Get Pregnant Naturally

Get Pregnant Naturally
".....Utilizing Traditional Chinese Medicine in Tonifying Energy flow to the Reproductive System Channels In Men and Women for Natural Conception, including Couple Who were diagnosed with Unexplained causes of Infertility...." Chantel M.

Wednesday, April 8, 2020

Ginger, the Natural Antibiotics Alternative Functional Spice

Ginger may be considered a natural antibiotics alternative for the treatment of Candida albicans overgrowth without inducing any side effects, some scientists suggested.

Candida albicans is an opportunistic pathogenic yeast formed part of the commensal gastrointestinal mycobiota.

Candida albicans overgrowth is the most prevalent cause of fungal infections in humans.

Epidemiological studies strongly suggested that long-term users of antibiotics that cause an imbalance of the gut microbiome, weakened the immune system, unhealthy diet, and women who are pregnant and hormone imbalance of hormone near menstruation are susceptible to the onset of the condition.

If you experience symptoms of oral thrush, recurring genital or urinary tract infections, persistently digestive issues, joint pain. particularly, in the skin and nail fungal infections, you may have a yeast infection.

Please check with your doctor to rule the Candida albicans overgrowth possibility.

Dr. Carol A. Kumamoto in the research team of infectious diseases in the study "Inflammation and gastrointestinal Candida colonization" suggested that a Candida albicans overgrowth can be caused by other medical conditions, associated to a digestive disorder.

In the study, the doctor wrote, "Recent studies, however, show that high-level Candida colonization is associated with several diseases of the gastrointestinal tract. Further, results from animal models argue that Candida colonization delays healing of inflammatory lesions and that inflammation promotes colonization".

And, "Both inflammatory bowel disease and gastrointestinal Candida colonization are associated with elevated levels of the pro-inflammatory cytokine IL-17. Therefore, effects on IL-17 levels may underlie the ability of Candida colonization to enhance inflammation".


These results strongly suggested, inflammation flames the overgrowth of Candida colonization in return, the overgrowth of Candida albicans induces persistently low-grade inflammation.

Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.

The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.

With an aim to find the natural ingredient or whole food for the replacement of the conventional antibiotics without inducing any effects, researchers at the Teikyo University Institute of Medical Mycology, investigated the effect of ginger against infection caused by Candida albicans.

4 preparations of the essential oils of young and mature rhizomes, air-dried and steamed rhizomes, and seed rhizomes of Zingiber officinale Roscoe (ginger) were compared in the study.
* All ginger essential oils processed a significant anti-Candida albicans activity.

* Essential oil from the seed and air-dried rhizomes, exerted the highest effect compared to other preparations.

* The seed and air-dried rhizomes essential oils also had a potent inhibitory activity compared to ginger oleoresins obtained by ethanol and hypercritical carbon dioxide extraction and essential oils of 5 other plants in the family Zingiberaceae.
According to the chemical constituents assay, [6]-shogaol was most active against filament formation and growth of C. Albicans, followed by citral and [6]-gingerol.


Furthermore, ginger oleoresin, especially that obtained by ethanol extraction, with a high [6]-gingerol content exhibited potent anti the growth of C. Albicans compared to essential oils of ginger and other Zingiberaceae plants.

Moreover, in a vitro joint study by the Institute of Science and Technology, researchers launched an investigation to evaluate the antimicrobial activity of 2% chlorhexidine gel (CHX) isolated from the ginger as auxiliary chemical substance and intracanal medications on Candida albicans.


The study included 48 single-rooted human teeth randomly divided into fourr groups (n = 12), according to intracanal medications used: (1) Calcium hydroxide + apyrogenic saline solution (Ca(OH)2 + SS), (2) 20% ginger glycolic extract (GEN), (3) calcium hydroxide + 20% ginger glycolic extract (Ca(OH)2 + GEN), (4) apyrogenic SS (control).


At the end of the experiment, researchers found that
* CHX was effective in the complete elimination of E. coli and C. albicans.

* ChX also significantly reduced and then completely eliminated E. faecalis after intracanal medication.

* All other applications also revealed a reduction of endotoxins, the outer membrane of the cell wall of Gram-negative bacteria.

In the final report, the research team concluded, "CHX and intracanal medication used were able to eliminate the microorganisms from the root canal; the endotoxins were reduced, yet not completely eliminated".

These results strongly suggested that ginger bioactive compound processes a significant antibacterial activity, particularly in those of C. albicans.


Taken all together, there is no doubt that ginger may be considered a functional food for the prevention and combined with primary medicine for the treatment of yeast infection with no side effects.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.



Sources
(1) Anti-Candida and radical scavenging activities of essential oils and oleoresins of Zingiber officinale Roscoe and essential oils of other plants belonging to the family Zingiberaceae by Takahashi M1, Inouye S, Abe S.(PubMed)
(2) Action of Chlorhexidine, Zingiber officinale, and Calcium Hydroxide on Candidaalbicans, Enterococcus faecalis, Escherichia coli, and Endotoxin in the Root Canals by Valera MC1, Oliveira SA2, Maekawa LE2, Cardoso FG3, Chung A2, Silva SF2, Carvalho CA2. (PubMed)
(3) Inflammation and gastrointestinal Candida colonization by Carol A. Kumamoto. (PMC)

Tuesday, April 7, 2020

Healthy Cruciferous Vegetables Inhibit the Risk of Gastric/Stomach Cancer

Gastric cancer is a medical condition characterized by irregular and uncontrollable cell growth in the stomach.

Most cases of gastric cancer start in the cells on the surface of the inner lining of stomach tissue.
Due to the small size at the early stage, gastric cancer is asymptomatic.

However, at the later stage, after penetrating into the deeper layers of the stomach, the cancer cell may travel a distance away to infect other healthy tissues and organs, leading to secondary metastasis.

Researchers do not know why some people with the same health condition are susceptible to the risk of gastric cancer, while others do not. The exact causes of gastric cancer are also unknown. However, some researchers suggested that Age, diet, and stomach disease, such as can increase the risk of developing gastric cancer.

The most common symptoms of gastric cancer are stomach pain, nausea and vomiting, loss of appetite,... and indigestion. However, common symptoms of unexpected weight loss and stomach ulcers can only be found in gastric cancer while iron-deficiency anemia.

According to the statistics provided by the American Cancer Society, in 2019, approximately, 27,510 cases of stomach cancer will be diagnosed (17,230 in men and 10,280 in women) and 11,140 people will die from gastric cancer (6,800 men and 4,340 women).

Overall, the 5-year survival rate for people with gastric cancer is 31%. Cancer diagnosed at the localized stage have a 5 years survival rate of 67%.

Out of many risk factors associated with the onset of cancer, aging may be one of the major risk factors that cause the disease onset as cancer has been found to have a peak incidence between 50 and 70 years of age.

On finding a potential plant that processes anti-invasive cancer activity researchers examined the relationship between consumption of cruciferous vegetables (CV) in the risk of gastric cancer.


According to the meta-analysis that summarize available evidence from epidemiological studies published reports of CV intake and gastric cancer were identified using MEDLINE (PubMed), EMBASE, and Web of Science databases through to the end of September 2012, including 16 case-control and 6 prospective studies,

* The pooled studies showed a significantly inverse association between CV (relative risk = 0.81; 95% confidence interval, 0.75-0.88) intake and gastric cancer risk, with little heterogeneity (Q = 27.27, P = 0.292, I(2) = 12.0%).

* In a separate analysis, the case-control studies of CV intake yielded significant results compared to the borderline statistical significance of CV intake yielded in the prospective studies.

* Moreover, significant results were consistent for high-quality studies, for North American, European, and Asian studies, for studies on males, and for studies on non-cardia gastric cancer.

Based on the findings, researchers said, "... this meta-analysis provides evidence that high intake of CV was inversely associated with the risk of gastric cancer and non-cardia gastric cancer in humans.

Taken altogether, CV with rich phytochemicals may be considered a functional food for the prevention and treatment of gastric cancer, pending to the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Cruciferous vegetable consumption and gastric cancer risk: a meta-analysis of epidemiological studies by Wu QJ1, Yang Y, Wang J, Han LH, Xiang YB. (PubMed)

Monday, April 6, 2020

Healthy Food Onion Protects the Cell DNA Against the Risk of Ovarian Cancer

Cancer is a class of diseases caused by irregular cell growth due to the alternation of the DNA.

After penetrating into deeper layer tissues of a specific organ, the proliferative tumor cell can travel a distance away from the originated site to invade other healthy tissues, via lymph or blood.

The most advanced stage of cancer may result in the death of the patients.


The ovaries are an -shaped ovum-producing reproductive organ in part of a woman's reproductive system connected to the fallopian tubes and attached to the outer layer of the uterus via the ovarian ligament. Usually, the left and right ovary take a turn to release an egg every month.

Ovarian cancer is a condition of abnormal cell growth of ovarian cells that start in the cells on the surface of the inner lining tissue of the ovary have become cancerous. Ovarian cancer is one of the most common cancer in the US, according to the statistics adapted from the American Cancer Society's publication,.

Cancer Facts & Figures 2010, an estimated 21,880 women in the United States will be diagnosed with ovarian cancer and 13,850 deaths.

The exact causes of ovarian cancer are unknown. However, the most common prevalent factors associated with increased risk of ovarian cancer are

*Age
The risk of ovarian cancer increases for women between 50 to 70 years of age.


* Genetic preposition
Women who carry certain mutation genes such as BRCA1 and BRCA2 account for 5%–13% of ovarian cancers.

* Family history
The risk of the disease increases, if one of your direct member family has a history of cancer.

* Never pregnant
Researchers found that the risk of ovarian cancer is lower with numbers of pregnancy.

* Race
White women are associated with a higher risk than other races.

* Hormone therapy
Risk of ovarian cancer increase with the use of hormone replacement therapy in post-menopausal women.

* Chemicalsexposures
Certain chemicals such as asbestos also increase the risk of ovarian cancer.

* High fat dietary
Researchers found that women who diet high in saturated fat and trans fat are at higher risk.

* Fertility medication
Drugs used to enhance fertility such as Clomiphene citrate may increase the risk of ovarian cancer.

* Milk
According to the BBC, researchers found that women who drank two or more glasses a day were at double the risk of those who did not consume it at all, or only in small amounts.

The onion is a plant in the genus Allium, belonging to the family Alliaceae, a close relation of garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.


Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.

On finding a potential compound for the treatment of lung cancer, researchers examined the effects of onionin A (ONA) derived from the onion in the inhibition of tumor-associated macrophages (TAMs) in the M2 phenotype.


According to the tested analysis.* Onionin A (ONA )inhibits ovarian cancer cell proliferation induced by co-culture with human macrophages.

* Onionin A directly suppressed lung cancer cell proliferation.

* Onionin A enhanced the effects of anti-cancer drugs was also observed.

* In ovarian cancer cells. signal transducer and activator of transcription 3 (STAT3) involved in cell proliferation and chemo-resistance were significantly suppressed by ONA.

* Additionally, ONA inhibited cancer progression and prolonged the survival time in a murine ovarian cancer model under single and combined with chemo drug treatment conditions.

Based on the finding, researchers said, "ONA is considered useful for the additional treatment of patients with lung cancer owing to its suppression of the pro-tumor activation of tumor-associated macrophages (TAMs) and direct cytotoxicity against cancer cells".

Taken altogether, onion processed a higher mount of onionin A (ONA) may be considered a remedy for the prevention and treatment of lung cancer, pending to the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Onionin A inhibits ovarian cancer progression by suppressing cancer cell proliferation and the protumour function of macrophages by Tsuboki J1,2, Fujiwara Y1, Horlad H1, Shiraishi D1, Nohara T3, Tayama S2, Motohara T2, Saito Y1, Ikeda T3, Takaishi K2, Tashiro H4, Yonemoto Y5, Katabuchi H2, Takeya M1, Komohara Y. (PubMed)
(2) Lung Cancer by Kyle J. Norton

Sunday, April 5, 2020

Banana, The Potential Gastric Ulcer Healing Functional Food

Banana may have a potential effect in protecting the gastrointestinal tract against the formation of gastric ulcers, some scientists suggested.

Gastric ulcers are open sores that develop on the inside lining of your stomach.

The most common cause of gastric ulcers is associated with the infection of the bacterium Helicobacter pylori (H. pylori). However, patients who are the long-term users of aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) also at a higher risk of gastric ulcers.


The long-term untreated gastric ulcers can result in gastric adenocarcinoma development.

Although there are some disagreements that a poor diet can cause gastric ulcers, some researchers suggested that a diet rich, fatty or spicy foods such as the Western diet and unhealthy lifestyle such as high caffeine. and excessive alcohol consumption also elevates the onset of the disease.


Therefore by following a healthy diet with more fruits and vegetables, whole grainless red meat and processed foods accompanied by a healthy choice of lifestyle and moderate exercise, one can lower the risk gastric ulcer substantially.


Dr. the lead author in the study, "Nutritional care in peptic ulcer" wrote, "Dietotherapy, as well as caloric distribution, should be adjusted to the patient's needs aiming to normalize the nutritional status and promote healing. Recommended nutrients can be different in the acute phase and in the recovery phase, and there is a greater need for protein and some micronutrients, such as vitamin A, zinc, selenium, and vitamin C in the recovery phase. In addition, some studies have shown that vitamin C has a beneficial effect on the eradication of H. pylori. Fibers and probiotics also play an important role in the treatment of peptic ulcer, because they reduce the side effects of antibiotics and help reduce treatment time.".

These results suggested that gastric ulcers not only can be prevented by the change of diet but can also be treated by modifying the antioxidant and nutrients intake.

Banana is the common name of a genus of tropical herbaceous plants. It can grow from 3 to 9 m and belongs to the family of the lily and the orchid.

The Banaras Hindu University in the reaffirming the expression of the inflammatory cytokines occurred in the onset of gastric ulcer onset launched an investigation to examine the effect of a Musa sapientum fruit (banana extract, MSE) extract the acetic acid (AA)-induced gastric ulcer (GU) in diabetic (DR) rat


A selected rat model was given MSE (100 mg/kg, oral), omeprazole (OMZ, 2.0 mg/kg, oral), insulin (INS, 4 U/kg, sc) or pentoxyphylline (PTX, 10 mg/kg, oral) once daily for 10 days in 14 days post-streptozotocin (60 mg/kg, intraperitoneal)-induced diabetic rats before the normal/diabetic rats were received CMC for the same period after induction of GU with AA.


According to the ulcer index, TNF-α and IL-1β were observed in normal (NR)-AA rat given the acetic acid (AA) compared to the NR-normal rats group.. the expression of proinflammatory presentation suggested that acetic acid (AA) has caused gastric damage.

Application of Musa sapientum fruit (MSE) extract inhibited the gastric ulcer expression through significant normalizing the levels of the blood glucose and gastric mucosal cytokines, TNF-α and IL-1β and growth factor, TGF-α, compared to OMZ (antiulcer drug).


Further analysis suggested that the efficacy of Musa sapientum fruit (MSE) extract was attributed to the presence of phytochemicals saponins, flavonoids, glycosides, steroids, and alkaloids.

Dr. Kumar M, the lead scientists said, "MSE showed antidiabetic and better ulcer healing effects compared with OMZ (anti-ulcer drug)".


Additionally, in the study of the antiulcer and mucosal defensive factors effects of methanolic extract of Musa sapientum var. Paradisiaca (MSE, 100 mg/kg) in normal and non-insulin dependent diabetes mellitus (NIDDM) rats. NIDDM was induced by administering streptozotocin (STZ, 70 mg/kg, ip) to 5 days old rat pups also found that

* The effects of MSE were effective compared with the known ulcer protective drug, sucralfate (SFT, 500 mg/kg) and anti-diabetic drug glibenclamide (GLC, 0.6 mg/kg) when administered orally, once daily for 6 days against gastric ulcers (GU).

* The MSE extracts to reverse the changes in gastric mucosal glycoproteins, cell proliferation, free radicals (lipid peroxidation and nitric oxide) and anti-oxidants enzymes (superoxide dismutase and catalase) and glutathione (GSH) levels induced by administering streptozotocin.

* MSE showed better ulcer protective effect in NIDDM rats compared with SFT and GLC in CRS-induced GU

* The extracts restore the levels of the gastric mucosal glycoprotein which was reduced in the NIDDM rats without having any effect on cell proliferation.

* MSE pretreatment showed a reversal in the levels of all the parameters better than GLC.caused by the injection of streptozotocin.

Final differentiation discovered that the efficacy of MSE in the inhibition of gastric ulcers was attributed to the predominant effect on the mucosal glycoprotein, cell proliferation, free radicals, and antioxidant systems.

Taken all together, banana processed abundantly phytochemicals may be considered a functional food for the prevention and an adjunct therapy combined with the primary medicine for the treatment of gastric ulcer without inducing any side effects.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Healing effects of Musa sapientum var. paradisiaca in diabetic rats with co-occurring gastric ulcer: cytokines and growth factor by PCR amplification by Kumar M, Gautam MK, Singh A, Goel RK1.(PubMed)
(2) Effect of plantain banana on gastric ulceration in NIDDM rats: the role of gastric mucosal glycoproteins, cell proliferation, antioxidants and free radicals by Mohan Kumar M1, Joshi MC, Prabha T, Dorababu M, Goel RK. (PubMed)
(3) Indigenous anti-ulcer activity of Musa sapientum on peptic ulcer. by Prabha P1, Karpagam T, Varalakshmi B, Packiavathy AS.(PubMed)

Saturday, April 4, 2020

The Effects of Strawberries on Heart Diseases

Strawberry is a genius of Fragaria × ananassa belongs to the family Rosaceae. They have been grown all over the world with a suitable climate for commercial profits and for health benefits.

Besides cancer, heart disease kills more than 2,000 Americans every day. Approximately 60 million Americans have heart disease. There are many causes of heart diseases. Most heart diseases are caused by high blood pressure contributes to the hardening of the arteries. High levels of bad cholesterol (LDL) build up in the arteries as a result of an uncontrolled diet with high levels of saturated fat and trans fat. All these add to the formation of atherosclerosis lesions and eventually arterial blockage or anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart.


Nutrients and Chemicals constituents
1. Carbohydrate
2. Dietary fiber
3. Omega 3 fatty acid
4. Calcium
5. Iron
6. Magnesium
7. Phosphorus
8. Potassium
9. Sodium
10. Zinc
11. Copper
12. Manganese
13. Selenium
14. Vitamin C
15. Thiamin
16. Niacin
17. Pantothenic acid
18. Vitamin B-6
19. Folate
20. Vitamin B-12
21. Vitamin A
22. Vitamin E
23. Vitamin K
24. Etc.


The major chemical compounds include anthocyanin and ellagitannins and p-Hydroxybenzoic acid, p-coumaric acid, ellagic acid, cyanidin-3-glucoside, pelargonidin-3-glucoside, kaempferol, quercetin, and myricetin

The benefits
Anthocyanin-rich foods, blueberries, and strawberries intake is found to be potential in preventing myocardial infarction (MI) in young and middle-aged women, according to study, as it associated with a decreased risk of MI in a comparison of those consuming >3 servings a week and those with lower intake. In other studies, the water-soluble pigments, Anthocyanins display wide range of biological activities including antioxidant, anti-inflammatory, antimicrobial and anti-carcinogenic activities and a variety of effects on blood vessels, platelets and the risk of coronary heart diseases. In fact, Dietary intakes of flavanones, anthocyanidins, and certain foods rich in flavonoids were associated with reduced risk of death due to CHD, CVD, and all causes.


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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The Side effects
1. Some people may beexperience anaphylactoid reaction to the consumption of strawberries


2. Oxalation

Oxalates in high concentration can cause problem for people with kidney diseases.

3. Etc.



References





(1) High anthocyanin intake is associated with a reduced risk of myocardial infarction in young and middle-aged women by Cassidy A, Mukamal KJ, Liu L, Franz M, Eliassen AH, Rimm EB..(PubMed)





(2) Anthocyanins and heart health by Mazza GJ.(PubMed)





(3) Flavonoid intake and cardiovascular disease mortality: a prospective study in postmenopausal women. byMink PJ, Scrafford CG, Barraj LM, Harnack L, Hong CP, Nettleton JA, Jacobs DR Jr.(PubMed)

Friday, April 3, 2020

Healthy Foods Apricot and Plum, the next Generation of Oral Hygiene

People with the problem with oral hygiene may consider adding Apricot and Plum into their diet, a new study suggested. In fact, the foods not contain a measurable amount of nutrients which are important to maintain the proper growth and body functions, but also enhance the immune system in fighting against the invasion of foreign substances, including bacterial and viral agents.

Patients with oral hygiene incompetence may be experiencing certain dental consequences such as gum diseases including cavities or even tooth loss.

According to the study by the University of Karachi, butanoic extract from Prunus armeniaca exhibited antibacterial activity against both Gram-positive and Gram-negative bacteria(1).

Mei, another member of the Prunus armeniaca, a favorite snack of Asian women, especially for those in the early stage of pregnancy, probably due to its sour taste, is also found to improve oral hygiene. According to the study of the University of Hong Kong, in the differentiation of the antibacterial effectiveness of 20 traditional Chinese herbs. Mei was found to exert a significant effect against all testing oral bacteria, namely, Streptococcus mitis, Streptococcus sanguis, Streptococcus mutans and Porphyromonas gingivalis(3).

Organic acids, the main ingredient of Fructus mume extract, also showed strong evidence in enhancing oral hygiene through its antimicrobial effect on the orthodontic bracket in vitro by increasing the number of dead bacteria on the surface(4).

Mei or Lu E Mei is also known as Plum. The sour and warm herb has been used in TCM to treat diarrhea, pain from colic caused by ascaris, alleviates thirst, as well as other digestive system diseases caused by an imbalance of bacteria. According to the University of Hong Kong, at the suspension of 2 g/mL the extract showed a significantly inhibited effect on all tested oral pathogenic bacteria and may be considered as a potential anti- oral antimicrobial agent to control or prevent dental diseases(5).

Unfortunately, accompanied to their health effects, Mei can not be used in case of internal heat excess such as high fever with infection or cold or flu without sweat)(6) and sulfite-sensitive People should not consume fried apricot because sulfur- compounds are often added to dried foods as preservatives for prevention of oxidation, according to traditional Chinese medicine. (7).



References
(1) Flavonoid glycosides from Prunus armeniaca and the antibacterial activity of a crude extract by Rashid F1, Ahmed R, Mahmood A, Ahmad Z, Bibi N, Kazmi SU.(PubMed)(2)
(3) Antimicrobial activity of Chinese medicine herbs against common bacteria in oral biofilm. A pilot study by Wong RW1, Hägg U, Samaranayake L, Yuen MK, Seneviratne CJ, Kao R.(PubMed)
(4) The antimicrobial efficacy of Fructus mume extract on orthodontic bracket: a monospecies-biofilm model study in vitro by Chen Y1, Wong RW, Seneviratne CJ, Hägg U, McGrath C, Samaranayake LP, Kao R.(PubMed)
(5) Prunus mume extract exhibits antimicrobial activity against pathogenic oral bacteria by Seneviratne CJ1, Wong RW, Hägg U, Chen Y, Herath TD, Samaranayake PL, Kao R.(PubMed)
(6) #Healthy #Foods - Fruits - Apricot (Prunus armeniaca)
(7) Chinese Herbs – Mei or Lu E Mei (Fructus Armeniaca mume)

Thursday, April 2, 2020

Avocado-Soybean Unsaponifiables (ASUs), A Natural Treatment of Osteoarthritis, with No side Effects, Studies Showed

Avocado may be considered a functional food for the prevention and treatment of osteoarthritis, some scientists suggested.

Avocado is commercially valuable fruit cultivated in tropical climates throughout the world.

The fruit is a green-skinned, pear-shaped fruit that ripens after harvesting and native to the Caribbean, Mexico, South America, and Central America, belonging to the flowering plant family Lauraceae.

Osteoarthritis is a group of diseases involved progressive denegation of joints, including articular cartilage and subchondral bone.

According to the statistic, osteoarthritis (OA) is the most common joint disorder in the US, affecting over 10% men and 13% in women aged 60 years or older. The disease can also affect the younger population, after a traumatic injury.

Epidemiological studies suggested that symptoms progress slowly and contribute to workplace disability and reduced quality of life.

Dr. Hofmann S, the lead scientist in the team of arthritis in the examine the mechanical causes of osteoarthritis in young adults suggested that that certain conditions such as femoroacetabular impingement (a condition in which extra bone grows along one or both of the bones that form the hip joint) are a very common cause of secondary osteoarthritis (OA) in the young adults" and "
It is an important co-factor in the better recognized pre-arthritic deformities such as residual hip dysplasia (RHD), Perthes disease and slipped capital femoral epiphysis (SCFE)".


These results clearly indicated genetic mutation and mechanical deformity are major causes of osteoarthritis in younger adults besides athletic injury.

Some scientists proposed that the development of femoroacetabular impingement may be a result of a repetitive injury to the proximal femoral physis that occurs during a critical period of development.


With an aim to find a natural ingredient for the prevention and treatment of osteoarthritis, a disease associated with the progressive degeneration of joints, researchers at the Universities of Exeter and Plymouth assessed the anti-OA of the compounds Avocado/soybean unsaponifiables (ASU) which have shown some promise for OA.


By searching the database of medical literature, researchers found 4 randomized, placebo-controlled, double-blind trials of ASU.satisified the guideline and criteria.

The doses per day in the 4 studies are in the range between 300 mg and 600 mg.

3 out of 4 studies suggest that ASU is effective for the symptomatic treatment of OA.

Furthermore, the Hôpital Léopold Bellan launched a follow-up study to investigate the efficacy of preparations with avocado-soybean unsaponifiables (ASUs) in osteoarthritis (OA) patients in the hip, included 163 patients, 102 men and 61 women (mean age 63.2 +/- 8.7 years).

Participants in the study are patients with regular painful primary OA of the hip (European League Against Rheumatism 1980 criteria) and a joint space still > or = 1 mm were selected entered a prospective, multicenter, randomized, parallel group, double-blind, placebo-controlled trial of 2 years duration.

ASU treatment group showed a lesser joint space loss compared to the significantly greater loss in the placebo group.

The clinical parameters in the 2 groups did not differ significantly throughout the study.

These results indicated a significant effect of ASU against the progression of joint loss in OA patients.

Dr,. the lead scientists said, "SU significantly reduced the progression of joint space loss as compared with placebo in the subgroup of patients with advanced joint space narrowing".


Taken altogether, avocado-soybean unsaponifiables (ASUs) may have a profound effect in reducing the symptoms and progression of osteoarthritis.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Avocado-soybean unsaponifiables (ASU) for osteoarthritis - a systematic review by Ernst E.(PubMed)
(2) Symptomatic efficacy of avocado-soybean unsaponifiables (ASU) in osteoarthritis (OA) patients: a meta-analysis of randomized controlled trials by Christensen R1, Bartels EM, Astrup A, Bliddal H.(PubMed)
(3) Structural effect of avocado/soybean unsaponifiables on joint space loss in osteoarthritis of the hip by Lequesne M1, Maheu E, Cadet C, Dreiser RL. (PubMed)
(4) Mechanical causes of osteoarthritis in young adults by Hofmann S, Tschauner Ch, Graf R.(PubMed)
(5) The etiology of primary femoroacetabular impingement: genetics or acquired deformity? by Jonathan D. Packer and Marc R. Safran. (PMC)

Wednesday, April 1, 2020

Apricot, A Natural Antibiotic Which Protects the Stomach Against Chronic Gastritis Caused by Bacteria Helicobacter pylori (Hp), Scientists Show

Apricot may have a potential and substantial effect in reduced risk, progression and treatment of chronic gastritis, some scientists suggested.

Chronic Gastritis is a condition of chronic inflammation of the stomach mucosa with function to protect the stomach against overexpression of stomach acid produced for breaking down food.

The most common cause of chronic gastritis is an infection by Helicobacter pylori bacteria



Chronic gastritis can be caused by the immune system which mistakenly attacks the cells in the stomach lining and long term intake of conventional medicine, such as NSAIDs, aspirin, ibuprofen

Conventional medication used for the treatment of the condition is totally dependent on the causes of the disease, including antibiotics for bacterial infection, medicine that block acid production and promote or neutralize stomach acid.

If you experience localized symptoms of upper abdominal pain, indigestion, bloating, nausea,... and vomiting, you have chronic gastritis. Please see your doctor rule out the possibility.

The apricot tree is about 8–12 m tall and a trunk up to 40 cm diameter belongs to the family Rosaceae. Apricot is classified with the family of the plum and has yellow to orange, often tinged red on the side which is exposed to the sun.


Chemical constituents
Oleic acid, linoleic acid, palmitic.acid, glycolipids, phospholipids, benzoic acid (I), isorhamnetin (II), quercetin (III), kaempferol-3-O-beta-D-galactopyranoside (IV), isorhamnetin-3-O-beta-D-glucopyranoside (V), isoquercitrin (VI), hypericin (VII) and rutin (VIII)(3) and flavonoid glycosides, (4),

In the study of 1358 asymptomatic adults diagnosed with chronic gastritis induced by bacteria Helicobacter pylori dividing into a group with high-intake and group with low-intake of Japanese apricot (CJA), at the end of the experience, researchers found that
* Among H. pylori-positive non-elderly subjects, antibody titers were significantly lower in the high-intake group (P=0.041).

* High apricot intake group demonstrated a significantly less H. pylori bacterial load and mononuclear infiltration irrespective of the gastric site in comparison to low intake group.


Finally, the Endoscopic tissue biopsy from participants also confirmed that a high intake group shows less H. pylori bacterial load and mononuclear infiltration irrespective of gastric site.



Dr. Enomoto S, the lead author said, "Our findings strongly indicate a preventive effect of JA intake on CAG by inhibiting H. pylori infection and reducing active mucosal inflammation".


Furthermore, in the study to examine Helicobacter pylori (Hp) infection in the induction of gastric disorders, including chronic active gastritis, peptic ulcers, intestinal metaplasia and cancer with Hp-inoculated gerbils given CJA in their drinking water at concentrations of 1 and 3% for 10 weeks, researchers at the Aichi Cancer Center Research Institute, showed that* CJA intake groups exert a lower score of gastritis and mucosal hyperplasia in compared to the Hp-inoculated control group.
* PH in the glandular stomach is lower in the dose of 1 and 3% CJA in compared to Hp-inoculated control groups.


These results indicated that CJA at doses of 1 and 3% has a strong effect in protecting the stomach lining against overexpression of stomach acid.

In the final report, Dr. Otsuka T, the lead scientist wrote, "These findings suggest that suppressive effects on gastric cancer development might also be expected as a result of decreased numbers of Hp and improvement of Hp-induced chronic active gastritis on the administration of CJA.".


Taking all together, Apricot fruit juice may be used as a natural antibiotic functional food for the treatment of chronic gastritis caused by Helicobacter pylori bacteria without inducing any side effects.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

References
(1) Inhibitory effects of Japanese apricot (Prunus mume Siebold et Zucc.; Ume) on Helicobacter pylori-related chronic gastritis by Enomoto S1, Yanaoka K, Utsunomiya H, Niwa T, Inada K, Deguchi H, Ueda K, Mukoubayashi C, Inoue I, Maekita T, Nakazawa K, Iguchi M, Arii K, Tamai H, Yoshimura N, Fujishiro M, Oka M, Ichinose M.(PubMed)
(2) Suppressive effects of fruit-juice concentrate of Prunus mume Sieb. et Zucc. (Japanese apricot, Ume) on Helicobacter pylori-induced glandular stomach lesions in Mongolian gerbils by Otsuka T1, Tsukamoto T, Tanaka H, Inada K, Utsunomiya H, Mizoshita T, Kumagai T, Katsuyama T, Miki K, Tatematsu M.(PubMed)
(3) [Studies on the chemical constituents of flowers of Prunus mume].[Article in Chinese] by Zhang QH1, Zhang L, Shang LX, Shao CL, Wu YX.(PubMed)
(4) Flavonoid glycosides from Prunus armeniaca and the antibacterial activity of a crude extract.
Rashid F1, Ahmed R, Mahmood A, Ahmad Z, Bibi N, Kazmi SU.(PubMed)

Tuesday, March 31, 2020

Healthy Food Onion Protects the Healthy Cell Against Cyto and Geno-Toxicity

Cytotoxicity is the process that kills cells by inducing toxic substances.

Cancer cytotoxicity is the stage of killing cancer cells by toxicity with or without inducing side effects.

Most cases of cytotoxicity of a substance are to determine the potential toxicity of the quality of the substance, including plant extracts or biologically active compounds isolated from plants.

In other words, the aim of the cytotoxic studies is to find the minimal quality that is essential for the successful development of pharmaceutical or cosmetic preparation that induces cellular toxicity for the treatment of cancer.


Before the preparation can be used in humans, bioassays associated with a number of different cell lines in vitro and vivo have been used to assess the cytotoxicity of many herbal plants, including those of African medicinal plants.

Free radicals have also been found to induce cytotoxicity to cause cancer death by oxidative stress.

Dr. Clifford Fong wrote, "An analysis of the cytotoxicity data for a wide range of anti-cancer drugs applied to triple-negative breast cancer (TNBC) cells and ovarian cancer cells under normoxic, hypoxic and anoxic conditions have shown that free radical forms of the drugs are involved".

And " This finding is consistent with the known involvement of oxidative stress in the TNBC and ovarian cancer cells. A mechanism to explain the formation of these drug-free radicals and how they can be involved in oxidative stress is proposed".

Genotoxicity is the term associated with chemical agents that damages the genetic information within a cell, causing mutations of cell DNA, a major cause of cancer.


Not all genotoxicity is mutagenicity, However, all mutagens are genotoxic.

The onion is a plant in the genus Allium, belonging to the family Alliaceae, a close relation of garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.


Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.

On finding a potential compound for the treatment of cancer, researchers examined the effect of an onion extract on cyto- and genotoxicity in human lymphocytes treated with bleomycin (BLM), a radiomimetic agent.

In radiation exposure -induced oxidative DNA damage in the increased risk of cancer, the risk the richest sources of dietary flavonoids found in onion inhibited the frequency of micronuclei (MN) and DNA damage following treatment with BLM, according to the cytokinesis-blocked micronucleus assay and a single cell gel electrophoresis assay.

Phytochemicals in the onion showed a significant increase in cell viability in lymphocytes exposed to BLM compared to cells treated with BLM alone.

Onion also suppressed the increased frequency of BLM induced MN and DNA damage in a dose-dependent manner evidenced by lymphocytes viability pretreated with onion extract (10 and 20 μL/mL).

Moreover, the frequency of BLM-induced MN was decreased at all doses of BLM and DNA damage was decreased by the administration at 3 μg/mL of BLM.

Based on the findings, researchers said, "onion extract may have protective effects against BLM-induced cyto- and genotoxicity in human lymphocytes".

Taken altogether, onion processed abundantly bioactive compounds may be considered a remedy for the prevention and treatment of cytotoxicity and genotoxicity, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Protective Effect of Onion Extract on Bleomycin-Induced Cytotoxicity and Genotoxicity in Human Lymphocytes by Cho YH1,2, Lee JW3, Woo HD4, Lee S5, Kim YJ6, Lee Y7, Shin S8, Joung H9, Chung HW. (PubMed)
(2) Evaluation of cytotoxicity and genotoxicity of Hancornia speciosa latex in Allium cepa root model by Ribeiro TP1, Sousa TR1, Arruda AS1, Peixoto N1, Gonçalves PJ2, Almeida LM. (PubMed)
(3) Free radicals in chemotherapy-induced cytotoxicity and oxidative stress in triple negative breast and ovarian cancers under hypoxic and normoxic conditions by Clifford Fong (HAL)

Monday, March 30, 2020

Tomatoes, the Natural Prevention and Treatment of Hypercholesterolemia

Hypercholesterolemia is a condition of high blood cholesterol. A condition is a form of hyperlipidemia or high blood lipids.

The cause of hypercholesterolemia is a result of overexpression of low-density lipoprotein with reduced levels of high-density lipoprotein in the blood.

Believe it or not, cholesterol produced by the liver or from outside sources is essential for the building of strong cell membranes, the production of steroid hormone and vitamin D.

However, overexpression of blood cholesterol-induced hypercholesterolemia has been found to exhibit the risk of cardiovascular disease and diabetes.

Compared to hypercholesterolemia, the healthy levels of LDL/HDL are any numbers that are less than 4.

There is no single cause of hypercholesterolemia. Epidemiologically, diet, obesity, genetic preposition and medical conditions such as diseases such as type 2 diabetes and an underactive thyroid are some the prevalent factors associated with the risk of the condition.

According to the statistics, over 34 million American adults are living with elevated blood cholesterol levels (higher than 240 mg/dL). ...


The most common inherited form of high blood cholesterol is called familial hypercholesterolemia found in 1/500 people.

By adopting a healthy lifestyle and moderate exercise, you may do just fine without medication.


Tomato is red, edible fruit, genus Solanum, belongs to family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.

With an aim to find a natural ingredient or whole food for the treatment of hypercholesterolemia, researchers compared the effect of dried tomato, grape and apple pomace (5% in diet) on the cholesterol levels in serum in an animal model

The study included selected male Wistar rats fed a cholesterol diet (0.3%) shortly after weaning followed by administration of individual fruits contained 47.2, 67.0 and 46.2 g of total dietary fiber per 100 g of dry matter for tomato, grape and apple pomace, respectively.

Compared to apple pomace reduced the liver cholesterol by 11% tomato showed a better-reduced cholesterol level in the liver by 15%


Tomatoes and other tested pomace species reduced cholesterol content in the heart by 18-21%.

Only tomatoes exerted a significant effect on the levels of triacylglycerol content in the heart compared to other tested pomaces.

All products strongly reduced (up to the half of the original value) the activity of enzymes HMG-CoA reductase associated with the production of cholesterol in the liver and increased the fractional catabolic rate of plasma cholesterol by 60-120%.

In rats fed with hypercholesterolemic feed and treated with lycopene orally by gavage at the dose of 5, 25, 45, 65, 85, and 105, 125 mg/kg/bw-1/d-1, researchers found that injection of all doses of lycopene exerted a statistical significance in reducing the levels of cholesterol observed by inverse U shape at the 4 weeks of the experiment.

Furthermore, serum lycopene concentration was negatively correlated with the levels of serum TC, LDL-C, particularly in the cerebral LDL-C.



In other words, serum lycopene found in the tested model showed a strong effect against brain cholesterol in facilitating neuron damage.

Dr. Wang W, the lead scientist said, "These results suggested an inverse U-shape relation between dose and serum concentration of lycopene, and intermediate doses were most effective to protect cerebral vessels and neurons from being damaged by hyperlipidemia".

Taken altogether, tomatoes processed high amounts of lycopene may be considered supplements for the prevention and treatment of hypercholesterolemia, pending to the confirmation of the larger sample size and multicenter human study.

Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.



Sources
(1) The effect of dried tomato, grape and apple pomace on the cholesterol metabolism and antioxidative enzymatic system in rats with hypercholesterolemia by Bobek P1, Ozdín L, Hromadová M. (PubMed)
(2) The dose-response effect of lycopene on cerebral vessel and neuron impairment induced by hyperlipidemia by Wang W, Yang W, Shen Z, Wen S, Hu M. (PubMed)

Sunday, March 29, 2020

Apricot, the Potential Anti Breast Cancer Remedy, Scientists Say

Finding a cure for breast cancer from the botanical plants without inducing side effects has been a lifetime dream of many scientists. Unfortunately, as of today, the finding is still ongoing without much success.

However, according to some studies, apricot, the edible fruit may be the next pharmaceutical target to extract potential ingredients for the cure for breast cancer.

Breast cancer is a medical and chronic condition as the result of irregular cell growth originated from the breast tissue. why women in the same health conditions, family history, and race, some are prone to develop the early onset of the disease while others do not.

Breast cancer is caused by the alternation of DNA of the cells in the breast tissue. Epidemiologically, certain prevalent factors are associated with an increased risk of the disease.

According to the probability for women to develop or die from breast cancer provided by the Canadian Cancer Statistics publication, the lifetime risk of a woman to develop is 1/8 and 1/31 of them will die from the disease.

The 5 years survival rate of the early stage of breast cancer is 100% compared to much less in the advanced stage.

Therefore, women with higher risk such as genetic preposition of gene BRAC1 and 2 should have their breast mammogram taken every year.


More importantly, Dr. Zainab Taha, the lead author in the study "The Role of Diet and Lifestyle in Women with Breast Cancer: An Update Review of Related Research in the Middle East" wrote,
"There is an alarming epidemic of obesity among women in most of the EMR countries, especially Gulf Coopers action Council (GCC) countries. The rise in the new breast cancer cases among women could be attributed to excess body weight. Their dietary pattern, which correlates with obesity, can be an important factor in the etiology of cancer.".

These results\ strongly suggested that diet and lifestyle associated with the onset of obesity are major contributors to the early onset of breast cancer.

In other words, if you follow a healthy diet with a lot of fruits and vegetables, whole grain with less in saturated and trans fat, red meat and processed and lifestyle with moderate exercise, you are at the lower end in the risk factor scale of breast cancer.

The apricot tree is about 8–12 m tall and a trunk up to 40 cm diameter belongs to the family Rosaceae. Apricot is classified with the family of the plum and has yellow to orange, often tinged red on the side which is exposed to the sun.

Chemical constituents of apricot include
Oleic acid, linoleic acid, palmitic.acid, glycolipids, phospholipids, benzoic acid (I), isorhamnetin (II), quercetin (III), kaempferol-3-O-beta-D-galactopyranoside (IV), isorhamnetin-3-O-beta-D-glucopyranoside (V), isoquercitrin (VI), hypericin (VII) and rutin (VIII)(a) and flavonoid glycosides, (b),

In the reaffirming the MK615, an extract mixture containing hydrophobic substances from Japanese apricot. anti-cancer possibility, researchers at the Dokkyo University School of Medicine conducted an evaluation to examine the antineoplastic effects of MK615 against breast cancer cells.
The experiment includes 2 breast cancer cell lines, MDA-MB-468 (MDA) and MCF7, were cultured with (600, 300, and 150 mug/mL) or without MK615.

After 72 hours of incubation, researchers showed that

* MK615 inhibited the growth of MDA and MCF7 in a dose-dependent manner.

* The percentage growth inhibition of MDA at dosages of 600, 300, and 150 mg/mL was 59.2%, 52.4%, and 23.3%, respectively, and that for MCF7 was 83.5%, 52.7%, and 16.6%, respectively.

* MK615 treatment included massive vacuolization in the cytoplasm and apoptotic changes in the nucleus.

* Cell cycle analysis showed that MK615 increased the proportion of cells in the G2-M phase in both MDA (7.8-11.7%) and MCF7 (8.1-18.7%), and finally both cell lines became apoptotic.

These results suggested MK615 effectively inhibits the growth of breast cancer cells in vitro, through cell cycle arrest and apoptosis.


Furthermore, in the concerns of breast cancer continued to cause high cancer death rates among women worldwide, researchers at the joint study led by the Universiti Sains Malaysia launched an evaluation to examine the plant-based products which have demonstrated anticancer potential through different biological pathways including modulation of the immune system. Immunomodulatory properties of medicinal plants have been shown to mitigate breast cancer cell growth.


Out of the medical plants selected including Glycyrrhiza glabra, Uncaria tomentosa, Camellia sinensis, Panax ginseng, Prunus armenaica (apricot), Allium sativum, Arctium lappa and Curcuma longa, malic acid and quinic acid isolated from apricot exerted a significant activity in regulating the immune system potentially applicable in breast cancer treatment via anti-inflammatory and lymphocytes activation.


Taken all together, apricot may be considered a functional food for the prevention and a secondary therapy combined conventional medicine for the treatment of breast cancer.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(a) [Studies on the chemical constituents of flowers of Prunus mume].[Article in Chinese] by Zhang QH1, Zhang L, Shang LX, Shao CL, Wu YX.(PubMed)
(1) New antineoplastic agent, MK615, from UME (a Variety of) Japanese apricot inhibits growth of breast cancer cells in vitro by Nakagawa A1, Sawada T, Okada T, Ohsawa T, Adachi M, Kubota K. (PubMed)
(2) The Immunomodulatory Potential of Selected Bioactive Plant-Based Compounds in Breast Cancer: A Review by Baraya YS1, Wong KK2, Yaacob NS. (PubMed)
(3) The Role of Diet and Lifestyle in Women with Breast Cancer: An Update Review of Related Research in the Middle East by Zainab Taha1 and Sakina E. Eltom. (PMC)

Saturday, March 28, 2020

Strawberries Reduce Risk and Treatment of Type 2 Diabetes

The rise of obesity-associated with the increase in the incidence of Type 2 diabetes has been a significant burden on health care systems in many countries.

Strawberry processed abundant phytochemicals may be the next target for pharmaceutical companies to extract a single ingredient for the treatment of type 2 diabetes, some scientists suggested.

Type 2 diabetes is the medical condition characterized by insufficient insulin entering the bloodstream to regulate the glucose as the results either cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol.

Researchers do not why people in similar health conditions, diet and family history are susceptible to the development of insulin resistance, the early stage of diabetes while others do.

Some researchers suggested that genetic proposition and unhealthy lifestyle accompanied physical activity are the most common risk factors associated with the onset of type 2 diabetes.

Dr. Karla C. Paz-Salinas, the lead author in the study "Do People with Type 2 Diabetes Think They are Unhealthy?" wrote, "A healthy lifestyle and understanding of diabetes management are important factors for delaying the onset of comorbidities associated with Type 2 diabetes".

In genetic preposition front, researchers at the Medical College of Wisconsin, said, "Very few T2D risk genes were identified using candidate gene and linkage-based studies, but the advent of genome-wide association studies has led to the identification of multiple genes, including several that were not previously known to play any role in T2D. Highly genes, for example, TCF7L2, KCNQ1, and KCNJ11, are discussed in greater detail".



We can not prevent the onset of type 2 diabetes caused by a genetic mutation, however, the risk of type 2 diabetes can be reduced substantially and type 2 diabetes can be easily managed if we are following the healthy lifestyle that processes the diet high in fruits and vegetable, less in saturated and trans fat, red meat and processed food with moderate exercise.


Strawberry is a genius of Fragaria × ananassa belongs to the family Roseaceae. They have been grown all over the world with a suitable climate for commercial profits and for health benefits.

The major chemical compounds of strawberry include anthocyanin and ellagitannins and p-Hydroxybenzoic acid, p-coumaric acid, ellagic acid, cyanidin-3-glucoside, pelargonidin-3-glucoside, kaempferol, quercetin, and myricetin.

In the finding of a natural ingredient for the treatment of diabetes with no side effects, researchers at the University of California launched a study to examine the anti-inflammatory and blood glucose (BG)-regulating capacity of strawberries in a mouse model of diet-induced obesity.

In a total of thirty-six male C57BL/6J mice were included in the study randomly divided into four groups (nine mice per group), including mice fed a low-fat diet (LF, 13 % fat), the LF supplemented with 2·6 % freeze-dried strawberry powder (LFSB), a high-fat diet (HF, 44 % fat) or the HF supplemented with 2·6 % strawberry powder (HFSB).

The dietary intake of SB approximated one human serving of strawberries


Before the administration of strawberry powder, a blood sample of HF group showed an increased non-fasted BG, insulin, soluble intracellular adhesion molecule-1, the important biomarkers for inflammatory processes involving activation or damage to cells, E-selectin, leptin, resistin, and plasminogen activator protein-1, the indication of the inflammatory process.

High dietary fat decreased IL-4 production, an anti-inflammatory cytokine from activated splenocytes, the white blood cells.

The levels of BG concentrations were lower in the mice supplemented with SB (10·64 mmol/l) compared to the non-supplemented mice.

BG values were approximately 6·5 % lower in the supplemented mice.

These results firmly supported a promising role for dietary strawberries in reducing the risks associated with obesity and diabetes and regulating the levels of inflammatory markers in non-obese individuals.

The study was published Nov 28 on the US National Library of Medicine and National Institutes of Health. You can view the abstract by clicking the link in the resources box.

Please note that strawberry contains a measured amount of oxalates, if you have kidney disease, please check with your doctor before applying.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Dietary strawberry powder reduces blood glucose concentrations in obese and lean C57BL/6 mice, and selectively lowers plasma C-reactive protein in lean mice by Parelman MA, Storms DH, Kirschke CP, Huang L, Zunino SJ.(PubMed)
(2) Do People with Type 2 Diabetes Think They are Unhealthy? by A Cross-Sectional Study in Celaya, Mexico by Karla C. Paz-Salinas,1 Nicolas Padilla-Raygoza,1,2 Silvia C. Delgado-Sandoval,1,2Georgina Olvera-Villanueva,1,2 and Ma Laura Ruiz-Paloalto. (PMC)

Friday, March 27, 2020

Healthy Food Onion Protects the vascular endothelial Functioning Against Cardiovascular Disease

Vasoprotection is the process to improve the function of the blood vessels, including the use of the herbal and natural remedy.

Blood vessels are the tubular structure including a vein, artery, or capillary which carries the blood through the tissues and organs pumped by the heart.

There 3 main types of the blood vessel are arteries that deliver oxygen-rich blood from the heart to the tissues and organs of the body. Damage of arteries may induce coronary artery disease associated with the narrowing or blockage of the coronary arteries due to plaques accumulated on the arterial wall.

The veins that carry blood toward the heart. Chronic venous insufficiency (CVI) is a common condition associated with disease of the veins that affects up to 20 percent of adults.

The capillaries or the smallest blood vessels has been found to induce systemic capillary leak syndrome (SCLS) is a rare acquired disorder.

Endothelial dysfunction is a condition characterized by the damage of the vascular endothelium, the thin layer of cells that lines blood vessels, a leading cause of the cardiovascular disease (CVD).

In other words, the vascular endothelium dysfunction reduced the function of targeting free radical that lead to the onset of oxidative stress.

Most common risk factors associated with vascular endothelium dysfunction are impaired vasodilation, deficiency of nitric oxide, and inflammation, and thrombosis.

Dr. Hirata Y. at The University of Tokyo.wrote, "Vascular endothelial dysfunction reflected by reduced nitric oxide (NO) availability is certainly the causative factor or promoting mechanism of arteriosclerosis. It is necessary to detect endothelial dysfunction at an early stage using appropriate methods, and to choose a treatment for the recovery of endothelial function".

And, "There are nonpharmacological and pharmacological therapies to attain endothelial repair. The former includes bodyweight reduction, aerobic exercise, and restriction of salt intake, while the latter includes the use of renin-angiotensin system inhibitors, calcium antagonists, some types of beta-blockers, statins, erythropoietin, tetrahydrobiopterin, and antioxidants".

The onion is a plant in the genus Allium, belongings to the family Alliaceae, a close relation of garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.

Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.
On finding a potent ingredient which processes vasoprotective activity researchers examined quercetin, a dietary polyphenol found abundantly in onion on vascular endothelial dysfunction (VED).

Epidemiologically, quercetin showed significant activity against the VED complication in the induction of oxidative stress, impaired vasodilation, platelet aggregation, and monocyte adhesion leading to the early event of morbidity and mortality in patients with cardiovascular disease (CVD).

Quercetin efficacy that protects against VED and decreases CVD risk was attributed to its antioxidant, vasodilatory, anti-platelet, and anti-atherogenic activities.

Futhermore, in vitro, quercetin exerted multiple actions on the NO-guanylyl cyclase pathway associated with the smooth muscle tone in bronchi or vessels, endothelium-derived hyperpolarizing factor(s) and endothelin-1 involved in vasoconstriction and endothelial function.

Moreover, the phytochemical also protected endothelial cells against apoptosis.

In vivo, quercetin prevented endothelial dysfunction by reducing blood pressure, oxidative stress and end-organ damage in hypertensive animals.

In other words, regular intake of quercetin improves the endothelium functioning against the risk of VED inducing cardiovascular disease, particularly in patients with hypertension and ischemic heart disease.

Taken altogether, onion processed a higher mount of quercetin may be considered a remedy for the prevention and treatment of vascular endothelial dysfunction, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.


Sources
(1) Vasoprotective activities of quercetin by Richard S Bruno. (Research Gate)
(2) Endothelial function and cardiovascular disease: effects of quercetin and wine polyphenols by Perez-Vizcaino F1, Duarte J, Andriantsitohaina R. (PubMed)
(3) Diagnosis and treatment of endothelial dysfunction in cardiovascular disease by Hirata Y1, Nagata D, Suzuki E, Nishimatsu H, Suzuki J, Nagai R. (PubMed)

Thursday, March 26, 2020

Strawberries, The Functional Food Which Inhibits the Risk Factors of the Onset of Atherosclerosis, Researchers Suggest

Strawberries may be considered a functional food that blocks the plaque accumulated in the arteries, causing atherosclerosis, some scientists suggested.

Atherosclerosis is a medical condition of heart disease characterized by plaque building up in the inner wall of the arteries.

Where arteries are blood vessels that carry oxygen and nutrient-rich blood to the heart and other organs and tissue of the body and plaque is the substance made up mostly with fat, cholesterol, calcium.

According to the statistics, atherosclerosis causes 32% of deaths of heart disease. The prevalence rate of the disease onset among adults of 20 years and above is 13.8%.

Dr. Singh RB, the lead author in the assessment of diet and exercise and lifestyle on risk of atherosclerosis conducted a randomized, single-blind, controlled trial, 621 patients assigned either intervention diet A (group A, 310 patients) or control diet B (group B, 311 patients) for a period of 24 weeks.

Where participants of group A are received: (1) a diet with a higher percentage of calories from fruits and vegetables and complex carbohydrates; (2) a higher polyunsaturated/saturated fat ratio diet; and (3) a larger amount of soluble dietary fiber, antioxidant vitamins and minerals, and low saturated fat and cholesterol than group fB. Group A patients also did more physical and yogic exercises than group B.

After 24 weeks of intervention, he wrote. " There was a significant decrease in serum total cholesterol (13.3%), low-density lipoprotein cholesterol (16.9%), triglycerides (19.2%), fasting blood glucose (19.5%) and blood pressures (11.5/6.2 mm Hg) in the intervention group compared with initial levels and changes in group B".

These result suggested that a healthy diet accompanied by moderate exercise are the major factors that can substantially reduce the risk of atherosclerosis. In other words, people who follow the Western diet with physical inactivity are at higher risk of the onset of the disease.


Strawberries are a genius of Fragaria × ananassa belonging to the family Roseaceae.

They have been grown all over the world in a suitable climate for commercial profits and health benefits.

The major chemical compounds of strawberry include anthocyanin and ellagitannins and p-Hydroxybenzoic acid, p-coumaric acid, ellagic acid, cyanidin-3-glucoside, pelargonidin-3-glucoside, kaempferol, quercetin, and myricetin.

Intake of strawberry daily to improve the potent antioxidant status in the body can reduce cardiovascular risk factors, such as elevated blood pressure, hyperglycemia, dyslipidemia, and inflammation in limited studies.

Dr. Basu A, the team leader at the Oklahoma State University, Stillwater study showed that freeze-dried strawberry supplementation improves blood pressure, impaired glucose, dyslipidemia, or circulating adhesion molecules in obese subjects with metabolic syndrome, thereby lowering cardiovascular risk factors in these subjects suggested.

The randomized controlled trial included 27 subjects with metabolic syndrome (2 males and 25 females; body mass index, 37.5 +/- 2.15 kg/m(2); age, 47.0 +/- 3.0 years [means +/- SE]) consumed 4 cups of freeze-dried strawberry beverage (50 g freeze-dried strawberries approximately 3 cups fresh strawberries) or equivalent amounts of fluids (controls, 4 cups of water) daily for 8 weeks.

Strawberry supplementation intake significantly decreased total and low-density lipoprotein cholesterol (5.8 +/- 0.2 to 5.2 +/- 0.2 mmol/L and 3.5 +/- 0.2 to 3.1 +/- 0.1 mmol/L, respectively [means +/- SE], P < .05) and low-density lipoprotein particles compared to controls at the week 8.

Furthermore, strawberry supplementation also decreased circulating levels of vascular cell adhesion molecule-1 vs controls at the end of the study.

The team at the final report said, "short-term freeze-dried strawberry supplementation improved selected atherosclerotic risk factors, including dyslipidemia and circulating adhesion molecules in subjects with metabolic syndrome".

In additional examing the therapeutic roles of strawberries, blueberries, and cranberries in metabolic syndrome, a prediabetic state characterized by several cardiovascular risk factors, Dr. Basu A said, "strawberries lowering total and LDL-cholesterol, but not triglycerides, and decreasing surrogate biomarkers of atherosclerosis (malondialdehyde and adhesion molecules)".

Strawberry also extended a lowering systolic and diastolic blood pressure and lipid oxidation and improving insulin resistance but in the lesser effect compared to the blueberry

Cranberry juice selectively decreasing biomarkers of lipid oxidation (oxidized LDL) and inflammation (adhesion molecules) in metabolic syndrome compared to lesser effect in those of strawberry.

The tested berries demonstrated a potential effect in up-regulation of endothelial nitric oxide synthase activity in the protection of the cardiovascular system, reduction of renal oxidative damage, and inhibition of the activity of carbohydrate digestive enzymes or angiotensin-converting enzyme in controlling the blood pressure by regulating the volume of fluids in the blood.


Taken all together, strawberry may be considered a function\al food for the prevention of atherosclerosis and combined with the primary therapy for the treatment of the disease.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.



Reference
(1) The strawberry: composition, nutritional quality, and impact on human health. by Giampieri F, Tulipani S, Alvarez-Suarez JM, Quiles JL, Mezzetti B, Battino M.(PubMed)
(2) Phenolic Composition of Strawberry Genotypes at Different Maturation Stages(ACS Publication)
(3) Strawberries decrease atherosclerotic markers in subjects with metabolic syndrome.
Basu A, Fu DX, Wilkinson M, Simmons B, Wu M, Betts NM, Du M, Lyons TJ.(PubMed)
(4) Strawberries, Blueberries, and Cranberries in the Metabolic Syndrome: Clinical Perspectives.
Basu A, Lyons TJ.(PubMed)
(5) Effects of diet and lifestyle changes on atherosclerotic risk factors after 24 weeks on the Indian Diet Heart Study by Singh RB1, Singh NK, Rastogi SS, Mani UV, Niaz MA. (PubMed)

Wednesday, March 25, 2020

Whole Food Tomato and Its Bioactive Compound Lycopene Protect the Obese Patients Against Complications

Obesity is a progressive chronic disease, associated with abnormal or excessive fat accumulation in the body.

People who have a BMI of over 30 is considered to be obese.
According to the statistics provided by Obesity Cabada, the rate of obesity has increased at an alarming rate in Canada over the past few decades.

Approximately over 30% of Canadian adults are considered obese that may require medical support to manage their disease.

Epidemiologically, type 2 diabetes, high blood pressure, heart disease, stroke, arthritis, cancer and other major health problems have been found in most obese patients, causing concern to the scientist community in the health care system.

Believe it or not, obesity has been found contributing to one 10 premature deaths among Canadian adults age 20 to 64. As of today, the health care system in Canada has spent between $5 billion and $7 billion for the treatment of obese related complications.

Furthermore, obesity is associated with increased mortality and a number of complications including diabetes, heart disease, dementia, and cancer.

And, the commitment of reduced weight through a healthy diet accompanied by moderate exercise has been proposed to target the complications.

Out of many risk factors associated with the onset of obesity, the social economy may have some implication involved in the onset of the disease.

Dr. BRIAN HOULE, wrote in the article "How Obesity Relates to Socioeconomic Status" "...obesity rose with a nation’s economic development, but also that socioeconomic status as it related to obesity changed. In lower-income countries, people with higher SES were more likely to be obese. Conversely, in high-income countries, those with higher SES were less likely to be obese".

And, "Why the reversal? It may be that in lower-income countries, higher SES leads to consuming high-calorie food and avoiding physically tough tasks. But in higher-income countries, individuals with higher SES may respond with healthy eating and regular exercise".

Tomato is red, edible fruit, genus Solanum, belongs to family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.

On finding a natural and potential compound for the treatment of obesity, researchers review the link of high intake of lycopene or tomatoes products in the risk for metabolic diseases by comparing the effect of lycopene and tomato powder on obesity-associated disorders.

The study included selected Male C57BL/J6 mice randomly assigned into four groups to receive: control diet (Chigh-fat fat diet (HFD), high fat diet supplemented with lycopene or with tomato powder (TP) for 12 weeks.

In mice treated with HFD, lycopene and TP supplementation significantly improve the obese complications caused by adiposity index, organ, and relative organ weights, serum triglycerides, free fatty acids.

Furthermore, lycopene and TP supplementation also 8-iso-prostaglandin GF2α associated with an increased risk of heart disease and improved glucose homeostasis, against the onset of abnormal blood glucose.

Furthermore, Lycopene and TP supplementation prevented HFD-induced hepatosteatosis and hypertrophy of adipocytes associated with patients of obesity.

Moreover, lycopene and TP also decreased HFD-induced the production of proinflammatory cytokines in the liver and in the epididymal adipose tissue found in obese subjects.

According to the tested assay, lycopene and TP anti-inflammatory effects were attributed to the inhibition of the protein involved promotion of the expression of inflammation in adipose tissue.

Based on the findings, lycopene, and TP protected significantly obese subjects against the onset of obesity complications.

Dr. Fenni S after taking other factors into account wrote, "These results suggest that lycopene or TP supplementation display similar beneficial health effects that could be particularly relevant in the context of nutritional approaches to fight obesity-associated pathologies".

Taken altogether, tomatoes processed a high amount of lycopene may be considered whole food for the prevention and treatment of diseases associated with obesity, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca



Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.


Sources
(1) Lycopene and tomato powder supplementation similarly inhibit high-fat diet induced obesity, inflammatory response, and associated metabolic disorders by Fenni S1,2, Hammou H2, Astier J1, Bonnet L1, Karkeni E1, Couturier C1, Tourniaire F1, Landrier JF. (PubMed)