Honey inhibits the Expression of Oxidative Stress with No Side Effects

Scientists may have found a natural alternative for the treatment of diseases associated with oxidative stress, according to studies.

Oxidative stress is a medical condition associated with the overexpression of free radicals compared to low levels of antioxidant enzymes produced by the host.

In fact, free radicals are constantly produced in animal and human cells. The air we breathe, the thing we eat, and the environment we contact are some factors that cause the production of reactive oxygen species (ROS).

Epidemiological studies suggested that oxidative stress can induce damage to the cell, lipid, proteins, and alternation of cell DNA, leading to chronic diseases, such as cardiovascular diseases, diabetes, and particularly, cancer.

How overexpression of free radicals causes damage to the cells. Researchers explained due to free radical unstable nature with unpair of electrons on the out ring of molecules, they constantly seek to donate or intercept the electron from other stable atoms, leading to a chain reaction that can not be stopped until all unpaired electrons are paired or inhibited by antioxidants.

These processes can lead to an imbalance of the ratio of free radicals and antioxidants produced by the host body resulting in oxidative stress, a major cause of cell, lipid, and protein damage.

In spite of free radical's harmful effects, one must understand that cellular oxygen species (ROS), are necessary with a moderate amount to protect our body in the mediation of antimicrobial infection, detoxification of potentially toxic compounds, and elimination of cancerous and other life-threatening cells through cytotoxicity.

On the other hand, antioxidants are stable molecules that inhibit oxidation. Antioxidants can reduce levels of free radicals and overexpression can limit the free radical function in carrying out their health benefits.

Therefore, in order to maintain good health, the levels of free radicals and antioxidants must be balanced.


Honey is a miraculous product made by bees using nectar from flowers.

The rich golden liquid is considered one of the healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.

Researchers on finding a natural compound for the inhibition of oxidative stress examined the honey activity on oxidative stress induced by lead acetate exposure in male Wistar rats.

The study included 24 male Wistar rats randomly divided into four groups: Control group that received 1 ml/kg distilled orally for 28 days; while groups II-IV received 0.2% lead in drinking water and 1 ml/kg of distilled water, 1 ml/kg of honey, 1.5 ml/kg of honey respectively for 28 days.

Before pretreatment with honey, infected rats showed a decrease in locomotor and exploratory and decrease antioxidant activity increase in anxiety, memory impairment, lipid peroxidation.



Co-administration of honey with lead inhibited neurotoxicity observed by the improvement in memory function and decreased latency period and increased in time spent in target quadrant compared to the lead-exposed animals.


Injection of honey in the lead-fed group also increased locomotion, exploration, and decreased anxiety observed by the frequency of rearing, freezing duration, and the number of lines crossed by animals.

More importantly, the administration of honey improved the levels of antioxidant enzymes produced by the host observed by increased brain SOD, GST, and GSH activities compared to the lead-treated groups.


However, the honey pretreatment group showed no significant effect on MDA level, the oxidative stress marker.

These results suggested that honey exerted neuroprotective effects against lead-induced cognitive deficit probably by enhancing antioxidant activities without affecting the levels of MDA.



In order to reveal more information about honey antioxidative stress, researchers investigated the effects of Tualang honey (TH) protective activity against oxidative stress of exercise.

The study included 20 female athletes (aged 21.3 [2.1] years; body weight [BW] 54.1 [5.7] kg) were randomly assigned into two groups and consumed either 1.5 g/kg BW TH (high honey; HH; n = 10) or 0.75 g/kg BW TH (low honey; LH; n = 10).

Injection of Tualang honey showed a reduction of MDA in the LH group compared to the HH group. In other words, less oxidative stress was found in the LH group.


The concentrations of total phenolic content (TPC) and antioxidant activity (ferric reducing antioxidant power [FRAP]) increased from baseline to 2 and 1 h after TH consumption, respectively, then the concentrations returned toward baseline at 3 h in both LH and HH groups.


MDA concentration significantly decreased (p < 0.05) from baseline to 2 h and significantly increased from 2 to 3 h in the HH group. Meanwhile, ROS levels increased significantly from 0.5 to 3 h in the HH group.

Compared to the HH group, the LH group showed similar trends but insignificant increased levels of MDA and ROS.

Taken altogether, honey particularly Tualang honey may be considered functional remedies for the prevention and treatment of diseases related to the expression of oxidative stress with no side effects, pending the confirmation of a large sample size and multicenter human study



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Ovarian Cysts And PCOS Elimination
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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.

Sources:
(1) Honey prevents neurobehavioural deficit and oxidative stress induced by lead acetate exposure in male Wistar rats- a preliminary study by Abdulmajeed WI1, Sulieman HB2, Zubayr MO2, Imam A3, Amin A2, Biliaminu SA4, Oyewole LA2, Owoyele BV. (PubMed)
(2) Dose-Response Effect of Tualang Honey on Postprandial Antioxidant Activity and Oxidative Stress in Female Athletes: A Pilot Study by Ahmad NS1, Abdul Aziz A2, Kong KW2, Hamid MSA3, Cheong JPG1, Hamzah SH1. (PubMed)
(3) The benefits and hazards of antioxidants: controlling apoptosis and other protective mechanisms in cancer patients and the human population by Salganik RI. (PubMed)

Healthy Food Tomatoes Modulate Immune Function to the Body Needs, Studies Find

The immune system plays a critical role in the body's defense against infectious organisms and other pathogens.

The immune function can be classified into subsystems, including the innate and adaptive responses.

* The innate responses are the general response of the immune system that can act quickly to destroy invaders, regardless of the type of organism.


* The adaptive responses develop slowly on first exposure to a new pathogen slowly. In some cases, it may take a week or so before the responses are effective.


However, due to the quick division of bacteria, (a single bacterium with a doubling time of one hour can produce almost 20 million progeny), therefore, our body is totally dependent on the innate immune system to destroy the invader in the first critical hours and days of exposure.


Believe it or not, if the innate immune subsystem cannot destroy the foreign invader in a set period of time from 3 -8 weeks, it will compromise, leading to low-grade inflammation in facilitating the onset of various diseases, including cardiovascular disease, diabetes, and arthritis.


Immune modulation is the process to increase and decrease immune functioning depending on the needs of the body. In people with a weakened immune system, modulation of the immune system is found to enhance immune functioning against infectious agents.


However, in people with overactive immunity, modulation of the immune function will reduce the risk of the immune system attacking the body tissues.


Tomato is red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.

With an aim to find a potential compound with immune-modulatory activity, researchers examined the influence of tomato aqueous extract (TAE) on the in vitro inflammatory response.


According to the results observed by the Murine macrophages (RAW264.7 cells), PBLs and HUVECs incubated with TAE, TAE exerted a significant effect in the inhibition of pro-inflammatory cytokines such as L-1β, IL-6, IL-10, IL-12 and chemokines such as CCL2/MCP-1, CCL3/MIP-1α.

In the endothelial cell, TAE reduced ED-associated expression of adhesion molecules (ICAM-1, VCAM-1) associated with the production of inflammation.


In macrophages, the production of pro-inflammatory proteins associated with low-grade inflammation also inhibited the injection of TAE.

Based on the findings, researchers said, "during acute inflammation, TAE enhances cellular alertness and therefore the sensing of disturbed immune homeostasis in the vascular-endothelial compartment. Conversely, it blunts inflammatory mediators in macrophages during chronic inflammation".


In other words, TAE protects the integrity and viability of immune cells by modulating the immune activity depending on the needs of the body.


Furthermore, in a blinded, randomized, cross-over study, male subjects on a low-carotenoid diet consumed 330 ml/day of either tomato juice (37.0 mg/day lycopene) or carrot juice (27.1 mg/day beta-carotene and 13.1 mg/day alpha-carotene) for 2 weeks with a 2-week depletion period after juice intervention, researchers compared the effects of a low-carotenoid diet supplemented with either tomato (providing high amounts of lycopene) or carrot juice (providing high amounts of alpha- and beta-carotene) on immune functions in healthy man.


According to the results from the tested assays, juice consumption showed relatively fast responses in plasma carotenoid concentrations (p < 0.0002) without being accompanied by concomitant changes in immune functions.


However, increased plasma carotenoid concentrations after vegetable juice consumption were accompanied by a time-delayed modulation of immune functions in healthy men consuming a low-carotenoid diet.

Precisely, tomato juice modulated the immune function in a delay and concentration-dependent manner.

Taken altogether, tomatoes may be considered supplements for the modulation of immune function based on the body needs, pending the confirmation of the larger sample size and multicenter human study.



Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Tomato Aqueous Extract Modulates the Inflammatory Profile of Immune Cells and Endothelial Cells by Schwager J1, Richard N2, Mussler B3, Raederstorff D. (PubMed)
(2) Supplementation of a low-carotenoid diet with tomato or carrot juice modulates immune functions in healthy men by Watzl B1, Bub A, Briviba K, Rechkemmer G. (PubMed)

Antioxidant Omega 3 Fatty Acids Suppress Cancer Cachexia in Patients with Pancreatic Cancer

The pancreas is an oblong flattened gland in the digestive and endocrine system located in the abdomen. By secreting pancreatic juice to the small intestine, the pancreas helps to break down carbohydrates, proteins, and lipids.


Traditional Chinese medicine views the pancreas, as a vital organ that is responsible for the absorption of foods' qi and nutrients before passing them to other organs to nourish our body.

More precisely, the functions of the pancreas including
* Production of enzymes digest fat, protein, and
carbohydrates.

* production of juices combined with juices from the intestines helps to do the job of breaking down protein, carbohydrates, and fat, therefore, it plays an important role in maintaining good health.

* Production of insulin, which is important in regulating the amount of sugar or glucose in the blood.

Pancreatic cancer is a chronic condition characterized by cell growth irregularly in the tissues of the pancreas.

According to statistics, every year, approximately, 55,000 adults in the United States are diagnosed with pancreatic cancer, accounting for 3% of all cancers and 7% of all cancer deaths.

The survival rate of pancreatic cancer even diagnosed early is very low compared to other types of cancer. The 5-year survival rate at stage IA pancreatic cancer is only14%.

Researchers do not know what causes pancreatic cancer. They don't even know why people with the same health conditions in the same family, are susceptible to pancreatic cancer, while others do not.

The most common risk factors of pancreatic cancer are similar to those of common cancers, including age, family history, gender, ethnicity, smoking, being overweight or obesity, and certain medical conditions such as diabetes.

Cancer cachexia is a condition a multifactorial syndrome associated with an ongoing loss of skeletal muscle mass.


Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.


The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of cancer, researchers examined the effects of omega-3 fatty acids in patients with pancreatic and bile duct cancer.

According to the administration of Racol®, an enteral nutrient formulated with omega-3 fatty acids to patients with unresectable pancreatic and bile duct cancer at 4 and 8 weeks after, pre-administration and administration showed a strong activity that increases skeletal muscle mass at both 4 and 8 weeks.


In other words, Omega-3 fatty acid supplementation protects the skeletal muscle mass associated with cancer cachexia in patients with unresectable pancreatic cancer may improve cancer.


Taken altogether, Omega-3 fatty acids found abundantly in fish oil and plant oil may be considered a functional food for the reduction of cancer cachexia in patients with pancreatic cancer, pending the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Omega-3 Fatty Acids Prevent Early Pancreatic Carcinogenesis via Repression of the AKT Pathway by Ding Y1, Mullapudi B2, Torres C3, Mascariñas E4,5, Mancinelli G6, Diaz AM7, McKinney R8, Barron M9, Schultz M10,11, Heiferman M12, Wojtanek M13, Adrian K14, DeCant B15,16, Rao S17, Ouellette M18, Tsao MS19, Bentrem DJ20, Grippo PJ. (PubMed)
(2) Effects of ω-3 Fatty Acid Supplementation in Patients with Bile Duct or Pancreatic Cancer Undergoing Chemotherapy by Abe K1, Uwagawa T2, Haruki K2, Takano Y2, Onda S2, Sakamoto T2, Gocho T2, Yanaga K. (PubMed)

Healthy Food Honey, the Best for the Treatment of Chronic Cough with No Side Effects

Scientists may have found a natural alternative for the treatment of chronic cough, according to studies.
Cough is a natural human reflex that clears the throat of mucus or foreign irritants.

Although it is not common, coughing also is used to clear foreign substances and irritants infrequently associated with a certain lung infection.

Unlike an acute cough, chronic cough is a cough that lasts more than eight weeks. The most common causes of a chronic cough are a postnasal drip, asthma, and acid reflux.


Believe it or not, postnasal drip, asthma, and acid reflux are found in 90% of patients with a chronic cough.

According to the statistic, approximately, 2.% of US adults suffer from a chronic cough, and the risk of chronic cough of current smokers is substantially higher compared to non-smokers.

Besides smoking, people with chronic lung diseases such as asthma, bronchiectasis, COPD, and previous lung infections with scars are also at increased risk of developing a chronic cough.


Some researchers suggested that obese children may also be at risk of chronic conditions.


Dr. S Deane, the lead scientist in the assessment of the obese risk of chronic cough in children said, "Obese children have more respiratory symptoms than their normal-weight peers and respiratory-related pathology increases with increasing weight"


And, "Some will need specialist assessment (box 1). Obesity produces mechanical effects on respiratory system performance. Breathlessness, wheeze, and cough are not related to increased airway responsiveness and may respond more to weight loss than bronchodilator therapy. A significant number of obese children have signs and symptoms of obstructive sleep apnoea largely related to the effect of obesity on upper airway dimensions".


These results strongly suggested that the increased weight of obese children is the major risk factor on the development of chronic cough.


Honey is a miraculous product made by bees using nectar from flowers.

The rich golden liquid is considered one of the healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.

Scientists searching for a natural remedy for the treatment of a chronic cough without inducing adverse effects compared the effects of a single nocturnal dose of 3 honey products (eucalyptus honey, citrus honey, or Labiatae honey) to placebo (silan date extract) on nocturnal cough associated with childhood upper respiratory tract infections (URIs).


The study included 300 children aged 1 to 5 years with URIs, nocturnal cough, and illness duration of ≤ 7 days from 6 general pediatric community clinics. Eligible children received a single dose of 10 g of eucalyptus honey, citrus honey, Labiatae honey, or placebo administered 30 minutes before bedtime.

According to the results from 2 consecutive days, there was a significant improvement from the night before treatment to the night of treatment in the treatment group compared to the placebo.


Furthermore, according to the parents' review, the honey exhibited a higher than the silan date extract for symptomatic relief for their children's nocturnal cough and sleep difficulty.


In order to reveal more information about honey against a chronic cough in children, researchers examined the honey effect in the persistent post-infectious cough (PPC) that lasts more than three weeks or perhaps for many months.


The double-blind randomized controlled trial was conducted from 2008 to 2011 at the Baqiyatallah University Hospital, Tehran, Iran. included 97 adults who experienced PPC for more than three weeks randomly distributed into three groups.

Participants were given either a jam-like paste included honey plus coffee for the first group ('HC'), orprednisolone for the second group (steroid, 'S'), or guaifenesin for the third group (control, 'C').


All participants were told to dissolve a specified amount of their product in warm water and drink the solution every eight hours for one week.

The mean (+/- SD) cough scores pre- and post-treatment were: HC group 2.9 (0.3) pre-treatment and 0.2 (0.5) post-treatment (p < 0.001), and steroid ('S') group 3.0 (0.0) pre-treatment and 2.4 (0.6) post-treatment (p < 0.05)


The control ('C') group exerted mean (+/- SD) cough scores of 2.8 (0.4) pre-treatment and 2.7 (0.5) post-treatment (p > 0.05).


By Analysing the variance, researchers found that there is a significant difference between the mean cough frequency before and after treatment in the HC group, compared in the S group


Honey plus coffee was found to be the most effective modality for PPC, compared to other groups.


Taken altogether, honey may be considered an alternative remedy for the prevention and treatment of chronic coughs in children and adults, pending the confirmation of large sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.

Sources
(1) Effect of honey on nocturnal cough and sleep quality: a double-blind, randomized, placebo-controlled study by Cohen HA1, Rozen J, Kristal H, Laks Y, Berkovitch M, Uziel Y, Kozer E, Pomeranz A, Efrat H. (PubMed)
(2) Honey plus coffee versus systemic steroid in the treatment of persistent post-infectious cough: a randomised controlled trial by Raeessi MA1, Aslani J, Raeessi N, Gharaie H, Karimi Zarchi AA, Raeessi F. (PubMed)
(3) Obesity and the pulmonologist by S Deane and A Thomson. (PMC)

Healthyfood Honey, the Natural Pain Reliever with No Side Effects

Scientists may have found a natural alternative pain relief remedy for alleviating pain, according to studies. found.

Pain relief is an action to remove pain, distress, oppression by blocking the pain-transmitting information from nerve cells to the brain neurons.

Acute pain is any pain that lasts less than 6 months. Most cases of acute pain are due to physical damage such as soft tissue damage of a sprained ankle or a paper cut. Acute pain is relatively more sharp and severe.

On the other hand, there are many risk factors associated with chronic pain. Some chronic pains can be caused by single factors such as diseases involving nerve damage to injuries that fail to heal properly. Others may result from several factors including diseases associated with normal aging.


Over-the-counter medications used for the treatment of pain includes acetaminophen (Tylenol) and nonsteroidal anti-inflammatory drugs (NSAIDs).

Besides the gastrointestinal discomforts, long-term use of Tylenol may be additive. Overdoses or consumption together with alcohol, Tylenol can cause liver damage in severe cases.


If you are taking some over-the-counter medicine for pain-relieving, please make sure you know all the side effects of the preventive measure.

Honey is a miraculous product made by bees using nectar from flowers.

The rich golden liquid is considered one of the healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.

Researchers on finding a natural ingredient for pain relief examined the honey effect as adjunct pain therapy.

The pain relief of honey was the result of the contribution of the numerous phytochemicals and components, including the interaction of protein, amino acid, flavonoids, phenolics, organic acid, pigment, water, and (high) sugar content in honey.


These components work together to relieve pain by exerting antibacterial, antiinflammation, and immunomodulation properties.


According to additional differentiation, honey reduced pain through the expression of the level of the central and peripheral nervous system or at the autonomic receptor sites involved in pain transmission via the cyclooxygenase pathway in nociception and pain.

Furthermore, in the examined the honey pain relief in post-tonsillectomy treatment with or without adenoidectomy, researchers launched a randomized, double-blind, placebo-controlled study that included 140 patients, who were older than eight.

Patients were divided into two equal groups, honey, and placebo.

Compared the acetaminophen plus honey for the honey group, and acetaminophen plus placebo for the placebo group, researchers found that
* According to the visual analog scale (VAS) and a number of painkillers taken within the first three postoperative days, acetaminophen and acetaminophen plus honey groups showed a statistically significant reduction of pain.

*The reduced use of painkillers differed significantly in every five postoperative days.

* Pain awoke at night is also reduced with no difference between groups.

* Honey injection exerted negligible side effects

These results strongly showed that postoperative honey administration reduces postoperative pain and analgesic requirements in patients after tonsillectomy.


Taken all together, there is no doubt that honey may be considered a functional remedy for pain relief with few side effects, pending the confirmation of large sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.

Sources
(1) Chapter 10 - Honey—A Natural Remedy for Pain Relief by Author links open overlay panelN.M.LazimA.Baharudin. (PubMed)
(2) Post Tonsillectomy Pain: Can Honey Reduce the Analgesic Requirements? by Peyman Boroumand,1 Mohammad Mahdi Zamani,2 Masoumeh Saeedi,1Omid Rouhbakhshfar,1 Seyed Reza Hosseini Motlagh,1 and Fatemeh Aarabi Moghaddam. (PubMed)

Healthy Food Honey, the Best Remedy for Depression with No Side Effects

Scientists may have found a natural alternative for the treatment of depression according to studies.
Depression is a common and serious psychological illness, affecting the physical and mental functions of patients, including the ways patients feel, think and act.

Some patients with depression may feel sadness and/or a loss of interest in activities once enjoyed.

There are many causes associated with the onset of depression, including genetics, changes in hormone levels, certain medical conditions, stress, grief, or difficult life circumstances that initiate the change of brain chemistry in inducing depressive syndrome.

The most common symptoms of depression include sadness, hopelessness, guilt, change of mood, loss of interest in friends, family, favorite activities, and sex.

Some patients with depression also experience cognitive symptoms of trouble concentrating, making decisions, remembering, and thoughts of harming themselves.

Readers may find other symptoms not be included in the article including behavior and physical symptoms.

According to the statistics provided by the Anxiety and Depression Association of American, major depressive disorder is the leading cause of disability in the U.S. for ages 15 to 44.3, affecting more than 16.1 million American adults, or about 6.7% of the U.S. population age 18 and older.

Some researchers suggested that the widespread depression in the Western world may be associated with life stress at work and home.

Dr. T. Plieger, the lead scientist in examining the effects of psychological stress on depression wrote, "A significantly closer relation between depression and life stress than between burnout and life stress was found in the healthy (z = 3.01, p = .003) as well as in the depressed sample".

And "This finding was supported in both samples by means of a path analytic approach where the associations between life stress, burnout, and depression were controlled for the possible mediator and moderator effects, also considering the influence of age".


Honey is a miraculous product made by bees using nectar from flowers.

The rich golden liquid is considered one of the healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.

Scientists searching for an alternative remedy for the treatment of depression with no side effects examined the effects of honey on several studies through searching the database of online medical literature.

8 studies that satisfied the standard criteria and guidelines were chosen, including 2 RCTs of human subjects and 6 animal studies.

The randomized studies suggested that depressed elderly treated with a mix of honey and barely exhibited a significant decrease in depression, stress, and mood disturbances scores compared to the control group.

In menopause women, treatment with honey or a mix of honey and pollens exerted a significant activity in the improvement of the three subscales of the Menopause Rating Scale (MRS) by 68.3% and 70.9%, respectively.

The results also suggested that posttreatment demonstrates a better effect compared to the pretreatment when the mixture of honey was applied.


Furthermore, the application showed similar effects on the serum levels of cholesterol, such as total, HDL, or LDL cholesterol), triglycerides, or oestradiol in both groups.

According to the survey returned, participants reported that they observed improvements 3-4 days after the initiation of treatment. On a 10-point taste scale, (1 = very good and 10 = very bad) honey received an average score of 2.3, whereas a honey and pollen mix received an average score of 6.0.

Interestingly, the side effects of exhaustion and edema of lower extremities were reported by some participants and 2 participants were withdrawn from the study due to the taste of the mix of honey with bare powder.

In animal studies, all experiments displayed a positive effect of honey on depression. Some studies also found that honey improves depressive-like behaviors, cognitive function, and symptoms of anhedonia.

Furthermore, honey injection also showed a reduction of anxiety symptoms and improvement of spatial memory.

Moreover, honey alone or a combination of honey and other bee products inhibited MAO enzyme activity in the liver of treated mice.

Where monoamine oxidase A (MAO-A), an enzyme that metabolizes monoamines was elevated in depressed patients.

And, the anti-depressive effects were correlated to the volume of honey intake. In other words, greater improvements were associated with the increased administration of high doses of honey.

In order to reveal more information about honey depression activity, researchers examined
Tualang and Acacia honey in patients with stress-depression disorder.

Both Tualang and Acacia honey showed a significant anti-depression activity through increasing the production of levels of antioxidants.

However, Tualang honey consumption was found to be more suitable in regulating weight-related effects of stress-depression disorder compared to that of Acacia honey which exerted more profound effects in alleviating depression effects and managing glucocorticoids imbalance effects of the stress-depression disorder.


Taken altogether, honey, particularly Tualang, and Acacia honey, used alone or combined with other bee products may be considered functional remedies for the prevention and treatment of depression, pending the confirmation of large sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.

Sources
(1) Bee Honey as a Potentially Effective Treatment for Depression: A Review of Clinical and Preclinical Findings by Amira Mohammed Ali1* and Amin Omar Hendawy. (JOJ Nursing and Health Care)
(2) Potential used of Tualang and Acacia Honey in Ameliorating Stress-Depression Disorder: A Preliminary Study by Qamarul Hafiz Zainol Abidin, Nurul Hanani Mohd. Rujhan, Wan Iryani Wan Ismail. (Researcher Gate)
(3) Life stress as potential risk factor for depression and burnout by Author links open overlay panelT.PliegeraM.MelchersaC.MontagbR.MeermanncM.Reuterad. (Science Direct)

Healthy Food Tomatoes Protect The Cells of Prostate Gland Against Prostate Cancer, Studies Show

Prostate cancer is a medical condition caused by irregular cell growth in the tissues of the prostate.

The prostate is a male reproductive gland that plays a critical role in the contribution of nutrients and fluid to sperm.

Most cases of prostate cancer start in the cells on the surface in the inner lining of the prostate tissue before penetrating into deeper prostate gland layers to induce metastasis via blood and lymph.

At the early stage, due to the very small size of the tumor, prostate cancer is asymptomatic.

The most common symptoms of the prostate at the later stage are frequent urination, weak or interrupted urine flow due to the tumor that affects the tube surrounded by the prostate.


In some cases, patients may experience symptoms of blood in the urine and pain due to the oversize tumor that has pressed on the nearby blood vessels and nerve cells.

The new onset of erectile dysfunction is also common in patients with prostate cancer.

The causes of prostate cancer are not identified. However, the increase in aging is one of the most common risk factors as most cases of the condition are diagnosed in older adults. Approximately, 60% of all cases are diagnosed in men over 65.c


According to the statistics, in 2017, 21,300 men were diagnosed with prostate cancer and the disease cause the death of 4,100 men in the same year.

The 5-year survival rate for most men with local or regional prostate cancer is nearly 100% compared to only 30% in patients diagnosed with prostate cancer that has spread to other parts of the body,

Some researchers concerned that the risk of prostate cancer in the younger population suggested that the promotion of a high-fat diet over the past few decades may be correlated to the rise of the disease.

Dr. Colleen Pelser, the lead scientist wrote, "Total fat and mono- and polyunsaturated fat INTAKES were not associated with the incidence of prostate cancer. Saturated fat intake was related to increased risk of advanced prostate cancer (HRQuintile 5 vs. Quintile 1 (Q1 vs. Q5)1.21; 95% CI 1.00–1.46; p-for-trend=0.03) and fatal prostate cancer".

And. "Our study suggests that the associations of fat and fatty acids differ by prostate cancer severity. Saturated fat, ALA and EPA intakes were related to the risk of advanced or fatal prostate cancer, but not to non-advanced prostate cancer".

The results strongly suggested that if you are a high-fat diet follower, your risk of prostate cancer is increased substantially compared to a traditional diet.

Tomato is red, edible fruit, genus Solanum, belongings to family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.

In the urgency to find a natural compound for the treatment of prostate cancer, researchers investigated the effects of lycopene-rich tomato on prostate-specific antigen (PSA) in prostate cancer patients.

The study included 79 patients with prostate cancer randomized to a nutritional intervention with either 1) tomato products containing 30 mg lycopene per day; 2) tomato products plus selenium, omega-3 fatty acids, soy isoflavones, grape/pomegranate juice, and green/black tea (tomato-plus); or 3) control diet for 3 weeks.

According to the results of the test, the tomato group showed a significant PSA decrease compared to controls.

Compared to other groups, median PSA-values decreased by 1% in patients with the highest increases in plasma lycopene, selenium, and C20:5 n-3 fatty acid, compared to an 8.5% increase in the patients with the lowest increase in lycopene, selenium, and C20:5 n-3 fatty acid.

In other words, PSA decreased the most in patients with the highest increase in lycopene alone.

Based on the findings, researchers said, "Three-week nutritional interventions with tomato-products alone or in combination with selenium and n-3 fatty acids lower PSA in patients with non-metastatic prostate cancer".

Moreover, in the investigation of the association between tomato consumption and prostate cancer risk, researchers at Zhejiang University performed a meta-analysis to comprehensively evaluate this relationship.

Geographically, tomato intake showed significant protective effects in patients of Asian origin and Oceania populations compared to other regions.

According to the total of 24 published studies with 15,099 cases, tomato intake was associated with a reduced risk of prostate cancer with the RRs of 0.76 found in the case-control and cohort studies.


Taken altogether, tomatoes may be considered supplements for the prevention and treatment of prostate cancer, pending the confirmation of the larger sample size and multicenter human study.

Intake of lycopene in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Tomato-based randomized controlled trial in prostate cancer patients: Effect on PSA by Paur I1, Lilleby W2, Bøhn SK3, Hulander E4, Klein W5, Vlatkovic L6, Axcrona K7, Bolstad N8, Bjøro T9, Laake P10, Taskén KA11, Svindland A12, Eri LM13, Brennhovd B14, Carlsen MH15, Fosså SD16, Smeland SS17, Karlsen AS18, Blomhoff R. (PubMed)
(2) Tomato consumption and prostate cancer risk: a systematic review and meta-analysis by Xu X1, Li J1, Wang X1, Wang S1, Meng S1, Zhu Y1, Liang Z1, Zheng X1, Xie L. (PubMed)
(3). Dietary Fat, Fatty Acids and Risk of Prostate Cancer in the NIH-AARP Diet and Health Study
Colleen Pelser,1 Alison M. Mondul,2 Albert R. Hollenbeck,3 and Yikyung Park. (PMC)