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Tuesday, January 10, 2023

Honey, the Best Natural Remedy for Chronic Otitis Externa With No Side Effects

In seeking natural therapy with no side effects, scientists may have found a herbal medicine for the prevention and treatment of acute otitis externa, according to studies.

Acute otitis externa is a condition characterized by the inflammation of the ear canal. Most cases of acute acute otitis externa are associated with the infection by Pseudomonas aeruginosa and Staphylococcus aureus due to improper cleaning.

However, people with seborrhoeic dermatitis caused by inflammation of greasy areas of the skin can also lead to infection of the ears.

The most common symptoms of acute otitis include itching, canal edema, canal erythema, and otorrhea.

Most cases of acute otitis externa are healed within days with proper ear drops. However, there is a rare case that the disease may take weeks or months to recover.


Chronic otitis externa shares the common symptoms of the acute form, accompanied by water retention and severe ear pain, and temporary loss of hearing, due to building up thick and dry skin can build up inside the ear canal, leading to narrowing the ear canal.

Untreated chronic otitis externa can cause deafness.

Besides sharing the risk factors with the acute form, otitis externa can also be caused by infection due to the long-term use of hearing aids and earplugs.


Unlike the acute form, most cases of otitis externa are treated with steroid drops in addition to antibiotics accompanied by oral intake of pain medications such as ibuprofen.


Generally, oral antibiotics are not recommended, however, if the infection has spread beyond the ear canal, oral antibiotics may be applied.


According to the statistics, otitis externa affects 1–3% of people in America a year and 95% of people's complaints of the condition are acute.


Honey, the rich golden liquid is a miraculous product made by bees using nectar from flowers.

The liquid is considered healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.

On finding a natural ingredient for the treatment of eczematous external otitis, scientists investigated the antibacterial potential of medical honey eardrops treatment of eczematous external otitis.


15 patients diagnosed with recurrent eczematous external otitis were selected and treated with medical honey eardrops for 2 weeks.

Honey treatment resulted in less discomfort and itching and decreased signs of eczema with no side effects, according to assays.


Although honey eardrops showed a strong in vitro inhibitory activity against all tested strains, they did not eradicate Staphylococcus aureus infection.


Honey eardrops also reduced the visual analog scale of ear complaints, and a score of eczema, and increased the eradication of bacterial infection. Most patients in the study, are satisfied with the use of honey eardrops for the treatment of their eczematous external otitis.


Dr. Henatsch D, the lead scientist, after taking into account co and confounders said, "The results of this preliminary study indicate a possible role of honey eardrops in eczematous ear disease".

Taken altogether, honey may be considered a functional remedy for the treatment of eczematous external otitis, pending the confirmation of a larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Treatment of Recurrent Eczematous External Otitis with Honey Eardrops: A Proof-of-Concept Study by Henatsch D1, Nabuurs CH1, van de Goor RM1, Wolffs PF2, Stokroos RJ. (PubMed)
(2) Alternative Treatments for Atopic Dermatitis: An Update by Shi K1, Lio PA. (PubMed)
(2) Acute Otitis Externa: An Update by PAUL SCHAEFER, MD, PhD, and REGINALD F. BAUGH, MD. (AAFP)

Saturday, December 3, 2022

The Possible Effects of Healthy Veggie Broccoli on Hypertension, Researchers Say

Blood pressure is the force of the blood pushing against the arterial walls. In high blood pressure, the heart has to work harder than normal to pump blood through the circulation system. Over time, high blood pressure has been found to cause damage to the heart and arteries.

Hypertension or high blood pressure is a condition characterized by persistent high blood pressure.

In the US approximately, one-third of adults have high blood pressure, affecting over 77 million people in the country.

Additionally, among adults aged 20 and older in the United States, in the non-Hispanic whites community, 33.4 percent of men and 30.7 percent of women are infected by the syndrome.

High blood pressure is a slowly developed condition. Unless the syndrome has caused damage to the blood vessel, otherwise symptoms cannot be detected.


High blood pressure is a chronic condition associated with an unhealthy lifestyle and chronic diseases such as kidney disease, leading to the onset of strokes and cardiovascular disease.

In other words, if you can control your diet, such as making changes to your lifestyle, maintaining an ideal weight, and dieting with low salt, you could do just fine without the drugs.

The cause of high blood pressure is a result hardening and thickening of the arteries (atherosclerosis), due to the slow progression of plaques accumulated on the wall of the arteries.


According to the American Heart Association (AHA) patients with blood pressure that is higher than 130 over 80 millimeters of mercury (mmHg) is considered to have hypertension.

Untreated chronic high blood pressure may induce complications of heart attack, stroke, and other health conditions.


Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae. The vegetable has large flower heads, usually green in color and the mass of flower heads is surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.


In finding a potential plant that processes anti-high blood pressure, researchers examined the broccoli protein hydrolysates' inhibitory activity in vitro and hypotensive effect in vivo.


According to the results of the analysis,
* Three ACE inhibitory peptides were isolated and identified as IPPAYTK, LVLPGELAK, and TFQGPPHGIQVER, and their inhibitory IC50 values were 23.5, 184.0, and 3.4 μM, respectively.


* LVLPGE and LAK, two novel peptides exhibited the highest ACE inhibitory activity associated with lowering hypertension with IC50 values of 13.5 and 48.0 μM, respectively.


* Moreover, the hypotensive effect of the peptides was assessed after oral administration to spontaneous hypertensive rats (SHRs).


Collectively, researchers said, "LVLPGE and LAK demonstrated a significant hypotensive effect in vivo. Protein from broccoli may thus constitute a potential antihypertensive peptide source".


Taken altogether, broccoli may be considered a functional food for the prevention and treatment of hypertension, pending the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca



Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources

(1) In Vitro and in Vivo Studies on the Angiotensin-Converting Enzyme Inhibitory Activity Peptides Isolated from Broccoli Protein Hydrolysate by Dang Y1, Zhou T2, Hao L1, Cao J1, Sun Y1, Pan D. (PubMed)

Sunday, November 27, 2022

#Healthyfood Red Cabbage Processes Anti-Bacteria Infection, Researchers Say

Infectious diseases are medical conditions caused by pathogenic microorganisms, including bacteria, viruses, parasites, or fungi.
Most cases of infectious diseases are contagious by spreading directly or indirectly, from one person to another.

In other words, if you kiss, or are coughed or sneezed on by an infectious person, you are at risk of developing the same infectious disease.

According to the statistic provided by the World Health Organization, 3 infectious diseases were ranked in the top ten causes of death worldwide in 2016.

More precisely, lower respiratory infections, diarrheal diseases, and tuberculosis induced 3.0 million, 1.4 million, and 1.3 million deaths, respectively.

Conventionally, most cases of infectious diseases except those caused by viruses are treated with antibiotics.

Bacteria is a type of biological cell consisting of a single cell with a simple internal structure.

The most common diseases caused by bacteria include strep throat, urinary tract infections, and tuberculosis.

Infection occurs when the bacteria successfully invade the body and start to multiply. Most cases of infectious diseases caused by bacteria are treated with antibiotics.

And, most cases of infectious disease are transmitted by airborne you can get sick if you breathe into the air that carries infectious bacteria in air particles, vector-borne if you are stunk by the insect that the bacteria, and vehicle-borne if you are eating food or carrying the materials contaminated by the bacteria.

Most cases of bacterial invasion are met with the first line of immune white blood cells. In the active division of bacteria in the acute phase of infection, the immune system response activated the production of the proinflammatory cytokine to the site of infection with an aim to kill off all bacteria.

However, if the immune fails to kill off all the bacteria within the 3 - 8 weeks period, it then will adapt to the change, leading to chronic inflammatory and infectious diseases.

Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem with a crowded mass of leaves, usually green but in some varieties, it may be red or purplish.

To find a natural wholefood for the prevention of infectious disease, researchers examined the B. oleracea L (red cabbage) anti-microbial activity.

In 22 pathogenic bacteria and fungi, B. oleracea L (red cabbage) demonstrated antibacterial (Methicillin-resistant Staphylococcus aureus, Escherichia coli O157: H7, Pseudomonas aeruginosa, Klebsiella pneumonia, Staphylococcus aureus, and Salmonella enterica serovar Typhimurium) and antifungal (Trichophyton rubrum and Aspergillus terreus) activities at a minimum bactericidal concentration (MBC) and the minimum fungicidal concentration (MFC), respectively.


In Chemical analysis, the potent antimicrobial action from B. oleracea L (red cabbage) was attributed to the rich source of phenolic compounds, anthocyanins.

Based on the results, researchers wrote, "This extract is potentially novel for future antimicrobials, inexpensive, and readily available at a large scale for pharmaceutical companies for further investigation and processing".

Taken altogether, red cabbage may be considered a natural antibiotic, pending the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional's Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Inhibition of Growth of Highly Resistant Bacterial and Fungal Pathogens by a Natural Product by Rand R Hafidh,1,2 Ahmed S Abdulamir,2,3 Law Se Vern,4 Fatimah Abu Bakar,4,* Faridah Abas,4 Fatemeh Jahanshiri,5 and Zamberi Sekawi. (PMC)

Tuesday, November 22, 2022

#Healthy #Tomato/Lycopene the Anti Cancers Functional Food


Cancers are a class of diseases caused by irregular cell growth in the tissue or organ in the body.

According to the Canadian Cancer Society, in 2017, over 200,000 new cases of cancer were diagnosed and 80,800 patients died from the disease in the same year.

Lung, colorectal, breast, and prostate cancer accounted for about half of all cancer diagnoses and deaths.
Believe it or not, 1 in 2 Canadian adults will develop cancer in their lifetimes and 1 in 4 will die of the disease.


At the early stage, patients with cancer may not experience any symptoms due to the very small size of the tumor and the cancer is still on the surface in the inner lining tissues. However, at the late stage after colonizing the complete organ, cancer cells not can travel a distance away from the originated site to affect other healthy tissue and organ, they can also cause some related and specific symptoms accompanied by general symptoms associated with other types of cancer.


Cancer is classified by the followings* Size of the cancer

* Invasive or not

* Whether cancer has spread to the lymph nodes

* Whether cancer has spread to distant parts or organs of the body.

There are 4 stages of breast cancer in TNM rating (where T is referred for tumor size, N is referred for Lymph Node status, and M is referred for invasive or not)

Where
# T: Tumor Size is divided into four classes: T-1 is between 0 - 2 cms, T-2 is between 2 - 5 cms, T-3 is > 5cms, and T-4 is a tumor of any size growing into the chest wall or skin, including inflammatory breast cancer.
#N: No swollen nodes: N-0, some swelling but negative node (not cancerous): N-1a, swelling nodes and positive node (cancerous): N-1b, quite swollen and bunched together: N-2, quite swollen and near the collarbone: N-3.
# M: if no cancer cell is found: M-0, cancer cells found: M-1.

The stages of cancer are
* Stage 1T-1 tumor and clear lymph nodes with no evidence of spreading (M-0), or T-1N-0M-0.
* Stage 2
Stage 2 is the combination of a combination of T-1, T-2, or T-3 tumor, N-0. N-1a and N-1b but no spreading (M-0)
* Stage 3
Stage 3 is the combination of all T or N but no spreading (M-0)
* Stage 4
Stage 4 is the combination of T, N-1a, N-1b, N-2, N-3, and M-1


Tomato is red, edible fruit, genus Solanum, belonging to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.

In the urgency to find a potential ingredient for the treatment of cancer with little or no side effect, researchers examined the effect of a novel strategy of formulating the lycopene-loaded whey protein isolate nanoparticles (LYC-WPI-NPs) ability for adenosine deaminase inhibition of the regression of the tumor with the percent lycopene entrapment in the range to 50 and 65%.

In the chemical release analysis, LYC-WPI-NPs enhanced the oral bioavailability of lycopene by controlling its release through the absorption in the lymphatic pathways.

According to the MTT-based colorimetric assay, LYC-WPI-NPs exerted significant cytotoxicity against MCF-7 breast cancer cells in vitro.

In an animal model-induced breast cancer, LYC-WPI-NPsd also demonstrated its prophylactic anticancer efficacy without causing the death of normal cells.

Based on the findings, researchers wrote in the final paper, "Conclusively, it may quite reasonable that lycopene loaded protein nanoparticles are competent to improve the biopharmaceutical attributes of lycopene and demonstrated prophylactic anticancer activity, decrease tumor proliferation and increase the survival rate of treated animals".


In other words, LYC-WPI-NPs significantly enhanced the lycopene anti-cancer biopharmaceutic activity compared to oral administration as seen in an animal model.

Taken altogether, tomatoes may be considered supplements for the prevention and treatment of cancer, pending the confirmation of the larger sample size and multicenter human study.

Intake of lycopene in the form of a supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Tomato (Solanum lycopersicum) Carotenoids and Lycopenes Chemistry; Metabolism, Absorption, Nutrition, and Allied Health Claims--A Comprehensive Review by Perveen R1, Suleria HA, Anjum FM, Butt MS, Pasha I, Ahmad S. (PubMed)
(2) Lycopene loaded whey protein isolate nanoparticles: An innovative endeavor for enhanced bioavailability of lycopene and anti-cancer activity by Jain A1, Sharma G2, Ghoshal G3, Kesharwani P4, Singh B5, Shivhare US4, Katare OP. (PubMed)

Saturday, October 22, 2022

Healthy Food Potatoes (Solanum), Process a Strong Antioxidant Property

Antioxidants are stable atom that plays a critical role in protecting the body against the attack of free radicals.

In other words, antioxidants inhibited the onset of free radicals before they can cause a chain reaction in facilitating oxidative stress that causes damage to proteins, lipids, and cell DNA.

Oxidative stress is a result of an imbalance in the ratio of free radicals and antioxidants in the body.

Free radicals are highly reactive molecules with an unpaired electron on the outer ring of the atom.

Due to their nature to become stable, free radicals readily donate or steal an electron from other molecules, leading to the chain of domino effect that can not be stopped until either the electrons are paired or inhibited by antioxidants.

This chain of reaction is the cause of oxidative stress, a condition associated with either overexpression of free radicals or depletion of antioxidant enzymes produced by the host organs.

Overexpression of free radicals is known to cause damage in contributing to the etiology of many chronic health problems such as cardiovascular and inflammatory disease, cataracts, and cancer.
Antioxidants, on the other hand, are stable molecules with a unique function in the inhibition of oxidation.

Antioxidants can either be produced by the liver or intake from dietary sources. Under normal conditions, antioxidant enzymes produced by the body in a healthy individual are good enough to counter the bombardment of free radical attacks.

However, in people with a weakened immune system, intake of dietary sources of antioxidants may be necessary.

There are 3 main types of antioxidants found in nature, including antioxidant enzymes produced by the host, including superoxide dismutase (SOD), glutathione peroxidase, glutathione reductase, and catalases, antioxidants vitamins, that may be injected from dietary sources such as fruits and vegetables, including vitamins A, C, D, and E and antioxidant-phytochemicals found in the plant including second metabolites.

Potato is the genus Solanum and belongs to the family Solanaceae. It is a good source of protein and according to the statistic, the annual diet of an average global citizen is about 33 kg (72.6 Lbs) of potato. The root veggie now is growing worldwide in a suitable climate for commercial profits and health benefits, thus its consumption is extremely variable and rapidly changing.

In finding a potential plant for the prevention and treatment of diseases associated with oxidative stress, researchers examined the potential of peptide fractions isolated from dehydrated potatoes on intestinal epithelial cells (IEC-6) under oxidative and inflammatory conditions.

Based on the results of differentiation,* Peptide fractions demonstrated a significantly inhibit the pro-inflammatory protein expression such as tumor necrosis factor-α and cycloxygenase-2 and inducible nitric oxide synthase.

* More importantly, the tested peptides also showed significant antioxidant activity by reducing reactive oxygen species (ROS) release induced from mitochondria, and nitrotyrosine formation

* Furthermore, the applications also increase the antioxidant response by heme oxygenase-1 and superoxide dismutase expression.

Additionally, the peptide fractions were able to significantly increase wound repair in IEC-6 induced by oxidative-inflammatory damage.

Collectively, researchers said, "The obtained results indicate the anti-inflammatory and antioxidant potential of dehydrated potatoes at the intestinal level".


Taken altogether, potatoes may be considered a functional food for the prevention and treatment of diseases associated with oxidative stress, pending the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca



Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Anti-Inflammatory and Antioxidant Properties of Dehydrated Potato-Derived Bioactive Compounds in Intestinal Cells by Basilicata MG1,2, Pepe G1, Rapa SF1, Merciai F1,2, Ostacolo C3, Manfra M4, Di Sarno V1, Autore G1, De Vita D5, Marzocco S1, Campiglia P. (PubMed)

Friday, October 7, 2022

The Possible Effects of Healthy Veggie Broccoli on Hypertension

Blood pressure is the force of the blood pushing against the arterial walls. In high blood pressure, the heart has to work harder than normal to pump blood through the circulation system. Over time, high blood pressure has been found to cause damage to the heart and arteries.

Hypertension or high blood pressure is a condition characterized by persistent high blood pressure.

In the US approximately, one-third of adults have high blood pressure, affecting over 77 million people in the country.

Additionally, among adults aged 20 and older in the United States, in the non-Hispanic whites community, 33.4 percent of men and 30.7 percent of women are infected by the syndrome.

High blood pressure is a slowly developed condition. Unless the syndrome has caused damage to the blood vessel, otherwise symptoms cannot be detected.

High blood pressure is a chronic condition associated with an unhealthy lifestyle and chronic diseases such as kidney disease, leading to the onset of strokes and cardiovascular disease.

In other words, if you can control your diet, such as making changes to your lifestyle, maintaining an ideal weight, and dieting with low salt, you could do just fine without the drugs.

The cause of high blood pressure is a result hardening and thickening of the arteries (atherosclerosis), due to the slow progression of plaques accumulated on the wall of the arteries.


According to the American Heart Association (AHA) patients with blood pressure that is higher than 130 over 80 millimeters of mercury (mmHg) are considered to have hypertension.

Untreated chronic high blood pressure may induce complications of heart attack, stroke, and other health conditions.


Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae. The vegetable has large flower heads, usually green in color and the mass of flower heads is surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.


In finding a potential plant that processes anti-high blood pressure, researchers examined the broccoli protein hydrolysates' inhibitory activity in vitro and hypotensive effect in vivo.


According to the results of the analysis,
* Three ACE inhibitory peptides were isolated and identified as IPPAYTK, LVLPGELAK, and TFQGPPHGIQVER, and their inhibitory IC50 values were 23.5, 184.0, and 3.4 μM, respectively.

* LVLPGE and LAK, two novel peptides exhibited the highest ACE inhibitory activity associated with lowering hypertension with IC50 values of 13.5 and 48.0 μM, respectively.

* Moreover, the hypotensive effect of the peptides was assessed after oral administration to spontaneous hypertensive rats (SHRs).

Collectively, researchers said, "LVLPGE and LAK demonstrated a significant hypotensive effect in vivo. Protein from broccoli may thus constitute a potential antihypertensive peptide source".


Taken altogether, broccoli may be considered a functional food for the prevention and treatment of hypertension, pending the confirmation of the larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professional's Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca



Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) In Vitro and in Vivo Studies on the Angiotensin-Converting Enzyme Inhibitory Activity Peptides Isolated from Broccoli Protein Hydrolysate by Dang Y1, Zhou T2, Hao L1, Cao J1, Sun Y1, Pan D. (PubMed)

Saturday, October 1, 2022

Cabbage Protects the Cell's Integrity Against Oxidative Stress

Oxidative stress is a condition caused by an imbalance of the ratio of free radicals and antioxidants in the body.
In other words, oxidative stress is either caused by overexpression of free radicals or depletion of antioxidant enzymes in the body.

Some researchers suggested that oxidative stress may also arise due to the chain reaction of free radicals in which free radicals donate or intercept an electron from other stable molecules.

Long-term oxidative stress present in the body can cause protein and lipid damage and alternation of cell DNA, leading to the onset of chronic diseases, including cardiovascular disease, diabetes, and cancer.

More precisely, exogenous factors, such as cigarette smoke, and endogenous factors, such as the oxidative burst from activated macrophages are some of the factors involved in the risk of oxidative stress.

Free radicals are highly reactive molecules with an unpaired electron on the outer ring of the atom.

Due to its nature to become stable, free radicals readily donate or steal an electron from other molecules, leading to the chain of domino effect that can not be stopped until either the electrons are paired or inhibited by antioxidants.
This chain of reaction is the cause of oxidative stress, a condition associated with either overexpression of free radicals or depletion of antioxidant enzymes produced by the host organs.

Antioxidants are stable atom that plays a critical role in protecting the body against the attack of free radicals.

In other words, antioxidants inhibited the onset of free radicals before they can cause a chain reaction in facilitating protein, lipid, and cell damage.

Antioxidants can either be produced by the liver or intake from dietary sources. Under normal conditions, antioxidant enzymes produced by the body in a healthy individual are good enough to counter the bombardment of free radical attacks.


Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem with a crowded mass of leaves, usually green but in some varieties, it may be red or purplish.

On findings of a natural whole for the prevention and treatment of diseases associated with oxidative stress, researchers investigated the effects of red cabbage anthocyanin (RCA)-enriched extract on H₂O₂ expression on HepG2 cells.

According to chemical analysis, all derivatives of cyanidin (268 ± 2 μg/mg) found in RCA, mainly with 19% nonacylated, 51% monoacylated, and 31% diacylated structures with ferulic, sinapic, p-coumaric, and caffeic acids exerted antioxidant activity against the oxidative stress induced by the injection of H₂O₂.

Furthermore, the application of RCA extracts markedly ameliorated cell apoptosis and improved viability.

Moreover, in another study, cabbage extract protected against H2O2-induced cell death and did not elicit any cytotoxic effects by suppressing ROS production and increasing the expression of antioxidant proteins (SOD-1, catalase, and GPx) produced by the host.


In oxidative stress-exposed H9c2 cells, the protective effects of cabbage extract also inhibited apoptotic responses and activation of MAPK proteins (ERK1/2, JNK, and p-38) involved in the resistance of apoptosis by preserving mitochondrial functions.

Based on the results, researchers wrote, "cabbage extract protects against oxidative stress and suggests that it can be used as an alternative therapeutic strategy to prevent the oxidative stress in the heart".

Taken altogether, cabbage may be used as a functional food for the prevention and treatment of diseases associated with oxidative stress, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals' Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca



Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Characterization of Purified Red Cabbage Anthocyanins: Improvement in HPLC Separation and Protective Effect against H₂O₂-Induced Oxidative Stress in HepG2 Cells by Fang S1, Lin F2, Qu D3, Liang X4, Wang L. (PubMed)
(2) Cabbage (Brassica oleracea var. capitata) Protects against H2O2-Induced Oxidative Stress by Preventing Mitochondrial Dysfunction in H9c2 Cardiomyoblasts by Yang DK. (PubMed)