Intake of beet juice may have a reduced effect of inflammation through suppressing the production of pro-inflammatory cytokines produced by immunity.
Inflammation is the reaction of the immune system in protecting our body against foreign invasion causes of infection or tissue damage.
Beet, best known as the beetroot or garden beet is a perennial plant with leafy stems growing to 1–2 m tall, belonging to the amaranth family,
Intake of raw beet juice (RBJ) and cooked beet (CB) on BP of hypertensive subjects, showed a significant improvement of inflammation through regulating the cell signal protein in initiation of systemic inflammation involved in acute phase of inflammatory cytokine tumor necrosis factor-alpha (TNF-α) and reducing high-sensitivity level of C-reactive protein (hs-CRP) which have a major effect in the onset of cardiovascular risk in both tested groups.
Although the reduced blood pressure is not sustainable in tested subjects after creasing intake of raw beet juice (RBJ) and cooked beet (CB), the improvement of endothelial function as a result of the presence of nitric oxide and systemic inflammation during the test is remarkable.
Endothelial dysfunction is a major risk factor of cardiovascular disease and precedes the development of atherosclerosis.
In muscle damage following a marathon of 30 recreationally active males, using a double-blind, independent group design with doses of beetroot juice (H-BT; 250 ml), a lower dose of beetroot juice (L-BT; 125 ml), or an isocaloric placebo (PLA; 250 ml) immediately (×3 servings), oral administered beet juice groups, showed a faster recovery of muscle damage at 48 hours in compared control.
Further analysis, application of beetroot juice in any dose enhanced overexpression of antioxidants induced recover of muscle damage not only was attributed to the juice function in reduced high-sensitivity level of C-reactive protein (hs-CRP) but also increased modulation of enzyme creatine kinase (CK) responsible in expression by various tissues and cell types during muscle damage.
The antioxidant effects of beet juice also displayed a significant activity in reduced gene interleukin-6 (IL-6) secreted by T cells and macrophages in the production of pro-inflammatory cytokine to induce the acute phase of inflammation caused by muscle damage and exhibited anti-inflammatory cytokines in fighting against infection.
Additionally, administration of beetroot juice inhibited the release of neutrophils and regulated gene interleukin-8 (IL-8), a chemoattractant cytokine produced by a variety of tissue and blood cells in the expression of inflammation in the site of damage.
A neutrophil is a type of immune cells released to the site of infection by immunity. Overexpression of neutrophils normally is an indication of acute infection.
Taking all together, beet juice and products may have a remarkable effect in reduced risk of over inflammatory expression of the immune system coming to muscle damage and infection caused by microorganisms.
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Author biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Improvement of hypertension, endothelial function and systemic inflammation following short-term supplementation with red beet (Beta vulgaris L.) juice: a randomized crossover pilot study by Asgary S1, Afshani MR2, Sahebkar A3,4, Keshvari M1, Taheri M5, Jahanian E6, Rafieian-Kopaei M7, Malekian F8, Sarrafzadegan N1.(PubMed)
(2) The effects of beetroot juice supplementation on indices of muscle damage following eccentric exercise by Clifford T1, Bell O2, West DJ2, Howatson G2,3, Stevenson EJ2.(PubMed)
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