Get Pregnant Naturally
".....Utilizing Traditional Chinese Medicine in Tonifying Energy flow to the Reproductive System Channels In Men and Women for Natural Conception, including Couple Who were diagnosed with Unexplained causes of Infertility...." Chantel M.
Sunday, September 25, 2022
Tomatoes Kill Bacterial Staphylococcus Aureus Against the Onset of Pneumonia
Pneumonia is a medical condition associated with the infection of the lung. In adults, the most common cause of pneumonia is bacterial infections such as Staphylococcus aureus.
Viruses or fungi also have been found to induce the onset of the disease.
The most common symptoms of pneumonia are persistent coughing with phlegm (mucus) fever, sweating, chills, and chest pain. However, depending on the types of pathogens that cause the infection.
In severe cases, pneumonia is life-threatening. Some patients at this stage also experience persistent shortness of breath due to severe inflammation in the air sacs of the lungs.
According to epidemiological studies, most cases of pneumonia are acquired from either hospitals or communities caused by people who have the disease.
Some researchers suggested people who have weakened such as elderly or immature immune systems such as babies and underage children are more prone to the disease.
Dr. Sanjay Sethi at the University at Buffalo SUNY wrote, "Pneumonia is an infection of the lungs. Pneumonia in people whose immune system is weakened or impaired (for example, by AIDS, cancer, organ transplantation, or the use of certain drugs) is often caused by different organisms than those that cause pneumonia in healthy people".
In other words, people who are treated with chemotherapy drugs due to cancer or immune suppressants, and diseases associated with immunity are susceptible to pneumonia developing.
Most cases of pneumonia are treated with antibiotics. Depending on the condition, treatment may include medicine for reduced coughing, pain, and fever with an aim to improve the patient's quality of life.
If you are taking certain types of antibiotics for the treatment of pneumonia, please make sure you know all the side effects for preventive measures.
Tomato is red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
On finding a potential ingredient for the treatment of Staphylococcus aureus pneumonia, researchers examined the effect of naringenin found abundantly in tomatoes.
In the Staphylococcus aureus pneumonia model, naringenin protected the lung cells' integrity and viability by inhibiting the production of α-toxin.
Where α-toxin is an essential virulence factor found in patients with Staphylococcus aureus pneumonia.
Furthermore, at 16 μg/ml of naringenin, treatment organisms showed reduced expression of α-toxin significantly compared to the untreated group.
Moreover, in vivo, a mouse model of S. aureus pneumonia treated with naringenin demonstrated a significant effect in attenuating symptoms of lung injury and inflammation against infection.
In other words, naringenin acted as a natural antibiotic in preventing the overexpression of α-toxin produced by Staphylococcus aureus through its antibacterial activity.
Based on the findings, Dr. Zhang Y, the lead scientist after taking into account co and confounders wrote in the final report, "These results suggest that naringenin is a promising agent for the treatment of S. aureus infection".
Taken altogether, tomatoes may be considered supplements for the prevention and treatment of Staphylococcus aureus pneumonia, pending the confirmation of the larger sample size and multicenter human study.
Intake of naringenin in the form of a supplement should be taken with extreme care to prevent overdose and acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Inhibition of α-toxin production by subinhibitory concentrations of naringenin controls Staphylococcus aureus pneumonia by Zhang Y1, Wang JF, Dong J, Wei JY, Wang YN, Dai XH, Wang X, Luo MJ, Tan W, Deng XM, Niu XD. (PubMed)
(2) Pneumonia in Immunocompromised People By Sanjay Sethi , MD, University at Buffalo SUNY. (MSD Manual)
Friday, September 16, 2022
Chronic Pain in Autosomal recessive polycystic kidney disease The Smoothie of Cherries, Ginger and Peppermint for Prevention and Treatment of chronic pain in Autosomal recessive polycystic kidney disease
Kyle J. Norton
The finding of a natural source for the treatment of Autosomal recessive polycystic kidney disease has been running into many obstacles, many ingredients shown initially with promising results in animal studies have not produced the same potential in large sample sizes and multi centers human trials.
Autosomal recessive polycystic kidney disease is an inherited disease (Mutations in the PKHD1)causing abnormal functions of the liver and reno-inducing morbidity and mortality in children.Until today, there is no cure, or treatment options for autosomal recessive polycystic kidney disease, depending on complications, such as chronic pain.
The smoothie for people with chronic pain in Autosomal recessive polycystic kidney disease
Yield: 2 servings (about 8 ounces each)
1 1/2 cups cherries cups pineapple
1 slice of ginger root
1 cup of peppermint herbal tea
1. Place all ingredients in a blender and puree for about 1 minute
2. Blend on high speed for about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drinks if needed
3. Serve immediately
Cherries(1), ginger(4), and peppermint(7) may be the next combination of therapeutic ingredients as a pain reliever for the treatment of chronic pain in patients with autosomal recessive polycystic kidney disease.
Cherry, a fleshy drupe, is the fruit of many plants of the genus Prunus cultivated all over the world for commercial profit due to its health potential.
In a randomized double-blind crossover study of 58 non-diabetic patients, oral administration of cherry juice improved the Western Ontario McMaster Osteoarthritis Index (WOMAC) scores, inducing symptom relief, including pain for patients with mild to moderate knee Osteoarthritis, through lowering the C-reactive protein CRP levels(1). According to the Oregon Health & Science University, the study of fifty-four healthy runners with ingesting 355 mL bottles of tart cherry juice twice daily for 7 days, during a strenuous running event can minimize post-run muscle pain(3).
Dr. Kuehl KS said, "Tart cherries appear to possess similar effectiveness in treating the inflammatory reaction seen in both acute and chronic pain syndromes encountered among athletes and non-athletes with chronic inflammatory disease")2) of that may be used as an antioxidant and anti-inflammatory ingredient on prevention, treatment, and recovery of soft tissue injury and pain.
Ginger (Zingiber officinale) or ginger root is the genus Zingiber, belongings to the family Zingiberaceae, native to Tamil, used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
In primary dysmenorrhea patients, ginger is effective in pain relief without inducing adverse effects and may be used as an alternative treatment for primary dysmenorrhea, according to the Mazandaran University of Medical Sciences(4) and treatment of ginger in students with primary dysmenorrhea for 5 days also showed a statistically significant effect on relieving intensity and duration of pain, the Shahid University, the study suggested(5).
Furthermore, in osteoarthritic patients, Dr. Therkleson T said," ginger therapy activated a marked relief of osteoarthritis symptoms that progressively improved over the 24 weeks, with no negative effects reported. Ginger therapy needs to be considered by nurses caring for specific personality types with osteoarthritis"(6).
Peppermint is a hybrid mint with small purple or white flowers and downy leaves, in the genus Mentha, belonging to the family Lamiaceae, native to Europe. The herb has been used in folk medicine as an analgesic, antiseptic, antispasmodic, decongestant, and agent and to relieve gas, nausea, and stomach pain due to irritable bowel, intestinal cramps, indigestion, infection, etc
According to the Translational Research Center for Gastrointestinal Disorders (TARGID), peppermint oil, with antispasmodics may be considered the first-line treatment for abdominal pain in patients with irritable bowel syndrome (IBS)(7).
Menthol, the cooling natural product of peppermint, according to the study conducted by Yale University School of Medicine, is widely used for the relief of acute and inflammatory pain in sports injuries, arthritis, and other painful conditions, through activating the methol-induced sensation of cooling(8).
Dr. Shen YH and Dr. Nahas R. said," Peppermint oil alleviates IBS symptoms, including abdominal pain" and "several complementary and alternative therapies can be recommended as part of an evidence-based approach to the treatment of IBS; these might provide patients with satisfactory relief and improve the therapeutic alliance"(9).
In the 76-year-old woman whose pain had been resistant to standard therapies, application of neat peppermint oil showed to immediately improve her pain with persistence for 4-6 hours after application of the oil(10).
Taking all together, People with Chronic Pain due to autosomal recessive polycystic kidney disease should drink the smoothie as much as they can, depending on digestive and liver toleration.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Kyle J. Norton, all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio science, ISSN 0975-6299.
References
(1) Randomized double-blind crossover study of the efficacy of a tart cherry juice blend in treatment of osteoarthritis (OA) of the knee by Schumacher HR1, Pullman-Mooar S, Gupta SR, Dinnella JE, Kim R, McHugh MP.(PubMed)
(2) Cherry juice targets antioxidant potential and pain relief by Kuehl KS1.(PubMed)
(3) Efficacy of tart cherry juice in reducing muscle pain during running: a randomized controlled trial by Kuehl KS1, Perrier ET, Elliot DL, Chesnutt JC.(PubMed)
(4) The effect of mefenamic acid and ginger on pain relief in primary dysmenorrhea: a randomized clinical trial by Shirvani MA1, Motahari-Tabari N, Alipour A.(PubMed)
(5) Effect of Zingiber officinale R. rhizomes (ginger) on pain relief in primary dysmenorrhea: a placebo randomized trial by Rahnama P1, Montazeri A, Huseini HF, Kianbakht S, Naseri M.(PubMed)
(6) Ginger Therapy for Osteoarthritis: A Typical Case by Therkleson T1.(PubMed)
(7) Treatment of abdominal pain in irritable bowel syndrome by Vanuytsel T1, Tack JF, Boeckxstaens GE.(PubMed)
(8) TRPM8 is the principal mediator of menthol-induced analgesia of acute and inflammatory pain by Liu B1, Fan L, Balakrishna S, Sui A, Morris JB, Jordt SE.(PubMed)
(9) Complementary and alternative medicine for treatment of irritable bowel syndrome by Shen YH1, Nahas R.(PubMed)
(10) A novel treatment of postherpetic neuralgia using peppermint oil by Davies SJ1, Harding LM, Baranowski AP.(PubMed)
Sunday, September 11, 2022
Phytochemical Carotenoids Block the Onset of Colorectal Cancer in Patients with DICER1 rs3742330 Genotypeancer
Cancer is a class of diseases associated with irregular cell growth in the tissue of organs.
The colon-rectum formed as a part of the digestive system is involved in the absorption of water from the small bowel contents and breaking down of certain materials in the feces into substances which of them to be reabsorbed and reused by the body.
Colorectal cancer is cancer located in the colon or rectum caused by the alternation of cell DNA. Most cases of colorectal cancer begin in the cells on the surface of inner ling tissue in either the colon or rectum, before multiplying to form a tumor.
Colorectal cancer is relatively very common and slowly growing and progressing cancer.
The disease is also the third most commonly diagnosed cancer in developed countries, including the US and Canada.
According to the statistics provided by the American Cancer Society, in the US,
101,420 new cases of colon cancer and 44,180 new cases of rectal cancer will be diagnosed in 2019.
Additionally, colorectal cancer will also cause the death of 51,020 Americans in 2019.
Overall, the lifetime risk of colorectal cancer developing is 1 in 22 (4.49%) in men and 1 in 24 (4.15%) in women.
Besides adenocarcinomas, the common type of colorectal cancer originated in epithelium tissues and squamous cells that make up the bowel lining together with the gland cells, other types of colorectal tumors include* Carcinoid
Carcinoid is an unusual type of slow-growth neuroendocrine tumor in the hormone-producing tissue in the digestive system. the condition may look benign but can spread to other parts of the body as they grow
* Leiomyosarcomas
Leiomyosarcomas are a rare and resistant type of colorectal cancer and are generally not very responsive to chemotherapy or radiation. They are a malignant abnormal mass of tissue of smooth muscles of the colon, comprising between 5–10% of soft tissue sarcomas.
* Lymphomas
Bowel lymphomas are rare and more likely to start in the rectum rather in the colon. Many patients with lymphomas are diagnosed in the late stage and already spread to other organs.
* Melanomas
Melanomas are rare malignant tumors of cells that produce dark pigment. This type of bowel cancer usually originates from somewhere else and then spread to the bowel.
Carotenoids is a class of mainly yellow, orange, or red fat-soluble pigments, including lycopene and carotene, found abundantly in ripe tomato, pumpkins, carrots, corn, and daffodils.
On finding a potential compound for the treatment of colorectal cancer, researchers investigated whether dietary lutein/zeaxanthin, the major compounds found in carotenoid intake affect colorectal cancer risk in patients with a DICER1 rs3742330 polymorphism.
The experiment included 923 colorectal cancer patients and 1,846 controls based on eligibility criteria, that answered the semiquantitative food frequency questionnaire and the DICER1 rs3742330 genotype.
Based on the returned questionnaires differentiation, the highest quartile of lutein/zeaxanthin consumption was inversely associated with colorectal cancer risk.
In genotype analysis, patients who carry the G allele (AG + GG) showed a significantly reduced colorectal cancer incidence compared to that AA carriers.
Furthermore, patients with G allele (AG + GG) along with high lutein/zeaxanthin consumption were markedly associated with a decreased colorectal cancer risk, particularly in rectal cancer compared to that AA carrier with low lutein/zeaxanthin intakes.
The results strongly suggested that carotenoids' major compounds lutein/zeaxanthin has a strong implication on the colorectal cancer risk in patients with the DICER1 rs3742330 genotype.
Dr. Kim J, the lead scientist after taking into account co and confounders wrote in the final report, " colorectal cancer risk was related to an interactive effect between dietary lutein/zeaxanthin intake and the DICER1 rs3742330 polymorphism".
Taken altogether, carotenoids may be considered a remedy for the prevention and treatment of colorectal cancer, pending the confirmation of the larger sample size and multicenter human study.
Intake of carotenoids in the form of supplements should be taken with extreme care to prevent overdose and acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional's Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Plasma and dietary carotenoids and vitamins A, C and E and risk of colon and rectal cancer in the European Prospective Investigation into Cancer and Nutrition by Leenders M1, Leufkens AM, Siersema PD, van Duijnhoven FJ, Vrieling A, Hulshof PJ, van Gils CH, Overvad K, Roswall N, Kyrø C, Boutron-Ruault MC, Fagerhazzi G, Cadeau C, Kühn T, Johnson T, Boeing H, Aleksandrova K, Trichopoulou A, Klinaki E, Androulidaki A, Palli D, Grioni S, Sacerdote C, Tumino R, Panico S, Bakker MF, Skeie G, Weiderpass E, Jakszyn P, Barricarte A, María Huerta J, Molina-Montes E, Argüelles M, Johansson I, Ljuslinder I, Key TJ, Bradbury KE, Khaw KT, Wareham NJ, Ferrari P, Duarte-Salles T, Jenab M, Gunter MJ, Vergnaud AC, Wark PA, Bueno-de-Mesquita HB. (PubMed)
(2) Antiproliferative effects of carotenoids extracted from Chlorella ellipsoidea and Chlorella vulgaris on human colon cancer cells by Cha KH1, Koo SY, Lee DU. (PubMed)
Rectal cancer
(1) (1) Plasma and dietary carotenoids and vitamins A, C and E and risk of colon and rectal cancer in the European Prospective Investigation into Cancer and Nutrition by Leenders M1, Leufkens AM, Siersema PD, van Duijnhoven FJ, Vrieling A, Hulshof PJ, van Gils CH, Overvad K, Roswall N, Kyrø C, Boutron-Ruault MC, Fagerhazzi G, Cadeau C, Kühn T, Johnson T, Boeing H, Aleksandrova K, Trichopoulou A, Klinaki E, Androulidaki A, Palli D, Grioni S, Sacerdote C, Tumino R, Panico S, Bakker MF, Skeie G, Weiderpass E, Jakszyn P, Barricarte A, María Huerta J, Molina-Montes E, Argüelles M, Johansson I, Ljuslinder I, Key TJ, Bradbury KE, Khaw KT, Wareham NJ, Ferrari P, Duarte-Salles T, Jenab M, Gunter MJ, Vergnaud AC, Wark PA, Bueno-de-Mesquita HB. (PubMed)
(2) Dietary Lutein Plus Zeaxanthin Intake and DICER1 rs3742330 A > G Polymorphism Relative to Colorectal Cancer Risk by Kim J1, Lee J1, Oh JH2, Chang HJ2, Sohn DK2, Kwon O3, Shin A4, Kim J. (PubMed)
(3) Bowel (Colorectal ) Cancer by Kyle J. Norton
The colon-rectum formed as a part of the digestive system is involved in the absorption of water from the small bowel contents and breaking down of certain materials in the feces into substances which of them to be reabsorbed and reused by the body.
Colorectal cancer is cancer located in the colon or rectum caused by the alternation of cell DNA. Most cases of colorectal cancer begin in the cells on the surface of inner ling tissue in either the colon or rectum, before multiplying to form a tumor.
Colorectal cancer is relatively very common and slowly growing and progressing cancer.
The disease is also the third most commonly diagnosed cancer in developed countries, including the US and Canada.
According to the statistics provided by the American Cancer Society, in the US,
101,420 new cases of colon cancer and 44,180 new cases of rectal cancer will be diagnosed in 2019.
Additionally, colorectal cancer will also cause the death of 51,020 Americans in 2019.
Overall, the lifetime risk of colorectal cancer developing is 1 in 22 (4.49%) in men and 1 in 24 (4.15%) in women.
Besides adenocarcinomas, the common type of colorectal cancer originated in epithelium tissues and squamous cells that make up the bowel lining together with the gland cells, other types of colorectal tumors include* Carcinoid
Carcinoid is an unusual type of slow-growth neuroendocrine tumor in the hormone-producing tissue in the digestive system. the condition may look benign but can spread to other parts of the body as they grow
* Leiomyosarcomas
Leiomyosarcomas are a rare and resistant type of colorectal cancer and are generally not very responsive to chemotherapy or radiation. They are a malignant abnormal mass of tissue of smooth muscles of the colon, comprising between 5–10% of soft tissue sarcomas.
* Lymphomas
Bowel lymphomas are rare and more likely to start in the rectum rather in the colon. Many patients with lymphomas are diagnosed in the late stage and already spread to other organs.
* Melanomas
Melanomas are rare malignant tumors of cells that produce dark pigment. This type of bowel cancer usually originates from somewhere else and then spread to the bowel.
Carotenoids is a class of mainly yellow, orange, or red fat-soluble pigments, including lycopene and carotene, found abundantly in ripe tomato, pumpkins, carrots, corn, and daffodils.
On finding a potential compound for the treatment of colorectal cancer, researchers investigated whether dietary lutein/zeaxanthin, the major compounds found in carotenoid intake affect colorectal cancer risk in patients with a DICER1 rs3742330 polymorphism.
The experiment included 923 colorectal cancer patients and 1,846 controls based on eligibility criteria, that answered the semiquantitative food frequency questionnaire and the DICER1 rs3742330 genotype.
Based on the returned questionnaires differentiation, the highest quartile of lutein/zeaxanthin consumption was inversely associated with colorectal cancer risk.
In genotype analysis, patients who carry the G allele (AG + GG) showed a significantly reduced colorectal cancer incidence compared to that AA carriers.
Furthermore, patients with G allele (AG + GG) along with high lutein/zeaxanthin consumption were markedly associated with a decreased colorectal cancer risk, particularly in rectal cancer compared to that AA carrier with low lutein/zeaxanthin intakes.
The results strongly suggested that carotenoids' major compounds lutein/zeaxanthin has a strong implication on the colorectal cancer risk in patients with the DICER1 rs3742330 genotype.
Dr. Kim J, the lead scientist after taking into account co and confounders wrote in the final report, " colorectal cancer risk was related to an interactive effect between dietary lutein/zeaxanthin intake and the DICER1 rs3742330 polymorphism".
Taken altogether, carotenoids may be considered a remedy for the prevention and treatment of colorectal cancer, pending the confirmation of the larger sample size and multicenter human study.
Intake of carotenoids in the form of supplements should be taken with extreme care to prevent overdose and acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional's Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Plasma and dietary carotenoids and vitamins A, C and E and risk of colon and rectal cancer in the European Prospective Investigation into Cancer and Nutrition by Leenders M1, Leufkens AM, Siersema PD, van Duijnhoven FJ, Vrieling A, Hulshof PJ, van Gils CH, Overvad K, Roswall N, Kyrø C, Boutron-Ruault MC, Fagerhazzi G, Cadeau C, Kühn T, Johnson T, Boeing H, Aleksandrova K, Trichopoulou A, Klinaki E, Androulidaki A, Palli D, Grioni S, Sacerdote C, Tumino R, Panico S, Bakker MF, Skeie G, Weiderpass E, Jakszyn P, Barricarte A, María Huerta J, Molina-Montes E, Argüelles M, Johansson I, Ljuslinder I, Key TJ, Bradbury KE, Khaw KT, Wareham NJ, Ferrari P, Duarte-Salles T, Jenab M, Gunter MJ, Vergnaud AC, Wark PA, Bueno-de-Mesquita HB. (PubMed)
(2) Antiproliferative effects of carotenoids extracted from Chlorella ellipsoidea and Chlorella vulgaris on human colon cancer cells by Cha KH1, Koo SY, Lee DU. (PubMed)
Rectal cancer
(1) (1) Plasma and dietary carotenoids and vitamins A, C and E and risk of colon and rectal cancer in the European Prospective Investigation into Cancer and Nutrition by Leenders M1, Leufkens AM, Siersema PD, van Duijnhoven FJ, Vrieling A, Hulshof PJ, van Gils CH, Overvad K, Roswall N, Kyrø C, Boutron-Ruault MC, Fagerhazzi G, Cadeau C, Kühn T, Johnson T, Boeing H, Aleksandrova K, Trichopoulou A, Klinaki E, Androulidaki A, Palli D, Grioni S, Sacerdote C, Tumino R, Panico S, Bakker MF, Skeie G, Weiderpass E, Jakszyn P, Barricarte A, María Huerta J, Molina-Montes E, Argüelles M, Johansson I, Ljuslinder I, Key TJ, Bradbury KE, Khaw KT, Wareham NJ, Ferrari P, Duarte-Salles T, Jenab M, Gunter MJ, Vergnaud AC, Wark PA, Bueno-de-Mesquita HB. (PubMed)
(2) Dietary Lutein Plus Zeaxanthin Intake and DICER1 rs3742330 A > G Polymorphism Relative to Colorectal Cancer Risk by Kim J1, Lee J1, Oh JH2, Chang HJ2, Sohn DK2, Kwon O3, Shin A4, Kim J. (PubMed)
(3) Bowel (Colorectal ) Cancer by Kyle J. Norton
Sunday, September 4, 2022
#Healthyfood #Tomato, the Natural and Potential Anti-Inflammatory Remedy, Researchers Say
Inflammation is a natural response by the immune system to protect the body against the invasion of stimuli or foreign pathogens.
In other words, the white blood cells on the first line of defense of the immune system after sensing the danger of an infection in the body through a message from the brain stimulate the production of the palette to cover the site of injury or damage and inflammatory cytokines to kill off all pathogens before they can cause harm to the body.
Most cases of infection are stopped at the acute phase. The wound or injury is slowly recovered.
However, in severe cases, particularly in people with a weakened immune system, the inflammatory progression cannot be stopped due to the inability of the immune system to destroy all invaders, leading to low-grade chronic inflammation.
Diseases associated with low-grade inflammation include diabetes and cardiovascular.
Believe it or not, worldwide, 3 of 5 death are results from chronic inflammatory diseases like stroke, chronic respiratory diseases, heart disorders, cancer, obesity, and diabetes.
In the US, chronic inflammatory diseases affect more than 50 million Americans each year.
Dr. Roma Pahwa in the classification of chronic inflammation wrote, "Chronic inflammation is also referred to as slow, long-term inflammation lasting for prolonged periods of several months to years. Generally, the extent and effects of chronic inflammation vary with the cause of the injury and the ability of the body to repair and overcome the damage".
And, "(The causes of chronic inflammation are) Failure of eliminating the agent causing acute inflammation, ..., Exposure to a low level of a particular irritant or foreign materials,...An autoimmune disorder,... Recurrent episodes of acute inflammation,... Inflammatory and biochemical inducers"
Tomato is red, edible fruit, genus Solanum, and belongs to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
On finding a potential compound for the treatment of inflammatory diseases researchers examined the effect of tomato ketchup extracts and bioactive from tomato ketchup on human monocytes and vascular endothelial cells (HUVEC).
HUVEC selected for the study were pre-treated for 1 h with either individual bioactive (7.5 µM lycopene, 1.4 µM α-tocopherol, or 55 µM ascorbic acid) or a combination of these three compounds, or with the hydrophilic or lipophilic tomato ketchup extracts or with the two extracts combined.
According to the tested assays, tomato ketchup extracts significantly reduced gene expression and pro-inflammatory cytokines TNF-α and IL-8 in HUVEC after inducing inflammation.
Furthermore, levels of anti-inflammatory release were increased observed by the expression of anti-inflammatory cytokine IL-10.
The effects were correlated with the reduction of IL-8 production in the presence of the test compounds and extracts.
In other words, lycopene found in tomato extract is one of the major bioactive compounds that induce the anti-inflammatory effect, and α-tocopherol and ascorbic acid appeared to strengthen the anti-inflammatory effect of lycopene.
In order to obtain more information about tomato anti-inflammatory activity, researchers analyzed the potential protective effects of phytochemicals in tomatoes on inflammation.
According to the nitric oxide (NO) assay, tomato extract exhibited an anti-inflammatory effect by inhibiting the NO production in LPS-stimulated RAW264 macrophages.
Levels of pro-inflammatory cytokines were significantly decreased after the injection of tomatoes.
The efficacy of tomatoes was attributed to the bioactive compound RF52 in the inhibition of the production of these proinflammatory mediators.
Dr. Kim YI, the lead scientist said, "These results suggest that RF52 from tomatoes may have the potential to suppress inflammation by inhibiting the production of NO or proinflammatory cytokines during the interaction between adipocytes and macrophages".
Taken altogether, tomatoes may be considered functional food for the prevention and treatment of inflammatory diseases, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional's Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Protection against chemotaxis in the anti-inflammatory effect of bioactives from tomato ketchup by Hazewindus M1, Haenen GR1, Weseler AR1, Bast A. (PubMed)
(2) Tomato extract suppresses the production of proinflammatory mediators induced by interaction between adipocytes and macrophages by Kim YI1, Mohri S, Hirai S, Lin S, Goto T, Ohyane C, Sakamoto T, Takahashi H, Shibata D, Takahashi N, Kawada T. (PubMed)
(3) Chronic Inflammation by Roma Pahwa; Ishwarlal Jialal. (NCBI)
In other words, the white blood cells on the first line of defense of the immune system after sensing the danger of an infection in the body through a message from the brain stimulate the production of the palette to cover the site of injury or damage and inflammatory cytokines to kill off all pathogens before they can cause harm to the body.
Most cases of infection are stopped at the acute phase. The wound or injury is slowly recovered.
However, in severe cases, particularly in people with a weakened immune system, the inflammatory progression cannot be stopped due to the inability of the immune system to destroy all invaders, leading to low-grade chronic inflammation.
Diseases associated with low-grade inflammation include diabetes and cardiovascular.
Believe it or not, worldwide, 3 of 5 death are results from chronic inflammatory diseases like stroke, chronic respiratory diseases, heart disorders, cancer, obesity, and diabetes.
In the US, chronic inflammatory diseases affect more than 50 million Americans each year.
Dr. Roma Pahwa in the classification of chronic inflammation wrote, "Chronic inflammation is also referred to as slow, long-term inflammation lasting for prolonged periods of several months to years. Generally, the extent and effects of chronic inflammation vary with the cause of the injury and the ability of the body to repair and overcome the damage".
And, "(The causes of chronic inflammation are) Failure of eliminating the agent causing acute inflammation, ..., Exposure to a low level of a particular irritant or foreign materials,...An autoimmune disorder,... Recurrent episodes of acute inflammation,... Inflammatory and biochemical inducers"
Tomato is red, edible fruit, genus Solanum, and belongs to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
On finding a potential compound for the treatment of inflammatory diseases researchers examined the effect of tomato ketchup extracts and bioactive from tomato ketchup on human monocytes and vascular endothelial cells (HUVEC).
HUVEC selected for the study were pre-treated for 1 h with either individual bioactive (7.5 µM lycopene, 1.4 µM α-tocopherol, or 55 µM ascorbic acid) or a combination of these three compounds, or with the hydrophilic or lipophilic tomato ketchup extracts or with the two extracts combined.
According to the tested assays, tomato ketchup extracts significantly reduced gene expression and pro-inflammatory cytokines TNF-α and IL-8 in HUVEC after inducing inflammation.
Furthermore, levels of anti-inflammatory release were increased observed by the expression of anti-inflammatory cytokine IL-10.
The effects were correlated with the reduction of IL-8 production in the presence of the test compounds and extracts.
In other words, lycopene found in tomato extract is one of the major bioactive compounds that induce the anti-inflammatory effect, and α-tocopherol and ascorbic acid appeared to strengthen the anti-inflammatory effect of lycopene.
In order to obtain more information about tomato anti-inflammatory activity, researchers analyzed the potential protective effects of phytochemicals in tomatoes on inflammation.
According to the nitric oxide (NO) assay, tomato extract exhibited an anti-inflammatory effect by inhibiting the NO production in LPS-stimulated RAW264 macrophages.
Levels of pro-inflammatory cytokines were significantly decreased after the injection of tomatoes.
The efficacy of tomatoes was attributed to the bioactive compound RF52 in the inhibition of the production of these proinflammatory mediators.
Dr. Kim YI, the lead scientist said, "These results suggest that RF52 from tomatoes may have the potential to suppress inflammation by inhibiting the production of NO or proinflammatory cytokines during the interaction between adipocytes and macrophages".
Taken altogether, tomatoes may be considered functional food for the prevention and treatment of inflammatory diseases, pending the confirmation of the larger sample size and multicenter human study.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Protection against chemotaxis in the anti-inflammatory effect of bioactives from tomato ketchup by Hazewindus M1, Haenen GR1, Weseler AR1, Bast A. (PubMed)
(2) Tomato extract suppresses the production of proinflammatory mediators induced by interaction between adipocytes and macrophages by Kim YI1, Mohri S, Hirai S, Lin S, Goto T, Ohyane C, Sakamoto T, Takahashi H, Shibata D, Takahashi N, Kawada T. (PubMed)
(3) Chronic Inflammation by Roma Pahwa; Ishwarlal Jialal. (NCBI)
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