Epidemiological studies do not agree that maternal Caffeine Intake during pregnancy may have a negative impact on child cognition and behavior, a new study suggested.
Coffee, second to green tea is a popular and social beverage all over the world, particular in the West, made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.
Cognition and Behavior is a group of neuron functions involving sensation and perception, learning and memory, attention, mental imagery, conceptual presentation, language expression, emotion response, motor control,.....
In the study of examining maternal serum paraxanthine at <20 and ≥26 weeks gestation with the child's intelligence quotient (IQ) and problem behaviors at ages 4 and 7 years among 2,197 mother-child pairs, researchers showed that paraxanthine, a structurally related to caffeine.and caffeine's primary metabolite concentration has a significantly inverted effect at ≥26 weeks gestation with child's IQ at age 7 years.
And at <20 weeks, paraxanthine also expressed a linearly associated with internalizing behavior at age 4 years.
Interestingly, after taking into account a range of values applicable to most pregnant women, researchers indicated that coffee caffeine in contribution to serum paraxanthine concentration showed no significant effect in association with childhood IQ or problem behaviors.
In contrast to the healthy mothers, Women's reported coffee intake per day during pregnancy was associated with lower child's Behavior Rating Scale (BRS), a complete overview of child and adolescent concerns and disorders, ratings in anemic children. Even with the inclusion of other contributing factors and after anemic children given appropriate treatment, coffee consumption continuously showed Poor Child Cognition and Behavior.
Dr.Engle PL, the lead author said, " The effects of postnatal coffee ingestion in Guatemala were seen for sleep duration, but not for cognitive development. Prenatal coffee ingestion was negatively associated with Behavior Rating Scales".
Taking all together, coffee caffeine intake during pregnancy may not have any meaningful effect in association to childhood cognitive development and measurement of Behavior Rating Scales, excluding anemic children,
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Maternal Caffeine Intake During Pregnancy and Child Cognition and Behavior at 4 and 7 Years of Age by Klebanoff MA, Keim SA.(PubMed)
(2) Effects of discontinuing coffee intake on iron deficient Guatemalan toddlers' cognitive development and sleep by Engle PL1, VasDias T, Howard I, Romero-Abal ME, Quan de Serrano J, Bulux J, Solomons NW, Dewey KG.(PubMed)
Get Pregnant Naturally
".....Utilizing Traditional Chinese Medicine in Tonifying Energy flow to the Reproductive System Channels In Men and Women for Natural Conception, including Couple Who were diagnosed with Unexplained causes of Infertility...." Chantel M.
Thursday, March 11, 2021
Sunday, March 7, 2021
Localized Honey, the Best for the Treatment of Allergies with No Side Effects, According to Studies
Scientists may have found a natural alternative for the treatment of allergies, according to studies.
Allergies are a faulty reaction of the immune system responses against harmful substances that enter the body.
Symptoms and diseases associated with allergy include sinus swelling, seasonal and returning allergies, hay fever, and nasal allergies.
Believe it or not, Penicillin, antibiotic medicine is the most common allergy trigger in drug allergies. 10 percent of people are allergic after using the medicine.
According to the statistics, in the US, approximately, more than 50 million Americans have experienced various types of allergies each year and 15 million Americans have food allergies, including 5.9 million children under age 18.
In other words, 1 in 13 children suffers from a food allergy. About 30 percent of children with food allergies are allergic to more than one food.
The findings strongly suggested that foods are the most common and major cause of allergic onset.
Dr. Ruchi S. Gupta and colleagues in the allergic team in examining the food allergies in children wrote, "Overall, estimated current FA prevalence was 7.6%,.The most prevalent allergens were peanut (2.2%), milk (1.9%), shellfish (1.3%), and tree nut (1.2%)".
And, "Among food-allergic children, 42.3% reported ≥1 severe FA and 39.9% reported multiple FA. Furthermore, 19.0% reported ≥1 FA-related emergency department visit in the previous year and 42.0% reported ≥1-lifetime FA-related emergency department visit, whereas 40.7% had a current epinephrine autoinjector prescription.
Honey is a miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered one of the healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.
Researchers on finding a natural compound for the treatment of allergies examined the honey effects in the treatment of allergic rhinitis (AR).
The prospective randomized placebo-controlled study included 40 AR patients divided equally into a case group and a control group. All the subjects received a daily dose of 10 mg of loratadine for 4 weeks.
The case group then ingested 1 g/kg body weight of honey daily in separate doses for the 4-week period. The control group ingested the same dose of honey-flavored corn syrup as a placebo.
According to the AR symptoms scored at the start, week 4, and week 8 of the study, at week 4, both groups showed progressive improvement in the symptoms, however, at week 8, only the case group showed continuous improvement in the symptom score.
The ingested honey group showed a significant improvement in individual AR symptoms after week 8 and the efficacy in reducing the symptoms persisted for a month after the cessation of the honey treatment.
The results suggested that honey processed certain chemical compounds that were not found in the corn syrup for the treatment of AR.
Some researchers suggested that long-term intake of raw honey can help to ameliorate allergy symptoms by regularly exposing to pollen, similarly to the allergy injection in desensitizing pollen-program.
If this result is true then only local honey can process the anti-AR symptoms compared to honey unlocalized pollen.
Taken altogether, honey may be considered a functional remedy for the prevention and treatment of AR symptoms, regardless of the types of honey, pending the confirmation of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Ingestion of honey improves the symptoms of allergic rhinitis: evidence from a randomized placebo-controlled trial in the East coast of Peninsular Malaysia by Asha'ari ZA1, Ahmad MZ, Jihan WS, Che CM, Leman I. (PubMed)
(2) Will honey relieve my seasonal allergies? by Allergists
(3) The Public Health Impact of Parent-Reported Childhood Food Allergies in the United States by Ruchi S. Gupta, Christopher M. Warren, Bridget M. Smith, Jesse A. Blumenstock, Jialing Jiang, Matthew M. Davis, Kari C. Nadeau. (APP News and Journals)
Allergies are a faulty reaction of the immune system responses against harmful substances that enter the body.
Symptoms and diseases associated with allergy include sinus swelling, seasonal and returning allergies, hay fever, and nasal allergies.
Believe it or not, Penicillin, antibiotic medicine is the most common allergy trigger in drug allergies. 10 percent of people are allergic after using the medicine.
According to the statistics, in the US, approximately, more than 50 million Americans have experienced various types of allergies each year and 15 million Americans have food allergies, including 5.9 million children under age 18.
In other words, 1 in 13 children suffers from a food allergy. About 30 percent of children with food allergies are allergic to more than one food.
The findings strongly suggested that foods are the most common and major cause of allergic onset.
Dr. Ruchi S. Gupta and colleagues in the allergic team in examining the food allergies in children wrote, "Overall, estimated current FA prevalence was 7.6%,.The most prevalent allergens were peanut (2.2%), milk (1.9%), shellfish (1.3%), and tree nut (1.2%)".
And, "Among food-allergic children, 42.3% reported ≥1 severe FA and 39.9% reported multiple FA. Furthermore, 19.0% reported ≥1 FA-related emergency department visit in the previous year and 42.0% reported ≥1-lifetime FA-related emergency department visit, whereas 40.7% had a current epinephrine autoinjector prescription.
Honey is a miraculous product made by bees using nectar from flowers.
The rich golden liquid is considered one of the healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.
Researchers on finding a natural compound for the treatment of allergies examined the honey effects in the treatment of allergic rhinitis (AR).
The prospective randomized placebo-controlled study included 40 AR patients divided equally into a case group and a control group. All the subjects received a daily dose of 10 mg of loratadine for 4 weeks.
The case group then ingested 1 g/kg body weight of honey daily in separate doses for the 4-week period. The control group ingested the same dose of honey-flavored corn syrup as a placebo.
According to the AR symptoms scored at the start, week 4, and week 8 of the study, at week 4, both groups showed progressive improvement in the symptoms, however, at week 8, only the case group showed continuous improvement in the symptom score.
The ingested honey group showed a significant improvement in individual AR symptoms after week 8 and the efficacy in reducing the symptoms persisted for a month after the cessation of the honey treatment.
The results suggested that honey processed certain chemical compounds that were not found in the corn syrup for the treatment of AR.
Some researchers suggested that long-term intake of raw honey can help to ameliorate allergy symptoms by regularly exposing to pollen, similarly to the allergy injection in desensitizing pollen-program.
If this result is true then only local honey can process the anti-AR symptoms compared to honey unlocalized pollen.
Taken altogether, honey may be considered a functional remedy for the prevention and treatment of AR symptoms, regardless of the types of honey, pending the confirmation of a large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Ingestion of honey improves the symptoms of allergic rhinitis: evidence from a randomized placebo-controlled trial in the East coast of Peninsular Malaysia by Asha'ari ZA1, Ahmad MZ, Jihan WS, Che CM, Leman I. (PubMed)
(2) Will honey relieve my seasonal allergies? by Allergists
(3) The Public Health Impact of Parent-Reported Childhood Food Allergies in the United States by Ruchi S. Gupta, Christopher M. Warren, Bridget M. Smith, Jesse A. Blumenstock, Jialing Jiang, Matthew M. Davis, Kari C. Nadeau. (APP News and Journals)
Friday, March 5, 2021
Cruciferous Vegetables Inhibit Menopausal Symptoms of Breast Cancer Survivors
Cancer is the class of diseases associated with the growth of the cells disorderly and uncontrollably due to the alternation of DNA.
Most cases of cancer begin in the cells on the surface of the inner lining tissues of the organ or gland. At the early stage, most cancers are asymptomatic.
The development of cancer can be divided into three different stages
* Initiation
Initiation is characteristic by irreversible mutation of DNA of a particular cell which does not undergo DNA repair (by enzymes) or undergoes faulty DNA repair, including gene deletion or insertion, gene slices, etc.
* Promotion
In the promotion stage, the mutation cells involve in uncontrolled growth and proliferation of mutated cells as it promotes the expression of its mutation gene and in its replication. In time these cells lose their normal abilities and just reproduce.
* Progression
In the progression stage, the cancerous cells invade nearby tissues and migrate to other tissues via lymph or blood
Breast cancer is a medical condition characterized by irregular cell growth in the breast tissues. At the late stage, the cancerous cells may travel a distance away to infect other organs and tissues from the original site.
The study of bioactive green tea polyphenol epigallocatechin-3-gallate (EGCG) was found to decrease the progression of breast cancer cells with Her-2/neu overexpression, through many mechanisms.
Unlike general breast cancer which processes either receptors for estrogen or progesterone and/or receptors with a protein called HER2, triple-negative breast cancer is a form of breast cancer that does not share the aforementioned characteristics.
In other words, triple-negative breast cancer does not have receptors of estrogen or progesterone, or genetic preposition.
Compared to the malignant nature, triple-negative and basal-like breast cancers are highly invasive which can grow and spread quickly to other tissues and organs through lymph and blood.
Also compared to other breast cancer, with decreased risk after 5 years, triple-negative breast cancers have a substantially higher recurrent rate within 5 years after treatment.
Triple-negative breast cancer shares symptoms similar to those of breast cancer and risk factor except in the form of the genetic preposition.
Cruciferous vegetables are a group of vegetables, belongings to the family Brassicaceae (also called Cruciferae) with many genera, species, and cultivated all over the world in suitable climate for commercial profits, including cauliflower, cabbage, kale, garden cress, bok choy, broccoli, Brussels sprouts, and green leafy vegetables.
On finding a potential compound for the treatment of cancer, researchers examined the association between dietary intake of soy or cruciferous vegetables and breast cancer treatment-related symptoms among Chinese-American (CA) and Non-Hispanic White (NHW) breast cancer survivors.
The joint cross-sectional study led by the Georgetown University included 192 CA and 173 NHW female breast cancer survivors (stages 0-III, diagnosed between 2006 and 2012) recruited from two California cancer registries, who had completed primary treatment.
Based on the Patient-reported data on treatment-related symptoms and potential covariates collected via telephone interviews, * Soy foods and cruciferous vegetable intake ranged from no intake to 431 and 865 g/day, respectively, and was higher in CA survivors.
* Higher soy food intake was associated with lower odds of menopausal symptoms (≥ 24.0 vs. 0 g/day, OR 0.51, 95% CI 0.25, 1.03), and fatigue (≥ 24.0 vs. 0 g/day, OR 0.43, 95% CI 0.22, 0.84), particularly in NHW survivors only.
* Compared with low intake, higher cruciferous vegetable intake was associated with lower odds of experiencing menopausal symptoms (≥ 70.8 vs. < 33.0 g/day, OR 0.50, 95% CI 0.25, 0.97) in the overall population.
Taken altogether, cruciferous vegetables may be considered functional foods for the treatment of breast cancer survivors' menopausal symptoms and fatigue, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Dietary intake of soy and cruciferous vegetables and treatment-related symptoms in Chinese-American and non-Hispanic White breast cancer survivors by Nomura SJO1, Hwang YT2, Gomez SL3, Fung TT4,5, Yeh SL6, Dash C1, Allen L3, Philips S7, Hilakivi-Clarke L1, Zheng YL1, Wang JH. (PubMed)
Most cases of cancer begin in the cells on the surface of the inner lining tissues of the organ or gland. At the early stage, most cancers are asymptomatic.
The development of cancer can be divided into three different stages
* Initiation
Initiation is characteristic by irreversible mutation of DNA of a particular cell which does not undergo DNA repair (by enzymes) or undergoes faulty DNA repair, including gene deletion or insertion, gene slices, etc.
* Promotion
In the promotion stage, the mutation cells involve in uncontrolled growth and proliferation of mutated cells as it promotes the expression of its mutation gene and in its replication. In time these cells lose their normal abilities and just reproduce.
* Progression
In the progression stage, the cancerous cells invade nearby tissues and migrate to other tissues via lymph or blood
Breast cancer is a medical condition characterized by irregular cell growth in the breast tissues. At the late stage, the cancerous cells may travel a distance away to infect other organs and tissues from the original site.
The study of bioactive green tea polyphenol epigallocatechin-3-gallate (EGCG) was found to decrease the progression of breast cancer cells with Her-2/neu overexpression, through many mechanisms.
Unlike general breast cancer which processes either receptors for estrogen or progesterone and/or receptors with a protein called HER2, triple-negative breast cancer is a form of breast cancer that does not share the aforementioned characteristics.
In other words, triple-negative breast cancer does not have receptors of estrogen or progesterone, or genetic preposition.
Compared to the malignant nature, triple-negative and basal-like breast cancers are highly invasive which can grow and spread quickly to other tissues and organs through lymph and blood.
Also compared to other breast cancer, with decreased risk after 5 years, triple-negative breast cancers have a substantially higher recurrent rate within 5 years after treatment.
Triple-negative breast cancer shares symptoms similar to those of breast cancer and risk factor except in the form of the genetic preposition.
Cruciferous vegetables are a group of vegetables, belongings to the family Brassicaceae (also called Cruciferae) with many genera, species, and cultivated all over the world in suitable climate for commercial profits, including cauliflower, cabbage, kale, garden cress, bok choy, broccoli, Brussels sprouts, and green leafy vegetables.
On finding a potential compound for the treatment of cancer, researchers examined the association between dietary intake of soy or cruciferous vegetables and breast cancer treatment-related symptoms among Chinese-American (CA) and Non-Hispanic White (NHW) breast cancer survivors.
The joint cross-sectional study led by the Georgetown University included 192 CA and 173 NHW female breast cancer survivors (stages 0-III, diagnosed between 2006 and 2012) recruited from two California cancer registries, who had completed primary treatment.
Based on the Patient-reported data on treatment-related symptoms and potential covariates collected via telephone interviews, * Soy foods and cruciferous vegetable intake ranged from no intake to 431 and 865 g/day, respectively, and was higher in CA survivors.
* Higher soy food intake was associated with lower odds of menopausal symptoms (≥ 24.0 vs. 0 g/day, OR 0.51, 95% CI 0.25, 1.03), and fatigue (≥ 24.0 vs. 0 g/day, OR 0.43, 95% CI 0.22, 0.84), particularly in NHW survivors only.
* Compared with low intake, higher cruciferous vegetable intake was associated with lower odds of experiencing menopausal symptoms (≥ 70.8 vs. < 33.0 g/day, OR 0.50, 95% CI 0.25, 0.97) in the overall population.
Taken altogether, cruciferous vegetables may be considered functional foods for the treatment of breast cancer survivors' menopausal symptoms and fatigue, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Dietary intake of soy and cruciferous vegetables and treatment-related symptoms in Chinese-American and non-Hispanic White breast cancer survivors by Nomura SJO1, Hwang YT2, Gomez SL3, Fung TT4,5, Yeh SL6, Dash C1, Allen L3, Philips S7, Hilakivi-Clarke L1, Zheng YL1, Wang JH. (PubMed)
Thursday, March 4, 2021
Coffee and Coffee Caffeine in Reducing the Risk of Breast Cancer Selectively
Recent studies suggested that coffee and coffee caffeine may have a potential effect in reduced risk and treatment of breast cancer, selectively.
Coffee, becoming a popular and social beverage all over the world, particular in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.
In the review of literature from database of PubMed with selection of 37 published articles, involving 59,018 breast cancer cases and 966,263 participants, suggested that
1. There is no significant association between coffee and coffee caffeine intake and breast cancer risk
2. Post menopause women drinking coffee daily and regularly have a reduced risk of breast cancer developing.
3. Women who are BRCA1 mutation carriers showed a positive risk of breast cancer from coffee intake
The study also indicated that for additional cup of coffee consumed risk of breast cancer decreased by 2% and 1% for every 200mg/day increment in caffeine intake.
Contrastively, in a case-control analysis on 1,690 women with a BRCA1 or BRCA2 mutation from 40 centers in 4 countries.to determine coffee and coffee caffeine intake against the risk of breast cancer, returned self-administered questionnaire. showed a significant correlation of coffee intake in the elevated breast caner risk.
Women with breast cancer in BRCA carriers who habitually drank 0, 1-3, 4-5 and 6 or more cups of coffee showed a relative risk odds ratio of 1.00, 0.90, 0.75 and 0.31, respectively.
The finding evidence of relative odd ratio suggested that risk of breast cancer was reduced in this group of women linearly to numbers of coffee and coffee caffeine consumed daily.
Dr, Jiang W, lead author said, " (According to the findings) women with BRCA gene mutation, coffee consumption is unlikely to be harmful and that high levels of consumption may in fact be related to reduced breast cancer risk"
Interesting, in the investigated the common A to C polymorphism in the CYP1A2 gene associated with decreased enzyme inducibility and impaired caffeine metabolism of caffeine to examine the risk of breast cancer in BRCA1 mutation carriers of 411 BRCA1 mutation carriers (170 cases and 241 controls) researchers at the University of Toronto found that risk of breast cancer decrease significantly by 64% in BRCA1 mutation carriers with at least one C polymorphism in the CYP1A2 gene but not in CYP1A2 AA group in compared to women who never consumed coffee.
Collectively, coffee and coffee caffeine may only benefit to certain ages and genes expression but harmful to the others. Further cohort studies are necessary to clarify these controversies..
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Coffee and caffeine intake and breast cancer risk: an updated dose-response meta-analysis of 37 published studies by Jiang W1, Wu Y, Jiang X.(PubMed)
(2) Coffee consumption and breast cancer risk among BRCA1 and BRCA2 mutation carriers by Nkondjock A1, Ghadirian P, Kotsopoulos J, Lubinski J, Lynch H, Kim-Sing C, Horsman D, Rosen B, Isaacs C, Weber B, Foulkes W, Ainsworth P, Tung N, Eisen A, Friedman E, Eng C, Sun P, Narod SA.(PubMed)
(3) The CYP1A2 genotype modifies the association between coffee consumption and breast cancer risk among BRCA1 mutation carriers by Kotsopoulos J1, Ghadirian P, El-Sohemy A, Lynch HT, Snyder C, Daly M, Domchek S, Randall S, Karlan B, Zhang P, Zhang S, Sun P, Narod SA.(PubMed)
Coffee, becoming a popular and social beverage all over the world, particular in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.
In the review of literature from database of PubMed with selection of 37 published articles, involving 59,018 breast cancer cases and 966,263 participants, suggested that
1. There is no significant association between coffee and coffee caffeine intake and breast cancer risk
2. Post menopause women drinking coffee daily and regularly have a reduced risk of breast cancer developing.
3. Women who are BRCA1 mutation carriers showed a positive risk of breast cancer from coffee intake
The study also indicated that for additional cup of coffee consumed risk of breast cancer decreased by 2% and 1% for every 200mg/day increment in caffeine intake.
Contrastively, in a case-control analysis on 1,690 women with a BRCA1 or BRCA2 mutation from 40 centers in 4 countries.to determine coffee and coffee caffeine intake against the risk of breast cancer, returned self-administered questionnaire. showed a significant correlation of coffee intake in the elevated breast caner risk.
Women with breast cancer in BRCA carriers who habitually drank 0, 1-3, 4-5 and 6 or more cups of coffee showed a relative risk odds ratio of 1.00, 0.90, 0.75 and 0.31, respectively.
The finding evidence of relative odd ratio suggested that risk of breast cancer was reduced in this group of women linearly to numbers of coffee and coffee caffeine consumed daily.
Dr, Jiang W, lead author said, " (According to the findings) women with BRCA gene mutation, coffee consumption is unlikely to be harmful and that high levels of consumption may in fact be related to reduced breast cancer risk"
Interesting, in the investigated the common A to C polymorphism in the CYP1A2 gene associated with decreased enzyme inducibility and impaired caffeine metabolism of caffeine to examine the risk of breast cancer in BRCA1 mutation carriers of 411 BRCA1 mutation carriers (170 cases and 241 controls) researchers at the University of Toronto found that risk of breast cancer decrease significantly by 64% in BRCA1 mutation carriers with at least one C polymorphism in the CYP1A2 gene but not in CYP1A2 AA group in compared to women who never consumed coffee.
Collectively, coffee and coffee caffeine may only benefit to certain ages and genes expression but harmful to the others. Further cohort studies are necessary to clarify these controversies..
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Coffee and caffeine intake and breast cancer risk: an updated dose-response meta-analysis of 37 published studies by Jiang W1, Wu Y, Jiang X.(PubMed)
(2) Coffee consumption and breast cancer risk among BRCA1 and BRCA2 mutation carriers by Nkondjock A1, Ghadirian P, Kotsopoulos J, Lubinski J, Lynch H, Kim-Sing C, Horsman D, Rosen B, Isaacs C, Weber B, Foulkes W, Ainsworth P, Tung N, Eisen A, Friedman E, Eng C, Sun P, Narod SA.(PubMed)
(3) The CYP1A2 genotype modifies the association between coffee consumption and breast cancer risk among BRCA1 mutation carriers by Kotsopoulos J1, Ghadirian P, El-Sohemy A, Lynch HT, Snyder C, Daly M, Domchek S, Randall S, Karlan B, Zhang P, Zhang S, Sun P, Narod SA.(PubMed)
Wednesday, March 3, 2021
Green Tea, the Best in Prevention and Treatment of Prostate Cancer in Clinical Diagnosis
Prostate cancer is a condition in which the cells of the prostate have become cancerous, causing abnormal cell growth with the possibility of spreading to the distant parts of the body.
Most prostate cancers are slow-growing and prostate cancer may be detected during physical (rectum) exams.
Green tea may be used as a functional food in the prevention and treatment of prostate cancer, a renowned institute study suggested
Green tea, a precious drink processes numbers of health benefits known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine,or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. Adding a slice of ginger will do the trick.
According to the Fu Jen Catholic University, New Taipei City, catechin nanoemulsion preparation showed the highest inhibition of growth of PC-3 tumor cells, with concentration being 15.4 μg/mL and 8.5 μg/mL
The inhibition of prostate cancer cell line is observed in cell cycle arrest by regulated proteins involved in cell cycle division, namely cyclin A, cyclin B, cyclin-dependent kinase 2, and cyclin-dependent kinase 1 expression and activated cell apoptosis and survival.
Dr. Tsai YJ, the lead author said, " catechin extract and nanoemulsion could induce apoptosis of PC-3 cells through decrease in B-cell lymphoma 2 (BCL-2) expression and increase in cytochrome c expression( in the induction of apoptosis) for activation of caspase-3, caspase-8, and caspase-9 (involved cell death)".
Furthermore, in the recruited 404 PCA cases and 395 controls from the same hospital who completed data on habitual tea consumption, including green, oolong, black, and pu'er tea regular green drinkers have a significantly reduced risk in prostate cancer development.
The review of the inverse relation of tea drinkers and risk of prostate cancer has shown explicitly:
1. total of 32 cases and 50 controls reported habitual green tea drinking, showing an adjusted OR of 0.60 (95% confidence interval (CI): 0.37, 0.98).
2. A moderate excess risk was observed among the habitual pu'er tea drinkers (OR=1.44, 95% CI: 1.02, 1.91).
3. A significantly lower intake of EGCG was observed among cases (54.4 mg) than the controls (72.5 mg).
Additionally, the differentiation of 7 observational studies and 3 randomized controlled trials retrieved from Cochrane Library, PubMed, ScienceDirect Online, and hand searching. the database, also reveals an interest correlated incidence of PCa decrease with each 1 cup/day increase of green tea.
According to the study, "higher green tea consumption was linearly reduced PCa risk with more than 7 cups/day and green tea catechins were effective for preventing PCa".
Collectively, green tea consumption is associated inversely with the risk of PCA but the injection of a large amount of green tea supplement should be taken with care in prevented toxicity.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Sources
(1) Preparation of catechin extracts and nanoemulsions from green tea leaf waste and their inhibition effect on prostate cancer cell PC-3 by Tsai YJ1, Chen BH1.(PubMed)
(2)Reduced prostate cancer risk with green tea and epigallocatechin 3-gallate intake among Hong Kong Chinese men by Lee PMY1, Ng CF2, Liu ZM3, Ho WM4, Lee MK5, Wang F1, Kan HD6, He YH7, Ng SSM2, Wong SYS1, Tse LA1.(PubMed)
(3) Green tea and the risk of prostate cancer: A systematic review and meta-analysis by Guo Y1, Zhi F, Chen P, Zhao K, Xiang H, Mao Q, Wang X, Zhang X.(PubMed)
Most prostate cancers are slow-growing and prostate cancer may be detected during physical (rectum) exams.
Green tea may be used as a functional food in the prevention and treatment of prostate cancer, a renowned institute study suggested
Green tea, a precious drink processes numbers of health benefits known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine,or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. Adding a slice of ginger will do the trick.
According to the Fu Jen Catholic University, New Taipei City, catechin nanoemulsion preparation showed the highest inhibition of growth of PC-3 tumor cells, with concentration being 15.4 μg/mL and 8.5 μg/mL
The inhibition of prostate cancer cell line is observed in cell cycle arrest by regulated proteins involved in cell cycle division, namely cyclin A, cyclin B, cyclin-dependent kinase 2, and cyclin-dependent kinase 1 expression and activated cell apoptosis and survival.
Dr. Tsai YJ, the lead author said, " catechin extract and nanoemulsion could induce apoptosis of PC-3 cells through decrease in B-cell lymphoma 2 (BCL-2) expression and increase in cytochrome c expression( in the induction of apoptosis) for activation of caspase-3, caspase-8, and caspase-9 (involved cell death)".
Furthermore, in the recruited 404 PCA cases and 395 controls from the same hospital who completed data on habitual tea consumption, including green, oolong, black, and pu'er tea regular green drinkers have a significantly reduced risk in prostate cancer development.
The review of the inverse relation of tea drinkers and risk of prostate cancer has shown explicitly:
1. total of 32 cases and 50 controls reported habitual green tea drinking, showing an adjusted OR of 0.60 (95% confidence interval (CI): 0.37, 0.98).
2. A moderate excess risk was observed among the habitual pu'er tea drinkers (OR=1.44, 95% CI: 1.02, 1.91).
3. A significantly lower intake of EGCG was observed among cases (54.4 mg) than the controls (72.5 mg).
Additionally, the differentiation of 7 observational studies and 3 randomized controlled trials retrieved from Cochrane Library, PubMed, ScienceDirect Online, and hand searching. the database, also reveals an interest correlated incidence of PCa decrease with each 1 cup/day increase of green tea.
According to the study, "higher green tea consumption was linearly reduced PCa risk with more than 7 cups/day and green tea catechins were effective for preventing PCa".
Collectively, green tea consumption is associated inversely with the risk of PCA but the injection of a large amount of green tea supplement should be taken with care in prevented toxicity.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Sources
(1) Preparation of catechin extracts and nanoemulsions from green tea leaf waste and their inhibition effect on prostate cancer cell PC-3 by Tsai YJ1, Chen BH1.(PubMed)
(2)Reduced prostate cancer risk with green tea and epigallocatechin 3-gallate intake among Hong Kong Chinese men by Lee PMY1, Ng CF2, Liu ZM3, Ho WM4, Lee MK5, Wang F1, Kan HD6, He YH7, Ng SSM2, Wong SYS1, Tse LA1.(PubMed)
(3) Green tea and the risk of prostate cancer: A systematic review and meta-analysis by Guo Y1, Zhi F, Chen P, Zhao K, Xiang H, Mao Q, Wang X, Zhang X.(PubMed)
Tuesday, March 2, 2021
Healthy Food Tomato Inhibits Hepatic Steatosis in Vivo
Hepatic steatosis is a medical condition caused by the accumulation of fat in the liver.
In other words, if the intrahepatic fat of your liver is more than 5% of liver weight, you are considered to have hepatic steatosis. Over time, untreated hepatic steatosis can lead to liver metabolic dysfunction, inflammation, and advanced forms of nonalcoholic fatty liver disease.
Epidemiologically, hepatic steatosis has been found to induce complications in patients with obesity, alcohol intoxication, and/or hepatic disorders.
There are several mechanisms involved in the accumulation of intrahepatic fat, including increased flux of fatty acids to the liver, increased de novo lipogenesis, and/or reduced clearance through β-oxidation or very-low-density lipoprotein secretion.
People who are obese, having the condition of insulin resistance or diabetes, dyslipidemia, hypertension, metabolic syndrome, rapid weight loss, using hepatotoxic medications total parenteral nutrition (TPN) are at the increased risk of hepatic steatosis.
Out of many prevalent factors involved in the onset of hepatic steatosis, some researchers suggested that the promotion of the Western diet over the past few decades in the Western world may have a strong and negative impact that accelerates the incidence onset.
Dr. Michael D. Roberts, the lead scientist wrote, "Six weeks of WD feeding caused hepatic steatosis development as evidenced by the 2.25-fold increase in liver triacylglycerol content, but did not induce advanced liver disease (i.e., no overt inflammation or fibrosis)".
And, "sub-chronic WD feeding appears to increase hepatic steatosis development over a 6-week period but only induces select inflammation-related liver transcripts, mostly acute phase response genes. These findings continue to outline the early stages of NAFLD development prior to overt liver inflammation and advanced liver disease".
The results strongly suggested the risk of the Western diet on hepatic steatosis developing.
Tomato is red, edible fruit, genus Solanum, belonging to family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
In the urgency to discover healthy foods for the treatment of hepatic steatosis, researchers examined the effect of tomato consumption on biomarkers and gene expression related to lipid metabolism in rats with induced steatosis.
The study included 24 adult male Sprague-Dawley rats (8 weeks old) randomly assigned to (n = 6 rats/group) four experimental groups, including NA (normal diet and water), NL (normal diet and tomato juice), HA (high-fat diet and water) and HL (high-fat diet and tomato juice).
According to the tested assays, before treatment of tomato, HA group fed high-fat diet-induced hepatic steatosis confirmed by the levels of alanine aminotransferase and aspartate aminotransferase, an indication of liver stress and injury.
Tomato treated group showed a significant increase of levels of lycopene and its secondary metabolites in the livers of these animals, particularly in HL than in NL group, apparently due to higher absorption (63.07 vs. 44.45%).
Furthermore, tomato treated group protected the liver by alleviating oxidative stress through the reduction of isoprostanes in the urine observed by increased levels of antioxidant enzymes.
Moreover, levels of high-density lipoprotein were also increased in the HL group compared to the HA group.
Interestingly, overexpression of several genes related to lipid metabolism was also found in the HL group compared to nontreatment groups.
In other words, tomato inhibited the onset and progression of hepatic steatosis in high-fat diet mice by inhibiting liver oxidative stress and enhancing lipid metabolism.
Dr. Martín-Pozuelo G, the lead scientist wrote, "The consumption of tomato juice and tomato products reduced hallmarks of steatosis, plasmatic triglycerides, and very-low-density lipoproteins, and increased lipid metabolism by inducing an overexpression of genes involved in more efficient fatty acid oxidation".
Taken altogether, tomato may be considered a dietary supplement for the prevention and treatment of hepatic steatosis, pending to large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The effect of tomato juice supplementation on biomarkers and gene expression related to lipid metabolism in rats with induced hepatic steatosis by Martín-Pozuelo G1, Navarro-González I, González-Barrio R, Santaella M, García-Alonso J, Hidalgo N, Gómez-Gallego C, Ros G, Periago MJ. (PubMed)
(2) Lipid biomarkers and metabolic effects of lycopene from tomato juice on liver of rats with induced hepatic steatosis by Bernal C1, Martín-Pozuelo G, Lozano AB, Sevilla A, García-Alonso J, Canovas M, Periago MJ. (PubMed)
(3) Western diet-induced hepatic steatosis and alterations in the liver transcriptome in adult Brown-Norway rats by Michael D. Roberts, C. Brooks Mobley, Ryan G. Toedebush, Alexander J. Heese, Conan Zhu,Anna E. Krieger, Clayton L. Cruthirds, Christopher M. Lockwood, John C. Hofheins,Charles E. Wiedmeyer, Heather J. Leidy, Frank W. Booth, and R. Scott Rector. (PMC)
In other words, if the intrahepatic fat of your liver is more than 5% of liver weight, you are considered to have hepatic steatosis. Over time, untreated hepatic steatosis can lead to liver metabolic dysfunction, inflammation, and advanced forms of nonalcoholic fatty liver disease.
Epidemiologically, hepatic steatosis has been found to induce complications in patients with obesity, alcohol intoxication, and/or hepatic disorders.
There are several mechanisms involved in the accumulation of intrahepatic fat, including increased flux of fatty acids to the liver, increased de novo lipogenesis, and/or reduced clearance through β-oxidation or very-low-density lipoprotein secretion.
People who are obese, having the condition of insulin resistance or diabetes, dyslipidemia, hypertension, metabolic syndrome, rapid weight loss, using hepatotoxic medications total parenteral nutrition (TPN) are at the increased risk of hepatic steatosis.
Out of many prevalent factors involved in the onset of hepatic steatosis, some researchers suggested that the promotion of the Western diet over the past few decades in the Western world may have a strong and negative impact that accelerates the incidence onset.
Dr. Michael D. Roberts, the lead scientist wrote, "Six weeks of WD feeding caused hepatic steatosis development as evidenced by the 2.25-fold increase in liver triacylglycerol content, but did not induce advanced liver disease (i.e., no overt inflammation or fibrosis)".
And, "sub-chronic WD feeding appears to increase hepatic steatosis development over a 6-week period but only induces select inflammation-related liver transcripts, mostly acute phase response genes. These findings continue to outline the early stages of NAFLD development prior to overt liver inflammation and advanced liver disease".
The results strongly suggested the risk of the Western diet on hepatic steatosis developing.
Tomato is red, edible fruit, genus Solanum, belonging to family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.
In the urgency to discover healthy foods for the treatment of hepatic steatosis, researchers examined the effect of tomato consumption on biomarkers and gene expression related to lipid metabolism in rats with induced steatosis.
The study included 24 adult male Sprague-Dawley rats (8 weeks old) randomly assigned to (n = 6 rats/group) four experimental groups, including NA (normal diet and water), NL (normal diet and tomato juice), HA (high-fat diet and water) and HL (high-fat diet and tomato juice).
According to the tested assays, before treatment of tomato, HA group fed high-fat diet-induced hepatic steatosis confirmed by the levels of alanine aminotransferase and aspartate aminotransferase, an indication of liver stress and injury.
Tomato treated group showed a significant increase of levels of lycopene and its secondary metabolites in the livers of these animals, particularly in HL than in NL group, apparently due to higher absorption (63.07 vs. 44.45%).
Furthermore, tomato treated group protected the liver by alleviating oxidative stress through the reduction of isoprostanes in the urine observed by increased levels of antioxidant enzymes.
Moreover, levels of high-density lipoprotein were also increased in the HL group compared to the HA group.
Interestingly, overexpression of several genes related to lipid metabolism was also found in the HL group compared to nontreatment groups.
In other words, tomato inhibited the onset and progression of hepatic steatosis in high-fat diet mice by inhibiting liver oxidative stress and enhancing lipid metabolism.
Dr. Martín-Pozuelo G, the lead scientist wrote, "The consumption of tomato juice and tomato products reduced hallmarks of steatosis, plasmatic triglycerides, and very-low-density lipoproteins, and increased lipid metabolism by inducing an overexpression of genes involved in more efficient fatty acid oxidation".
Taken altogether, tomato may be considered a dietary supplement for the prevention and treatment of hepatic steatosis, pending to large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The effect of tomato juice supplementation on biomarkers and gene expression related to lipid metabolism in rats with induced hepatic steatosis by Martín-Pozuelo G1, Navarro-González I, González-Barrio R, Santaella M, García-Alonso J, Hidalgo N, Gómez-Gallego C, Ros G, Periago MJ. (PubMed)
(2) Lipid biomarkers and metabolic effects of lycopene from tomato juice on liver of rats with induced hepatic steatosis by Bernal C1, Martín-Pozuelo G, Lozano AB, Sevilla A, García-Alonso J, Canovas M, Periago MJ. (PubMed)
(3) Western diet-induced hepatic steatosis and alterations in the liver transcriptome in adult Brown-Norway rats by Michael D. Roberts, C. Brooks Mobley, Ryan G. Toedebush, Alexander J. Heese, Conan Zhu,Anna E. Krieger, Clayton L. Cruthirds, Christopher M. Lockwood, John C. Hofheins,Charles E. Wiedmeyer, Heather J. Leidy, Frank W. Booth, and R. Scott Rector. (PMC)
Monday, March 1, 2021
Green Tea Shows a Strong Anti Obesity Activity in Vivo
Green tea is found to consist of an anti-obesity function, a recent study by a popular institute suggested.
Green tea, considered as a functional food, linking numbers of health benefits has been reported by several renowned research and studies. However, as yin in nature herbal medicine or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. But adding a slice of ginger will do the trick.
Obesity is a medical condition of excess body fat accumulated over time. A person is considered obese if excess body weight relative to the height is over 30 in BMI index.
According to the University of the Punjab, Epigallocatechin gallate, a polyphenol found in tea plants exhibited anti obesity effect through modulation of thePPAR[gamma] pathway in metabolism involved fat cells/adipose tissues.
In an animal study, the chemical constituent stopped the adipogenic cell differentiation through different proteins and transcription factors in the expression of adipocyte formation which is considered as fat cell development in contribution to obesity.
Dr. Javaid MS, the lead author in the study said, "Docking analysis of PPAR gamma and epigallocatechin gallate demonstrated that epigallocatechin gallate binds with PPAR gamma at its active site and blocks its activity".
Also, in animal induced by high fat diet, green tea Epigallocatechin 3-gallate (EGCG),exerted anti obesity effects through reduced plasma glucose and alleviate complications of diabetes by attenuating advanced glycation end products (AGEs) formation involved proteins or lipids expression.
Dietary EGCG tested in C57BL/6 mice induced by high-fat diet with or without ECGC for 17 weeks and compared to a control group placed on low-fat diet for the same period, also showed a significanty reduced weight gain, plasma glucose, insulin level, liver and kidney weight, which can be seen in obesity in compared control mice.
Importantly, green tea Epigallocatechin 3-gallate (EGCG fed mice novally decreased the levels of AGEs(advanced glycation end product) in both plasma and liver while inhibiting the receptor for AGE (RAGE) expression of activating Nrf2, antioxidant response and enhanced anti oxidative stress ratio of GSH/GSSG.
Other searchers opinionated the effect of green tea in reduced fat/adipose tissues accumulation in obese subject is a result of the pro-oxidant action of EGCG, in de activated cellular production of reactive oxygen species, through indication of adenosine monophosphate-activated protein kinase in suppressed gene and protein expression of enzymes and transcription factors involved in adipogenesis and lipogenesis(fat and adiposed metabolism).
Taking together, green tea with all the phytochemicals may be used as anti obesity functional food to help control hyperglycemia, reduce weight, and alleviate diabetes complications.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Sources
(1) Epigallocatechin Gallate as an anti-obesity therapeutic compound: an in silico approach for structure-based drug designing by Javaid MS1, Latief N1, Ijaz B1, Ashfaq UA2(PubMed).
(2) Green tea epigallocatechin 3-gallate alleviates hyperglycemia and reduces advanced glycation end products via nrf2 pathway in mice with high fat diet-induced obesity by Sampath C1, Rashid MR1, Sang S2, Ahmedna M3(PubMed)
(3) Beneficial Effects of Tea and the Green Tea Catechin Epigallocatechin-3-gallate on Obesity by Suzuki T1, Pervin M2, Goto S3, Isemura M4, Nakamura Y5.(PubMed)
Green tea, considered as a functional food, linking numbers of health benefits has been reported by several renowned research and studies. However, as yin in nature herbal medicine or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. But adding a slice of ginger will do the trick.
Obesity is a medical condition of excess body fat accumulated over time. A person is considered obese if excess body weight relative to the height is over 30 in BMI index.
According to the University of the Punjab, Epigallocatechin gallate, a polyphenol found in tea plants exhibited anti obesity effect through modulation of thePPAR[gamma] pathway in metabolism involved fat cells/adipose tissues.
In an animal study, the chemical constituent stopped the adipogenic cell differentiation through different proteins and transcription factors in the expression of adipocyte formation which is considered as fat cell development in contribution to obesity.
Dr. Javaid MS, the lead author in the study said, "Docking analysis of PPAR gamma and epigallocatechin gallate demonstrated that epigallocatechin gallate binds with PPAR gamma at its active site and blocks its activity".
Also, in animal induced by high fat diet, green tea Epigallocatechin 3-gallate (EGCG),exerted anti obesity effects through reduced plasma glucose and alleviate complications of diabetes by attenuating advanced glycation end products (AGEs) formation involved proteins or lipids expression.
Dietary EGCG tested in C57BL/6 mice induced by high-fat diet with or without ECGC for 17 weeks and compared to a control group placed on low-fat diet for the same period, also showed a significanty reduced weight gain, plasma glucose, insulin level, liver and kidney weight, which can be seen in obesity in compared control mice.
Importantly, green tea Epigallocatechin 3-gallate (EGCG fed mice novally decreased the levels of AGEs(advanced glycation end product) in both plasma and liver while inhibiting the receptor for AGE (RAGE) expression of activating Nrf2, antioxidant response and enhanced anti oxidative stress ratio of GSH/GSSG.
Other searchers opinionated the effect of green tea in reduced fat/adipose tissues accumulation in obese subject is a result of the pro-oxidant action of EGCG, in de activated cellular production of reactive oxygen species, through indication of adenosine monophosphate-activated protein kinase in suppressed gene and protein expression of enzymes and transcription factors involved in adipogenesis and lipogenesis(fat and adiposed metabolism).
Taking together, green tea with all the phytochemicals may be used as anti obesity functional food to help control hyperglycemia, reduce weight, and alleviate diabetes complications.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Sources
(1) Epigallocatechin Gallate as an anti-obesity therapeutic compound: an in silico approach for structure-based drug designing by Javaid MS1, Latief N1, Ijaz B1, Ashfaq UA2(PubMed).
(2) Green tea epigallocatechin 3-gallate alleviates hyperglycemia and reduces advanced glycation end products via nrf2 pathway in mice with high fat diet-induced obesity by Sampath C1, Rashid MR1, Sang S2, Ahmedna M3(PubMed)
(3) Beneficial Effects of Tea and the Green Tea Catechin Epigallocatechin-3-gallate on Obesity by Suzuki T1, Pervin M2, Goto S3, Isemura M4, Nakamura Y5.(PubMed)
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