Garlic - The Whole Food Medicine for Reduced Risk and Treatment of Hyperlipidemia

Garlic (Allium sativum) is a species in the onion genus, belonging to family Amaryllidaceae, native to central Asia. It has been used popularly in traditional and Chinese medicine in treating common cold and flu to the Plague, blood pressure cholesterol levels, natural antibiotics, etc.

In a total of forty 10-month-old, male Wistar rats received intraperitoneal (IP) injection of CsA (25 mg/kg) for 28 days, the group received garlic (tablets, 400 mg/d) demonstrated reduced LDL levels compared with controls.

Also in patients with Nephrotic syndrome (NS), characterized by proteinuria, oxidative stress and endogenous hyperlipidemia, 2% garlic diet treatment diminished significantly total-cholesterol, LDL-cholesterol and triglycerides, but not HDL-cholesterol, through the attenuation of the rise of lipoperoxidation.

Dr. Bragg DA and Dr. Walling A said," The evidence to support the use of integrative medicine is limited (to the treatment of metabolic syndrome), but the strongest evidence of benefit is for garlic (Allium sativum)".

Furthermore, the Wistar male rats randomly divided into 4 diet groups with garlic supplementation study, also support the effect of garlic in the treatment of hyperlipidemia, as group treated with 200 mg raw garlic/kg body weight, demonstrated the protective effects on HDL in rats with high LDL intake.

In fact, patients with high blood cholesterol may want to add a portion of garlic into their daily diet
but patients with the presence of ulcers should only take garlic or garlic supplement with the permission of herbalists.



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Sources
(1) The effect of garlic on cyclosporine-A-induced hyperlipidemia in male rats by Taghizadeh Afshari A1, Shirpoor A, Dodangeh Balakhani E.(PubMed)
(2) Garlic ameliorates hyperlipidemia in chronic aminonucleoside nephrosis by Pedraza-Chaverrí J1, Medina-Campos ON, Granados-Silvestre MA, Maldonado PD, Olivares-Corichi IM, Hernández-Pando R.(PubMed)
(3) Garlic ameliorates gentamicin nephrotoxicity: relation to antioxidant enzymes by Pedraza-Chaverrí J1, Maldonado PD, Medina-Campos ON, Olivares-Corichi IM, Granados-Silvestre MA, Hernández-Pando R, Ibarra-Rubio ME.(PubMed)
(4) Metabolic Syndrome: Hyperlipidemia by Bragg DA1, Walling A1.(PubMed)