Cruciferous Vegetables Inhibit the Risk of Kidney Cancer

The kidneys are two bean-shaped organs located just below the rib cage, one on each side of your spine.

The kidneys formed a second detoxed organ in the body after the liver not only plays an essential role in regulating electrolytes, blood pressure, maintains acid-base balance, produces hormone calcitriol, renin, and erythropoietin,... but also filters blood that passes into the tubules.

In the urinary system, kidneys reabsorbed some necessary substances back into the blood, while waste, such as urea and ammonium are deposited into the pelvis then into the ureter to the bladder for secretion.

Kidney Cancer is a medical condition characterized by irregular cell growth in the tissue of kidneys.
At the later stage, the cancerous cells may travel a distance way to infect other organs' tissues.
For example, if kidney cancer spreads to the lung is called kidney cancer with lung metastases.

At the very early stage of the kidney, cancerous tumors are localized on the surface of the kidneys.


The most common type of kidney cancer is renal cell cancer.

The causes of kidney cancer are unknown. Some researchers suggested that genetic mutation, cigarette smoking, obesity, family history,..... and exposed to chemicals, such as asbestos and benzene are all associated with increased risk of kidney cancer.

Kidney cancer affects only 2% of the general population. Approximately 14 percent of the US population suffer some forms of chronic kidney disease (CKD), including 661,000 cases of kidney failure.

Cruciferous vegetables are a group of vegetables, belongings to the family Brassicaceae (also called Cruciferae) with many genera, species, and cultivated all over the world in suitable climate for commercial profits, including cauliflower, cabbage, kale, garden cress, bok choy, broccoli, Brussels sprouts, and green leafy vegetables.

On finding a potential remedy for reducing the risk chronic diseases, researchers examined the effects of cruciferous vegetable consumption in the risk of renal cell carcinoma.

The meta-analysis included 3 cohort and 7 case-control studies retrieved via both computerized searches and review of references.

According to the summary of the calculation of the relative risks (RRs) with 95% confidence interval (CI) for the highest vs. the lowest consumption of cruciferous vegetables,

in cruciferous vegetables consumption group (RR = 0.73; 95% CI, 0.63-0.83) and subgroup of case-control studies (RR = 0.69; 95% CI, 0.60-0.78), compared to statistically insignificant in cohort studies (RR = 0.96; 95% CI, 0.71-1.21).

No heterogeneity and publication bias was detected across studies.


In other words, the meta-analysis supported the cruciferous vegetable consumption for decreasing the risk of renal cell carcinoma.

However, because of the limited number of studies, researchers said, "further well-designed prospective studies and researches need to be conducted to better clarify the protective effect of cruciferous vegetables on renal cell carcinoma and potential mechanism".


Taken altogether, cruciferous vegetables may be considered functional remedies for the prevention of kidney cancer, pending to the confirmation of the larger sample size and multicenter human study.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Cruciferous vegetables consumption and risk of renal cell carcinoma: a meta-analysis by Liu B1, Mao Q, Wang X, Zhou F, Luo J, Wang C, Lin Y, Zheng X, Xie L. (PubMed)