Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Bowel cancer
Bowel cancer also known as colorectal cancer, is defined as a condition of the abnormal proliferation of cells in the colon, rectum, or vermiform appendix. Bowl is divided in 2 parts, the first part of the bowel, the small bowl, is involved with the digestion and absorption of food. The 2nd part, the large bowel which consist the the colon and rectum, is involved in absorption of water from the small bowel contents and broken down of certain materials in the feces into substances of which some of them to be re absorbed and reused by the body. Bowel cancer is relatively very common and slowly growing and progress cancer and in predictable way.
Bowel cancer is the third most commonly diagnosed cancer in developed countries, particular to women age 50 or older.
Bowel cancer also known as colorectal cancer, is defined as a condition of the abnormal proliferation of cells in the colon, rectum, or vermiform appendix. Bowl is divided in 2 parts, the first part of the bowel, the small bowl, is involved with the digestion and absorption of food. The 2nd part, the large bowel which consist the the colon and rectum, is involved in absorption of water from the small bowel contents and broken down of certain materials in the feces into substances of which some of them to be re absorbed and reused by the body. Bowel cancer is relatively very common and slowly growing and progress cancer and in predictable way.
Bowel cancer is the third most commonly diagnosed cancer in developed countries, particular to women age 50 or older.
The Causes and Risk factors of Inherited Syndromes
Genetic syndromes passed through generations can increase the risk of developing colon cancer.a. Familial adenomatous polyposis (FAP):
Familial adenomatous polyposis is an inherited condition in which numbers of benign polyp form mainly in the lining of the large intestine, but they can become malignant due to the mutations in the APC gene that a patient inherits from the parents.
b. Hereditary non-polyposis colon cancer (HNPCC)
HNPCC is also known as Lynch syndrome. It can increase the risk of developing bowel cancer than the general population due to mutation of genes in repairing DNA damage.
c. Turcot syndrome
Turcot syndrome is also a rare inherited condition in which cells become abnormal and form multiple adenomatous colon polyps anf eventually turn malignant.
d. Peutz-Jeghers syndrome
Peutz-Jeghers syndrome is an autosomal dominant genetic disease with condition of the development of benign hamartomatous polyps in the gastrointestinal tract and hyperpigmented macules on the lips and oral mucosa due to mutations in the gene STK1.
e. MUTYH-associated polyposis
MUTYH is a human gene encoding a DNA glycosylase. Mutations in the gene MUTYH increases the risk of develop colon polyps which eventually become cancerous if the colon is not removed.
Genetic syndromes passed through generations can increase the risk of developing colon cancer.a. Familial adenomatous polyposis (FAP):
Familial adenomatous polyposis is an inherited condition in which numbers of benign polyp form mainly in the lining of the large intestine, but they can become malignant due to the mutations in the APC gene that a patient inherits from the parents.
b. Hereditary non-polyposis colon cancer (HNPCC)
HNPCC is also known as Lynch syndrome. It can increase the risk of developing bowel cancer than the general population due to mutation of genes in repairing DNA damage.
c. Turcot syndrome
Turcot syndrome is also a rare inherited condition in which cells become abnormal and form multiple adenomatous colon polyps anf eventually turn malignant.
d. Peutz-Jeghers syndrome
Peutz-Jeghers syndrome is an autosomal dominant genetic disease with condition of the development of benign hamartomatous polyps in the gastrointestinal tract and hyperpigmented macules on the lips and oral mucosa due to mutations in the gene STK1.
e. MUTYH-associated polyposis
MUTYH is a human gene encoding a DNA glycosylase. Mutations in the gene MUTYH increases the risk of develop colon polyps which eventually become cancerous if the colon is not removed.
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