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Friday, April 22, 2022

Healthy Food Honey Normalizes the Levels of Blood Cholesterol with No Side Effects



Scientists may have found a natural alternative for the treatment of hyperlipidemia according to a study.
Hyperlipidemia is a condition of high levels of cholesterol in the bloodstream. Cholesterol is a waxy substance that is needed for the body to build cell walls, aid digestion, and make steroid hormones and vitamin D.

Cholesterol can be produced by the liver or by eating some fatty foods. There are 2 types of cholesterol, the low-density lipoprotein (LDL) which carries the aforementioned functions, and the high-density lipoprotein (HDL) which returns the cholesterol to the liver for reuse.

The healthy ratio of blood cholesterol is 4 (LDL)/1 (HDL). If you have a number that is lowers than 4, you have healthy blood cholesterol.

Hyperlipidemia is one member of the cluster conditions of metabolic syndrome, therefore, if you have a number that is higher than 4, your risk of cardiovascular is increased compared to people with healthy levels.

Although there are many risk factors associated with the onset of hyperlipidemia, some researchers suggested that the association between widespread obesity and hyperlipidemia in US adults is worrisome in the scientific community.

Dr. Boudewijn Klop and their colleagues at the Diabetes and Vascular Centre, Sint Franciscus Gasthuis wrote, "Obesity increases cardiovascular risk through risk factors such as increased fasting plasma triglycerides, high LDL cholesterol, low HDL cholesterol, elevated blood glucose, and insulin levels and high blood pressure. Novel lipid-dependent, metabolic risk factors associated with obesity are the presence of the small dense LDL phenotype, postprandial hyperlipidemia with an accumulation of atherogenic remnants, and hepatic overproduction of apoB containing lipoproteins".

And, "All these lipid abnormalities are typical features of the metabolic syndrome and may be associated with a pro-inflammatory gradient which in part may originate in the adipose tissue itself and directly affect the endothelium".


The results strongly suggested the association between obesity and the onset of abnormal blood cholesterol in the contribution to many complications and diseases.

Honey is a miraculous product made by bees using nectar from flowers.

The rich golden liquid is considered one healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.

Scientists on finding a natural compound for the treatment of cholesterol examined honey's effects on patients with high cholesterol concentrations.

The study included 60 volunteers with high cholesterol, stratified according to gender and hydroxymethyl-glutaryl-coenzyme A reductase inhibitor (statin) treatment (yes/no), randomized to receive 75 g of the honey solution or a honey-comparable sugar solution once daily over a period of 14 days.

Measurements repeated 2 weeks later, showed that BMI and high-density lipoprotein (HDL) cholesterol values were significantly correlated (r = -0.487; P < .001) as were BMI and a lower ratio of low-density lipoprotein (LDL) cholesterol to HDL cholesterol (r = 0.420; P < .001).

In other words, with injection of honey, subjects with a high BMI had a lower HDL cholesterol value.


Even though neither solution influenced significantly cholesterol or triglyceride values in the total group; substituting honey for sugar in their diet showed to reduce the BMI and lower the LDL cholesterol value.


The finding suggested honey does not have a direct effect on normalizing the levels of blood cholesterol but indirectly reduces the patient's BMI value, which has been found to have strong effects in decreasing the levels of cholesterol.

Furthermore, according to research presented at the national meeting of the American Chemical Society, the world's largest scientific society, honey fights cholesterol as well as some fruits and vegetables.

The study included 25 men between the ages of 18 - and 68 who are given a mixture of water and honey, about four tablespoons per 16-ounce glass in a five-week.


A blood sample withdrawn at the end of the experience showed reduced levels of cholesterol by improving the antioxidant levels in the blood.



Moreover, the application of the mixture also has a significant effect in reducing the risk of atherosclerosis caused by plaque such as cholesterol and other substances build up on the arterial wall.


The onset of atherosclerosis is a major cause of heart disease in the US.

The results suggested that replacing the use of sweetening agents, like sugar with honey may improve the antioxidant status in reducing the risk of cholesterol overexpression in the bloodstream.



Taken altogether, honey may be considered a functional remedy for the prevention and treatment of high blood cholesterol, pending the confirmation of a large sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.

Sources
(1) Effect of honey on serum cholesterol and lipid values by Münstedt K1, Hoffmann S, Hauenschild A, Bülte M, von Georgi R, Hackethal A. (PubMed)
(2) Honey Fights Cholesterol As Well As Some Fruits And Vegetables by American Chemical Society. (Science Daily)
(3) Dyslipidemia in Obesity: Mechanisms and Potential Targets by Boudewijn Klop, Jan Willem F. Elte, and Manuel Castro Cabezas. (PMC)

Friday, April 15, 2022

Broccoli and Tomato Inhibits the Elevated Hormone Resistin Associated with Insulin Resistance


Insulin resistance is a hallmark of type 2 diabetes characterized by the inability of the body to use the insulin produced by the pancreas properly.

In other words, signals sent out by the hormone insulin caused by the clog-up of the insulin receptors was ignored by the cell of the muscles, body fat, and liver that process the function to convert glucose into energy.



More precisely, as the clogged-up insulin receptors ignore the signals of the hormone insulin, insulin resistance develops, leading to more production of insulin by the beta cells and over time causing permanent damage to the cells in the pancreas.


Epidemiologically, people with insulin resistance are associated with an increased risk of prediabetes, type 2 diabetes, and chronic conditions such as heart attacks, strokes, and cancer.


A 2016 joint study led by the MSA University, suggested that tomato and broccoli extract affects on glucose homeostasis in high fat diet-induced obesity in rats by regulating the adipocyte hormone Resistin.


Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae. The vegetable has large flower heads, usually green in color and the mass of flower heads is surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.


Tomato is red, edible fruit, genus Solanum, belongs to the family Solanaceae, native to South America. Because of its health benefits, tomato is grown worldwide for commercial purposes
and often in the greenhouse.

According to the US statistics, approximately, 60 to 70 million individuals are affected by insulin resistance with 40% of individuals older than 50 years may be at risk of insulin resistance.

Believe it or not, the most common risk factors associated with insulin resistance are obesity and hypertension associated with the promotion of a high-fat diet over the past few decades.

Dr. Merat S, the lead scientist wrote, " Contrary to expectation, IR was induced in mice fed the Western diet,,,. The Western diet group had higher average glucose levels (187+/-16 versus 159+/-12 mg/dL) and 4.5-fold higher plasma insulin levels".


A total of 48 male albino rats included in the study were divided into 8 groups as follows: control, HFD, stop fat diet (SD), Tomato 200 mg/kg (T200), Tomato 400 mg/kg (T400), Broccoli 200 mg/kg (B200), Broccoli 400 mg/kg (B400), and Chromax (CX).

According to the tested differentiation after 1 month of treatment,

* Serum levels of resistin were significantly reduced in all groups treated with tomato, broccoli, and CXIn other words, T 200, T 400, B 200, B 400 and CX groups reduced levels of resistin to: 4.13 ± 0.22 ng/ml, 1.51 ± 0.04 ng/ml, 4.13 ± 0.22 ng/ml, 2.32 ± 0.15 ng/ml and 1.37 ± 0.03 ng/ml, compared to the baseline, respectively.

Where resistin is an adipocyte hormone associated with regulating glucose metabolism. Elevated levels of resistin have been found to cause insulin resistance in diabetics.


Increased levels of serum levels of leptin significantly reduced anti-elevated levels of resistin in the T 400 group compared to the B 400 and CX groups.

Additionally, serum levels of adiponectin associated with insulin resistance were significantly increased in the T 400 group (131 ± 3.84 pg/ml).


The results strongly suggested that broccoli and tomato extract inhibited the elevated levels of hormone resistin that cause insulin resistance in the high-fat-diet-induced diabetes animal model.


Based on the finding, researchers said, " tomato and broccoli extract treatment regulates glucose homeostasis via reduction of serum resistin and may be a useful non-pharmacological therapy for obesity".

Taken altogether, broccoli and tomato extract may be considered supplements for the prevention and treatment of insulin resistance, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional's Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca



Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Resistin mediates tomato and broccoli extract effects on glucose homeostasis in high fat diet-induced obesity in rats by Aborehab NM1, El Bishbishy MH2, Waly NE. (PubMed)
(2) Western-type diets induce insulin resistance and hyperinsulinemia in LDL receptor-deficient mice but do not increase aortic atherosclerosis compared with normoinsulinemic mice in which similar plasma cholesterol levels are achieved by a fructose-rich diet by Merat S1, Casanada F, Sutphin M, Palinski W, Reaven PD. (PubMed)

Saturday, April 9, 2022

Honey in the Prevention and Treatment of Diarrhea



Scientists may have found a natural alternative for the treatment of diarrhea, according to studies.
Diarrhea is a condition of loose, watery stools. Acute diarrhea is a common problem in North America that lasts for a very short time.

However, chronic diarrhea can be worrisome. The most common causes of chronic diarrhea are diseases associated with the gastrointestinal tract, including irritable bowel syndrome (IBS), inflammatory bowel disease (Crohn's disease and ulcerative colitis), and malabsorption syndromes.

According to the statistics, acute diarrhea is one of the common causes of death among children younger than 5 years old worldwide.


The disease is associated mostly in the countries which poor environmental sanitation, inadequate water supplies, and poverty.


There are many risk factors involved in the onset of the syndrome, including demography, socio-economy, poor water supply, poor sanitation, poor hygiene practices, breastfeeding, and malnutrition.


Some researchers suggested that a severely weakened immune system such as the use of immune-suppressive medicine and the elderly may also at a higher risk of diarrhea.


Dr. Bouchaud O in examing the risk of immune deficiency and diarrhea wrote, "With a prevalence of approximatively 50%, diarrhea is a frequent event in an immune deficiency of any cause".

And "Gram-negative infections and Clostridium difficile colitis have to be diagnosed because efficient treatment is available. In these patients usually in bad general condition, because diarrhea is often of unknown etiology or noncurable, the diagnostic and therapeutic strategy has to be pragmatic in order to control the symptoms without an excess of invasive procedures".

These results clearly suggested that if you have a severely weakened immune system, you are at higher risk of bacterial infected diarrhea.

Honey is a miraculous product made by bees using nectar from flowers.

The rich golden liquid is considered one healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.

Researchers searching for a natural compound for the treatment of diarrhea evaluated the honey gastroprotective effect against diarrhea.

Injection of honey induced a significant reduction in the duration of bacterial diarrhea, and it had worked well as a substitute for glucose in an oral rehydration solution containing electrolytes.

In nonbacterial gastroenteritis, honey exerted a similar effect as glucose on the duration of diarrhea.

In an array of gram-positive and gram-negative bacteria, most pathogenic bacteria failed to grow in honey at a concentration of 40% and above, similar to those studies of honey on Staphylococcus aureus, Proteus mirabilis, and Candida albicans failed to grow in the presence of undiluted honey in vitro experiments.

Honey-agar all intestinal bacterial pathogens failed to grow at a concentration of 40% and above of pure honey, compared to those of bacterias in control plates and different growth media.


Scientists wrote in the final report, "Findings from studies on honey have thus shown that when given with an ORS it shortens the duration of bacterial diarrhea and may safely be used as a substitute for glucose, provided that the solution contains electrolytes".


In order to reveal more information about honey anti-diarrhea activity, researchers examined the honey on diarrhea and fecal microbiota in critically ill patients.

The double-blind, randomized controlled single-center study, included 32 patients randomly selected to receive a high protein kitchen enteral diet or honey as 10% of their carbohydrate intake.


The treatment group showed an insignificant increase in the frequency of bifidobacterium DNA by study day 7 in comparison with the control group and a considerable reduction in diarrhea.

Honey group also reduced the length of the Intensive Care Unit and the development of organ failure in critically ill patients.

Taken altogether, honey may be considered a functional remedy for the prevention and treatment of diarrhea, pending the confirmation of a large sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional's Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.

Sources
(1) Honey: its antibacterial action in the treatment of gastroenteritis.[No authors listed]. (PubMed)
(2) Effect of Honey on Diarrhea and Fecal Microbiotain in Critically Ill Tube-Fed Patients: A Single Center Randomized Controlled Study by Zahra Vahdat Shariatpanahi,1 Fatemeh Jamshidi,1 Javad Nasrollahzadeh,1 Zohreh Amiri,1 andHouman Teymourian. (PubMed)
(3) [Diarrhea in immune deficiency status].[Article in French] by Bouchaud O. (PubMed)

Sunday, April 3, 2022

Healthy Food Tomatoes Protect the Ovaries Against the Alternation of Cell DNA

Ovarian cancer is a medical condition caused by irregular cell growth in the lining tissues of the ovary.

Most cases of ovarian cancer begin in the cells on the surface of the inner lining of the ovary tissue before penetrating into deeper layers and colonizing the entire organ to induce secondary metastasis through blood and fluids circulation.

Ovarian cancer can be divided into the types below
* Epithelial Ovarian Cancer
The epithelial ovarian tumor also is known as a surface epithelial-stromal tumor, caused by the alternation of DNA of the cell on the surface of the ovary. Epithelial ovarian tumor is the most common form of ovarian cancer accounting for over 90% of all cases, including serious tumor, endometrioid tumor, and mucinous cystadenocarcinoma.

* Germ cell ovarian cancer
Germ cell ovarian tumor is a cancer of the egg-producing cells within the ovary and can be cancerous or non-cancerous tumors. The condition tends to occur in children and teens as a result of birth defects.

* Sex cord-stromal ovarian cancer
Sex cord-stromal ovarian tumor is a cancer of the tissue of the ovary that accounted for 8% of ovarian cancers. It is believed that the cancer is caused by excess estrogen produced by sex cord-stromal ovarian tumors. Sex cord-stromal ovarian cancer tends to develop in the older age group.

The most common symptoms of ovarian cancer are abdominal pain, bloating or swelling, quickly feeling full when eating, discomfort in the pelvis area, and change of bowel movement accompanied by the general symptoms shared by other cancers, such as unintended weight loss, gastrointestinal discomfort, loss of appetite and persistent fatigue.


Some researchers suggested that the widespread obesity caused by the promotion of a high-fat diet in the Western world may correlate to the increased risk of ovarian cancer.

Dr. Foong KW, wrote, " " 14 studies found a statistically significant positive association between ovarian cancer risk and higher body mass index, 26 studies found no significant association, and 3 studies found a negative association between ovarian cancer risk and higher body mass index".


Tomato is red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.

With an aim to find a potential compound for the treatment of ovarian cancer, researchers investigated the combined effect of reduced graphene oxide-silver nanoparticles (rGO-AgNPs, with biomolecule called lycopene,) and trichostatin A (TSA) in human ovarian cancer cells (SKOV3).

According to the tested assays, AgNPs uniformly distributed on the surface of graphene sheet with an average size between 10 and 50 nm, rGO-Ag and TSA demonstrated significant inhibition of the cell viability in a dose-dependent manner.

At low concentration, the combination of rGO-Ag and TSA not only have a significant effect on cell viability, and increased cytotoxicity but also inhibited the level of malondialdehyde (oxidative stress) and decreased the level of glutathione (antioxidants) that induced cancer cell mitochondrial dysfunction.

Based on the findings, researchers suggested, " This combination chemotherapy could be possibly used in advanced cancers that are not suitable for radiation therapy or surgical treatment and facilitate overcoming tumor resistance and disease progression".

Furthermore, the combination of rGO-Ag and TSA-induced cancer cell apoptosis was attributed to their pronounced effect on DNA fragmentation and double-strand breaks.

In order to reveal more information about lycopene, and anti-ovarian cancers activity scientists examined the protective role of dietary lycopene against the risk of ovarian cancer.



The search of the meta-analysis. identified 10 studies selected from the PubMed database, and final risk estimates, using a random-effects model showed that lycopene showed an effect on the risk of ovarian cancer among postmenopausal women, compared to an insignificant reverse association between dietary lycopene and ovarian cancer risk to other groups.

In other words, rGO-AgNPs, with a biomolecule called lycopene, are effective in reducing the risk and treatment of ovarian cancer in all groups compared to that dietary lycopene in postmenopausal women.


Taken altogether, tomatoes processed with abundantly bioactive compound lycopene may be considered supplements for the prevention and treatment of ovarian cancer, pending the confirmation of the larger sample size and multicenter human study.


Intake of lycopene in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Novel biomolecule lycopene-reduced graphene oxide-silver nanoparticle enhances apoptotic potential of trichostatin A in human ovarian cancer cells (SKOV3) b yZhang XF1,2, Huang FH1, Zhang GL3, Bai DP4, Massimo DF5, Huang YF4, Gurunathan S. (PubMed)
(2) Meta-analysis of the association between dietary lycopene intake and ovariancancer risk in postmenopausal women by Li X1, Xu J. (PubMed)
(3) Obesity and ovarian cancer risk: A systematic review by Foong KW1, Bolton H. (PubMed)