Beet or beetroot may be considered as a functional food for reduced risk of early-onset and treatment of Parkinson's disease(PD), a recent study suggested.
Parkinson's disease (PD) is a condition of neurodegenerative disease that progressed over time caused by dysfunction of nerve cells involving motor functioning, including signs of tremor of the hands, arms, legs, jaw, and face. bradykinesia ......
Beet, best known as the beetroot or garden beet and belonging to the amaranth family, is a perennial plant with leafy stems growing to 1–2 m tall.
According to the MVP Samaj's College of Pharmacy, in the animal model of PD induced by administration of reserpine (5 mg/kg/day, i.p for 5 consecutive days), haloperidol (1 mg/kg, i.p.), and tacrine (2.5 mg/kg, i.p.), rats fed with methanolic extract of Beta vulgaris (MEBV)at doses of 100, 200, and 300 mg/kg showed a significantly reduced the intensity of muscular rigidity, duration of catalepsy, akinesia, the number of tremors, dis-proportionally.
Concentrations of 200, and 300 mg/kg extract exhibited the most effects in compared dose of 100mg/kg.
Furthermore, at the higher doses, treatment animals also exerted an improvement of locomotor functioning and grip strength analyzed by MEBV.
The study also indicated that the efficacy of beet methanolic extract may be attributed to the increase of antioxidants in inhibited the production of lipid peroxidation (LPO), an important process in causing cell dysfunction in PD patients.
Not only that, but injection of the extract also restored the defensive antioxidant enzymes SOD and CAT in the rat brain.
Dr. The lead author said, "The mechanism of protection may be due to augmentation of cellular antioxidants".
Other researchers also suggested that intake of beet juice may improve the blood circulation of the brain's white matter of the frontal lobes associated with the development of dementia and other cognitive conditions, including the risk of PD and PD progression in the older adults.
Dr. Gary Miller,, the lead author of this study said, "I think these results are consistent and encouraging - that good diet consisting of a lot of fruits and vegetables can contribute to overall good health".
Collectively, the evidence suggested that beet methanolic extract or nitrate-rich beet juice may have a profound effect in the reduced prevalence of early-onset and progression of Parkinson's disease (PD) and may be considered as a functional food. for these purposes.
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Sources
(1) Neuroprotective potential of Beta vulgaris L. in Parkinson's disease by Nade VS1, Kawale LA1, Zambre SS1, Kapure AB1.(PubMed)
(2) Daily Dose Of Beet Juice Promotes Brain Health In Older Adults
Published Thursday 4 November 2010 By Janet Eppin(Medical news today)
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