Intake of coffee regularly may have a positive effect in reduced risk of Melanoma, particularly in healthy people with alternated genes GSTM1 and GSTT1 expression, a renowned institute study suggested.
Melanoma is a type of malignant skin cancer caused by DNA damage, most often caused by ultraviolet radiation from sunshine or tanning beds inducing irregular growth of skin cells.
Coffee, becoming a popular and social beverage all over the world, particularly in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.
According to the Istituto Dermopatico dell Immacolata, in comparison to low coffee intake, high frequency of coffee drinking (>once daily) with ≤7 times weekly, showed a significantly lower risk of melanoma.
Interestingly, in the group of people with GSTM1 and GSTT1 null polymorphisms(altered gene expression) subjects, coffees showed an extremely high protective effect against the forming of Melanoma.
Also in the searching of PubMed and EMBASE databases from the earliest available online indexing year to March 2017 for a dose-response meta-analysis on prospective cohort studies, researchers at the Jagiellonian University Medical College, insisted that linear dose-dependent are associated with the development of melanoma risk and total coffee consumption.
The risk of melanoma is reduced by 3% for every cup of coffee intake per day.
Dr. Micek A, the lead author in the joint study said, "(According to) a total of seven studies eligible for meta-analysis were identified that comprised 1,418,779 participants and 9211 melanoma cases,......coffee intake may be inversely associated with the incidence of melanoma".
Further in the demonstration of 2 case-control studies (846 MM patients and 843 controls) and five cohort studies (including 844,246 participants and 5,737 MM cases), in compared the lower and higher caffeine intake daily, caffeinated coffee showed a pooled relative risk (RR) of 0.81.
Risk of an additional cup of coffee caffeine consumption, the relative odds ratio of the risk of melanoma decreased by 0.955
Importantly, the study found no correlated and linear dose-dependent of decaffeinating coffee and risk melanoma regardless of the volume of daily intake in teasing subjects.
Taking all together, there is no doubt that caffeine coffee has a significant effect in reducing the risk of melanoma in healthy and altered GSTM1 and GSTT1 expression subjects in linearly dose-dependent
manner.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Author biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) The protective effect of coffee consumption on cutaneous melanoma risk and the role of GSTM1 and GSTT1 polymorphisms by Fortes C1, Mastroeni S, Boffetta P, Antonelli G, Pilla MA, Bottà G, Anzidei P, Venanzetti F.(PubMed)
(2) Caffeinated and decaffeinated coffee consumption and melanoma risk: a dose-response meta-analysis of prospective cohort studies by Micek A1, Godos J2, Lafranconi A3, Marranzano M2, Pajak A1(PubMed).
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Friday, December 4, 2020
Friday, October 23, 2020
Brassica Oleracea Vegetables Kills Colorectal cancer Cells in Vitro
The colon-rectum formed a part of the digestive system is involved in the absorption of water from the small bowel contents and broken down certain materials in the feces into substances of which some of them to be reabsorbed and reused by the body.
Cancer is a class of diseases characterized by the irregular cell growth on the body tissue, due to the alternation of cell DNA.
Colorectal cancer is a medical condition caused by cell growth irregularly in the tissue of the colon or rectum due to the alternation of cells DNA.
According to the statistics provided by the American Cancer Society, in the US, colorectal cancer is the third most common cancer diagnosed in both men and women compared to other types of cancer.
The lifetime risk of colorectal cancer is 1 in 22 (4.49%) for men and 1 in 24 (4.15%) for women.
Approximately, 140,000 cases of colorectal cancer were diagnosed in the US in 2018. Colorectal Cancer also causes the death of over 50, 000 people, representing 8.3% of total cancer death.
Being overweight or obese. smoking, physical inactivity, excessive alcohol drinking, the increase in age, family and personal history, genetic preposition are some of the prevalent risks of the disease.
Overall, the lifetime risk of colorectal cancer developing is 1 in 22 (4.49%) in men and 1 in 24 (4.15%) in women.
On finding a potential wholefood for the treatment of cancer, researchers examined the effect of principle bioactive compounds, isothiocyanates (ITCs) on a colorectal cancer cell line (HT-29).
According to the chemicals analysis, purple cabbage extract showed the highest ITC concentration per gram, fresh weight, followed by black cabbage and Romanesco cauliflower.
ITC at the concentrations of 7.08 microg/mL decreased cancer cell viability by inducing the caspase-3 associated with cell death and DNA fragmentation at 48h.
Brussels sprouts showed the strongest effects on cell viability and caspase-3 activity.
Furthermore, all varieties of Brassica Oleracea with rich sources of ITCs potently inhibit the growth of colon cancer cells by inducing apoptosis.
All the extracts showed anticancer activity at ITC concentrations of between 3.54 to 7.08 mug/mL,
Based on the finding, researchers said, " ITC concentration and the chemopreventive responses of plant extracts vary among the varieties of Brassica Oleracea studied and among their cultivars".
Taken altogether, Brassica Oleracea vegetables may be considered functional foods for the prevention and treatment of colorectal cancer, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Induction of apoptosis in HT-29 cells by extracts from isothiocyanates-rich varieties of Brassica oleracea by Mas S1, Crescenti A, Gassó P, Deulofeu R, Molina R, Ballesta A, Kensler TW, Lafuente A. (PubMed)
Cancer is a class of diseases characterized by the irregular cell growth on the body tissue, due to the alternation of cell DNA.
Colorectal cancer is a medical condition caused by cell growth irregularly in the tissue of the colon or rectum due to the alternation of cells DNA.
According to the statistics provided by the American Cancer Society, in the US, colorectal cancer is the third most common cancer diagnosed in both men and women compared to other types of cancer.
The lifetime risk of colorectal cancer is 1 in 22 (4.49%) for men and 1 in 24 (4.15%) for women.
Approximately, 140,000 cases of colorectal cancer were diagnosed in the US in 2018. Colorectal Cancer also causes the death of over 50, 000 people, representing 8.3% of total cancer death.
Being overweight or obese. smoking, physical inactivity, excessive alcohol drinking, the increase in age, family and personal history, genetic preposition are some of the prevalent risks of the disease.
Overall, the lifetime risk of colorectal cancer developing is 1 in 22 (4.49%) in men and 1 in 24 (4.15%) in women.
On finding a potential wholefood for the treatment of cancer, researchers examined the effect of principle bioactive compounds, isothiocyanates (ITCs) on a colorectal cancer cell line (HT-29).
According to the chemicals analysis, purple cabbage extract showed the highest ITC concentration per gram, fresh weight, followed by black cabbage and Romanesco cauliflower.
ITC at the concentrations of 7.08 microg/mL decreased cancer cell viability by inducing the caspase-3 associated with cell death and DNA fragmentation at 48h.
Brussels sprouts showed the strongest effects on cell viability and caspase-3 activity.
Furthermore, all varieties of Brassica Oleracea with rich sources of ITCs potently inhibit the growth of colon cancer cells by inducing apoptosis.
All the extracts showed anticancer activity at ITC concentrations of between 3.54 to 7.08 mug/mL,
Based on the finding, researchers said, " ITC concentration and the chemopreventive responses of plant extracts vary among the varieties of Brassica Oleracea studied and among their cultivars".
Taken altogether, Brassica Oleracea vegetables may be considered functional foods for the prevention and treatment of colorectal cancer, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Induction of apoptosis in HT-29 cells by extracts from isothiocyanates-rich varieties of Brassica oleracea by Mas S1, Crescenti A, Gassó P, Deulofeu R, Molina R, Ballesta A, Kensler TW, Lafuente A. (PubMed)
Tuesday, October 20, 2020
Green Tea may Serve as Functional Food in Reduced early Onset and Treatment of Hypercholesterolemia
Green tea may be the next potential functional food used in reduced risk of early-onset and treatment of high blood cholesterol, a renowned institute study suggested.
Hypercholesterolemia is a condition of abnormally high levels of cholesterol in the bloodstream.
Green tea, a precious drink processes number of health benefits known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine, or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory.
According to the University of Agriculture, ethanolic extracts of green tea fed mice in 8 weeks in vivo model expressed significant effects in normalized levels of cholesterol in hypercholesterolemic rats up to 15.45% in comparison control.
The study also revealed that the administration of green tea does not adversely affect the red blood cell, white blood cell, and platelet count of the tested rats.
Additionally, in compared efficacy of black tea (BT) and green tea (GT) in serum and hepatic oxidative abnormalities in hypercholesterolemic rats, after 8 weeks, green and black tea fed groups displayed a significantly lower levels of serum and hepatic cholesterol, triglycerides, serum low-density lipoprotein cholesterol, and increased high-density lipoprotein cholesterol levels.
More importantly, in comparison to the control group, the fed group with hypercholesterolemic also expressed lower levels in the serum and hepatic lipid peroxidation, body weight gain, and food efficiency.
Furthermore, in-support of green tea in lower levels of high blood cholesterol, Dr. Nomura S, the lead author at the NARO Institute of Vegetable and Tea Science postulated, the efficacy of green tea with significantly decreased the plasma oxidized low-density lipoprotein level in mice fed a high-cholesterol diet is depending to the flavonol-rich tea cultivars.
Taking together, green tea with tons of phytochemicals may be served as functional found with purpose in reduced risk of early onset and treatment of high blood cholesterol in the adult population.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Sources
(1) The role of green tea extract and powder in mitigating metabolic syndromes with special reference to hyperglycemia and hypercholesterolemia by Yousaf S1, Butt MS, Suleria HA, Iqbal MJ.(PubMed)
(2) Black and green tea improves lipid profile and lipid peroxidation parameters in Wistar rats fed a high-cholesterol diet by Alshatwi AA1, Al Obaaid MA, Al Sedairy SA, Ramesh E, Lei KY.(PubMed)
(3) Effects of flavonol-rich green tea cultivar (Camellia sinensis L.) on plasma oxidized LDL levels in hypercholesterolemic mice by Nomura S1, Monobe M1, Ema K1, Matsunaga A1, Maeda-Yamamoto M2, Horie H1.(PubMed)
Hypercholesterolemia is a condition of abnormally high levels of cholesterol in the bloodstream.
Green tea, a precious drink processes number of health benefits known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine, or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory.
According to the University of Agriculture, ethanolic extracts of green tea fed mice in 8 weeks in vivo model expressed significant effects in normalized levels of cholesterol in hypercholesterolemic rats up to 15.45% in comparison control.
The study also revealed that the administration of green tea does not adversely affect the red blood cell, white blood cell, and platelet count of the tested rats.
Additionally, in compared efficacy of black tea (BT) and green tea (GT) in serum and hepatic oxidative abnormalities in hypercholesterolemic rats, after 8 weeks, green and black tea fed groups displayed a significantly lower levels of serum and hepatic cholesterol, triglycerides, serum low-density lipoprotein cholesterol, and increased high-density lipoprotein cholesterol levels.
More importantly, in comparison to the control group, the fed group with hypercholesterolemic also expressed lower levels in the serum and hepatic lipid peroxidation, body weight gain, and food efficiency.
Furthermore, in-support of green tea in lower levels of high blood cholesterol, Dr. Nomura S, the lead author at the NARO Institute of Vegetable and Tea Science postulated, the efficacy of green tea with significantly decreased the plasma oxidized low-density lipoprotein level in mice fed a high-cholesterol diet is depending to the flavonol-rich tea cultivars.
Taking together, green tea with tons of phytochemicals may be served as functional found with purpose in reduced risk of early onset and treatment of high blood cholesterol in the adult population.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Sources
(1) The role of green tea extract and powder in mitigating metabolic syndromes with special reference to hyperglycemia and hypercholesterolemia by Yousaf S1, Butt MS, Suleria HA, Iqbal MJ.(PubMed)
(2) Black and green tea improves lipid profile and lipid peroxidation parameters in Wistar rats fed a high-cholesterol diet by Alshatwi AA1, Al Obaaid MA, Al Sedairy SA, Ramesh E, Lei KY.(PubMed)
(3) Effects of flavonol-rich green tea cultivar (Camellia sinensis L.) on plasma oxidized LDL levels in hypercholesterolemic mice by Nomura S1, Monobe M1, Ema K1, Matsunaga A1, Maeda-Yamamoto M2, Horie H1.(PubMed)
Saturday, October 17, 2020
Ginger Combined with Other Herbal Medicines for The Treatment of Erectile Dysfunction
Scientists may have found a natural ingredient for the treatment of erectile dysfunction with no side effects, according to studies.
Erectile dysfunction is a condition in which a man can not get or keep an erection to have sexual intercourse, affecting the self-confidence and contributing to relationship problems.
According to the statistics provided by the Massachusetts Male Aging Study, erectile dysfunction increased with age, affecting 40% and 70% of men in the age group of 40 and 70, respectively.
In other words, the prevalence of complete ED increased from 5% at age 40 to 15% at age 70. 150 million men worldwide have ED.
Age, hypertension, use of antihypertensive drugs, diabetes mellitus, heart disease, and daily stress at home, and work have been found to associate with the prevalent risk of ED.
Some researchers suggested the prevalence of ED may be correlated to widespread obesity in the Western world.
Dr. Skrypnik D, the lead scientist said, "In The United States it (obesity) causes more than 300 000 deaths per year. It leads to many complications, such as ischemic heart disease, hypertension, dyslipidemia, atherosclerosis, and abnormal carbohydrate metabolism".
And, " obesity is also an independent risk factor for erectile dysfunction in men. 79% of men presenting erectile disorders have BMI of 25 kg/m2 or greater. BMI in the range 25-30 kg/m2 is associated with 1,5 times, and in the range of over 30 kg/m2 with a 3 times greater risk of sexual dysfunction".
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
With an aim to find a natural treatment for patients with erectile dysfunction with no side effects, researchers examined the effects of oral administration of Revactin twice daily (total daily dose of 500 mg of ginger root, Muira puama, and Paullinia cupana and 1,600 mg of L-citrulline in 54 middle-aged men with erectile dysfunction.
Based on the results from the complete IIEF-15 questionnaire [domains: erectile function (EF), orgasmic function (OF), sexual desire (SD), intercourse satisfaction (IS), overall satisfaction (OS)] at baseline (B), 1 month (M1), 2 months (M2) and 3 months (M3) and report any side effects, Revactin exerted a strong effect on the increase in median domain scores of OF, SD, IS, OS over 3 months compared to baseline median scores.
However, after taking other factors into account, statistical significance was found only in the EF, IS, and OS median domain scores.
5 patients in the study showed the reporting treatment side effects (e.g., dyspepsia, heartburn, migraine) and none considered severe.
Overall, approximately 50% of the patients reported a significant improvement in EF (P<0.05), compared to baseline.
Dr. Nguyen S, the lead scientist said, "Revactin®, a combination of 3 nutraceuticals packaged with L-citrulline, appears to have the same excellent safety profile known for each of its individual four components".
Take all together, ginger combined with other herbal medicines may be considered functional alternatives for the treatment of erectile dysfunction, pending to the confirmation of large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Safety and efficacy of daily Revactin® in men with erectile dysfunction: a 3-month pilot study by Nguyen S1, Rajfer J2, Shaheen M. (PubMed)
(2) Effect of ginger, Paullinia cupana, muira puama and l- citrulline, singly or in combination, on modulation of the inducible nitric oxide- NO-cGMP pathway in rat penile smooth muscle cells by Ferrini MG1, Garcia E2, Abraham A2, Artaza JN3, Nguyen S2, Rajfer J4. (PubMed)
(3) [Obesity--significant risk factor for erectile dysfunction in men].[Article in Polish] by Skrypnik D, Bogdański P, Musialik K. (PubMed)
Erectile dysfunction is a condition in which a man can not get or keep an erection to have sexual intercourse, affecting the self-confidence and contributing to relationship problems.
According to the statistics provided by the Massachusetts Male Aging Study, erectile dysfunction increased with age, affecting 40% and 70% of men in the age group of 40 and 70, respectively.
In other words, the prevalence of complete ED increased from 5% at age 40 to 15% at age 70. 150 million men worldwide have ED.
Age, hypertension, use of antihypertensive drugs, diabetes mellitus, heart disease, and daily stress at home, and work have been found to associate with the prevalent risk of ED.
Some researchers suggested the prevalence of ED may be correlated to widespread obesity in the Western world.
Dr. Skrypnik D, the lead scientist said, "In The United States it (obesity) causes more than 300 000 deaths per year. It leads to many complications, such as ischemic heart disease, hypertension, dyslipidemia, atherosclerosis, and abnormal carbohydrate metabolism".
And, " obesity is also an independent risk factor for erectile dysfunction in men. 79% of men presenting erectile disorders have BMI of 25 kg/m2 or greater. BMI in the range 25-30 kg/m2 is associated with 1,5 times, and in the range of over 30 kg/m2 with a 3 times greater risk of sexual dysfunction".
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
With an aim to find a natural treatment for patients with erectile dysfunction with no side effects, researchers examined the effects of oral administration of Revactin twice daily (total daily dose of 500 mg of ginger root, Muira puama, and Paullinia cupana and 1,600 mg of L-citrulline in 54 middle-aged men with erectile dysfunction.
Based on the results from the complete IIEF-15 questionnaire [domains: erectile function (EF), orgasmic function (OF), sexual desire (SD), intercourse satisfaction (IS), overall satisfaction (OS)] at baseline (B), 1 month (M1), 2 months (M2) and 3 months (M3) and report any side effects, Revactin exerted a strong effect on the increase in median domain scores of OF, SD, IS, OS over 3 months compared to baseline median scores.
However, after taking other factors into account, statistical significance was found only in the EF, IS, and OS median domain scores.
5 patients in the study showed the reporting treatment side effects (e.g., dyspepsia, heartburn, migraine) and none considered severe.
Overall, approximately 50% of the patients reported a significant improvement in EF (P<0.05), compared to baseline.
Dr. Nguyen S, the lead scientist said, "Revactin®, a combination of 3 nutraceuticals packaged with L-citrulline, appears to have the same excellent safety profile known for each of its individual four components".
Take all together, ginger combined with other herbal medicines may be considered functional alternatives for the treatment of erectile dysfunction, pending to the confirmation of large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Safety and efficacy of daily Revactin® in men with erectile dysfunction: a 3-month pilot study by Nguyen S1, Rajfer J2, Shaheen M. (PubMed)
(2) Effect of ginger, Paullinia cupana, muira puama and l- citrulline, singly or in combination, on modulation of the inducible nitric oxide- NO-cGMP pathway in rat penile smooth muscle cells by Ferrini MG1, Garcia E2, Abraham A2, Artaza JN3, Nguyen S2, Rajfer J4. (PubMed)
(3) [Obesity--significant risk factor for erectile dysfunction in men].[Article in Polish] by Skrypnik D, Bogdański P, Musialik K. (PubMed)
Tuesday, October 13, 2020
Cabbage Processes Immunomodulatory Activity
The immune system is the set of cells and their activity against antigens or infectious agents that comprise the body's defense system against diseases.
The immune system does a great job of keeping people healthy and preventing infections. Besides foods and nutritional supplements, herbs also play an important role in helping the immune system defend against viruses and bacteria attacks.
Immunomodulatory activity is an action that improves the underactive immune function that is susceptible to the invasion of the foreign microorganism and inhibits the overactive immune system that causes autoimmune diseases.
In other words, the immunomodulatory activity involved antimicrobial agents is to modulate the genes involved in immune reactions, or of the neurohormonal system which regulates immune functions and any toxic or immunotoxic effects such as allergic reactions or destruction of immune effectors, that may cause harm to the body or interfere with the body normal function.
The overactive immune system is a class of autoimmune diseases or chronic inflammatory diseases caused by the immune system attacking the body's tissue, including rheumatoid arthritis (RA), rheumatoid arthritis, systemic lupus erythematosus,.... and multiple sclerosis.
The widespread chronic inflammatory diseases in modern society are a burden to humans because of life-long debilitating illness, increased mortality and high costs for therapy and care.
The underactive or weakened immune system caused by a primary immune deficiency or acquired immune deficiency.may not protect the body against foreign organisms in initiated infection.
Sometimes, temporarily weaken the immune system may also be caused by the intake of certain conventional medicine, such as chemotherapy or drugs that treat cancer.
Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem with a crowded mass of leaves, usually green but in some varieties, it may be red or purplish.
On findings a natural wholefood for the improvement of immune functioning, researchers examined the immunomodulatory effect and mechanism of Lactococcus lactis A17 (A17), isolated from Taiwan fermented cabbage, on ovalbumin (OVA)-sensitized mice.
In live (A17-A) and heat-killed A17 (A17-H) orally administered to OVA-sensitized BALB/c mice effects, researchers found that live (A17-A) and heat-killed A17 (A17-H) induced allergic effects by increasing the
* B-cell response that was modulated by diminishing IgE production and raising OVA-specific IgG2a production and the T-cell response that was modulated by increasing IFN-γ production and decreasing IL-4 production.
* Furthermore, the mRNA expression of NOD-1, NOD-2, and TLR-4 associated with the expression of inflammation and infection was down-regulated by A17.
In other words, a naïve Lactococcus lactis A17 strain exerted a significant immunomodulatory activity against allergic diseases via oral administration
Based on the results, researchers wrote, "the ameliorative effects of A17 may be caused by modulating NOD-1 NOD-2, and TLR-4 expression".
Taken altogether, cabbage processes immunomodulatory activity, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Immunomodulatory Activity of Lactococcus lactis A17 from Taiwan Fermented Cabbage in OVA-Sensitized BALB/c Mice by Mei HC1, Liu YW, Chiang YC, Chao SH, Mei NW, Liu YW, Tsai YC. (PubMed)
The immune system does a great job of keeping people healthy and preventing infections. Besides foods and nutritional supplements, herbs also play an important role in helping the immune system defend against viruses and bacteria attacks.
Immunomodulatory activity is an action that improves the underactive immune function that is susceptible to the invasion of the foreign microorganism and inhibits the overactive immune system that causes autoimmune diseases.
In other words, the immunomodulatory activity involved antimicrobial agents is to modulate the genes involved in immune reactions, or of the neurohormonal system which regulates immune functions and any toxic or immunotoxic effects such as allergic reactions or destruction of immune effectors, that may cause harm to the body or interfere with the body normal function.
The overactive immune system is a class of autoimmune diseases or chronic inflammatory diseases caused by the immune system attacking the body's tissue, including rheumatoid arthritis (RA), rheumatoid arthritis, systemic lupus erythematosus,.... and multiple sclerosis.
The widespread chronic inflammatory diseases in modern society are a burden to humans because of life-long debilitating illness, increased mortality and high costs for therapy and care.
The underactive or weakened immune system caused by a primary immune deficiency or acquired immune deficiency.may not protect the body against foreign organisms in initiated infection.
Sometimes, temporarily weaken the immune system may also be caused by the intake of certain conventional medicine, such as chemotherapy or drugs that treat cancer.
Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem with a crowded mass of leaves, usually green but in some varieties, it may be red or purplish.
On findings a natural wholefood for the improvement of immune functioning, researchers examined the immunomodulatory effect and mechanism of Lactococcus lactis A17 (A17), isolated from Taiwan fermented cabbage, on ovalbumin (OVA)-sensitized mice.
In live (A17-A) and heat-killed A17 (A17-H) orally administered to OVA-sensitized BALB/c mice effects, researchers found that live (A17-A) and heat-killed A17 (A17-H) induced allergic effects by increasing the
* B-cell response that was modulated by diminishing IgE production and raising OVA-specific IgG2a production and the T-cell response that was modulated by increasing IFN-γ production and decreasing IL-4 production.
* Furthermore, the mRNA expression of NOD-1, NOD-2, and TLR-4 associated with the expression of inflammation and infection was down-regulated by A17.
In other words, a naïve Lactococcus lactis A17 strain exerted a significant immunomodulatory activity against allergic diseases via oral administration
Based on the results, researchers wrote, "the ameliorative effects of A17 may be caused by modulating NOD-1 NOD-2, and TLR-4 expression".
Taken altogether, cabbage processes immunomodulatory activity, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
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Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Immunomodulatory Activity of Lactococcus lactis A17 from Taiwan Fermented Cabbage in OVA-Sensitized BALB/c Mice by Mei HC1, Liu YW, Chiang YC, Chao SH, Mei NW, Liu YW, Tsai YC. (PubMed)
Saturday, October 10, 2020
Green Tea, The Best Anti Metabolic Syndrome Whole Food Medicine
Green tea may be served as a functional food for reduced risk and treatment of metabolic syndrome, a renowned institute study suggested
Metabolic Syndrome is a group of risk factors used to calculate the incidence of early onset of diabetes and cardiovascular diseases.
Green tea, a precious drink processes number of health benefits known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine, or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. Adding a slice of ginger will do the trick.
In a total of 35 obese participants with metabolic syndrome randomly assigned to receive one of the following for 8 weeks: green tea (4 cups per day), control (4 cups water per day), or green tea extract (2 capsules and 4 cups water per day), blood samples collected from green tea and green tea extract-treated groups showed a significantly increased plasma antioxidant capacity (1.5 to 2.3 μmol/L and 1.2 to 2.5 μmol/L, respectively in compared to control group.
The study also found that the efficacy of green tea in ameliorated early progression of metabolic syndrome is attributed to the improved expression of serum antioxidant enzymes (glutathione peroxidase, glutathione, catalase) and plasma antioxidant capacity in inhibited free radicals in exhibition of pro-inflammatory cytokines.
Furthermore, in the total of 55 obese men and women recruited, injection of 280 and 360 g GTRB provided daily totals of 123.2 and 158.4 mg caffeine, and 188.3 and 242.1 mg of epigallocatechin gallate significantly reduced expression of metabolic syndrome in attenuated weight gain, high-density lipoprotein-cholesterol, triglycerides, and glucose concentrations.
More importantly, the study also found that administration of green tea also reduced levels of blood pressure in obese subjects but can not maintain the weight loss after study.
Other researchers in the investigation of decaffeinated green tea extract (GTE) and voluntary running exercise (Ex) alone or in combination against obesity and metabolic syndrome in high fat (HF) fed C57BL/6J mice, insisted that the combination of green tea injection and exercise treatment reduced final body mass (27.1% decrease) and total visceral fat mass (36.6% decrease), levels of fasting blood glucose (17% decrease), plasma insulin (65% decrease), and insulin resistance (65% decrease) compared to HF-fed mice.
Taking together, green tea may be one of the best candidates used for the prevention of onset and treatment of metabolic syndrome in the adult population, but the long-term injection of the large amounts may induce liver and kidney toxicity as shown in previous articles.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Green tea supplementation increases glutathione and plasma antioxidant capacity in adults with the metabolic syndrome by Basu A1, Betts NM, Mulugeta A, Tong C, Newman E, Lyons TJ.(PubMed)
(2) Effects of rye bread enriched with green tea extract on weight maintenance and the characteristics of metabolic syndrome following weight loss: a pilot study by Bajerska J1, Mildner-Szkudlarz S2, Walkowiak J1,3.(PubMed)
(4) Voluntary exercise and green tea enhance the expression of genes related to energy utilization and attenuate metabolic syndrome in high fat fed mice by Sae-Tan S1, Rogers CJ, Lambert JD.(PubMed)
Metabolic Syndrome is a group of risk factors used to calculate the incidence of early onset of diabetes and cardiovascular diseases.
Green tea, a precious drink processes number of health benefits known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine, or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. Adding a slice of ginger will do the trick.
In a total of 35 obese participants with metabolic syndrome randomly assigned to receive one of the following for 8 weeks: green tea (4 cups per day), control (4 cups water per day), or green tea extract (2 capsules and 4 cups water per day), blood samples collected from green tea and green tea extract-treated groups showed a significantly increased plasma antioxidant capacity (1.5 to 2.3 μmol/L and 1.2 to 2.5 μmol/L, respectively in compared to control group.
The study also found that the efficacy of green tea in ameliorated early progression of metabolic syndrome is attributed to the improved expression of serum antioxidant enzymes (glutathione peroxidase, glutathione, catalase) and plasma antioxidant capacity in inhibited free radicals in exhibition of pro-inflammatory cytokines.
Furthermore, in the total of 55 obese men and women recruited, injection of 280 and 360 g GTRB provided daily totals of 123.2 and 158.4 mg caffeine, and 188.3 and 242.1 mg of epigallocatechin gallate significantly reduced expression of metabolic syndrome in attenuated weight gain, high-density lipoprotein-cholesterol, triglycerides, and glucose concentrations.
More importantly, the study also found that administration of green tea also reduced levels of blood pressure in obese subjects but can not maintain the weight loss after study.
Other researchers in the investigation of decaffeinated green tea extract (GTE) and voluntary running exercise (Ex) alone or in combination against obesity and metabolic syndrome in high fat (HF) fed C57BL/6J mice, insisted that the combination of green tea injection and exercise treatment reduced final body mass (27.1% decrease) and total visceral fat mass (36.6% decrease), levels of fasting blood glucose (17% decrease), plasma insulin (65% decrease), and insulin resistance (65% decrease) compared to HF-fed mice.
Taking together, green tea may be one of the best candidates used for the prevention of onset and treatment of metabolic syndrome in the adult population, but the long-term injection of the large amounts may induce liver and kidney toxicity as shown in previous articles.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Green tea supplementation increases glutathione and plasma antioxidant capacity in adults with the metabolic syndrome by Basu A1, Betts NM, Mulugeta A, Tong C, Newman E, Lyons TJ.(PubMed)
(2) Effects of rye bread enriched with green tea extract on weight maintenance and the characteristics of metabolic syndrome following weight loss: a pilot study by Bajerska J1, Mildner-Szkudlarz S2, Walkowiak J1,3.(PubMed)
(4) Voluntary exercise and green tea enhance the expression of genes related to energy utilization and attenuate metabolic syndrome in high fat fed mice by Sae-Tan S1, Rogers CJ, Lambert JD.(PubMed)
Friday, October 9, 2020
Coffee and Coffee Caffeine in Improved Complexity of Cognitive Performance?
Epidemiological studies do not agree that regular coffee consumption may associate to improve cognitive function, a joint study lead by the Universidade Federal de Minas Gerais suggested.
Cognitive function is a cerebral activity in acquired knowledge, including all means and mechanisms of acquiring information.
Coffee, becoming a popular and social beverage all over the world, particularly in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.
In a cohort of 14,563 public service workers (35-74 years old) to examine the coffee consumption habits and cognitive function using a standardized neuropsychological test, researchers at the above institutes filed the following results
1. Elderly drinking 2-3 cups/day, showed a significant improvement in the mean words remembered on learning, recall, and word recognition in comparison to never/almost never groups.
2. And those drinking more than 3 cups a day exhibited increased mean words pronounced, according to the semantic verbal fluency test in comparison to the same groups.
Dr. Araújo LF, the lead author said, "coffee consumption might be slightly beneficial to memory in elderly but lacks a dose-response relationship".
Further more, in 2,914 participants from the population-based Rotterdam Study (mean age: 59.3±7.2 years, 55% females) to assess coffee consumption, performed brain MRI, and cognition at baseline, researchers found that
1. Higher coffee consumption showed a lower prevalence of lacunar infarcts [odds ratio per cup increase: 0.88 (95% CI:0.79;0.98)]involved development of stroke, and smaller hippocampal volume in the expression of memory ability.
2. Coffee consumption promoted better performance on the Letter Digit Substitution Task
3. But do not improve on the 15-Word Learning test delayed recall.
Dr. Araújo LF, again said, "...(there is a) complex associations between coffee consumption, brain structure, and cognition. Higher coffee consumption was cross-sectionally associated with a lower occurrence of lacunar infarcts and better executive function.
Interestingly, according to the study of coffee consumption and other baseline variables of 2606 middle-aged Finnish twins assessed in 1975 and 1981 by postal questionnaires, with after the median follow-up of 28 y, coffee consumption was not an independent predictor of cognitive performance in old age, according to the linear regression analysis.
The study also insisted that coffee drinking did not affect the risk of mild cognitive impairment or dementia, but expressed an inconsistent cognitive score.
Taking all together, coffee and coffee caffeine can only improve the performance of some cognitive function but not as a whole, particularly in the older population.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Inconsistency of Association between Coffee Consumption and Cognitive Function in Adults and Elderly in a Cross-Sectional Study (ELSA-Brasil) by Araújo LF1, Giatti L2, Reis RC3, Goulart AC4, Schmidt MI5, Duncan BB6, Ikram MA7, Barreto SM8.(PubMed)
(2) Association of Coffee Consumption with MRI Markers and Cognitive Function: A Population-Based Study by Araújo LF1,2, Mirza SS2, Bos D2,3, Niessen WJ3,4, Barreto SM1, van der Lugt A3, Vernooij MW2,3, Hofman A2, Tiemeier H2,5,6, Ikram MA2,3,(PubMed)
(3) Coffee drinking in middle age is not associated with cognitive performance in old age by Laitala VS1, Kaprio J, Koskenvuo M, Räihä I, Rinne JO, Silventoinen K.(PubMed)
Cognitive function is a cerebral activity in acquired knowledge, including all means and mechanisms of acquiring information.
Coffee, becoming a popular and social beverage all over the world, particularly in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.
In a cohort of 14,563 public service workers (35-74 years old) to examine the coffee consumption habits and cognitive function using a standardized neuropsychological test, researchers at the above institutes filed the following results
1. Elderly drinking 2-3 cups/day, showed a significant improvement in the mean words remembered on learning, recall, and word recognition in comparison to never/almost never groups.
2. And those drinking more than 3 cups a day exhibited increased mean words pronounced, according to the semantic verbal fluency test in comparison to the same groups.
Dr. Araújo LF, the lead author said, "coffee consumption might be slightly beneficial to memory in elderly but lacks a dose-response relationship".
Further more, in 2,914 participants from the population-based Rotterdam Study (mean age: 59.3±7.2 years, 55% females) to assess coffee consumption, performed brain MRI, and cognition at baseline, researchers found that
1. Higher coffee consumption showed a lower prevalence of lacunar infarcts [odds ratio per cup increase: 0.88 (95% CI:0.79;0.98)]involved development of stroke, and smaller hippocampal volume in the expression of memory ability.
2. Coffee consumption promoted better performance on the Letter Digit Substitution Task
3. But do not improve on the 15-Word Learning test delayed recall.
Dr. Araújo LF, again said, "...(there is a) complex associations between coffee consumption, brain structure, and cognition. Higher coffee consumption was cross-sectionally associated with a lower occurrence of lacunar infarcts and better executive function.
Interestingly, according to the study of coffee consumption and other baseline variables of 2606 middle-aged Finnish twins assessed in 1975 and 1981 by postal questionnaires, with after the median follow-up of 28 y, coffee consumption was not an independent predictor of cognitive performance in old age, according to the linear regression analysis.
The study also insisted that coffee drinking did not affect the risk of mild cognitive impairment or dementia, but expressed an inconsistent cognitive score.
Taking all together, coffee and coffee caffeine can only improve the performance of some cognitive function but not as a whole, particularly in the older population.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Inconsistency of Association between Coffee Consumption and Cognitive Function in Adults and Elderly in a Cross-Sectional Study (ELSA-Brasil) by Araújo LF1, Giatti L2, Reis RC3, Goulart AC4, Schmidt MI5, Duncan BB6, Ikram MA7, Barreto SM8.(PubMed)
(2) Association of Coffee Consumption with MRI Markers and Cognitive Function: A Population-Based Study by Araújo LF1,2, Mirza SS2, Bos D2,3, Niessen WJ3,4, Barreto SM1, van der Lugt A3, Vernooij MW2,3, Hofman A2, Tiemeier H2,5,6, Ikram MA2,3,(PubMed)
(3) Coffee drinking in middle age is not associated with cognitive performance in old age by Laitala VS1, Kaprio J, Koskenvuo M, Räihä I, Rinne JO, Silventoinen K.(PubMed)
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