Tualang Honey Shows a Strong effect in Boosting Memory in Vivo, Researchers Say

Honey may have a profound and positive effect in boosting human memory, some scientists suggested

Memory is a process of the minds in learning and storing information.

Memory impairment is a condition of not remembering the new and current event which may be recalled in a short period of time, affecting mostly the older population.

Memory impairment is an early symptom associated with late-life neurodegenerative diseases.

In contrast to general belief, memory impairment not only is associated with the progression of neurodegenerative diseases but also can be caused by other factors such as medical conditions including stroke and brain injury.

Long-term use of certain medications such as antidepressants, antihistamines, anti-anxiety medications, excessive alcohol drinking, substance abuse, and tobacco are some major risk factors associated with the onset of memory loss.

Some researchers suggested that people who are living under long-term stress and anxiety or follow a nutritionally deficient diet are most vulnerable to the condition develops.

According to the article "Stress might lead to memory loss and brain shrinkage, study says" By Sandee LaMotte, CNN wrote, "If you live a high-stress life, you could have memory loss and brain shrinkage before you turn 50, according to a study published Wednesday in the journal Neurology".

"Higher levels of cortisol, a stress hormone, seem to predict brain function, brain size and performance on cognitive tests," said study author Dr. Sudha Seshadri, professor of neurology at UT Health San Antonio.

"We found memory loss and brain shrinkage in relatively young people long before any symptoms could be seen," Seshadri said. "It's never too early to be mindful of reducing stress."


In other words, long-term stress can induce the production of certain hormones such as cortisol which have strong implications on the brain in the induction of memory loss.

Honey is a miraculous product made by bees using nectar from flowers.

The rich golden liquid It is considered one of healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.

On finding the correlation and association with the aging and stress exposure and memory impairment, researchers examined the potential protective effects of Tualang honey supplementation on memory performance in aged rats exposed to noise stress.

Tested rats were given orally, 200 mg/kg body weight of Tualang honey supplementation for 28 days, before exposing to the loud noise, 100 dB(A), 4 hours daily for 14 days.

Rats subjected to noise stress exhibited significantly lower memory performance and higher oxidative stress, through the increased expression of oxidative stress markers, the elevated malondialdehyde, and protein carbonyl levels.

The stress rats also exhibited a reduction of the levels of antioxidant enzymes compared to the nonstressed rats.

Tualang honey supplementation applied to the stress rats showed a significant improvement of the memory performance, by decreasing oxidative stress levels and increasing the brain-derived neurotrophic factor (BDNF) concentration, which was reduced due to stress.

Furthermore, Tualang honey also normalized the ratio of free radicals and antioxidants in the stress rats body and enhanced neuronal proliferation in the medial prefrontal cortex (mPFC) and hippocampus associated with memory, particularly, in long-term memory.

Dr. Azman KF, the lead scientist at the final report wrote, "Tualang honey protects against memory decline due to stress exposure and/or aging via enhancement of mPFC and hippocampal morphology possibly secondary to a reduction in brain oxidative stress and/or upregulation of BDNF concentration and cholinergic system".

The results underlined the effects of Tualang honey effect in boosting short and long-term memory which was significantly reduced by stress exposure and/or aging.

Moreover, in the study of the total of forty-eight adult male rats randomly divided into the following four groups: i) nonstressed with vehicle, ii) nonstressed with Tualang honey, iii) stressed with vehicle, and iv) stressed with honey with supplement was given once daily via oral gavage at 0.2 g/kg body weight, researchers found that
* The rats subjected to noise stress were found to process higher levels of depressive-like behavior and lower memory functions compared to the unexposed control rats.

* Tuatang honey supplementation regimen successfully counteracted the effects of noise stress.

* Tualng honey also increased the climbing and swimming and mobility times significantly.

These results suggested that Tualang honey normalizes the cognitive function of the rats exposed to noise stress, similar to those of the first study.

Taken altogether, Tualang honey may be considered a functional food for the prevention and combined with the primary therapy for the treatment of cognitive impairment, pending the larger and multicenter's human study.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.

Sources
(1) Tualang Honey Attenuates Noise Stress-Induced Memory Deficits in Aged Rats by Azman KF1, Zakaria R1, Abdul Aziz CB1, Othman Z2. (PubMed)
(2) Tualang honey improves memory performance and decreases depressive-like behavior in rats exposed to loud noise stress by Azman KF1, Zakaria R, AbdAziz C, Othman Z, Al-Rahbi B. (PubMed)
(3) Potential Role of Honey in Learning and Memory by Othman Z1, Zakaria R2, Hussain NHN3, Hassan A4, Shafin N5, Al-Rahbi B6, Ahmad AH. (PubMed)