginal yeast infection as its promote the suppression of C. albicans growth through Lactobacillus colonization the in the reproductive tract(2).
    The study of the Central Emek Hospital, Afula, Israel, insisted, "daily ingestion of 150 mL of yogurt, enriched with live L acidophilus, was associated with an increased prevalence of colonization of the rectum and vagina by the bacteria, and this ingestion of yogurt may have reduced episodes of BV."(3).
    Vitamin C found abundantly in orange, a water soluble vitamin, as free radical scavengers and regenerated oxidized vitamin E for immune support may be a potential ingredient for treatment of vaginal yeast infection(4).
    Feminella Vagi C, a commercial product of Vitamin C (Ascorbic Acid) exhibited anti bacterial vaginosis (BV) and/or mycotic infection activity when used conjunction with Nifuratel, Nistatin)(5) leading to higher percentage of clinically recovery (86.7% vs 84.6%), better microbiological cleaning (86.7% vs 82.1%) and longer effect of treatment.

    Ginger (Zingiber officinale) or ginger root is the genus Zingiber, belongings to the family Zingiberaceae, native to Tamil, used in traditional and Chinese medicine to treat morning sickness, gastroparesis, constipation,...etc. According to the Teikyo University Institute of Medical Mycology, ginger essential oils, and particularly those from seed and air-dried rhizomes, had potent inhibitory activity, particular the 6]-shogaol constituent(6).
    Dr. Giriraju A and Dr. Yunus GY. said, " 10% ethanolic ginger extract showed: (a) Maximum zone of inhibition of 8 mm, 14 mm, and 11 mm against S. mutans, C. albicans, and E. faecalis respectively. (b) MIC of 1.25%, 2.5%, and 2.5% against S. mutans, C. albicans, and E. faecalis respectively"(7).
    Interestingly, the Institute of Veterinary Sciences University Ibn-KhadounTiaret, study suggested that use of ginger starch may allow honey benefit in constituted an alternative way against the resistance to antifungal agents(8).


    The effectiveness of Orange, Yogurt,  and Ginger may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for for Reduced Risk and treatment of Thrush with little or no adverse effects.

    Women who are at increased risk of Thrush(such as pregnancy) may drink at least one serving daily and women with vaginal yeast infection may drink as much as they can, depending to the digestive toleration.
    Life style and dietary patter change are recommended.

    All Forms of Arthritis are Curable
    You Can Eliminate Osteoarthritis
    By addressing the Underlying Causes through Clinical Trials and Studies


    Ovarian Cysts And PCOS Elimination
    Holistic System In Existence That Will Show You How To
    Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


    Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer


    References
    (1) The Reader Guide To Cure Candidiasis: Testing Candidiasis by Kyle J. Norton
    (2) Utility of the oestrogen-dependent vaginal candidosis murine model in evaluating the efficacy of various therapies against vaginal Candida albicans infection by Hamad M1, Muta'eb E, Abu-Shaqra Q, Fraij A, Abu-Elteen K, Yasin SR.(PubMed)
    (3) Ingestion of yogurt containing Lactobacillus acidophilus compared with pasteurized yogurt as prophylaxis for recurrent candidal vaginitis and bacterial vaginosis by Shalev E1, Battino S, Weiner E, Colodner R, Keness Y.(PubMed)
    (4) Vulvovaginitis: screening for and management of trichomoniasis, vulvovaginal candidiasis, and bacterial vaginosis by van Schalkwyk J1, Yudin MH2; Infectious Disease Committee, Yudin MH2, Allen V3, Bouchard C4, Boucher M5, Boucoiran I1, Caddy S6, Castillo E6, Kennedy VL2, Money DM1, Murphy K2, Ogilvie G1, Paquet C7, van Schalkwy JK1; Society of Obstetricians and Gynaecologists of Canada.(PubMed)
    (5) [Multipurpose treatment of vaginal infections].[Article in Bulgarian] by Nikolov A, Masseva A, Shopova E, Georgiev S.(PubMed)
    (6) Anti-Candida and radical scavenging activities of essential oils and oleoresins of Zingiber officinale Roscoe and essential oils of other plants belonging to the family Zingiberaceae by Takahashi M1, Inouye S, Abe S.(PubMed)
    (7) Assessment of antimicrobial potential of 10% ginger extract against Streptococcus mutans, Candida albicans, and Enterococcus faecalis: an in vitro study by Giriraju A1, Yunus GY.(PubMed)
    (9) Additive potential of ginger starch on antifungal potency of honey against Candida albicans by Moussa A1, Noureddine D, Hammoudi SM, Saad A, Bourabeh A, Houari H(PubMed)

Thursday, May 26, 2016

Women Health: The Smoothie of Alfalfa Tea and Flax Seed for Delaying Symptom of Breast Ptosis Due to Aging

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The finding of a natural source for treatment of female breast ptosis has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Female breast ptosis is a natural occurring female breast sagging due to aging in reduced production of estrogen hormone.

The smoothie for delay Menopausal induction of  female breast ptosis due to aging
Yield: 2 servings (about 8 ounces each)
1 1/4 cups alfalfa tea (Make from 2 grams of dried alfalfa leave and sprout, and a cup of hot water lipped for 5 minutes, and let cool to room temperature. You can buy them at any health food store)
1/4 cup flax seed
1/2 cup of rice milk

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding the natural ingredients for treatment of vasomotor symptoms, including breast ptosis  is considered as a dream of many scientist to replace the long term usage adverse effect of conventional medicine.
Unfortunately, many compounds found effective in initial studying failed to confirm the potential in large sample size and multi center.

Menopause is a condition in which a woman is in the transition stage of permanent cessation of the ovaries functions in egg production because of less production of estrogen and progesterone,signalling the end of the reproductive phrase a woman's life. In menopause, menstruation has become irregular and slowly stop overtime, but in some women, menstrual flow comes to a sudden halt.
Isoflavones found in legume, such as alfalfa leaf and sprout processed alleviating vasomotor episodes, attenuating bone loss, and stimulating vaginal epithelial maturation,. according to the joint study lead by The Chiang Mai University(1).

Dr.Sobenin IA and researcher at the Russian Cardiology Research and Production Complex, said, "Phytoestrogens are often considered as a possible alternative to hormone replacement therapy, since they are believed to alleviate some symptoms of menopause, such as, therosclerosis and atherosclerosis-related diseases through multiple mechanisms"(2).
In Fact, Phytoestrogens can play an important role in symptoms of menopause including fatigue, insomnia, problems with concentrations and depression symptoms and on women organism during menopausal period(3).


Levels of serotonin found abundantly in flax seed, is associated to reduced risk, frequency and severity of vasomotor symptoms in menopausal women(4). According to the Massachusetts General Hospital, serotonin-norepinephrine reuptake inhibitor duloxetine significant improve dpression, vasomotor symptoms, sleep, anxiety, and pain after 8 weeks(5).

Dr. Joffe H and the research team at the joint study lead Harvard Medical School, low-dose oral estradiol and venlafaxine(serotonin-norepinephrine reuptake inhibitor ) are effective treatments for VMS in women during midlife(6).

Another selective serotonin reuptake inhibitor, escitalopram, also alleviated the frequency, severity, and bother of menopausal hot flashes in the study of 205 women (95 African American; 102 white; 8 other) between July 2009 and June 2010.(7).

The combination of Alfalfa tea and Flax seed smoothie may hold a key in further studies in production of an effective natural ingredients for prevention and treatment of menopausal symptoms including breast ptosis without inducing adverse effects. Menopausal women should drink as much as they can, depending to the digestive toleration.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


References
(1) Short-Term Isoflavone Intervention in the Treatment of Severe Vasomotor Symptoms after Surgical Menopause: A Case Report and Literature Review by Teekachunhatean S1, Mattawanon N2, Khunamornpong S3.(PubMed)
(2) Phytoestrogen-Rich Dietary Supplements in Anti-Atherosclerotic Therapy in Postmenopausal Women by Sobenin IA1, Myasoedova VA, Orekhov AN.(PubMed)
(3) [Phytoestrogens--whether can they be an alternative to hormone replacement therapy for women during menopause period?].[Article in Polish] by Dittfeld A, Koszowska A, Brończyk AP, Nowak J, Gwizdek K, Zubelewicz-Szkodzińska B.(PubMed)
(4) Methods for the design of vasomotor symptom trials: the menopausal strategies: finding lasting answers to symptoms and health network by Newton KM1, Carpenter JS, Guthrie KA, Anderson GL, Caan B, Cohen LS, Ensrud KE, Freeman EW, Joffe H, Sternfeld B, Reed SD,Sherman S, Sammel MD, Kroenke K, Larson JC, Lacroix AZ.(PubMed)
(5) Treatment of depression and menopause-related symptoms with the serotonin-norepinephrine reuptake inhibitor duloxetine. by Joffe H1, Soares CN, Petrillo LF, Viguera AC, Somley BL, Koch JK, Cohen LS.(PubMed)
(6) Low-dose estradiol and the serotonin-norepinephrine reuptake inhibitor venlafaxine forvasomotor symptoms: a randomized clinical trial by Joffe H1, Guthrie KA2, LaCroix AZ2, Reed SD3, Ensrud KE4, Manson JE5, Newton KM6, Freeman EW7, Anderson GL2, Larson JC2, Hunt J2,Shifren J8, Rexrode KM5, Caan B9, Sternfeld B9, Carpenter JS10, Cohen L8(PubMed)
(7) Efficacy of escitalopram for hot flashes in healthy menopausal women: a randomized controlled trial. by Freeman EW1, Guthrie KA, Caan B, Sternfeld B, Cohen LS, Joffe H, Carpenter JS, Anderson GL, Larson JC, Ensrud KE, Reed SD, Newton KM, Sherman S, Sammel MD, LaCroix AZ.(PubMed)

Wednesday, May 25, 2016

The smoothie of celery, apple and green tea for Hypertensive complication caused by Nutcracker syndrome


Kyle J. Norton(Scholar), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Nutcracker syndrome is a vascular compression of the left renal vein between the superior mesenteric artery (SMA) and aorta, causing increased blood pressure inducing rupture of thin-walled veins to cause accumulation of haematuria. Surgical treatment may be the best option for patients with the syndrome(14)(15).
To reduce the complication of hypertension in induction of accumulation of haematuria, the following smoothie can be helpful.


Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood. high blood pressure means raising pressure in your heart. If your blood pressure stays high over time it can damage the body in many ways.
Blood pressure medications have undoubtedly prevented many deaths from heart disease in the past 30 years, but also induced many irreversible adverse effects, including kidney damage.

The smoothie for people with Hypertensive complication caused by Nutcracker syndrome
Yield: 2 servings (about 8 ounces each)
3/4 cup celery
3/4 cup of apple with peel
1 cup green tea drink 1 cup green tea drink (Make from 4 grams(2 tea bags) of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and set aside for cooling to room temperature)

1. Place the celery, apple with peels, green tea, in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

Diet rich in fruits and vegetable and reduced intake of red meat, saturated fat and trans fat has shown to attenuated risk of hypertension(1). Recent study showed that celery(2) intake used conjunction with berries(3) and green tea(4) may be the potential drink for prevention and treatment of hypertension.

Celery is a species of Apium graveolens, belongings to the family Apiaceae, cultivated all around the globe as a vegetable. According to Chronic administration of hexanic, methanolic, and aqueous-ethanolic extracts of celery seed effectively exhibited an antihypertensive activity in chronic treatment of elevated BP in tested animals(5).

Dr. Dianat M and the research team at the Ahvaz Jundishapur University of Medical Sciences said," hydro-alcoholic celery leaf extract on systolic blood pressure (SBP), heart rate (HR) and lipid profile in animals' model of hypertension induced by fructose"(6)

3‑n‑butylphthalide (NBP), an phytochemical found in celery seed used in traditional Chinese medicine exhibited significantly antihypertensive and attenuated progression of hypertensive effects through decreased oxidative stress and the expression of pro‑inflammatory cytokines(7).
Apple is the pomaceous fruit of the apple tree, a species of the rose family Rosaceae. It is one of the most widely cultivated tree fruits. With phytochemical flavonoids, apple and its peel inhibited angiotensin converting enzyme (ACE) in promoted the development of high blood pressure, Dr Balasuriya N and Dr. Rupasinghe HP. Suggested(8)According to the Mount Sinai School of Medicine, "Flavonoid (found abundantly in fruits and vegetable)(10) intake has been inversely associated with mortality from coronary heart disease and stroke,..... Lowering blood pressure through increased dietary consumption of dietary antioxidants(such as flavonoid) may decrease the rate of end-organ damage that is secondary to hypertension"(9).

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate.

Epigallocatechin-3-O-gallate (EGCG), the main polyphenol presence in green tea is best known for its antioxidant and anti inflammatory effect. In animal model, the phytochemical exhibited anti hypertensive and progressive activity through reduction of oxidative stress in paraventricular nucleus of hypothalamus (PVN), the Xi'an Jiaotong University Health Science Center study showed(11).

Dr. Yarmolinsky J and the research team at the Federal University of Rio Grande do Sul, suggested that, intake of tea are shown to reduce blood pressure in individuals within prehypertensive and hypertensive ranges in the review of all relevant studies published from 1946 to September 27, 2013.(12).

Furthermore, green tea extract (GTE) inhibited the oxidative stress and ingiotensin (Ang) II induces endothelial dysfunction (ED) causes of hypertension through scavenging of superoxide anion generation, the University of Padova, insisted(13).

People who are at increased risk of hypertension caused by Nutcracker syndrome should drink the juices at least 3 times a day, depending to digestive toleration.
Change of life style and diet pattern are also recommended.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


References

(1) Fruit and Vegetable Consumption and the Incidence of Hypertension in Three Prospective Cohort Studies by Borgi L1, Muraki I2, Satija A2, Willett WC2, Rimm EB2, Forman JP2.(PubMed)
(2) The effect of hydro-alcoholic celery (Apiumgraveolens) leaf extract on cardiovascular parameters and lipid profile in animal model of hypertension induced by fructose by Dianat M1, Veisi A1, Ahangarpour A1, Fathi Moghaddam H1.(PubMed)
(3) Flavonoids from fruit and vegetables: a focus on cardiovascular risk factors by Toh JY1, Tan VM, Lim PC, Lim ST, Chong MF.(PubMed)
(4) Decaffeinated green tea extract improves hypertension and insulin resistance in a rat model of metabolic syndrome by Ihm SH1, Jang SW, Kim OR, Chang K, Oak MH, Lee JO, Lim DY, Kim JH.(PubMed)
(5) Antihypertensive effect of celery seed on rat blood pressure in chronic administration by Moghadam MH1, Imenshahidi M, Mohajeri SA.(PubMed)
(6) The effect of hydro-alcoholic celery (Apiumgraveolens) leaf extract on cardiovascular parameters and lipid profile in animal model of hypertension induced by fructose by Dianat M1, Veisi A1, Ahangarpour A1, Fathi Moghaddam H1.(PubMed)
(7) Protective effect of 3-n-butylphthalide against hypertensive nephropathy in spontaneously hypertensive rats by Zhu J1, Zhang Y1, Yang C1.(PubMed)
(8) Antihypertensive properties of flavonoid-rich apple peel extract by Balasuriya N1, Rupasinghe HP.(PubMed)
(9) Dietary flavonoids and hypertension: is there a link? by Moline J1, Bukharovich IF, Wolff MS, Phillips R.(PubMed)
(10) Antihypertensive effects of the flavonoid quercetin by Perez-Vizcaino F1, Duarte J, Jimenez R, Santos-Buelga C, Osuna A.(PubMed)
(11) Paraventricular Nucleus Infusion of Epigallocatechin-3-O-Gallate Improves Renovascular Hypertension by Yi QY1, Qi J, Yu XJ, Li HB, Zhang Y, Su Q, Shi T, Zhang DM, Guo J, Feng ZP, Wang ML, Zhu GQ, Liu JJ, Shi XL, Kang YM.(PubMed)
(12) Effect of tea on blood pressure for secondary prevention of cardiovascular disease: a systematic review and meta-analysis of randomized controlled trials by Yarmolinsky J1, Gon G2, Edwards P2.(PubMed)
(13) Prevention of hypertension, cardiovascular damage and endothelial dysfunction with green tea extracts by Antonello M1, Montemurro D, Bolognesi M, Di Pascoli M, Piva A, Grego F, Sticchi D, Giuliani L, Garbisa S, Rossi GP.(PubMed)
(14) Surgical treatment of posterior nutcracker syndrome presented with hyperaldosteronism by Deser SB1, Onem K2, Demirag MK3, Buyukalpelli R2.(PubMed)
(15) Laparoscopic Extravascular Stent Placement for Nutcracker Syndrome: A Report of 13 Cases by Wang SZ1, Zhang WX1, Meng QJ1, Zhang XP1, Wei JX1, Qiao BP1.(PubMed)

The Smoothie for Prevention and Treatment of Cardiorenal syndrome (The Co-existed Cardiovascular disease and Kidney disease)

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Cardiorenal syndrome is a term of interrelated of kidney and cardiovascular. As one disease of 
one organ can induce dysfunction of the other. The coexisting CVD and kidney disease or 'cardiorenal syndrome (CRS)' have a synergistic adverse clinical outcomes.

The smoothie for prevention and treatment of  Kidney disease induced Cardiovascular disease in Cardiorenal syndrome
Yield: 2 servings (about 8 ounces each)

1/2 cup olive
1 cup cooked sweet potato
1 cup organic grape juice

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately


The finding of a natural source for treatment of Kidney disease (induced Cardiovascular disease) in Cardiorenal syndrome has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Recent studies back by well known institutions proposed, Cooked Sweet Potato, Olive and Grape Juice may be the next generation of natural ingredients for prevention and treatment of Kidney disease (induced Cardiovascular disease) in Cardiorenal syndrome

Chronic Kidney Diseases(CKD) in in Autosomal recessive polycystic kidney disease is a progressive loss of kidney function over period longer than 3 months through different stages, deepening to the GFR (Glomerular Filtration Rate). According to the Tri-Service General Hospital, Excessive oxidative stress increased oxidative nucleicacid damage and exagerated the development of complication of Chronic Kidney Diseases(1).

The Anti-Odxidant Therapy in Chronic Renal Insufficiency (ATIC) study suggested, combination of pravastatin, vitamin E, and homocysteine treatment in 18 months together with hypertension controlled  effectively attenuated expression of Chronic Kidney Diseases(CKD) through reduced oxidative stress against renal function(2).Vitamin E-coated membranes (VECMs) consist of a multilayer membrane with liposoluble vitamin E, used in dialysis significantly improved Hb levels and lower rHuEpo requirements in chronic HD patients(3).Dr. Rashid Khan M and colleagues insisted, vitamin E significantly reduced dyslipidemia and inhibited the development of CRD caused by atherogenic factors after six weeks. particular in hypolipidemic and nephroprotective activity against free radical-related diseases(4).

N-3 fatty acids found abundantly in olive may also contribute to the potential benefits of dietary fat
modification in CKD patients, according to the Karolinska Institutet(5).
Dr. Lee SM and Dr. An WS., professors at the Seoul National University Hospital, insisted, intake of Omega 3 fatty acid exhibited cardioprotective effects in chronic kidney disease, the main cause of death, through attenuated inflammation, dyslipidemia, malnutrition, atherosclerosis, and vascular calcification(6).
Dr. Friedman AN said, " Long-chain polyunsaturated omega-3 fatty acids (n-3 PUFA), which are obtained primarily from dietary sources such as coldwater fish, have diverse and potent mediating effects on the immune, inflammatory, and metabolic pathways, signal transduction, and cell membrane physiology" and "In the meantime, the current American Heart Association n-3 PUFA intake guidelines can be applied to CKD patients"(7).

Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in grape and blueberry, may also benefit in attenuated complications and treatment of Chronic Kidney Diseases(CKD), through its inflammation and oxidative stress modulation (8).
According to the joint study led by the The Catholic University of Korea, Bucheon, resveratrol expressed renoprotective effects by activating NRF2 signaling against against oxidative or electrophilic stress(9).Furthermore by suppressing the pro inflammatory cytokines, consumption of white wine and olive oil, significantly reduced plasma markers of chronic inflammation in CKD patients(10).

The effectiveness of Cooked Sweet Potato, Olive and Grape Juice may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for reduced risk, complications and treatment of Kidney disease (induced Cardiovascular disease) in Cardiorenal syndromewith little or no adverse effects.

People who are at high risk of Kidney disease (induced Cardiovascular disease) in Cardiorenal syndrome should drink no more than 4 servings daily, depending to digestive toleration.
Life style and diet pattern change are necessary.


The smoothie for prevention and Treatment of Cardiovascular disease induced Kidney disease in Cardiorenal syndrome

Yield: 2 serving (about 8 ounce each)
1 cup Blueberry
1/4 cup avocado
1/4 cup raw flax seed
1 cup of rice milk

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The dream of finding the natural ingredient for prevention and treatment of heart disease with adverse effects in replacement of conventional medication has not been abated. Some ingredients have to discard due to it can achieve the same potent results in human trials.
Beside cancer, heart disease kills more than 2,000 Americans everyday. Approximately 60 million Americans have heart disease.
Scientist community may have found the smoothie(combined ingredients of green tea) with potential and therapeutic value for reduced risk and treatment of heart disease without adverse effects.


Blueberry is a flower plant, belonging to the family Eriaceae and native to Northern America, cultivated all over the world in suitable climate for its health benefits and commercial profits. Recent study suggested that blueberry may have a potential to become a pharmaceutical ingredient for treatment of heart disease(1) due to its phytochemical procyanidin composition and total anthocyanin contents(10).

According to the National Institutes of Health, blueberry enriched diet (BD) has exhibited protective effects on myocardium from induced ischemic damage and demonstrated the potential to attenuate the development of post MI chronic heart failure(11).

Furthermore, Dr. Ahmet I and the research team at the same institution said" a blueberry-enriched diet has positive effects on the course of CHF and thus warrants consideration for clinical evaluation"(12).

Blueberry anthocyanins-enriched extracts (BAE) inprove heart function by attenuated mean arterial blood pressure, heart rate and activities of heart enzymes, improved cardiac dysfunction, left ventricular hypertrophy and fibrosis, through decreased inflammatory cytokines expression, ameliorated oxidative stress,...(13) on cyclophosphamide (CTX)-induced cardiac injury.

Avocados are a commercially valuable fruit and are cultivated in tropical climates throughout the world, it is a green-skinned, pear-shaped fruit that ripens after harvesting and native to the Caribbean, Mexico, South America and Central America, belonging to the flowering plant family Lauraceae.

According to the University of KwaZulu-Natal, intake of acovado leaf extract (PAE) used as a natural supplementary remedy showed to inhibit hypertension and certain cases of cardiac dysfunctions in some rural Africa communities(14).
In animal model, combination of aqueous extract containing leaf of Persea americana Mill. (Lauraceae), stems and leaf of Cymbopogon citratus (D.C) Stapf. (Poaceae), fruits of Citrus medical L. (Rutaceae) exhibited antihypertensive activity against ethanol and sucrose induced hypertension in rats by the improvement of biochemical and oxidative status(15).
Furthermore, Dr. Rodriguez-Sanchez D and the research team at the Tecnológico de Monterrey, avocado due to its acetogenin compounds, inhibited platelet aggregation with a potential preventive effect on thrombus formation, such as those that occur in ischaemic disease(16).

Flax seed is native to the region of the eastern Mediterranean to India and also known as common flax or linseed. n-3 polyunsaturated fatty acids (PUFAs), the main ingredient found in flax seed exhibit cardio protective effects through defending cardiomyocytes against the cell signalling protein TNF in pro-apoptotic action and preventing cardiac degenerative diseases(17).
According to the University of Manitoba, flax seed also retarded the progression of atherosclerotic plaques resulting in a significant ≈40% reduction in plaque formation(18).
In New Zealand White rabbits study, flaxseed supplementation effectively limit cholesterol-induced atherogenesis and abnormalities in endothelial-dependent vasorelaxation(19).

People who are at increased of Cardiovascular disease due to family history, obesity.....should drink at least one serving daily and people with Cardiovascular disease should drink no more than 4 serving a day, depending to digestive toleration.
Change of  life style and diet pattern are also recommended.


All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


References
(1) Oxidative stress and nucleic acid oxidation in patients with chronic kidney disease by Sung CC1, Hsu YC, Chen CC, Lin YF, Wu CC.(PubMed)
(2) Effect of a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on carotid intima-media thickness, endothelial function, and renal function in patients with mild to moderate chronic kidney disease: results from the Anti-Oxidant Therapy in Chronic Renal Insufficiency (ATIC) Study by Nanayakkara PW1, van Guldener C, ter Wee PM, Scheffer PG, van Ittersum FJ, Twisk JW, Teerlink T, van Dorp W, Stehouwer CD.(PubMed)
(3) Effect of vitamin E-coated dialysis membranes on anemia in patients with chronic kidney disease: an Italian multicenter study by Cruz DN1, De Cal M, Garzotto F, Brendolan A, Nalesso D, Corradi V, Ronco C.(PubMed)
(4) Tocotrienols have a nephroprotective action against lipid-induced chronic renal dysfunction in rats by Rashid Khan M1, Ahsan H, Siddiqui S, Siddiqui WA.(PubMed)
(5) Dietary fat modification in patients with chronic kidney disease: n-3 fatty acids and beyond by Huang X1, Lindholm B, Stenvinkel P, Carrero JJ.(PubMed)
(6) Cardioprotective effects of ω -3 PUFAs in chronic kidney disease. by Lee SM1, An WS.(PubMed)
(7) Omega-3 fatty acid supplementation in advanced kidney disease by Friedman AN1.(PubMed)
(8) Resveratrol: why is it a promising therapy for chronic kidney disease patients?by Saldanha JF1, Leal Vde O2, Stenvinkel P3, Carraro-Eduardo JC4, Mafra D1.(PubMed)
(9) Effect of redox modulating NRF2 activators on chronic kidney disease.by Choi BH1, Kang KS2, Kwak MK3.(PubMed)
References
(10) Influence of extrusion processing on procyanidin composition and total anthocyanin contents of blueberrypomace by Khanal RC1, Howard LR, Brownmiller CR, Prior RL.(PubMed)
(11) Blueberry-enriched diet protects rat heart from ischemic damage by Ahmet I1, Spangler E, Shukitt-Hale B, Juhaszova M, Sollott SJ, Joseph JA, Ingram DK, Talan M.(PubMed)
(12) Survival and cardioprotective benefits of long-term blueberry enriched diet in dilated cardiomyopathy following myocardial infarction in rats by Ahmet I1, Spangler E, Shukitt-Hale B, Joseph JA, Ingram DK, Talan M.(PubMed)
(13) Blueberry Anthocyanins-Enriched Extracts Attenuate Cyclophosphamide-Induced Cardiac Injury. by Liu Y1, Tan D2, Shi L1, Liu X1, Zhang Y1, Tong C1, Song D2, Hou M1.(PubMed)
(14) Cardiovascular effects of Persea americana Mill (Lauraceae) (avocado) aqueous leaf extract in experimental animals by Ojewole JA1, Kamadyaapa DR, Gondwe MM, Moodley K, Musabayane CT.(PubMed)
(15) Antihypertensive potential of the aqueous extract which combine leaf of Persea americana Mill. (Lauraceae), stems and leaf of Cymbopogon citratus (D.C) Stapf. (Poaceae), fruits of Citrus medical L. (Rutaceae) as well as honey in ethanol and sucrose experimental model. by Dzeufiet PD1, Mogueo A, Bilanda DC, Aboubakar BF, Tédong L, Dimo T, Kamtchouing P.(PubMed)
(16) Isolation and chemical identification of lipid derivatives from avocado (Persea americana) pulp with antiplatelet and antithrombotic activities by Rodriguez-Sanchez DG1, Flores-García M, Silva-Platas C, Rizzo S, Torre-Amione G, De la Peña-Diaz A, Hernández-Brenes C, García-Rivas G.(PubMed)
(17) A diet supplemented with ALA-rich flaxseed prevents cardiomyocyte apoptosis by regulating caveolin-3 expression by Carotenuto F1, Minieri M, Monego G, Fiaccavento R, Bertoni A, Sinigaglia F, Vecchini A, Carosella L, Di Nardo P.(PubMed)
(18) Effects of dietary flaxseed on atherosclerotic plaque regression by Francis AA1, Deniset JF, Austria JA, LaValleé RK, Maddaford GG, Hedley TE, Dibrov E, Pierce GN.(PubMed)
(19) Effects of dietary flaxseed on vascular contractile function and atherosclerosis during prolonged hypercholesterolemia in rabbits by Dupasquier CM1, Weber AM, Ander BP, Rampersad PP, Steigerwald S, Wigle JT, Mitchell RW, Kroeger EA, Gilchrist JS, Moghadasian MM, Lukas A, Pierce GN.(PubMed)

Tuesday, May 24, 2016

The Curable smoothie of Green Tea, Grape and Ginger for Reduced Risk and Treatment of Nephritis

Kyle J. Norton(Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and treatment of Nephritis

Yield: 2 serving (about 8 ounce each)
3/4 cup pomegranate
3/4 cup of cherries
1 cup green tea drink 1 cup green tea drink (Make from 4 grams(2 tea bags) of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and set aside for cooling to room temperature)


1. Place the pomegranate, cherries, and green tea, in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

Nephritis is a condition of inflammation of kidneys

Many suggestions that pumpkin seeds used in conjunction with green tea may be a potential combination for reduced risk and treatment of Nephritis. due to the phytochemicals of catechins in green tea(1). 
Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years used in traditional Chinese medicien for treatment of variety of diseases, including cancers and heart diseases.
According to the Graduate Institute of Medical Sciences, National Defense Medical Center, phytochemical Epigallocatechin-3-gallate isolated from green tea inhibited nephritis through it relation of proinflammatory cytokines and enhanced antioxidant signaling pathway(1).
The major chemical constituent EGCG also prevented cisplatin-induced nephrotoxicity and reduced due to over expression of NF-kappaB, the inflammatory pathway(2).
The Shanghai Tenth People's Hospital of Tongji University study in the evaluation of the effects of EGCG in animal with glomerulonephritis said, " EGCG pretreatment period. Importantly, mortality and renal dysfunction were significantly attenuated even when the polyphenol treatment was initiated 1 week after the onset of GN. Thus, EGCG reversed the progression of immune-mediated GN in mice by targeting redox and inflammatory pathways"(3).

Resveratrol, found abundantly in grape, blueberry and peanut  is a phytochemical in the class of Stilbenoids, exhibited anti inflammatory diseases, including the Nephritis, through attenuated on 
proteinuria, hypoalbuminemia and hyperlipidemia(4). According to University of Yamanashi, the phytochemicals also expressed inhibition of pro inflammatory cytokines in the NF-kappaB pathway via antioxidant and oxidative stress effects(5).

Ginger (Zingiber officinale) or ginger root is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil. It has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc. According to the Dr. Nassan M and Dr. Mohamed EH ginger expressed strongly antimicrobial and immuno modulating effects on certain pathogenic microorganisms in ameliorated acute hematogenous pyelonephritis in animal model(6).

The effectiveness of Green Tea, Grape and Ginger may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for Reduced Risk of Nephritis with little or no adverse effects.

People who are at increased risk of Nephritis due to family history, weaken immunity.... should drink 1 serving daily and people with Nephritis should drink as much as they can, depending to digestive toleration.
Life style and diet pattern changed are recommended

All Forms of Arthritis are Curable

Ovarian Cysts And PCOS Elimination


References
(1) Epigallocatechin-3-gallate prevents lupus nephritis development in mice via enhancing the Nrf2 antioxidant pathway and inhibiting NLRP3 inflammasome activation by Tsai PY1, Ka SM, Chang JM, Chen HC, Shui HA, Li CY, Hua KF, Chang WL, Huang JJ, Yang SS, Chen A.(PubMed)
(2) Epigallocatechin-3-gallate activates Nrf2/HO-1 signaling pathway in cisplatin-induced nephrotoxicity in rats by Sahin K1, Tuzcu M, Gencoglu H, Dogukan A, Timurkan M, Sahin N, Aslan A, Kucuk O.(PubMed)
(3) The green tea polyphenol (-)-epigallocatechin-3-gallate ameliorates experimental immune-mediated glomerulonephritis by Peng A1, Ye T, Rakheja D, Tu Y, Wang T, Du Y, Zhou JK, Vaziri ND, Hu Z, Mohan C, Zhou XJ.(PubMed)
(4) Inhibitory effect of resveratrol on proteinuria, hypoalbuminemia and hyperlipidemia in nephritic rats by Nihei T1, Miura Y, Yagasaki K.(PubMed)
(5) Enhancement of NF-kappaB activity by resveratrol in cytokine-exposed mesangial cells by Uchida Y1, Yamazaki H, Watanabe S, Hayakawa K, Meng Y, Hiramatsu N, Kasai A, Yamauchi K, Yao J, Kitamura M.(PubMed)
(6) Immunopathological and antimicrobial effect of black pepper, ginger and thyme extracts on experimental model of acute hematogenous pyelonephritis in albino rats by Nassan MA1, Mohamed EH2.(PubMed)

Monday, May 23, 2016

The Delicious Smoothie of Green Tea, Aloe Vera juice and Grape for Prevention and Treatment of Pyoderma gangrenosum

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of Pyoderma gangrenosum
Yield: 2 servings (about 8 ounces each)
1 1/2 cups grape
1/2 cup Aloe Vera juice
1/2 cup green tea drink (Make from 2 grams of green tea and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of  pyoderma gangrenosum has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Pyoderma gangrenosum, a rare inflammatory skin disorder causes death of the skin tissues induced the development of large, painful sores (ulcers) to your skin, most often on your legs.
According to the University of Louisville, licorice, green tea, pomegranate, turmeric may be sued for treatment of pyoderma gangrenosum, due to its powerful anti inflammatory effect(1).
Dr. Wu J said, "active ingredients, anti-inflammatory properties, clinical effects, and therapeutic potential(rosacea, atopic dermatitis, sensitive and irritated skin, drug-induced skin eruptions, and psoriasis) of colloidal oatmeal, feverfew, licorice, aloe vera, chamomile, and turmeric"(2).

Recent studies by some renowned institutions suggested that green tea(3), Aloe Vera juice(7) and grape(5) may be the next generation of ingredient extracted from natural sources for reduced risk and treatment of pyoderma gangrenosum.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. 
Green tea epigallocatechin gallate (EGCG), a flavonoid belongings to catechins exhibited potent antioxidant and anti-inflammatory diseases, including Pyoderma gangrenosum(1), according to the joint study lead by Federal University of Mato Grosso (UFMT).

Pu-erh tea, made from the leaves of Camellia sinensis, also possessed activities beneficial for human health, including anti-inflammatory, anti-oxidant, and anti-obesity properties, suggested by Dr. Cai X and colleagues(4).

Resveratrol, a phytochemical in the class of Stilbenoids, found abundantly in blueberry and grape also exhibited anti inflammatory effect against pro inflammatory cytokines(5). According to the investigated the effect of resveratrol on skin lesion, in an atopic dermatitis (AD) mouse model, showed that the phytochemical inhibited the prto inflammatory pathways against skin diseases through modulating the HMGB1 protein expression, a cytokine mediator of inflammation(6).

Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It has become very popular for commercial cultivation due to its health benefits. According to the University of Pretoria, the herb has been used in treatment of skin disorders, through ts moisturizing and anti-inflammatory effects in modulating the IgE levels of mouse model of atopic dermatitis (AD)(7).
Dr. Benson KF and colleagues in the Aloe vera-based extract of Nerium oleander leaves against skin diseases, said, "NAE-8(®), a novel component of a commercial cosmetic product, showed beneficial antioxidant protection in several cellular models, without the induction of leukocyte activation and secretion of inflammatory cytokines"(8).

Taking altogether, The combination of Green Tea, Aloe Vera juice and Grape may offer the potential effect not only in prevention of the onset and treatment of Pyoderma gangrenosum
 People who are at increased risk of Pyoderma gangrenosum are wise to drink at least one serving daily. People with  Pyoderma gangrenosum, should drink the juice as much as they can, depending to the toleration of digestive system.

Made From Fresh Fruits And Vegetable Recipes
Secret To A Vibrant And Healthy Lifestyle
That You Can Find Easily At The Comfort Of Your Kitchen.


References
(1) Innovations in natural ingredients and their use in skin care by Fowler JF Jr1, Woolery-Lloyd H, Waldorf H, Saini R.(PubMed)
(2) Anti-inflammatory ingredients by Wu J1.(PubMed)
(3) Epigallocatechin gallate and mitochondria-A story of life and death by Oliveira MR1, Nabavi SF2, Daglia M3, Rastrelli L4, Nabavi SM2.(PubMed)
(4) Pu-erh tea extract ameliorates high-fat diet-induced nonalcoholic steatohepatitis and insulin resistance by modulating hepatic IL-6/STAT3 signaling in mice by Cai X1,2,3, Fang C2,4, Hayashi S2,3, Hao S5, Zhao M6, Tsutsui H2,3, Nishiguchi S7, Sheng J8.(PubMed)
(5) One-year supplementation with a grape extract containing resveratrol modulates inflammatory-related microRNAs and cytokines expression in peripheral blood mononuclear cells of type 2 diabetes and hypertensive patients with coronary artery disease by Tomé-Carneiro J1, Larrosa M, Yáñez-Gascón MJ, Dávalos A, Gil-Zamorano J, Gonzálvez M, García-Almagro FJ, Ruiz Ros JA, Tomás-Barberán FA, Espín JC, García-Conesa MT.(PubMed)
(6) Resveratrol attenuates HMGB1 signaling and inflammation in house dust mite-induced atopic dermatitis in mice by Karuppagounder V, Arumugam S, Thandavarayan RA, Pitchaimani V, Sreedhar R, Afrin R, Harima M, Suzuki H, Nomoto M, Miyashita S,Suzuki K, Watanabe K.(PubMed)
(7) A comparison of the leaf gel extracts of Aloe ferox and Aloe vera in the topical treatment of atopic dermatitis in Balb/c mice by Finberg MJ1, Muntingh GL1, van Rensburg CE2.(PubMed)
(8) Antioxidant, anti-inflammatory, anti-apoptotic, and skin regenerative properties of an Aloe vera-based extract of Nerium oleander leaves (nae-8(®)) by Benson KF1, Newman RA2, Jensen GS1.(PubMed)

Sunday, May 22, 2016

The Smoothie of Brazil Nut, Tomato and Green Tea In reduced Risk and Treatment of Acquired immunodeficiency syndrome (AIDS) associated nephropathy

Kyle J. Norton(Scholar, master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Renal disease is associated to common complication in patients with human immunodeficiency virus (HIV) disease as a result of direct kidney infection with HIV or from the adverse effects of antiviral medication.

The smoothie for Reduced risk and Treatment of  Acquired immunodeficiency syndrome (AIDS) associated nephropathy
Yield: 2 serving (about 8 ounce each)
1 cup Tomato
1/2 cup Brazil nut
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minute. Set aside for cooling to room temperature)
1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The dream of finding the natural ingredient for prevention and treatment of Acquired immunodeficiency syndrome (AIDS), without adverse effects in replacement of conventional medication has not been abated. Some ingredients have to discard because of not achieving the same potent results in human trials.

Scientist community may have found the smoothie(combined ingredients of garlic, olive and coconut oils) with potential and therapeutic value for reduced risk and treatment of Acquired immunodeficiency syndrome (AIDS)without adverse effects.

Human immunodeficiency virus (HIV) is a lentivirus that causes acquired immunodeficiency syndrome (AIDS) of which can lead to the progression of weakened immune system casues of infectous diseases and cancers. According to the studies, patients with human immunodeficiency virus (HIV) are asscoiated to low levels of vitamin A and selenium(1).
Selenium, a chemical element with symbol Se and antioxidant found in Brazil nut, plays an important role in protection of cell against significant impairments of antioxidative defenses induced human immunodeficiency virus (HIV) (2).
Dr. Delmas-Beauvieux MC and colleagues at the Université Bordeaux II, suggested, selenium supplementation could be of great interest in protecting cells against oxidative stress and glutathione peroxidase (GPX), and glutathione (GSH) are important in expression of natural enzymatic defense system in detoxifying hydrogen peroxide(3).

Vitamin A, a bi-polar molecule formed by bonds between carbon and hydrogen, is a fat soluble vitamin converted from beta-carotene, a powerful antioxidant. Accoridng to the The University of Maryland School of Medicine, deficiency of vitamin A in human immunodeficiency virus (HIV) infection has been associated with more progressive HIV disease(4).
Dr.Mehta S and Dr. Fawzi W. in the study of the effects of vitamins, including vitamin A, on HIV/AIDS patients, said, "periodic vitamin A supplementation of HIV-infected infants and children is beneficial in reducing all-cause mortality and morbidity and is recommended"(5).

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate.
According to the Creighton University, green tea, epigallocatechin gallate, theaflavins may be effective in prevention and treatment of sexually transmitted infections caused by HIV (human immunodeficiency virus), HSV (herpes simplex virus) and HPV (human papilloma virus)(6).

Dr. Hamza A and Dr. Zhan CG. said, "(-)-epigallocatechin gallate (EGCG) from green tea is an inhibitor blocking gp120-CD4 binding" by blocking the initial step of HIV-1 entry into the cells"(7).
In support of above blocking, Dr. Williamson MP and colleagues at the University of Sheffield suggested, green tea Epigallocatechin gallate has a potential use as adjunctive therapy in HIV-1 infection(8) through its binding of HIV-1 glycoprotein (gp) 120 to the CD4 molecule on T cells.

The Smoothie of Brazil Nut, Tomato and Green Tea  may hold a key for further studies in production of a curable natural remedy for prevention and treatment of  Acquired immunodeficiency syndrome (AIDS) associated nephropathy.
.
People who are at  increased risk of Acquired immunodeficiency syndrome (AIDS) associated nephropathy due to family history, weaken immunity,....should drink at least one cup or more daily. People with Acquired immunodeficiency syndrome (AIDS) associated nephropathy may drink as much as they can, depending to the digestive toleration.

References
(1) The enzymatic antioxidant system in blood and glutathione status in human immunodeficiency virus (HIV)-infected patients: effects of supplementation with selenium or beta-carotene by Delmas-Beauvieux MC1, Peuchant E, Couchouron A, Constans J, Sergeant C, Simonoff M, Pellegrin JL, Leng B, Conri C, Clerc M.(PubMed)
(2) Effect of selenium supplementation on CD4+ T-cell recovery, viral suppression and morbidity of HIV-infected patients in Rwanda: a randomized controlled trial by Kamwesiga J1, Mutabazi V, Kayumba J, Tayari JC, Uwimbabazi JC, Batanage G, Uwera G, Baziruwiha M, Ntizimira C, Murebwayire A, Haguma JP,Nyiransabimana J, Nzabandora JB, Nzamwita P, Mukazayire E; Rwanda Selenium Authorship Group.(PubMed)
(3) Plasma Selenium Concentrations Are Sufficient and Associated with Protease Inhibitor Use in Treated HIV-Infected Adults by Hileman CO1, Dirajlal-Fargo S2, Lam SK3, Kumar J3, Lacher C4, Combs GF Jr4, McComsey GA5.(PubMed)
(4) Quantitation of parvalbumin+ neurons and human immunodeficiency virus type 1 (HIV-1) regulatory gene expression in the HIV-1 transgenic rat: effects of vitamin A deficiency and morphine by Sultana S1, Li H, Puche A, Jones O, Bryant JL, Royal W.(PubMed)
(5) Effects of vitamins, including vitamin A, on HIV/AIDS patients by Mehta S1, Fawzi W.(PubMed)
(6) Natural polyphenols: potential in the prevention of sexually transmitted viral infections by Date AA1, Destache CJ2.(PubMed)
(7) How can (-)-epigallocatechin gallate from green tea prevent HIV-1 infection? Mechanistic insights from computational modeling and the implication for rational design of anti-HIV-1 entry inhibitors by Hamza A1, Zhan CG.(PubMed)
(8) Epigallocatechin gallate, the main polyphenol in green tea, binds to the T-cell receptor, CD4: Potential for HIV-1 therapy. by Williamson MP1, McCormick TG, Nance CL, Shearer WT.(PubMed)

Saturday, May 21, 2016

The Delicious Smoothie of Curcumion, Aloe Vera juice and Grape for Prevention and Treatment of Rosacea

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of  Rosacea 
Yield: 2 servings (about 8 ounces each)
1 1/2 cups blueberry
1 tsp curcumin
1 cup green tea drink (Make from 4 grams of green tea and a cup of hot water lipped for 5 minutes. Set aside for cooling to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of Rosacea  has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Rosacea is a chronic inflammatory condition with redness or blushing facial skin. According to the University of Louisville, licorice, green tea, pomegranate, turmeric may be sued for treatment of Rosacea, due to its powerful anti inflammatory effect(1).
Dr. Wu J said, ".....active ingredients, anti-inflammatory properties, clinical effects, and therapeutic potential(rosacea, atopic dermatitis, sensitive and irritated skin, drug-induced skin eruptions, and psoriasis) of colloidal oatmeal, feverfew, licorice, aloe vera, chamomile, and turmeric"(2).

Recent studies by some renowned institutions suggested that Curcumin(5), Aloe Vera juice(7) and blueberry(4) may be the next generation of ingredient extracted from natural sources for reduced risk and treatment of Rosacea.

Resveratrol, a phytochemical in the class of Stilbenoids, found abundantly in blueberry and grape also exhibited anti inflammatory effect against pro inflammatory cytokines(3). According to the investigated the effect of resveratrol on skin lesion, in an atopic dermatitis (AD) mouse model, showed that the phytochemical inhibited the prto inflammatory pathways against skin diseases through modulating the HMGB1 protein expression, a cytokine mediator of inflammation(4).

Curcumin, is a major chemical constituent found in turmeric, which  is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia. According to the joint study lead by the Stony Brook University, the antioxidant inhibited two inflammatory diseases, periodontitis and rosacea, through inflammatory mediators expression(5).
In fact, Dr. Zhang Y and professors at the State University of New York at Stony Brook said, "Tetracyclines (TCs), (having uniquely modified curcumin as a "core" molecule), are known inhibitors of mammalian-derived MMPs, and non-antibiotic formulations of Doxycycline are FDA-approved to treat periodontitis and the chronic inflammatory skin disease, rosacea"(6).

Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It has become very popular for commercial cultivation due to its health benefits. According to the University of Pretoria, the herb has been used in treatment of skin disorders, through ts moisturizing and anti-inflammatory effects in modulating the IgE levels of mouse model of atopic dermatitis (AD)(7).
Dr. Benson KF and colleagues in the Aloe vera-based extract of Nerium oleander leaves against skin diseases, said, "NAE-8(®), a novel component of a commercial cosmetic product, showed beneficial antioxidant protection in several cellular models, without the induction of leukocyte activation and secretion of inflammatory cytokines"(8).

Taking altogether, The combination of Curcumin, Aloe Vera juice and Grape may offer the potential effect not only in prevention of the onset but also treatment of Rosacea.
 People who are at increased risk of Pyoderma gangrenosum are wise to drink at least one serving daily. People with  Rosacea, should drink the juice as much as they can, depending to the toleration of digestive system.

Made From Fresh Fruits And Vegetable Recipes
Secret To A Vibrant And Healthy Lifestyle
That You Can Find Easily At The Comfort Of Your Kitchen.

References
(1) Innovations in natural ingredients and their use in skin care by Fowler JF Jr1, Woolery-Lloyd H, Waldorf H, Saini R.(PubMed)
(2) Anti-inflammatory ingredients by Wu J1.(PubMed)
(3) One-year supplementation with a grape extract containing resveratrol modulates inflammatory-related microRNAs and cytokines expression in peripheral blood mononuclear cells of type 2 diabetes and hypertensive patients with coronary artery disease by Tomé-Carneiro J1, Larrosa M, Yáñez-Gascón MJ, Dávalos A, Gil-Zamorano J, Gonzálvez M, García-Almagro FJ, Ruiz Ros JA, Tomás-Barberán FA, Espín JC, García-Conesa MT.(PubMed)
(4) Resveratrol attenuates HMGB1 signaling and inflammation in house dust mite-induced atopic dermatitis in mice by Karuppagounder V, Arumugam S, Thandavarayan RA, Pitchaimani V, Sreedhar R, Afrin R, Harima M, Suzuki H, Nomoto M, Miyashita S,Suzuki K, Watanabe K.(PubMed)
(5) A novel chemically modified curcumin reduces severity of experimental periodontal disease in rats: initial observations by Elburki MS1, Rossa C2, Guimaraes MR2, Goodenough M1, Lee HM1, Curylofo FA2, Zhang Y3, Johnson F3, Golub LM1(PubMed)
(6) Design, synthesis and biological activity of new polyenolic inhibitors of matrix metalloproteinases: a focus on chemically-modified curcumins. by Zhang Y1, Gu Y, Lee HM, Hambardjieva E, Vranková K, Golub LM, Johnson F.(PubMed)
(7) A comparison of the leaf gel extracts of Aloe ferox and Aloe vera in the topical treatment of atopic dermatitis in Balb/c mice by Finberg MJ1, Muntingh GL1, van Rensburg CE2.(PubMed)