The Best Smoothie of Green tea, Grape and Sweet Potato for Prevention and Treatment of Kidney Stones caused by Medullary sponge kidney

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Medullary sponge kidney is a contingent disorder of kidney disease resulted of cystic dilatation of the collecting tubules in one or both kidneys, leading to increased risk of forming of kidney stone and urinary track infection. Most Medullary sponge kidney can be treated by minimally invasive percutaneous nephrolithotomy in the treatment of medullary sponge kidney patients with complex renal calculi(*).

The smoothie for reduced risk and treatment of Kidney stone caused by Medullary sponge kidney
Yield: 2 servings (about 8 ounces each)
1 gram of formula RRF(you cam buy them in any Chinese herbal store)
1 cup grape
1/2 cup sweet potato
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding the natural ingredients for reduced symptoms and treatment of Kidney stone is considered as a dream of many scientist to replace the long usage adverse effect of conventional medicine.
Unfortunately, many compounds found effective in initial studying failed to confirm the potentials in large sample size and multi center.
Hydronephrosis is a health condition of kidney swelling caused by urine retention. According to the China Medical University, in patients with ureteral stones and colic, a majority (nearly 71 %) will demonstrate only mild hydronephrosis(1).
Kidney stone is a tiny mineral and acid salts form inside your kidneys. recent study back by some renowned institution suggested that green tea(2) may have a potential in reduced risk and treatment of forming of kidney stone.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. According to the Seoul National University Hospital, epigallocatechin gallate (EGCG), a main constituent of green tea polyphenols processed an inhibitory effect on urinary stone formation, through its anti-oxalate effect(2).

Treatment of Green tea in a total of 120 Wistar rats study also exhibited decreased urinary oxalate excretion and calcium oxalate deposit formation due to antioxidative effects(3).

Dr. Kanlaya R and colleagues in the study led by the Mahidol University said, " EGCG in reducing COM crystal deposition in previous animal models of kidney stone disease. Thus, EGCG may be useful for the prevention of new or recurrent stone formation"(4).

Gallotannin, class of molecules belongings to the hydrolysable tannins found abundantly in grape and blueberry may also exert protective effect against forming of kidney stone(5). According to the Kyung Hee University, gallotannin suppressed calcium oxalate crystal binding and oxalate-induced oxidative stress in renal epithelial cells by upregulating antioxidant expression(5).

Furthermore, the 1,2,3,4,6-Penta-O-galloyl-beta-D-glucose derivative of gallotannin, attenuated  renal crystallization and oxidative renal cell injury for treatment of nephrolithiasis(6).

Vitamin E, a fat soluble vitamin found abundantly in sweet potato may also induced protective effect against kidney stone forming through it antioxidant in involvement of free radical-mediated lipid peroxidation-induced membrane damage in the pathogenesis of calcium oxalate crystal deposition and retention(7).

Dr. Thamilselvan S and Dr. Menon M. said, " excess vitamin E completely prevented calcium oxalate deposition, by preventing peroxidative injury and restoring renal tissue antioxidants and glutathione redox balance"(8).

According to the National Taiwan University Hospital, Vitamin E attenuates crystal formation in rat kidneys through educing calcium oxalate accumulation via attenuation of tubular cell death and enhancement of the defensive roles of osteopontinin (OPN), and Tamm-Horsfall protein as crystallization inhibitors(9).

The combination of Green tea, Grape and Sweet Potato smoothie may hold a key in further studies in production of an effective natural ingredients for prevention and treatment of hydronephrosis caused by Kidney Stones without inducing adverse effects.

People who are at increased risk of hydronephrosis caused by Kidney Stones due to drinking habit, family history .....should drink at least one cup daily and people with hydronephrosis caused by Kidney Stones should drink the juices at least 3 times a day, depending to digestive toleration.
Change of life style and diet pattern are also recommended.

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References
(*) Safety and efficacy of minimally invasive percutaneous nephrolithotomy in the treatment of patients with medullary sponge kidney by Sun H1, Zhang Z2, Yuan J1, Liu Y1, Lei M1, Luo J1, Wan SP1, Zeng G1.(PubMed)
(1) Can ureteral stones cause pain without causing hydronephrosis? bySong Y1, Hernandez N2, Gee MS3, Noble VE4, Eisner BH5.(PubMed)
(2) Effects of green tea on urinary stone formation: an in vivo and in vitro study by Jeong BC1, Kim BS, Kim JI, Kim HH.(PubMed)
(3) Preventive effects of green tea on renal stone formation and the role of oxidative stress in nephrolithiasis by Itoh Y1, Yasui T, Okada A, Tozawa K, Hayashi Y, Kohri K.(PubMed)
(4) EGCG decreases binding of calcium oxalate monohydrate crystals onto renal tubular cells via decreased surface expression of alpha-enolase by Kanlaya R1,2, Singhto N1,2, Thongboonkerd V3,4.(PubMed)
(5) Gallotannin suppresses calcium oxalate crystal binding and oxalate-induced oxidative stress in renal epithelial cells by Lee HJ1, Jeong SJ, Park MN, Linnes M, Han HJ, Kim JH, Lieske JC, Kim SH.(PubMed)
(6) 1,2,3,4,6-Penta-O-galloyl-beta-D-glucose reduces renal crystallization and oxidative stress in a hyperoxaluric rat model by Lee HJ1, Jeong SJ, Lee HJ, Lee EO, Bae H, Lieske JC, Kim SH.(PubMed)
(7) Calcium oxalate stone disease: role of lipid peroxidation and antioxidants by Selvam R1.(PubMed)
(8) Vitamin E therapy prevents hyperoxaluria-induced calcium oxalate crystal deposition in the kidney by improving renal tissue antioxidant status by Thamilselvan S1, Menon M.(PubMed)