Asparagus, the Natural Whole Food in Reduced Risk and Treatment of Cognitive impairment

Asparagus is a flowering plant belongs to species the genus Asparagus, native to the western coasts of northern Spain, north to Ireland, Great Britain, and northwest Germany, northern Africa, and western Asia, used from early times as a vegetable and medicine, because of its delicate flavor and diuretic properties.

A recent study suggested that asparagus may process potential in the prevented progression of cognitive impairment into serve stage of aging dementia.

Cognitive impairment (MCI), is an early stage of aging-related degenerative diseases, involving the decline of memory, language, thinking, and judgment resulting in dementia.



Enzyme-treated Asparagus Officinalis extract(ETAS) in cognitive impairment SAMP8 mice reduced neuronal cell damage through the expression of information of DNA involved cytoprotective and anti-apoptotic functions.

Dr. Sakurai T, the lead researchers insisted, ETAS significantly attenuated this cell damage, restored hippocampus-dependent memory, and attenuated the effects on the cognitive impairment through its cytoprotective activities.


In an evaluation of effects of ethanolic extract of Asparagus racemosus (EEAR) on learning and memory f Swiss albino male rats for 21 days, group treated with the extract showed a significantly decreased levels of lipid peroxidation (TBARS) contents and acetylcholinesterase (AChE) activity in the brain tissue in comparison to disease control group.



In fact, EEAR roots may be an outstanding source for natural nootropic drug in the enhancement of memory or other cognitive functions, through ameliorated progressive degeneration of neurons in the central nervous system, inducing cognitive dysfunctions, the study also postulated,



Some researchers proposed that the effects of asparagus in attenuation of cognitive impairment may be also attributed to the rich content of folate, the vitamin deficiency found to associate with an increased risk for cognitive dysfunction.


These findings suggested that asparagus has processed potential neuroprotective effects against the progression of cognitive impairment. Depending on types of asparagus, large amounts of intake asparagus officinalis should only be prescribed by herbalists.


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Sources
(1) Folate: a key to optimizing health and reducing disease risk in the elderly by Rampersaud GC1, Kauwell GP, Bailey LB(PubMed)
(2) Enzyme-treated Asparagus officinalis extract shows neuroprotective effects and attenuates cognitive impairment in senescence-accelerated mice by Sakurai T, Ito T, Wakame K, Kitadate K, Arai T, Ogasawara J, Kizaki T, Sato S, Ishibashi Y, Fujiwara T, Akagawa K, Ishida H, Ohno H.(PubMed)
(3) Neuroprotective Activity of Asparagus racemosus Linn. Against Ethanol- Induced Cognitive Impairment and Oxidative Stress in Rats Brain: Auspicious for Controlling the Risk of Alzheimer′s Disease by Md. Sahab Uddin1†*, Md. Asaduzzaman1†, Abdullah Al Mamun1, Mohammed Ashraful Iqbal2, Ferdous Wahid3and Ram Kamol Rony4(Journal of Alzheimers Disease & Parkinsonism)