Beet may be a potential functional food for reduced risk and treatment of pharynx cancer, a recent study suggested
Pharynx cancer in a medical condition of abnormal cell growth in the pharynx region, including nasopharynx, hypopharynx, pharyngeal areas. In the late stage, the cancerous cells may travel a distance away to infect other healthy tissues.
Beet, best known as the beetroot or garden beet is a perennial plant with leafy stems growing to 1–2 m tall, belonging to the amaranth family.
According to the joint study lead by Vels University, the Phyto-synthetic method of producing silver nanoparticles (Ag-NPs) may be used as a mediator of beetroot in enhanced treatment of patients with pharynx cancer.
In the pharynx cancer cell line, the silver nanoparticles enhanced by the beetroot effect through induction of cytotoxicity to cause cell death, without harming the nearby healthy cells.
Silver nanoparticles used to enhanced the function of biological treatment alone or combined with other pharmaceutical substances.
Measured by MTT assay, the inhibition efficacy may depend on the higher concentration proportionally of the photosynthetic substance.
AO/EtBr staining observations also found that Ag-NPs exhibited mechanism of cell death probably through the depolarization of mitochondrial membrane potential caused by depletion of energy in induced cell proliferation, subsequently, in cell apoptosis.
In fact, according to the World Cancer Research Foundation report, strong evidence suggested that vegetables with high nitrate-containing such as beet may have a potential therapeutic effect in reduced risk and treatment of various cancers, including cancer of the pharynx.
Unfortunately, beet juice with a high amount of nitrate may associate with gastric cancer risk according to the review of literature of a total of 22 articles consisting of 49 studies—19 studies for nitrates, 19 studies for nitrites, and 11 studies for N-nitrosodimethylamine (NDMA).
Further analysis, discovered that high nitrates intake was associated with a weak but statistically significant reduced risk of gastric cancer, and increased consumption of nitrites and N-nitrosodimethylamine, NDMA may elevate the risk factors for gastric cancer.
But after taking account of other confounders, the risk of gastric cancer is not attributed to the intake of nitrate but nitrate beverage with N-nitrosodimethylamine (NDMA) contamination.
Taken together, beet and beet juice with a high concentration of nitrate may be used as a functional food to ameliorate the risk and treatment of pharynx cancer, but people with stomach ailment should avoid drinking any nitrate beverage with N-nitrosodimethylamine (NDMA) contamination.
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Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) The impact of anticancer activity upon Beta vulgaris extract mediated biosynthesized silver nanoparticles (ag-NPs) against human breast (MCF-7), lung (A549) and pharynx (Hep-2) cancercell lines by Venugopal K1, Ahmad H2, Manikandan E3, Thanigai Arul K4, Kavitha K5, Moodley MK6, Rajagopal K7, Balabhaskar R8, Bhaskar M9.(PubMed)
(2) Dietary Nitrates, Nitrites, and Nitrosamines Intake and the Risk of Gastric Cancer: A Meta-Analysis by Peng Song,1,† Lei Wu,2,† and Wenxian Guan1(PMC)
(3) It is rocket science - why dietary nitrate is hard to 'beet'! Part II: further mechanisms and therapeutic potential of the nitrate-nitrite-NO pathway by Mills CE1, Khatri J2, Maskell P2, Odongerel C2, Webb AJ2.(PubMed)
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