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Sunday, February 28, 2021

Tualang Honey Shows a Strong effect in Boosting Memory in Vivo, Researchers Say

Honey may have a profound and positive effect in boosting human memory, some scientists suggested

Memory is a process of the minds in learning and storing information.

Memory impairment is a condition of not remembering the new and current event which may be recalled in a short period of time, affecting mostly the older population.

Memory impairment is an early symptom associated with late-life neurodegenerative diseases.

In contrast to general belief, memory impairment not only is associated with the progression of neurodegenerative diseases but also can be caused by other factors such as medical conditions including stroke and brain injury.

Long-term use of certain medications such as antidepressants, antihistamines, anti-anxiety medications, excessive alcohol drinking, substance abuse, and tobacco are some major risk factors associated with the onset of memory loss.

Some researchers suggested that people who are living under long-term stress and anxiety or follow a nutritionally deficient diet are most vulnerable to the condition develops.

According to the article "Stress might lead to memory loss and brain shrinkage, study says" By Sandee LaMotte, CNN wrote, "If you live a high-stress life, you could have memory loss and brain shrinkage before you turn 50, according to a study published Wednesday in the journal Neurology".

"Higher levels of cortisol, a stress hormone, seem to predict brain function, brain size and performance on cognitive tests," said study author Dr. Sudha Seshadri, professor of neurology at UT Health San Antonio.

"We found memory loss and brain shrinkage in relatively young people long before any symptoms could be seen," Seshadri said. "It's never too early to be mindful of reducing stress."


In other words, long-term stress can induce the production of certain hormones such as cortisol which have strong implications on the brain in the induction of memory loss.

Honey is a miraculous product made by bees using nectar from flowers.

The rich golden liquid It is considered one of healthy sweet food for replacing the use of white sugar and artificial sweetener by many people.

On finding the correlation and association with the aging and stress exposure and memory impairment, researchers examined the potential protective effects of Tualang honey supplementation on memory performance in aged rats exposed to noise stress.

Tested rats were given orally, 200 mg/kg body weight of Tualang honey supplementation for 28 days, before exposing to the loud noise, 100 dB(A), 4 hours daily for 14 days.

Rats subjected to noise stress exhibited significantly lower memory performance and higher oxidative stress, through the increased expression of oxidative stress markers, the elevated malondialdehyde, and protein carbonyl levels.

The stress rats also exhibited a reduction of the levels of antioxidant enzymes compared to the nonstressed rats.

Tualang honey supplementation applied to the stress rats showed a significant improvement of the memory performance, by decreasing oxidative stress levels and increasing the brain-derived neurotrophic factor (BDNF) concentration, which was reduced due to stress.

Furthermore, Tualang honey also normalized the ratio of free radicals and antioxidants in the stress rats body and enhanced neuronal proliferation in the medial prefrontal cortex (mPFC) and hippocampus associated with memory, particularly, in long-term memory.

Dr. Azman KF, the lead scientist at the final report wrote, "Tualang honey protects against memory decline due to stress exposure and/or aging via enhancement of mPFC and hippocampal morphology possibly secondary to a reduction in brain oxidative stress and/or upregulation of BDNF concentration and cholinergic system".

The results underlined the effects of Tualang honey effect in boosting short and long-term memory which was significantly reduced by stress exposure and/or aging.

Moreover, in the study of the total of forty-eight adult male rats randomly divided into the following four groups: i) nonstressed with vehicle, ii) nonstressed with Tualang honey, iii) stressed with vehicle, and iv) stressed with honey with supplement was given once daily via oral gavage at 0.2 g/kg body weight, researchers found that
* The rats subjected to noise stress were found to process higher levels of depressive-like behavior and lower memory functions compared to the unexposed control rats.

* Tuatang honey supplementation regimen successfully counteracted the effects of noise stress.

* Tualng honey also increased the climbing and swimming and mobility times significantly.

These results suggested that Tualang honey normalizes the cognitive function of the rats exposed to noise stress, similar to those of the first study.

Taken altogether, Tualang honey may be considered a functional food for the prevention and combined with the primary therapy for the treatment of cognitive impairment, pending the larger and multicenter's human study.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.

Sources
(1) Tualang Honey Attenuates Noise Stress-Induced Memory Deficits in Aged Rats by Azman KF1, Zakaria R1, Abdul Aziz CB1, Othman Z2. (PubMed)
(2) Tualang honey improves memory performance and decreases depressive-like behavior in rats exposed to loud noise stress by Azman KF1, Zakaria R, AbdAziz C, Othman Z, Al-Rahbi B. (PubMed)
(3) Potential Role of Honey in Learning and Memory by Othman Z1, Zakaria R2, Hussain NHN3, Hassan A4, Shafin N5, Al-Rahbi B6, Ahmad AH. (PubMed)

Friday, February 26, 2021

Green Tea May Be Effective for Reducing the Risk and Treatment of Chronic Obstructive Pulmonary Disease (COPD)

Green tea may be considered as a potential pharmacotherapy for asthma and chronic obstructive pulmonary disease (COPD), a renowned institute study suggested.

Green tea, a precious drink processes numbers of health benefits known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine, or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. Adding a slice of ginger will resolve the problem.

Chronic obstructive pulmonary disease (COPD) is a condition of lung disease caused by obstruction of airflow in normal breathing.

In a total of 13,651 adults from three Dutch cities examined from 1994 to 1997. observation of dietary intake estimated using a food frequency questionnaire, and flavonoid intake calculated using specific food composition tables, showed a significant effect of flavonoid intake regularly in reduced risk COPD.

According to the returned questionnaire, total catechin, flavonol, and flavone intake was positively associated with FEV1 in airflow of a deep breath and inversely associated with chronic cough and breathlessness, common symptoms of chronic obstructive pulmonary disease (COPD).

More specifily, Dr. Tabak C, the lead author said, "Flavonol and flavone intake was independently associated with a chronic cough only"

Furthermore, Chafuroside A (CFA), a water-soluble flavone C-glycoside, isolated from oolong tea, in oral administration exhibited at 0.5mg/kg or higher exhibited a profound effect in attenuated inflammatory symptoms in a dose-dependent manner, in experimental asthma/chronic obstructive pulmonary disease (COPD)-like a model.


In fact, Biomarker profiling revealed that the CFA/SAM at 0.1mg CFA/kg equipotent to CFA at 1.0mg/kg testing result also expressed protective activity against antigen-induced airway inflammation.

Taking together, there is no doubt that green tea may be used as a portion of therapeutic and functional food for reduced risk and treatment of chronic obstructive pulmonary disease (COPD) through the expression of plant phytochemicals, but large amount intake regularly should be taken with care in prevented toxicity.


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months




Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Phytoceuticals: the new 'physic garden' for asthma and chronic obstructive pulmonary disease by Grandhi S1, Donnelly LE, Rogers DF.(PubMed)
(2) Chronic obstructive pulmonary disease and intake of catechins, flavonols, and flavones: the MORGEN Study by Tabak C1, Arts IC, Smit HA, Heederik D, Kromhout D.(PubMed)
(3) Self-assembled micellar formulation of chafuroside A with improved anti-inflammatory effects in experimental asthma/COPD-model rats by Onoue S1, Matsui T, Aoki Y, Ishida H, Nukaya H, Kou K, Yamada S.(PubMed)

Thursday, February 25, 2021

Coffee, A Potential Beverage for Weight Loss and Weight Management?

In compared to herbal medicine, food therapy even takes longer to ease symptoms, depending to stages of the treatment which directly address to the cause of the disease.

Coffee, a popular drink may be an excellent beverage for induced weight loss and weight management, a reviewed study by respectable university revealed.

Coffee, emerging as a popular and social beverage all over the world, particular in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.

Weight loss is an intentional reduction of the total body mass, according to the definition stated by medicine, health, or physical fitness experts.

According to the University of Exeter, in the reviewed data from human clinical trials, differentiated 8 eligible trials, green coffee extract (GCE) have moderated or significant effect in reduced weight loss in compared to placebo.

In the rat model, 48t rats fed with either a control diet with water (C) or a control diet with a coffee solution (CF). At the end of week 4, animals in each dietary group were subdivided into three exercise groups: before exercise (BE), during exercise (DE), and after exercise (AE), the group fed with coffee solution showed a significantly reduced total weight compared diet with water group.

The efficacy of dietary coffee in decreased total weight loss may be attributed to the extract function in stimulating the production of antioxidants in suppressed free radical expression. as well as increasing total cholesterol.

Dr. Choi EY the lead author said, "freeze-dried instant coffee can promote activities of antioxidant enzymes and induce weight loss but also aggravate the plasma cholesterol profile in rats".

Additionally, in the compared the daily consumption of coffee and caffeinated beverages between 494 weight loss maintainers and 2129 individuals from the general population, consumed significantly more cups of coffee are found in the weight loss maintainers than the general population group.

Other researchers insisted that the efficacy of coffee in induced weight loss, probably due to activities of caffeine and other chemical constituents of coffee, such as chlorogenic acid and quinides.


Collective findings suggested that coffee may have a potentially therapeutic property in weight deduction. But some reviewed trials were associated with a high risk of bias. poor methodological quality, therefore, more studies are necessary to confirm the promising validity, some researchers suggested.



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Sources
(1) The use of green coffee extract as a weight-loss supplement: a systematic review and meta-analysis of randomized clinical trials by Onakpoya I1, Terry R, Ernst E.(PubMed)
(2) Caffeine intake is related to successful weight loss maintenance by Icken D1, Feller S2, Engeli S3, Mayr A4, Müller A1, Hilbert A5, de Zwaan M1.(PubMed)
(3) Freeze-dried instant coffee can promote the activities of antioxidant enzymes and induce weight loss but also aggravate the plasma cholesterol profile in rats by Choi EY1, Park SY, Cho YO.(PubMed)
(4) Coffee, diabetes, and weight control by Greenberg JA1, Boozer CN, Geliebter A.(PubMed)
------------------------------------------------------------------------------------------------------------
Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Wednesday, February 24, 2021

Green Tea Reduces the risk of Early onset and Progression of Cognitive Impairment

Green tea injection is associated with reduced risk of age-related cognitive decline, a recent study postulated.

Cognitive impairment is a condition of the decline of memory and thinking skills due to aging considered as an early sign of neurodegenerative diseases.

Green tea, a precious drink processes numbers of health benefits known to almost everyone in Asia and the Western world. However, as yin in nature herbal medicine, or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. Adding a piece of ginger will solve the problem.

In a total of 12 elderly nursing home residents with cognitive dysfunction, participants who drink green tea powder 2 g/day for 3 months showed a significantly improved cognitive performance and reduced the progression of cognitive dysfunction indicated by the Mini-Mental State Examination Japanese version (MMSE-J) score.

Another study (Japanese residents aged >60 years from Nakajima, Japan (the Nakajima Project) of 723 participants with normal cognitive function at a baseline survey (2007-2008), the 490 completed the follow-up survey in 2011-2013, suggested that incidence of dementia and cognitive impairment are lower among individuals who consumed green tea 1-6 days per week compared with individuals who did not consume green tea at all.

Additionally, according to the double-blind, randomized controlled study of 39 nursing home residents with cognitive dysfunction (four men, 29 women) divided into two groups either with
consumption of 2 g/day of green tea powder (containing 220.2 mg of catechins) or placebo powder (containing 0.0 mg of catechins), green tea treated group showed a significantly reduced cognitive dysfunction in 3 months follow up in compared to placebo.

The efficacy of green tea in decreased progression of cognitive impairment in the short term may be attributed to ameliorated oxidative stress and levels of low-density lipoprotein.

Taking together, Green tea may process potential in reduced risk of early-onset and progression of cognitive decline in aging population, but long term and large amount injection should be taken with care.


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months



Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Green tea consumption affects cognitive dysfunction in the elderly: a pilot study by Ide K1, Yamada H2, Takuma N3, Park M4, Wakamiya N5, Nakase J6, Ukawa Y7, Sagesaka YM8.(PubMed)
(2) Consumption of green tea, but not black tea or coffee, is associated with reduced risk of cognitive decline by Noguchi-Shinohara M1, Yuki S1, Dohmoto C1, Ikeda Y1, Samuraki M1, Iwasa K1, Yokogawa M2, Asai K3, Komai K4, Nakamura H5,(PubMed)
(3) Effects of green tea consumption on cognitive dysfunction in an elderly population: a randomized placebo-controlled study by Ide K1, Yamada H2, Takuma N3, Kawasaki Y1, Harada S1, Nakase J4, Ukawa Y4, Sagesaka YM4.(PubMed)

Tuesday, February 23, 2021

Health Food Onion Processes Anti-Atherogenic Property

Atherosclerosis is a condition characterized by the accumulated plaque on the arterial wall. Over time the condition can cause stiffening and hardening of the arteries, leading to cardiovascular disease.

Anti-atherogenic activity is the process to prevent or inhibit atherogenesis associated with the reduced formation of fatty plaques in the arteries.

In other words, anything, including the use of substances such as herbal remedy that prevents the blockage or narrowing of the arteries is considered atheroprotective effects.

Plaque in the arteries is formed by substances including fat, cholesterol, calcium, and other substances found in the blood in the bloodstream. However, most cases of atherosclerosis are also involved in the amount of cholesterol that normally returned to the liver in healthy individuals remaining in the blood due to low levels of good cholesterol (HDL) or overexpression of bad cholesterol (LDL).

In other words, an unhealthy ratio of low and high-density lipoprotein is also one of the major risk factors of atherosclerosis.

The healthy ratio of blood cholesterol is any number that is less than 4 (LDL)/ 1 (HDL).


Some researchers suggested by increasing the levels of good cholesterol in the blood, the risk of atherosclerosis can be reduced.

Dr. Feig JE and colleagues wrote, "Pharmacologic agents, such as fibrates and niacin that increase HDL cholesterol levels have been associated with decreased cardiovascular events and beneficial effects on the coronary and carotid arteries".

And, "...potential mechanisms by which HDL may exert these anti-atherogenic effects, namely through its role in reverse cholesterol transport, its effects on endothelial cells, and its anti-inflammatory/antioxidant activities".

The results strongly suggested a healthy diet including nuts, coffee, cocoa, grapes, and berries with high levels of HLD may have a profound effect on the prevention of atherosclerosis.

The onion is a plant in the genus Allium, belonging to the family Alliaceae, a close relation of garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.

Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild, or sweet.

On finding a potent ingredient that processes cardioprotection researchers examined the quercetin and polyuronide contents of rapidly dried onion (Allium cepa L. cv. Momiji No. 3) powder (OP) prepared from the outer layers (from second to the fourth scale leaves from the surface) of onion bulbs anti-atherogenic effect.

The study included rats fed a high-fat diet treated by quercetin 4'-glucoside (50%), free quercetin (30%) and quercetin 3,4'-glucoside (20%) as quercetin derivatives in boiling-water extraction.

According to the tested differentiation, in high-fat diet Wistar rats, additional OP did not show a significant difference in total cholesterol, HDL-cholesterol and triglyceride concentrations compared to rats fed a high-fat diet without OP.

However, the atherogenic index (AI) associated with cardiovascular disease risk of Wistar rats fed an OP-added high-fat diet was lower compared to those fed with a diet without OP.

Moreover, the incremental elastic modulus (IEM), a measurement of the stiffness of the larger arteries from rats fed the OP-added diet was also significantly lower compared to rats fed by diet without OP.

Additionally, both rat groups were found to exert similar AI and IEM values if the rats fed the diet without OP were allowed spontaneous exercise.

In other words, OP protected the cardio-tissue by exerting an anti-atherogenic effect through other unknown mechanisms associated with regular exercise, without affecting the parameters of cholesterol.

Based on the results, researchers wrote, "These results suggest that OP intake is effective for decreasing the risk of arteriosclerosis".

Taken altogether, onion processed a higher mount of Onionin A (ONA) may be considered a remedy for the prevention and treatment of arteriosclerosis, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Physicochemical characteristics of rapidly dried onion powder and its anti-atherogenic effect on rats fed high-fat diet by Hamauzu Y1, Nosaka T2, Ito F3, Suzuki T4, Torisu S3, Hashida M5, Fukuzawa A6, Ohguchi M3, Yamanaka. (PubMed).
(2) Atheroprotective effects of HDL: beyond reverse cholesterol transport by Feig JE1, Shamir R, Fisher EA. (PubMed)

Monday, February 22, 2021

Fish Oils Process a Positive Effect on Plasma Lipids in Healthy Individuals

Lipid refers to cholesterol and triglycerides.

Hypertriglyceridemia is a health issue associated with abnormally high blood levels triglycerides,
Triglycerides are body fat found in humans derived from glycerol and saturated, monounsaturated, and polyunsaturated fatty acid.

The triglycerides are stored in your fat cells to energy in the future when the body needs them.
if the levels of triglycerides are above 500 mg/dL (above 5.7 mmol/L), you have high blood triglyceride.

Abnormal high levels of triglycerides have been found to induce symptoms of gastrointestinal pain. difficulty breathing, memory loss, dementia and yellowish deposits of fat on or around the eyelids.

Hyperlipidemia is a medical condition of abnormally high levels of cholesterol and fat in the bloodstream.

High blood cholesterol is the most common cause of hyperlipidemia. According to statistics provided by the CDC, more than 12% of adults age 20 and older are living with high blood cholesterol with a total cholesterol higher than 240 mg/dL. and more than 18% had high-density lipoprotein (HDL, or “good”) cholesterol levels less than 40 mg/dL.

In other words, hyperlipidemia has a high prevalent ratio that affects over 100 million Americans and the condition is increasing at an alarming rate due to overweight and obesity.

Believe it or not, only half of the people with high blood cholesterol benefit from taking the lowering blood cholesterol medicine.

Cholesterol produced by the liver and absorbed through diet to build cell walls, produce steroid hormone and vitamin D and aid digestive, the primary of triglycerides function is to store as unused calories and provide your body with energy.


The healthy ratio of low-density lipoprotein (LDL)/high-density lipoprotein (HDL) is ant numbers that are less than 4.

Fish oil derived from the tissues of fishes, containing a high amount of the omega-3 fatty acids.
The three main components of omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of chronic disease, researchers launch a first-in-human trial of LCMUFA-rich saury fish oil supplementation effect on plasma lipids.

The double-blind, randomized, crossover clinical trial included 30 healthy normolipidemic adults (BMI <25 kg/m2; mean TG, 84 mg/dL) who were treated by either 12 g of sauredy oil (3.5 g of LCMUFA and 3.4 g of omega-3 FAs) or identical capsules with control oil (a mixture of sardine and olive oil; 4.9 g of shorter-chain MUFA oleate and 3 g of omega-3 FAs).

According to the results, saury oil supplementation was safe and resulted in LDL particle counts 12% lower than control oil.

On a linear mixed effect model, saury oil also showed a minor effect on increasing HDL particle size (9.8 nm vs 9.7 nm; P < .05), compared to the control oil which increased LDL-C by only 7.5% compared with baseline.

Most importantly, saury oil exerted similar effects compared to control oil on lowering plasma TG levels, VLDL, and TG-rich lipoprotein particle counts (by ∼16%, 25%, and 35%, respectively; P < .05), and increasing HDL-C and cholesterol efflux capacity (by ∼6% and 8%, respectively; P < .05) compared with baseline.


Based on the findings, researchers said, "Saury oil supplementation is well tolerated and has beneficial effects on several cardiovascular parameters, such as LDL particle counts, HDL particle size, and plasma TG levels".

Taken altogether, fish oil may be considered a functional food for the protection of cardiovascular parameters, pending to the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Supplementation with saury oil, a fish oil high in omega-11 monounsaturated fattyacids, improves plasma lipids in healthy subjects by Yang ZH1, Amar M2, Sorokin AV2, Troendle J3, Courville AB4, Sampson M5, Playford MP6, Yang S4, Stagliano M2, Ling C5, Donkor K2, Shamburek RD2, Mehta NN6, Remaley AT. (PubMed)

hypertriglyceridemia
(1) Recent developments in pharmacotherapy for hypertriglyceridemia: what's the current state of the art? by Florentin M1, Kostapanos MS2, Anagnostis P3, Liamis G. (PubMed)

Sunday, February 21, 2021

Healthy Food Onion May Process Neuro-Protective Activity

Neuroprotection is a process to preserve the neuronal structure and/or function against the death or gradual death of neurons, including the use of medicines and herbs.

In other words, neuroprotection protects the neuronal integrity against the reduction in the rate of neuronal loss over time inducing neurological disease, including neurodegenerative disease.

Neurodegenerative disease is the class of condition associated with the progressive loss of neurons occurred mostly in older adults, including dementia. The most common dementia in the US is Alzheimer`s disease (AD).

Alzheimer's disease is an irreversible, progressive brain disorder caused by the slowly lost of neuron in the brain that affects the memory and thinking skills and, eventually, the ability to carry out the simplest tasks as the disease progress into advanced stage.


According to the statistic, dementia affects over 47.5 million people worldwide, approximately 58 percent are living within low and middle-income countries.

Believe it or not, 5.8 million Americans of all ages are living with Alzheimer's dementia in 2019, and two-thirds of people with Alzheimer's disease are women.

Conventionally, as of today, there is no cure for dementia. Treatment of dementia is focusing to improve dementia symptoms and slow down the progression of the disease.

Some researchers suggested that the increased incidence of the onset of Alzheimer's disease over the past few decades may be correlated to the promotion of a high-fat diet in the US.

Dr. Rollins CPE, the lead scientist wrote, "HFD-induced obesity during adolescence exacerbated brain volume alterations by adult life in the 3xTg mouse model in comparison to control-fed mice and mediated volumetric alterations of select brain regions, such as the hippocampus".

And, "Further, HFD-induced obesity aggravated memory in all mice, lowering certain memory measures of B6129s control mice to the level of 3xTg mice maintained on a CD. Moreover, a decline in the volumetric trajectories of hippocampal regions for all mice was associated with the degree of spatial memory impairments on the MWM.".

The onion is a plant in the genus Allium, belonging to the family Alliaceae, a close relation of garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.

Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild, or sweet.

On finding a potential compound for the treatment of cognitive impairment, researchers examined the neuroprotective potential of Allium cepa (A. cepa, Onion) in aluminum chloride induced animal model neurotoxicity.


The study included mice-induced neurotoxicity by aluminum chloride (50 mg/kg/day) orally was treated by supplemented with different doses of A. cepa hydroethanolic extract for a period of 60 days.

Before treatment of onion, aluminum chloride treated mice resulted in significant motor incoordination and memory deficits, observed by the increased oxidative stress and elevated levels of acetylcholinesterase (AChE) and aluminum levels in the brain.

Onion supplement injection in aluminum exposed animals not only significantly improved muscle coordination and memory deficits but also decreased the levels of oxidative stress, AChE, and decreased abnormal aluminum deposition induced by the aluminum chloride.

Decreased vacuolated cytoplasm associated with the death of neurons and pyramidal cells in the hippocampal area of the mice brain caused by toxicity was also reversed by the injection of A. cepa supplementation.

The results strongly suggested that onion processes anti-neuro-toxicity induced cognitive impairment in an animal model.

Dr. Singh T, the lead scientist, after taking other factors into account wrote, "significant neuroprotective potential of A. cepa in aluminum-induced neurotoxicity".

Taken altogether, onion may be considered a neuroprotective remedy, pending the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Neuroprotective effect of Allium cepa L. in aluminium chloride induced neurotoxicity by Singh T1, Goel RK. (PubMed)
(2) Protective effects of onion-derived quercetin on glutamate-mediated hippocampal neuronal cell death by Yang EJ1, Kim GS, Kim JA, Song KS. (PubMed)
(3) Contributions of a high-fat diet to Alzheimer's disease-related decline: A longitudinal behavioural and structural neuroimaging study in mouse models by Rollins CPE1, Gallino D2, Kong V3, Ayranci G2, Devenyi GA4, Germann J2, Chakravarty MM. (PubMed)