Cytotoxicity is the process of the induction of cell death through toxins.
In other words, cell cytotoxicity is the process to use certain chemicals or mediator cells to destroy living cells.
In normal, cytotoxicity can cause the death of healthy cells
In cancers, cytotoxicity can be beneficial to humans by destroying the cancer cells and preventing them from proliferation.
For example, cytotoxicity induced by oxidative stress due to the imbalanced ratio of free radicals and antioxidant enzymes produced by the body can cause protein, lipid, and cellular damage that leads to chronic low-grade inflammatory diseases and cancer.
However, stimulation of ROS and antioxidants production to induce cytotoxicity to the tumors can also cause cancer cell death without damage to nearby healthy cells.
Dr. Shikha Srivastava, the lead scientist in the evaluation of the antioxidant and cytotoxic properties in Quercetin, wrote, "quercetin interacts with DNA directly, and could be one of the mechanisms for inducing apoptosis in both, cancer cell lines and tumor tissues by activating the intrinsic pathway".
And, " quercetin-induced cytotoxicity in leukemic cells in a dose-dependent manner, while ellagic acid showed only limited toxicity. Besides leukemic cells, quercetin also induced cytotoxicity in breast cancer cells, however, its effect on normal cells was limited or none".
Scientifically, most cases of cancer cells cytotoxicity are associated with the stimulation of protein and pathways involved in either gene suppression or cell death programming.
Tomato is red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
In the urgency to find a natural ingredient that kills cancer without inducing adverse effects, researchers examined the toxicity against human gastric adenocarcinoma cells (AGS) and the antioxidant activity of hydroethanolic (HME), acetone (AcE), and alkaloid (AE) extracts prepared from the leaves of the tomato plant.
Both HME and AcE extracts showed a significant effect in scavenging •NO (IC50 values ranged from 0.87 ± 0.12 to 1.54 ± 0.23 and from 0.90 ± 0.01 to 2.23 ± 0.14 mg mL-1, respectively), compared to HMEs that only scavenge O2•- showing IC50 values from 0.12 ± ≤0.01 to 0.43 ± 0.08 mg mL-1.
In other words, tomato extracts demonstrated a strong effect against human gastric adenocarcinoma cells (AGS) through their cytotoxicity without causing harm to normal cells through the antioxidant activity.
Furthermore, in the study to assess different varieties of tomato seed extracts potential antioxidant and/or antiproliferative activity, researchers found that San Marzano Rosso seed extract displays the highest free radical-scavenging activity with 68% of 2,2-Diphenyl-1-picrylhydrazyl radical inhibition.
Moreover, according to the brine shrimp test (LD50: 23,198 ppm), San Marzano Rosso seed extract also demonstrated the highest cytotoxicity against the A375 cell line, compared to other varieties.
Taken altogether, tomato and its leaves may be considered supplements for the prevention and treatment of cancer, pending the confirmation of the larger sample size and multicenter human study.
Intake of tomato in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Further insights on tomato plant: Cytotoxic and antioxidant activity of leaf extracts in human gastric cells by Figueiredo-González M1, Valentão P1, Pereira DM1, Andrade PB. (PubMed)
(2) Antioxidant and cytotoxic activities investigation of tomato seed extracts by Tommonaro G1, Caporale A, De Martino L, Popolo A, De Prisco R, Nicolaus B, Abbamondi GR, Saturnino C. (PubMed)
(3) Quercetin, a Natural Flavonoid Interacts with DNA, Arrests Cell. Cycle and Causes Tumor Regression by Activating Mitochondrial Pathway of Apoptosis by Shikha Srivastava, Ranganatha R. Somasagara, Mahesh Hegde, Mayilaadumveettil Nishana, Satish Kumar Tadi, Mrinal Srivastava, Bibha Choudhary & Sathees C. Raghavan. (Scientific Report)
Get Pregnant Naturally
".....Utilizing Traditional Chinese Medicine in Tonifying Energy flow to the Reproductive System Channels In Men and Women for Natural Conception, including Couple Who were diagnosed with Unexplained causes of Infertility...." Chantel M.
Sunday, February 27, 2022
Saturday, February 19, 2022
Cabbage May Prevent Damages Induced by Myocardial Infarction
Myocardial infarction is a severe medical emergency characterized by the obstruction of the blood supply to the brain, causing local brain neurons to die. Prompt treatment can minimize brain damage and potential post disease complications.
In other words, myocardial infarction (MI) occurs due to the imbalance in oxygen supply and demand caused by plaque rupture with thrombus formation in an artery, leading to reduced blood flow to the heart.
The occurrence and extent of brain infarction are associated with three basic factors, including the site of arterial occlusion, the rapidity of arterial occlusion, and the presence or absence of collateral circulation.
In other words, brain infarction can be classified into myocardial infarction due to plaque rupture and myocardial oxygen supply-demand imbalance secondary to other acute illnesses.
The exact causes of a blood clot to induce acute brain infarction are unknown. Plaques accumulation in the arteries associated with hardening and stiffing arterial walls is a leading cause of cardiovascular disease, including stroke.
According to the statistics provided by the CDC, every year, approximately, about 790,000 Americans have a heart attack, including 580,000 cases of a first heart attack and 210,000 to people who have already had a first heart attack.
The most common symptoms of MI are pressure, tightness, pain, or a squeezing or aching sensation in your chest, digestive discomforts such as nausea, indigestion, heartburn, abdominal pain, shortness of breath, and dizziness.
Conventionally, treatment of myocardial infarction is a focus to reduce the damage of the heart muscle accomplished through medical or mechanical means.
Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem with a crowded mass of leaves, usually green but in some varieties, it may be red or purplish.
On findings a natural whole food for the treatment of post-stroke, researchers examined the effects of anthocyanin-rich red cabbage extract (ARCE) on H2O2 treated rat neonatal cardiomyoblasts (H9c2 cells) and isoproterenol (ISO) induced rodent model of myocardial infarction.
According to the tested analysis,
* H2O2 treated H9c2 cells recorded cytotoxicity (48-50%) and apoptosis (57.3%), compared to the reduction in the presence of ARCE (7-10% & 12.3% respectively).
* Rats pretreated with ARCE for 30 days followed by ISO treatment recorded favorable heart: body weight ratio as compared to ISO treated group.
* Furthermore, the mRNA levels of enzymatic antioxidants (sod and catalase) and apoptotic genes (Bax and BCL-2) in the ARCE+ISO treated group was similar to the control group suggesting that ARCE pretreatment prevents ISO induced depletion of enzymatic antioxidants and apoptosis.
* Moreover, ARCE+ISO treated group (4.5%) recorded results comparable to control (0%) in infracted areas (10%) and derangement of the myocardium.
* ARCE+ISO treated group accounted promote the caveolin-3 associated with the heart muscle and SERCA2a expression involved in the reduced risk of heart failure, compared to the ISO treated group an indication of ARCE in the mediated reduction in membrane damage and calcium imbalance.
Based on the results, researchers wrote, "Overall this study elucidates the mechanism of ARCE mediated prevention of experimentally induced myocardial damage".
Taken altogether, cabbage may be used for the treatment of myocardial infarction, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Anthocyanin rich extract of Brassica oleracea L. alleviates experimentally induced myocardial infarction by Jana S1, Patel D1,2, Patel S1, Upadhyay K1, Thadani J1, Mandal R3, Das S3, Devkar R. (PubMed)
In other words, myocardial infarction (MI) occurs due to the imbalance in oxygen supply and demand caused by plaque rupture with thrombus formation in an artery, leading to reduced blood flow to the heart.
The occurrence and extent of brain infarction are associated with three basic factors, including the site of arterial occlusion, the rapidity of arterial occlusion, and the presence or absence of collateral circulation.
In other words, brain infarction can be classified into myocardial infarction due to plaque rupture and myocardial oxygen supply-demand imbalance secondary to other acute illnesses.
The exact causes of a blood clot to induce acute brain infarction are unknown. Plaques accumulation in the arteries associated with hardening and stiffing arterial walls is a leading cause of cardiovascular disease, including stroke.
According to the statistics provided by the CDC, every year, approximately, about 790,000 Americans have a heart attack, including 580,000 cases of a first heart attack and 210,000 to people who have already had a first heart attack.
The most common symptoms of MI are pressure, tightness, pain, or a squeezing or aching sensation in your chest, digestive discomforts such as nausea, indigestion, heartburn, abdominal pain, shortness of breath, and dizziness.
Conventionally, treatment of myocardial infarction is a focus to reduce the damage of the heart muscle accomplished through medical or mechanical means.
Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem with a crowded mass of leaves, usually green but in some varieties, it may be red or purplish.
On findings a natural whole food for the treatment of post-stroke, researchers examined the effects of anthocyanin-rich red cabbage extract (ARCE) on H2O2 treated rat neonatal cardiomyoblasts (H9c2 cells) and isoproterenol (ISO) induced rodent model of myocardial infarction.
According to the tested analysis,
* H2O2 treated H9c2 cells recorded cytotoxicity (48-50%) and apoptosis (57.3%), compared to the reduction in the presence of ARCE (7-10% & 12.3% respectively).
* Rats pretreated with ARCE for 30 days followed by ISO treatment recorded favorable heart: body weight ratio as compared to ISO treated group.
* Furthermore, the mRNA levels of enzymatic antioxidants (sod and catalase) and apoptotic genes (Bax and BCL-2) in the ARCE+ISO treated group was similar to the control group suggesting that ARCE pretreatment prevents ISO induced depletion of enzymatic antioxidants and apoptosis.
* Moreover, ARCE+ISO treated group (4.5%) recorded results comparable to control (0%) in infracted areas (10%) and derangement of the myocardium.
* ARCE+ISO treated group accounted promote the caveolin-3 associated with the heart muscle and SERCA2a expression involved in the reduced risk of heart failure, compared to the ISO treated group an indication of ARCE in the mediated reduction in membrane damage and calcium imbalance.
Based on the results, researchers wrote, "Overall this study elucidates the mechanism of ARCE mediated prevention of experimentally induced myocardial damage".
Taken altogether, cabbage may be used for the treatment of myocardial infarction, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Anthocyanin rich extract of Brassica oleracea L. alleviates experimentally induced myocardial infarction by Jana S1, Patel D1,2, Patel S1, Upadhyay K1, Thadani J1, Mandal R3, Das S3, Devkar R. (PubMed)
Friday, February 4, 2022
Honey inhibits the Expression of Oxidative Stress with No Side Effects
Scientists may have found a natural alternative for the treatment of diseases associated with oxidative stress, according to studies.
Oxidative stress is a medical condition associated with the overexpression of free radicals compared to low levels of antioxidant enzymes produced by the host.
In fact, free radicals are constantly produced in animal and human cells. The air we breathe, the thing we eat, and the environment we contact are some factors that cause the production of reactive oxygen species (ROS).
Epidemiological studies suggested that oxidative stress can induce damage to the cell, lipid, proteins, and alternation of cell DNA, leading to chronic diseases, such as cardiovascular diseases, diabetes, and particularly, cancer.
How overexpression of free radicals causes damage to the cells. Researchers explained due to free radical unstable nature with unpair of electrons on the out ring of molecules, they constantly seek to donate or intercept the electron from other stable atoms, leading to a chain reaction that can not be stopped until all unpaired electrons are paired or inhibited by antioxidants.
These processes can lead to an imbalance of the ratio of free radicals and antioxidants produced by the host body resulting in oxidative stress, a major cause of cell, lipid, and protein damage.
In spite of free radical's harmful effects, one must understand that cellular oxygen species (ROS), are necessary with a moderate amount to protect our body in the mediation of antimicrobial infection, detoxification of potentially toxic compounds, and elimination of cancerous and other life-threatening cells through cytotoxicity.
On the other hand, antioxidants are stable molecules that inhibit oxidation. Antioxidants can reduce levels of free radicals and overexpression can limit the free radical function in carrying out their health benefits.
Therefore, in order to maintain good health, the levels of free radicals and antioxidants must be balanced.
Honey is a miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered one of the healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.
Researchers on finding a natural compound for the inhibition of oxidative stress examined the honey activity on oxidative stress induced by lead acetate exposure in male Wistar rats.
The study included 24 male Wistar rats randomly divided into four groups: Control group that received 1 ml/kg distilled orally for 28 days; while groups II-IV received 0.2% lead in drinking water and 1 ml/kg of distilled water, 1 ml/kg of honey, 1.5 ml/kg of honey respectively for 28 days.
Before pretreatment with honey, infected rats showed a decrease in locomotor and exploratory and decrease antioxidant activity increase in anxiety, memory impairment, lipid peroxidation.
Co-administration of honey with lead inhibited neurotoxicity observed by the improvement in memory function and decreased latency period and increased in time spent in target quadrant compared to the lead-exposed animals.
Injection of honey in the lead-fed group also increased locomotion, exploration, and decreased anxiety observed by the frequency of rearing, freezing duration, and the number of lines crossed by animals.
More importantly, the administration of honey improved the levels of antioxidant enzymes produced by the host observed by increased brain SOD, GST, and GSH activities compared to the lead-treated groups.
However, the honey pretreatment group showed no significant effect on MDA level, the oxidative stress marker.
These results suggested that honey exerted neuroprotective effects against lead-induced cognitive deficit probably by enhancing antioxidant activities without affecting the levels of MDA.
In order to reveal more information about honey antioxidative stress, researchers investigated the effects of Tualang honey (TH) protective activity against oxidative stress of exercise.
The study included 20 female athletes (aged 21.3 [2.1] years; body weight [BW] 54.1 [5.7] kg) were randomly assigned into two groups and consumed either 1.5 g/kg BW TH (high honey; HH; n = 10) or 0.75 g/kg BW TH (low honey; LH; n = 10).
Injection of Tualang honey showed a reduction of MDA in the LH group compared to the HH group. In other words, less oxidative stress was found in the LH group.
The concentrations of total phenolic content (TPC) and antioxidant activity (ferric reducing antioxidant power [FRAP]) increased from baseline to 2 and 1 h after TH consumption, respectively, then the concentrations returned toward baseline at 3 h in both LH and HH groups.
MDA concentration significantly decreased (p < 0.05) from baseline to 2 h and significantly increased from 2 to 3 h in the HH group. Meanwhile, ROS levels increased significantly from 0.5 to 3 h in the HH group.
Compared to the HH group, the LH group showed similar trends but insignificant increased levels of MDA and ROS.
Taken altogether, honey particularly Tualang honey may be considered functional remedies for the prevention and treatment of diseases related to the expression of oxidative stress with no side effects, pending the confirmation of a large sample size and multicenter human study
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources:
(1) Honey prevents neurobehavioural deficit and oxidative stress induced by lead acetate exposure in male Wistar rats- a preliminary study by Abdulmajeed WI1, Sulieman HB2, Zubayr MO2, Imam A3, Amin A2, Biliaminu SA4, Oyewole LA2, Owoyele BV. (PubMed)
(2) Dose-Response Effect of Tualang Honey on Postprandial Antioxidant Activity and Oxidative Stress in Female Athletes: A Pilot Study by Ahmad NS1, Abdul Aziz A2, Kong KW2, Hamid MSA3, Cheong JPG1, Hamzah SH1. (PubMed)
(3) The benefits and hazards of antioxidants: controlling apoptosis and other protective mechanisms in cancer patients and the human population by Salganik RI. (PubMed)
Oxidative stress is a medical condition associated with the overexpression of free radicals compared to low levels of antioxidant enzymes produced by the host.
In fact, free radicals are constantly produced in animal and human cells. The air we breathe, the thing we eat, and the environment we contact are some factors that cause the production of reactive oxygen species (ROS).
Epidemiological studies suggested that oxidative stress can induce damage to the cell, lipid, proteins, and alternation of cell DNA, leading to chronic diseases, such as cardiovascular diseases, diabetes, and particularly, cancer.
How overexpression of free radicals causes damage to the cells. Researchers explained due to free radical unstable nature with unpair of electrons on the out ring of molecules, they constantly seek to donate or intercept the electron from other stable atoms, leading to a chain reaction that can not be stopped until all unpaired electrons are paired or inhibited by antioxidants.
These processes can lead to an imbalance of the ratio of free radicals and antioxidants produced by the host body resulting in oxidative stress, a major cause of cell, lipid, and protein damage.
In spite of free radical's harmful effects, one must understand that cellular oxygen species (ROS), are necessary with a moderate amount to protect our body in the mediation of antimicrobial infection, detoxification of potentially toxic compounds, and elimination of cancerous and other life-threatening cells through cytotoxicity.
On the other hand, antioxidants are stable molecules that inhibit oxidation. Antioxidants can reduce levels of free radicals and overexpression can limit the free radical function in carrying out their health benefits.
Therefore, in order to maintain good health, the levels of free radicals and antioxidants must be balanced.
Honey is a miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered one of the healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.
Researchers on finding a natural compound for the inhibition of oxidative stress examined the honey activity on oxidative stress induced by lead acetate exposure in male Wistar rats.
The study included 24 male Wistar rats randomly divided into four groups: Control group that received 1 ml/kg distilled orally for 28 days; while groups II-IV received 0.2% lead in drinking water and 1 ml/kg of distilled water, 1 ml/kg of honey, 1.5 ml/kg of honey respectively for 28 days.
Before pretreatment with honey, infected rats showed a decrease in locomotor and exploratory and decrease antioxidant activity increase in anxiety, memory impairment, lipid peroxidation.
Co-administration of honey with lead inhibited neurotoxicity observed by the improvement in memory function and decreased latency period and increased in time spent in target quadrant compared to the lead-exposed animals.
Injection of honey in the lead-fed group also increased locomotion, exploration, and decreased anxiety observed by the frequency of rearing, freezing duration, and the number of lines crossed by animals.
More importantly, the administration of honey improved the levels of antioxidant enzymes produced by the host observed by increased brain SOD, GST, and GSH activities compared to the lead-treated groups.
However, the honey pretreatment group showed no significant effect on MDA level, the oxidative stress marker.
These results suggested that honey exerted neuroprotective effects against lead-induced cognitive deficit probably by enhancing antioxidant activities without affecting the levels of MDA.
In order to reveal more information about honey antioxidative stress, researchers investigated the effects of Tualang honey (TH) protective activity against oxidative stress of exercise.
The study included 20 female athletes (aged 21.3 [2.1] years; body weight [BW] 54.1 [5.7] kg) were randomly assigned into two groups and consumed either 1.5 g/kg BW TH (high honey; HH; n = 10) or 0.75 g/kg BW TH (low honey; LH; n = 10).
Injection of Tualang honey showed a reduction of MDA in the LH group compared to the HH group. In other words, less oxidative stress was found in the LH group.
The concentrations of total phenolic content (TPC) and antioxidant activity (ferric reducing antioxidant power [FRAP]) increased from baseline to 2 and 1 h after TH consumption, respectively, then the concentrations returned toward baseline at 3 h in both LH and HH groups.
MDA concentration significantly decreased (p < 0.05) from baseline to 2 h and significantly increased from 2 to 3 h in the HH group. Meanwhile, ROS levels increased significantly from 0.5 to 3 h in the HH group.
Compared to the HH group, the LH group showed similar trends but insignificant increased levels of MDA and ROS.
Taken altogether, honey particularly Tualang honey may be considered functional remedies for the prevention and treatment of diseases related to the expression of oxidative stress with no side effects, pending the confirmation of a large sample size and multicenter human study
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources:
(1) Honey prevents neurobehavioural deficit and oxidative stress induced by lead acetate exposure in male Wistar rats- a preliminary study by Abdulmajeed WI1, Sulieman HB2, Zubayr MO2, Imam A3, Amin A2, Biliaminu SA4, Oyewole LA2, Owoyele BV. (PubMed)
(2) Dose-Response Effect of Tualang Honey on Postprandial Antioxidant Activity and Oxidative Stress in Female Athletes: A Pilot Study by Ahmad NS1, Abdul Aziz A2, Kong KW2, Hamid MSA3, Cheong JPG1, Hamzah SH1. (PubMed)
(3) The benefits and hazards of antioxidants: controlling apoptosis and other protective mechanisms in cancer patients and the human population by Salganik RI. (PubMed)
Sunday, January 30, 2022
Healthy Food Tomatoes Modulate Immune Function to the Body Needs, Studies Find
The immune system plays a critical role in the body's defense against infectious organisms and other pathogens.
The immune function can be classified into subsystems, including the innate and adaptive responses.
* The innate responses are the general response of the immune system that can act quickly to destroy invaders, regardless of the type of organism.
* The adaptive responses develop slowly on first exposure to a new pathogen slowly. In some cases, it may take a week or so before the responses are effective.
However, due to the quick division of bacteria, (a single bacterium with a doubling time of one hour can produce almost 20 million progeny), therefore, our body is totally dependent on the innate immune system to destroy the invader in the first critical hours and days of exposure.
Believe it or not, if the innate immune subsystem cannot destroy the foreign invader in a set period of time from 3 -8 weeks, it will compromise, leading to low-grade inflammation in facilitating the onset of various diseases, including cardiovascular disease, diabetes, and arthritis.
Immune modulation is the process to increase and decrease immune functioning depending on the needs of the body. In people with a weakened immune system, modulation of the immune system is found to enhance immune functioning against infectious agents.
However, in people with overactive immunity, modulation of the immune function will reduce the risk of the immune system attacking the body tissues.
Tomato is red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
With an aim to find a potential compound with immune-modulatory activity, researchers examined the influence of tomato aqueous extract (TAE) on the in vitro inflammatory response.
According to the results observed by the Murine macrophages (RAW264.7 cells), PBLs and HUVECs incubated with TAE, TAE exerted a significant effect in the inhibition of pro-inflammatory cytokines such as L-1β, IL-6, IL-10, IL-12 and chemokines such as CCL2/MCP-1, CCL3/MIP-1α.
In the endothelial cell, TAE reduced ED-associated expression of adhesion molecules (ICAM-1, VCAM-1) associated with the production of inflammation.
In macrophages, the production of pro-inflammatory proteins associated with low-grade inflammation also inhibited the injection of TAE.
Based on the findings, researchers said, "during acute inflammation, TAE enhances cellular alertness and therefore the sensing of disturbed immune homeostasis in the vascular-endothelial compartment. Conversely, it blunts inflammatory mediators in macrophages during chronic inflammation".
In other words, TAE protects the integrity and viability of immune cells by modulating the immune activity depending on the needs of the body.
Furthermore, in a blinded, randomized, cross-over study, male subjects on a low-carotenoid diet consumed 330 ml/day of either tomato juice (37.0 mg/day lycopene) or carrot juice (27.1 mg/day beta-carotene and 13.1 mg/day alpha-carotene) for 2 weeks with a 2-week depletion period after juice intervention, researchers compared the effects of a low-carotenoid diet supplemented with either tomato (providing high amounts of lycopene) or carrot juice (providing high amounts of alpha- and beta-carotene) on immune functions in healthy man.
According to the results from the tested assays, juice consumption showed relatively fast responses in plasma carotenoid concentrations (p < 0.0002) without being accompanied by concomitant changes in immune functions.
However, increased plasma carotenoid concentrations after vegetable juice consumption were accompanied by a time-delayed modulation of immune functions in healthy men consuming a low-carotenoid diet.
Precisely, tomato juice modulated the immune function in a delay and concentration-dependent manner.
Taken altogether, tomatoes may be considered supplements for the modulation of immune function based on the body needs, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Tomato Aqueous Extract Modulates the Inflammatory Profile of Immune Cells and Endothelial Cells by Schwager J1, Richard N2, Mussler B3, Raederstorff D. (PubMed)
(2) Supplementation of a low-carotenoid diet with tomato or carrot juice modulates immune functions in healthy men by Watzl B1, Bub A, Briviba K, Rechkemmer G. (PubMed)
The immune function can be classified into subsystems, including the innate and adaptive responses.
* The innate responses are the general response of the immune system that can act quickly to destroy invaders, regardless of the type of organism.
* The adaptive responses develop slowly on first exposure to a new pathogen slowly. In some cases, it may take a week or so before the responses are effective.
However, due to the quick division of bacteria, (a single bacterium with a doubling time of one hour can produce almost 20 million progeny), therefore, our body is totally dependent on the innate immune system to destroy the invader in the first critical hours and days of exposure.
Believe it or not, if the innate immune subsystem cannot destroy the foreign invader in a set period of time from 3 -8 weeks, it will compromise, leading to low-grade inflammation in facilitating the onset of various diseases, including cardiovascular disease, diabetes, and arthritis.
Immune modulation is the process to increase and decrease immune functioning depending on the needs of the body. In people with a weakened immune system, modulation of the immune system is found to enhance immune functioning against infectious agents.
However, in people with overactive immunity, modulation of the immune function will reduce the risk of the immune system attacking the body tissues.
Tomato is red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
With an aim to find a potential compound with immune-modulatory activity, researchers examined the influence of tomato aqueous extract (TAE) on the in vitro inflammatory response.
According to the results observed by the Murine macrophages (RAW264.7 cells), PBLs and HUVECs incubated with TAE, TAE exerted a significant effect in the inhibition of pro-inflammatory cytokines such as L-1β, IL-6, IL-10, IL-12 and chemokines such as CCL2/MCP-1, CCL3/MIP-1α.
In the endothelial cell, TAE reduced ED-associated expression of adhesion molecules (ICAM-1, VCAM-1) associated with the production of inflammation.
In macrophages, the production of pro-inflammatory proteins associated with low-grade inflammation also inhibited the injection of TAE.
Based on the findings, researchers said, "during acute inflammation, TAE enhances cellular alertness and therefore the sensing of disturbed immune homeostasis in the vascular-endothelial compartment. Conversely, it blunts inflammatory mediators in macrophages during chronic inflammation".
In other words, TAE protects the integrity and viability of immune cells by modulating the immune activity depending on the needs of the body.
Furthermore, in a blinded, randomized, cross-over study, male subjects on a low-carotenoid diet consumed 330 ml/day of either tomato juice (37.0 mg/day lycopene) or carrot juice (27.1 mg/day beta-carotene and 13.1 mg/day alpha-carotene) for 2 weeks with a 2-week depletion period after juice intervention, researchers compared the effects of a low-carotenoid diet supplemented with either tomato (providing high amounts of lycopene) or carrot juice (providing high amounts of alpha- and beta-carotene) on immune functions in healthy man.
According to the results from the tested assays, juice consumption showed relatively fast responses in plasma carotenoid concentrations (p < 0.0002) without being accompanied by concomitant changes in immune functions.
However, increased plasma carotenoid concentrations after vegetable juice consumption were accompanied by a time-delayed modulation of immune functions in healthy men consuming a low-carotenoid diet.
Precisely, tomato juice modulated the immune function in a delay and concentration-dependent manner.
Taken altogether, tomatoes may be considered supplements for the modulation of immune function based on the body needs, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Tomato Aqueous Extract Modulates the Inflammatory Profile of Immune Cells and Endothelial Cells by Schwager J1, Richard N2, Mussler B3, Raederstorff D. (PubMed)
(2) Supplementation of a low-carotenoid diet with tomato or carrot juice modulates immune functions in healthy men by Watzl B1, Bub A, Briviba K, Rechkemmer G. (PubMed)
Sunday, January 23, 2022
Antioxidant Omega 3 Fatty Acids Suppress Cancer Cachexia in Patients with Pancreatic Cancer
The pancreas is an oblong flattened gland in the digestive and endocrine system located in the abdomen. By secreting pancreatic juice to the small intestine, the pancreas helps to break down carbohydrates, proteins, and lipids.
Traditional Chinese medicine views the pancreas, as a vital organ that is responsible for the absorption of foods' qi and nutrients before passing them to other organs to nourish our body.
More precisely, the functions of the pancreas including
* Production of enzymes digest fat, protein, and
carbohydrates.
* production of juices combined with juices from the intestines helps to do the job of breaking down protein, carbohydrates, and fat, therefore, it plays an important role in maintaining good health.
* Production of insulin, which is important in regulating the amount of sugar or glucose in the blood.
Pancreatic cancer is a chronic condition characterized by cell growth irregularly in the tissues of the pancreas.
According to statistics, every year, approximately, 55,000 adults in the United States are diagnosed with pancreatic cancer, accounting for 3% of all cancers and 7% of all cancer deaths.
The survival rate of pancreatic cancer even diagnosed early is very low compared to other types of cancer. The 5-year survival rate at stage IA pancreatic cancer is only14%.
Researchers do not know what causes pancreatic cancer. They don't even know why people with the same health conditions in the same family, are susceptible to pancreatic cancer, while others do not.
The most common risk factors of pancreatic cancer are similar to those of common cancers, including age, family history, gender, ethnicity, smoking, being overweight or obesity, and certain medical conditions such as diabetes.
Cancer cachexia is a condition a multifactorial syndrome associated with an ongoing loss of skeletal muscle mass.
Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.
The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).
On finding a potential phytochemical for the treatment of cancer, researchers examined the effects of omega-3 fatty acids in patients with pancreatic and bile duct cancer.
According to the administration of Racol®, an enteral nutrient formulated with omega-3 fatty acids to patients with unresectable pancreatic and bile duct cancer at 4 and 8 weeks after, pre-administration and administration showed a strong activity that increases skeletal muscle mass at both 4 and 8 weeks.
In other words, Omega-3 fatty acid supplementation protects the skeletal muscle mass associated with cancer cachexia in patients with unresectable pancreatic cancer may improve cancer.
Taken altogether, Omega-3 fatty acids found abundantly in fish oil and plant oil may be considered a functional food for the reduction of cancer cachexia in patients with pancreatic cancer, pending the confirmation of the larger sample size and multicenter human study.
Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Omega-3 Fatty Acids Prevent Early Pancreatic Carcinogenesis via Repression of the AKT Pathway by Ding Y1, Mullapudi B2, Torres C3, Mascariñas E4,5, Mancinelli G6, Diaz AM7, McKinney R8, Barron M9, Schultz M10,11, Heiferman M12, Wojtanek M13, Adrian K14, DeCant B15,16, Rao S17, Ouellette M18, Tsao MS19, Bentrem DJ20, Grippo PJ. (PubMed)
(2) Effects of ω-3 Fatty Acid Supplementation in Patients with Bile Duct or Pancreatic Cancer Undergoing Chemotherapy by Abe K1, Uwagawa T2, Haruki K2, Takano Y2, Onda S2, Sakamoto T2, Gocho T2, Yanaga K. (PubMed)
Traditional Chinese medicine views the pancreas, as a vital organ that is responsible for the absorption of foods' qi and nutrients before passing them to other organs to nourish our body.
More precisely, the functions of the pancreas including
* Production of enzymes digest fat, protein, and
carbohydrates.
* production of juices combined with juices from the intestines helps to do the job of breaking down protein, carbohydrates, and fat, therefore, it plays an important role in maintaining good health.
* Production of insulin, which is important in regulating the amount of sugar or glucose in the blood.
Pancreatic cancer is a chronic condition characterized by cell growth irregularly in the tissues of the pancreas.
According to statistics, every year, approximately, 55,000 adults in the United States are diagnosed with pancreatic cancer, accounting for 3% of all cancers and 7% of all cancer deaths.
The survival rate of pancreatic cancer even diagnosed early is very low compared to other types of cancer. The 5-year survival rate at stage IA pancreatic cancer is only14%.
Researchers do not know what causes pancreatic cancer. They don't even know why people with the same health conditions in the same family, are susceptible to pancreatic cancer, while others do not.
The most common risk factors of pancreatic cancer are similar to those of common cancers, including age, family history, gender, ethnicity, smoking, being overweight or obesity, and certain medical conditions such as diabetes.
Cancer cachexia is a condition a multifactorial syndrome associated with an ongoing loss of skeletal muscle mass.
Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.
The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).
On finding a potential phytochemical for the treatment of cancer, researchers examined the effects of omega-3 fatty acids in patients with pancreatic and bile duct cancer.
According to the administration of Racol®, an enteral nutrient formulated with omega-3 fatty acids to patients with unresectable pancreatic and bile duct cancer at 4 and 8 weeks after, pre-administration and administration showed a strong activity that increases skeletal muscle mass at both 4 and 8 weeks.
In other words, Omega-3 fatty acid supplementation protects the skeletal muscle mass associated with cancer cachexia in patients with unresectable pancreatic cancer may improve cancer.
Taken altogether, Omega-3 fatty acids found abundantly in fish oil and plant oil may be considered a functional food for the reduction of cancer cachexia in patients with pancreatic cancer, pending the confirmation of the larger sample size and multicenter human study.
Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Omega-3 Fatty Acids Prevent Early Pancreatic Carcinogenesis via Repression of the AKT Pathway by Ding Y1, Mullapudi B2, Torres C3, Mascariñas E4,5, Mancinelli G6, Diaz AM7, McKinney R8, Barron M9, Schultz M10,11, Heiferman M12, Wojtanek M13, Adrian K14, DeCant B15,16, Rao S17, Ouellette M18, Tsao MS19, Bentrem DJ20, Grippo PJ. (PubMed)
(2) Effects of ω-3 Fatty Acid Supplementation in Patients with Bile Duct or Pancreatic Cancer Undergoing Chemotherapy by Abe K1, Uwagawa T2, Haruki K2, Takano Y2, Onda S2, Sakamoto T2, Gocho T2, Yanaga K. (PubMed)
Saturday, January 15, 2022
Healthy Food Honey, the Best for the Treatment of Chronic Cough with No Side Effects
Scientists may have found a natural alternative for the treatment of chronic cough, according to studies.
Cough is a natural human reflex that clears the throat of mucus or foreign irritants.
Although it is not common, coughing also is used to clear foreign substances and irritants infrequently associated with a certain lung infection.
Unlike an acute cough, chronic cough is a cough that lasts more than eight weeks. The most common causes of a chronic cough are a postnasal drip, asthma, and acid reflux.
Believe it or not, postnasal drip, asthma, and acid reflux are found in 90% of patients with a chronic cough.
According to the statistic, approximately, 2.% of US adults suffer from a chronic cough, and the risk of chronic cough of current smokers is substantially higher compared to non-smokers.
Besides smoking, people with chronic lung diseases such as asthma, bronchiectasis, COPD, and previous lung infections with scars are also at increased risk of developing a chronic cough.
Some researchers suggested that obese children may also be at risk of chronic conditions.
Dr. S Deane, the lead scientist in the assessment of the obese risk of chronic cough in children said, "Obese children have more respiratory symptoms than their normal-weight peers and respiratory-related pathology increases with increasing weight"
And, "Some will need specialist assessment (box 1). Obesity produces mechanical effects on respiratory system performance. Breathlessness, wheeze, and cough are not related to increased airway responsiveness and may respond more to weight loss than bronchodilator therapy. A significant number of obese children have signs and symptoms of obstructive sleep apnoea largely related to the effect of obesity on upper airway dimensions".
These results strongly suggested that the increased weight of obese children is the major risk factor on the development of chronic cough.
Honey is a miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered one of the healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.
Scientists searching for a natural remedy for the treatment of a chronic cough without inducing adverse effects compared the effects of a single nocturnal dose of 3 honey products (eucalyptus honey, citrus honey, or Labiatae honey) to placebo (silan date extract) on nocturnal cough associated with childhood upper respiratory tract infections (URIs).
The study included 300 children aged 1 to 5 years with URIs, nocturnal cough, and illness duration of ≤ 7 days from 6 general pediatric community clinics. Eligible children received a single dose of 10 g of eucalyptus honey, citrus honey, Labiatae honey, or placebo administered 30 minutes before bedtime.
According to the results from 2 consecutive days, there was a significant improvement from the night before treatment to the night of treatment in the treatment group compared to the placebo.
Furthermore, according to the parents' review, the honey exhibited a higher than the silan date extract for symptomatic relief for their children's nocturnal cough and sleep difficulty.
In order to reveal more information about honey against a chronic cough in children, researchers examined the honey effect in the persistent post-infectious cough (PPC) that lasts more than three weeks or perhaps for many months.
The double-blind randomized controlled trial was conducted from 2008 to 2011 at the Baqiyatallah University Hospital, Tehran, Iran. included 97 adults who experienced PPC for more than three weeks randomly distributed into three groups.
Participants were given either a jam-like paste included honey plus coffee for the first group ('HC'), orprednisolone for the second group (steroid, 'S'), or guaifenesin for the third group (control, 'C').
All participants were told to dissolve a specified amount of their product in warm water and drink the solution every eight hours for one week.
The mean (+/- SD) cough scores pre- and post-treatment were: HC group 2.9 (0.3) pre-treatment and 0.2 (0.5) post-treatment (p < 0.001), and steroid ('S') group 3.0 (0.0) pre-treatment and 2.4 (0.6) post-treatment (p < 0.05)
The control ('C') group exerted mean (+/- SD) cough scores of 2.8 (0.4) pre-treatment and 2.7 (0.5) post-treatment (p > 0.05).
By Analysing the variance, researchers found that there is a significant difference between the mean cough frequency before and after treatment in the HC group, compared in the S group
Honey plus coffee was found to be the most effective modality for PPC, compared to other groups.
Taken altogether, honey may be considered an alternative remedy for the prevention and treatment of chronic coughs in children and adults, pending the confirmation of large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Effect of honey on nocturnal cough and sleep quality: a double-blind, randomized, placebo-controlled study by Cohen HA1, Rozen J, Kristal H, Laks Y, Berkovitch M, Uziel Y, Kozer E, Pomeranz A, Efrat H. (PubMed)
(2) Honey plus coffee versus systemic steroid in the treatment of persistent post-infectious cough: a randomised controlled trial by Raeessi MA1, Aslani J, Raeessi N, Gharaie H, Karimi Zarchi AA, Raeessi F. (PubMed)
(3) Obesity and the pulmonologist by S Deane and A Thomson. (PMC)
Cough is a natural human reflex that clears the throat of mucus or foreign irritants.
Although it is not common, coughing also is used to clear foreign substances and irritants infrequently associated with a certain lung infection.
Unlike an acute cough, chronic cough is a cough that lasts more than eight weeks. The most common causes of a chronic cough are a postnasal drip, asthma, and acid reflux.
Believe it or not, postnasal drip, asthma, and acid reflux are found in 90% of patients with a chronic cough.
According to the statistic, approximately, 2.% of US adults suffer from a chronic cough, and the risk of chronic cough of current smokers is substantially higher compared to non-smokers.
Besides smoking, people with chronic lung diseases such as asthma, bronchiectasis, COPD, and previous lung infections with scars are also at increased risk of developing a chronic cough.
Some researchers suggested that obese children may also be at risk of chronic conditions.
Dr. S Deane, the lead scientist in the assessment of the obese risk of chronic cough in children said, "Obese children have more respiratory symptoms than their normal-weight peers and respiratory-related pathology increases with increasing weight"
And, "Some will need specialist assessment (box 1). Obesity produces mechanical effects on respiratory system performance. Breathlessness, wheeze, and cough are not related to increased airway responsiveness and may respond more to weight loss than bronchodilator therapy. A significant number of obese children have signs and symptoms of obstructive sleep apnoea largely related to the effect of obesity on upper airway dimensions".
These results strongly suggested that the increased weight of obese children is the major risk factor on the development of chronic cough.
Honey is a miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered one of the healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.
Scientists searching for a natural remedy for the treatment of a chronic cough without inducing adverse effects compared the effects of a single nocturnal dose of 3 honey products (eucalyptus honey, citrus honey, or Labiatae honey) to placebo (silan date extract) on nocturnal cough associated with childhood upper respiratory tract infections (URIs).
The study included 300 children aged 1 to 5 years with URIs, nocturnal cough, and illness duration of ≤ 7 days from 6 general pediatric community clinics. Eligible children received a single dose of 10 g of eucalyptus honey, citrus honey, Labiatae honey, or placebo administered 30 minutes before bedtime.
According to the results from 2 consecutive days, there was a significant improvement from the night before treatment to the night of treatment in the treatment group compared to the placebo.
Furthermore, according to the parents' review, the honey exhibited a higher than the silan date extract for symptomatic relief for their children's nocturnal cough and sleep difficulty.
In order to reveal more information about honey against a chronic cough in children, researchers examined the honey effect in the persistent post-infectious cough (PPC) that lasts more than three weeks or perhaps for many months.
The double-blind randomized controlled trial was conducted from 2008 to 2011 at the Baqiyatallah University Hospital, Tehran, Iran. included 97 adults who experienced PPC for more than three weeks randomly distributed into three groups.
Participants were given either a jam-like paste included honey plus coffee for the first group ('HC'), orprednisolone for the second group (steroid, 'S'), or guaifenesin for the third group (control, 'C').
All participants were told to dissolve a specified amount of their product in warm water and drink the solution every eight hours for one week.
The mean (+/- SD) cough scores pre- and post-treatment were: HC group 2.9 (0.3) pre-treatment and 0.2 (0.5) post-treatment (p < 0.001), and steroid ('S') group 3.0 (0.0) pre-treatment and 2.4 (0.6) post-treatment (p < 0.05)
The control ('C') group exerted mean (+/- SD) cough scores of 2.8 (0.4) pre-treatment and 2.7 (0.5) post-treatment (p > 0.05).
By Analysing the variance, researchers found that there is a significant difference between the mean cough frequency before and after treatment in the HC group, compared in the S group
Honey plus coffee was found to be the most effective modality for PPC, compared to other groups.
Taken altogether, honey may be considered an alternative remedy for the prevention and treatment of chronic coughs in children and adults, pending the confirmation of large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Effect of honey on nocturnal cough and sleep quality: a double-blind, randomized, placebo-controlled study by Cohen HA1, Rozen J, Kristal H, Laks Y, Berkovitch M, Uziel Y, Kozer E, Pomeranz A, Efrat H. (PubMed)
(2) Honey plus coffee versus systemic steroid in the treatment of persistent post-infectious cough: a randomised controlled trial by Raeessi MA1, Aslani J, Raeessi N, Gharaie H, Karimi Zarchi AA, Raeessi F. (PubMed)
(3) Obesity and the pulmonologist by S Deane and A Thomson. (PMC)
Saturday, January 8, 2022
Healthyfood Honey, the Natural Pain Reliever with No Side Effects
Scientists may have found a natural alternative pain relief remedy for alleviating pain, according to studies. found.
Pain relief is an action to remove pain, distress, oppression by blocking the pain-transmitting information from nerve cells to the brain neurons.
Acute pain is any pain that lasts less than 6 months. Most cases of acute pain are due to physical damage such as soft tissue damage of a sprained ankle or a paper cut. Acute pain is relatively more sharp and severe.
On the other hand, there are many risk factors associated with chronic pain. Some chronic pains can be caused by single factors such as diseases involving nerve damage to injuries that fail to heal properly. Others may result from several factors including diseases associated with normal aging.
Over-the-counter medications used for the treatment of pain includes acetaminophen (Tylenol) and nonsteroidal anti-inflammatory drugs (NSAIDs).
Besides the gastrointestinal discomforts, long-term use of Tylenol may be additive. Overdoses or consumption together with alcohol, Tylenol can cause liver damage in severe cases.
If you are taking some over-the-counter medicine for pain-relieving, please make sure you know all the side effects of the preventive measure.
Honey is a miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered one of the healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.
Researchers on finding a natural ingredient for pain relief examined the honey effect as adjunct pain therapy.
The pain relief of honey was the result of the contribution of the numerous phytochemicals and components, including the interaction of protein, amino acid, flavonoids, phenolics, organic acid, pigment, water, and (high) sugar content in honey.
These components work together to relieve pain by exerting antibacterial, antiinflammation, and immunomodulation properties.
According to additional differentiation, honey reduced pain through the expression of the level of the central and peripheral nervous system or at the autonomic receptor sites involved in pain transmission via the cyclooxygenase pathway in nociception and pain.
Furthermore, in the examined the honey pain relief in post-tonsillectomy treatment with or without adenoidectomy, researchers launched a randomized, double-blind, placebo-controlled study that included 140 patients, who were older than eight.
Patients were divided into two equal groups, honey, and placebo.
Compared the acetaminophen plus honey for the honey group, and acetaminophen plus placebo for the placebo group, researchers found that
* According to the visual analog scale (VAS) and a number of painkillers taken within the first three postoperative days, acetaminophen and acetaminophen plus honey groups showed a statistically significant reduction of pain.
*The reduced use of painkillers differed significantly in every five postoperative days.
* Pain awoke at night is also reduced with no difference between groups.
* Honey injection exerted negligible side effects
These results strongly showed that postoperative honey administration reduces postoperative pain and analgesic requirements in patients after tonsillectomy.
Taken all together, there is no doubt that honey may be considered a functional remedy for pain relief with few side effects, pending the confirmation of large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Chapter 10 - Honey—A Natural Remedy for Pain Relief by Author links open overlay panelN.M.LazimA.Baharudin. (PubMed)
(2) Post Tonsillectomy Pain: Can Honey Reduce the Analgesic Requirements? by Peyman Boroumand,1 Mohammad Mahdi Zamani,2 Masoumeh Saeedi,1Omid Rouhbakhshfar,1 Seyed Reza Hosseini Motlagh,1 and Fatemeh Aarabi Moghaddam. (PubMed)
Pain relief is an action to remove pain, distress, oppression by blocking the pain-transmitting information from nerve cells to the brain neurons.
Acute pain is any pain that lasts less than 6 months. Most cases of acute pain are due to physical damage such as soft tissue damage of a sprained ankle or a paper cut. Acute pain is relatively more sharp and severe.
On the other hand, there are many risk factors associated with chronic pain. Some chronic pains can be caused by single factors such as diseases involving nerve damage to injuries that fail to heal properly. Others may result from several factors including diseases associated with normal aging.
Over-the-counter medications used for the treatment of pain includes acetaminophen (Tylenol) and nonsteroidal anti-inflammatory drugs (NSAIDs).
Besides the gastrointestinal discomforts, long-term use of Tylenol may be additive. Overdoses or consumption together with alcohol, Tylenol can cause liver damage in severe cases.
If you are taking some over-the-counter medicine for pain-relieving, please make sure you know all the side effects of the preventive measure.
Honey is a miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered one of the healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.
Researchers on finding a natural ingredient for pain relief examined the honey effect as adjunct pain therapy.
The pain relief of honey was the result of the contribution of the numerous phytochemicals and components, including the interaction of protein, amino acid, flavonoids, phenolics, organic acid, pigment, water, and (high) sugar content in honey.
These components work together to relieve pain by exerting antibacterial, antiinflammation, and immunomodulation properties.
According to additional differentiation, honey reduced pain through the expression of the level of the central and peripheral nervous system or at the autonomic receptor sites involved in pain transmission via the cyclooxygenase pathway in nociception and pain.
Furthermore, in the examined the honey pain relief in post-tonsillectomy treatment with or without adenoidectomy, researchers launched a randomized, double-blind, placebo-controlled study that included 140 patients, who were older than eight.
Patients were divided into two equal groups, honey, and placebo.
Compared the acetaminophen plus honey for the honey group, and acetaminophen plus placebo for the placebo group, researchers found that
* According to the visual analog scale (VAS) and a number of painkillers taken within the first three postoperative days, acetaminophen and acetaminophen plus honey groups showed a statistically significant reduction of pain.
*The reduced use of painkillers differed significantly in every five postoperative days.
* Pain awoke at night is also reduced with no difference between groups.
* Honey injection exerted negligible side effects
These results strongly showed that postoperative honey administration reduces postoperative pain and analgesic requirements in patients after tonsillectomy.
Taken all together, there is no doubt that honey may be considered a functional remedy for pain relief with few side effects, pending the confirmation of large sample size and multicenter human study.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Chapter 10 - Honey—A Natural Remedy for Pain Relief by Author links open overlay panelN.M.LazimA.Baharudin. (PubMed)
(2) Post Tonsillectomy Pain: Can Honey Reduce the Analgesic Requirements? by Peyman Boroumand,1 Mohammad Mahdi Zamani,2 Masoumeh Saeedi,1Omid Rouhbakhshfar,1 Seyed Reza Hosseini Motlagh,1 and Fatemeh Aarabi Moghaddam. (PubMed)
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