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Wednesday, May 28, 2014

Garlic and Cervical Cancer

 Posted by Chantel Martiromo 

Cervical cancer is malignant neoplasm of the cervix uteri or cervical area caused by abnormal cells growth with alternation of cells DNA. According to the American Cancer Society's, in 2014, 12,360 new cases of invasive cervical cancer will be diagnosed with the death of  4,020 patients. The risk of cervical cancer is higher in Hispanic women followed by African-Americans, Asians and Pacific Islanders, and whites(a).
Depending to the stage and grade of the cancer, if the cancer is found in the early stahe, hysterectomy may not be needed. Other while  after sugery, chemotherapy including Cisplatin, Fluorouracil (5-FU), Mitomycin, Paclitaxel, Ifosfamide, Carboplatin, Bevacizumab and radiotherapy may be necesary, but with certain side effects. Emerging suggestion of a healthy and balanced diet to improve high serum levels of antioxidants may reduce cervical neoplasia risk(b)(c)  but other suggested that the role of diet and nutrition in the etiology of cervical cancer is not yet resolved(d) and Catalan Institute of Oncology study showed statistically nonsignificant inverse associations were also observed for leafy vegetables, root vegetables, garlic and onions, citrus fruits, vitamin C, vitamin E and retinol for invasive squamous cervical cancer (ISC)(e).
Epidemiological studies, linking herbal medicine in reduced risk of cervical cancer have not been consistent. But certain herbs and spice may be effective in  treating cervical caner(1) with little or no side effects.
Garlic (Allium sativum) is a species in the onion genus, belonging to family Amaryllidaceae, native to central Asia. It has been used popularly in traditional and Chinese medicine in treating common cold and flu to the Plague, blood pressure cholesterol levels, natural antibiotic, etc.
Diallyl sulfide (DAS), a chemical component of garlic induced mitochondrial dysfunction, leading to the release of cytochrome c for causing apoptosis in human cervical cancer Ca Ski cells(21) and cell cycle arrest and apoptosis through the p53, caspase- and mitochondria-dependent pathways in in HeLa human cervical cancer cells(22). The Defense Food Research Laboratory study indicated that Garlic exerted its anticarcinogenic effect(including cervical cancer) through a number of mechanisms, including scavenging of radicals, increasing gluathione levels, increasing the activities of enzymes(23). In 3-methylcholanthrene (MCA)-induced carcinogenesis in the uterine cervix of virgin young adult Swiss albino mice study, found a significant decline in the incidence of carcinoma with oral administration of garlic at the dose level of 400 mg/kg body wt./day for 2 weeks before and 4 weeks following carcinogen thread insertion(24).
Chinese Secrets to Fatty Liver and Obesity Reversal
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References
(a) Cerical cancer (Amerrican cancer society)
(b) Diet and serum micronutrients in relation to cervical neoplasia and cancer among low-income Brazilian women by Tomita LY1, Longatto Filho A, Costa MC, Andreoli MA, Villa LL, Franco EL, Cardoso MA; Brazilian Investigation into Nutrition and Cervical Cancer Prevention (BRINCA) Study Team.(PubMed)
(c) Associations of dietary dark-green and deep-yellow vegetables and fruits with cervical intraepithelial neoplasia: modification by smoking by Tomita LY1, Roteli-Martins CM, Villa LL, Franco EL, Cardoso MA; BRINCA Study Team.(PubMed)
(d) Diet and the risk of in situ cervical cancer among white women in the United States by Ziegler RG1, Jones CJ, Brinton LA, Norman SA, Mallin K, Levine RS, Lehman HF, Hamman RF, Trumble AC, Rosenthal JF, et al.(PubMed)
(e) Dietary factors and in situ and invasive cervical cancer risk in the European prospective investigation into cancer and nutrition study by González CA1, Travier N, Luján-Barroso L, Castellsagué X, Bosch FX, Roura E, Bueno-de-Mesquita HB, Palli D, Boeing H, Pala V, Sacerdote C, Tumino R, Panico S, Manjer J, Dillner J, Hallmans G, Kjellberg L, Sanchez MJ, Altzibar JM, Barricarte A, Navarro C, Rodriguez L, Allen N, Key TJ, Kaaks R, Rohrmann S, Overvad K, Olsen A, Tjønneland A, Munk C, Kjaer SK, Peeters PH, van Duijnhoven FJ, Clavel-Chapelon F, Boutron-Ruault MC, Trichopoulou A, Benetou V, Naska A, Lund E, Engeset D, Skeie G, Franceschi S, Slimani N, Rinaldi S, Riboli E.(PubMed)

(21) Diallyl sulfide promotes cell-cycle arrest through the p53 expression and triggers induction of apoptosis via caspase- and mitochondria-dependent signaling pathways in human cervical cancer Ca Ski cells by Chiu TH1, Lan KY, Yang MD, Lin JJ, Hsia TC, Wu CT, Yang JS, Chueh FS, Chung JG.(PubMed)
(22) Diallyl sulfide induces cell cycle arrest and apoptosis in HeLa human cervical cancer cells through the p53, caspase- and mitochondria-dependent pathways by Wu PP1, Chung HW, Liu KC, Wu RS, Yang JS, Tang NY, Lo C, Hsia TC, Yu CC, Chueh FS, Lin SS, Chung JG.(PubMed)
(23) Anticarcinogenic properties of garlic: a review by Khanum F1, Anilakumar KR, Viswanathan KR.(PubMed)
(24) Chemopreventive action of garlic on methylcholanthrene-induced carcinogenesis in the uterine cervix of mice by Hussain SP1, Jannu LN, Rao AR.(PubMed)

Blue Cheese Cut-Out Crackers

Posted by Chantel Martiromo 
Recipe by Quick and easy family favorites (by Vickie and JoAnn)

These delicate cheese wafers carry a touch of hot pepper... but you can season to your own taste.
1 c. all purpose flour
7 T. crumbled blue cheese
1 egg yolk
4 t. whipping cream
7 T. butter, softened
1/2 dried parsley
1/8 tsp. salt
cayenne pepper tto taste
Mix all ingredients in a bowl; let rest for 80 minutes. Roll dough out to 1/8 inch thickness. Use your favorite cookie cutter shapes to cut out the crackers. bake on ungreased baking sheet at 400 degrees
for 8 to 10 minutes or just until golden. Carefully remove the delicate crackers when cool.
Make 11/2 to 2 dozen.
Chinese Secrets to Fatty Liver and Obesity Reversal
A fabulous E book with Research based & Scientifically proven Efficacy To Treat Fatty Liver Diseases & Achieve Optimal Health & Loose Weight
 
Ovarian Cysts And PCOS Elimination
 Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months  


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Tuesday, May 27, 2014

Aloe vera and Cervical Cancer

   Posted by Chantel Martiromo 

Cervical cancer is malignant neoplasm of the cervix uteri or cervical area caused by abnormal cells growth with alternation of cells DNA. According to the American Cancer Society's, in 2014, 12,360 new cases of invasive cervical cancer will be diagnosed with the death of  4,020 patients. The risk of cervical cancer is higher in Hispanic women followed by African-Americans, Asians and Pacific Islanders, and whites(a).
Depending to the stage and grade of the cancer, if the cancer is found in the early stahe, hysterectomy may not be needed. Other while  after sugery, chemotherapy including Cisplatin, Fluorouracil (5-FU), Mitomycin, Paclitaxel, Ifosfamide, Carboplatin, Bevacizumab and radiotherapy may be necesary, but with certain side effects. Emerging suggestion of a healthy and balanced diet to improve high serum levels of antioxidants may reduce cervical neoplasia risk(b)(c)  but other suggested that the role of diet and nutrition in the etiology of cervical cancer is not yet resolved(d) and Catalan Institute of Oncology study showed statistically nonsignificant inverse associations were also observed for leafy vegetables, root vegetables, garlic and onions, citrus fruits, vitamin C, vitamin E and retinol for invasive squamous cervical cancer (ISC)(e).
Epidemiological studies, linking herbal medicine in reduced risk of cervical cancer have not been consistent. But certain herbs and spice may be effective in  treating cervical caner(1) with little or no side effects.
Aloe vera
Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It has become very popular for commercial cultivation due to its health benefits. Aloe vera has been used in herbal medicine in treating many kinds of disease, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated of cholesterol, etc. It is also one of many popular herbs studied in scientific ways with some conflicted results.
Aloe emodin, a major chemical constituent of Aloe vera, inhibited the growth of human cervical cancer cell line, HeLa cells in a dose-dependent manner, through cycle arrest and decreased cyclin A and CDK2, and increased in cyclin B1 and CDK1expression(13). Aloin, another chemical compound from the herb, exerted a pronounced antiproliferative effect through cell cycle arrest in the S phase and induced increased HeLaS3 cell apoptosis(14). Rhein-aloe-emodin hybrid molecule (RH-AE), a synthetic version of from rhein and aloe-emodin, inhibited the human ovarian cancer SK-OV-3 in lesser effective than those of rhein and aloe-emodin(15).
Chinese Secrets to Fatty Liver and Obesity Reversal
A fabulous E book with Research based & Scientifically proven Efficacy To Treat Fatty Liver Diseases & Achieve Optimal Health & Loose Weight
 
Ovarian Cysts And PCOS Elimination
 Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months  


Back to Tofu and 600+ healthy recipe  http://thetruestoriesstories.blogspot.ca/p/soy-recipes.html
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References
(a) Cerical cancer (Amerrican cancer society)
(b) Diet and serum micronutrients in relation to cervical neoplasia and cancer among low-income Brazilian women by Tomita LY1, Longatto Filho A, Costa MC, Andreoli MA, Villa LL, Franco EL, Cardoso MA; Brazilian Investigation into Nutrition and Cervical Cancer Prevention (BRINCA) Study Team.(PubMed)
(c) Associations of dietary dark-green and deep-yellow vegetables and fruits with cervical intraepithelial neoplasia: modification by smoking by Tomita LY1, Roteli-Martins CM, Villa LL, Franco EL, Cardoso MA; BRINCA Study Team.(PubMed)
(d) Diet and the risk of in situ cervical cancer among white women in the United States by Ziegler RG1, Jones CJ, Brinton LA, Norman SA, Mallin K, Levine RS, Lehman HF, Hamman RF, Trumble AC, Rosenthal JF, et al.(PubMed)
(e) Dietary factors and in situ and invasive cervical cancer risk in the European prospective investigation into cancer and nutrition study by González CA1, Travier N, Luján-Barroso L, Castellsagué X, Bosch FX, Roura E, Bueno-de-Mesquita HB, Palli D, Boeing H, Pala V, Sacerdote C, Tumino R, Panico S, Manjer J, Dillner J, Hallmans G, Kjellberg L, Sanchez MJ, Altzibar JM, Barricarte A, Navarro C, Rodriguez L, Allen N, Key TJ, Kaaks R, Rohrmann S, Overvad K, Olsen A, Tjønneland A, Munk C, Kjaer SK, Peeters PH, van Duijnhoven FJ, Clavel-Chapelon F, Boutron-Ruault MC, Trichopoulou A, Benetou V, Naska A, Lund E, Engeset D, Skeie G, Franceschi S, Slimani N, Rinaldi S, Riboli E.(PubMed)

(13) Anticancer effect of aloe-emodin on cervical cancer cells involves G2/M arrest and induction of differentiation by Guo JM1, Xiao BX, Liu Q, Zhang S, Liu DH, Gong ZH.(PubMed)
(14) Antitumor effects of a natural anthracycline analog (Aloin) involve altered activity of antioxidant enzymes in HeLaS3 cells by Nićiforović A1, Adzić M, Spasić SD, Radojcić MB.(PubMed)
(15) Synthesis and anti-tumor activity evaluation of rhein-aloe emodin hybrid molecule by Yuan YF1, Hu XY, He Y, Deng JG.(PubMed)
 

Tomato-Bacon Nibbles

   Posted by Chantel Martiromo 
Recipe by Quick and easy family favorites (by Vickie and JoAnn)
A 1/4 teaspoon measuring spoon is just right for scooping out tiny tomatoes for stuffing.
24 to 30 cherry tomatoes
16 oz. pkg. bacon crispy cooked and crumbled
2 T. fresh parsley chopped
1/2 cup green onions finely chopped
3 T. grated parmesan cheese
1/2 cup mayonnaise
Cut a thin slice off the top of each tomatoes and if desired, cut a thin slice from bottom of each tomatoes( so the tomatoes will stand up right); scoop out and discard tomato pulp. Place tomatoes upside-down on a paper towel to drain for 10 minutes.
Mix bacon and remaining 4 ingredients in a small bowl, stuff tomatoes. Serve immediately or chill up to 2 hours. Make 2 to 21/2 dozen.
Chinese Secrets to Fatty Liver and Obesity Reversal
A fabulous E book with Research based & Scientifically proven Efficacy To Treat Fatty Liver Diseases & Achieve Optimal Health & Loose Weight
 
Ovarian Cysts And PCOS Elimination
 Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months  


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Monday, May 26, 2014

Free radical scavengers Vitamin C and Skin Lightening (Whitening)

Posted by Chantel Martiromo  

Human skin pigmentation is the result of natural selection evolved to prevent damage to skin through regulation of ultraviolet radiated penetration depending to the production of melanin in the skin cells.
1. Hypo-pigment
a. Vitiligo is defined as a condition of destruction of cells that give your skin its color, causing white patches on your skin.
b. Albinism is a congenital disorder causes of complete or partial absence of pigment in the skin, hair and eyes as a result of restriction of the skin cells from producing melanin
2.Hyper pigment is a result of over production of pigments of certain cells in the skin, causing skin darkening in some area, such as tan or brown patches, commonly on the facial skin
3. Skin discoloring is a result of discoloring your skin in specific spots or very widespread
4. Chloasma is the appearance of brown patches of pigmentation on the forehead, cheeks, and neck
due to hormonal change during pregnancy.
5. Melasma happens to women who have fluctuation of hormones, are taking birth control pills and certain medications. with brownish-grayish patches on the skin, most often on the cheek.

 Free radical scavengers Vitamin C
Suggestions of antioxidants, may be next potential agent in inhibition of tyrosinase activity and reduction of the melanin content in cells(22)(22a)
 Vitamin C Vitamin C also known as L-ascorbic acid, is a water-soluble vitamin, found in fresh fruits, berries and green vegetables. It is best known for its free radical scavengers activity and regenerating oxidized vitamin E for immune support.
Ascorbic acid (AA) has been well known as a skin whitening agent, according to the Mahidol University, AA showed to inhibit UVA-mediated catalase (CAT) inactivation, glutathione (GSH) depletion, oxidant formation and NO production through suppression of eNOS and iNOS mRNA via its antioxidant defense(23). In the comparison of orchid extracts and 3% vitamin C derivative formulated, researchers at the Osaka National Hospital, National Hospital Organizationfound that the orchid-rich plant extracts possess efficacy similar to vitamin C derivative in whitening the skin as well as melasma and lentigo senilis on the face of Japanese women(24). Other study suggested that topical application of the composition of L(+) lactic acid supplemented with ascorbic acid (1%) produced a whitening effect and a modest preferential lightening of age spots which becomes apparent after three months, through demonstrated clinically by the test panelists, and trained clinicians, and with objective instrumental methods(25).
Chinese Secrets to Fatty Liver and Obesity Reversal
A fabulous E book with Research based & Scientifically proven Efficacy To Treat Fatty Liver Diseases & Achieve Optimal Health & Loose Weight
 
Ovarian Cysts And PCOS Elimination
 Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months  


Back to Tofu and 600+ healthy recipe  http://thetruestoriesstories.blogspot.ca/p/soy-recipes.html
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References
(a) Tyrosinase modulation by five Rwandese herbal medicines traditionally used for skin treatment by Kamagaju L1, Morandini R, Bizuru E, Nyetera P, Nduwayezu JB, Stévigny C, Ghanem G, Duez P.(PubMed)
(b) An ethnobotanical survey of medicinal plants used in Rwanda for voluntary depigmentation by Kamagaju L1, Bizuru E, Minani V, Morandini R, Stévigny C, Ghanem G, Duez P.(PubMed)
(c) Tyrosinase inhibition by extracts and constituents of Sideroxylon inerme L. stem bark, used in South Africa for skin lightening by Momtaz S1, Mapunya BM, Houghton PJ, Edgerly C, Hussein A, Naidoo S, Lall N.(PubMed))
 


(22) Biofunctional Constituents from Liriodendron tulipifera with Antioxidants and Anti-Melanogenic Properties by Li WJ1, Lin YC, Wu PF, Wen ZH, Liu PL, Chen CY, Wang HM.(PubMed)
(22a) The effects of areca catechu L extract on anti-inflammation and anti-melanogenesis by Lee KK1, Choi JD.(PubMed)
(23) Inhibition of UVA-mediated melanogenesis by ascorbic acid through modulation of antioxidant defense and nitric oxide system by Panich U1, Tangsupa-a-nan V, Onkoksoong T, Kongtaphan K, Kasetsinsombat K, Akarasereenont P, Wongkajornsilp A.(PubMed)
(24) \Whitening efficacy of plant extracts including orchid extracts on Japanese female skin with melasma and lentigo senilis by Tadokoro T1, Bonté F, Archambault JC, Cauchard JH, Neveu M, Ozawa K, Noguchi F, Ikeda A, Nagamatsu M, Shinn S.(PubMed)
(25) The effects of topical l(+) lactic Acid and ascorbic Acid on skin whitening by Smith WP.(PubMed)

Turmeric and Cervical Cancer

   Posted by Chantel Martiromo 

Cervical cancer is malignant neoplasm of the cervix uteri or cervical area caused by abnormal cells growth with alternation of cells DNA. According to the American Cancer Society's, in 2014, 12,360 new cases of invasive cervical cancer will be diagnosed with the death of  4,020 patients. The risk of cervical cancer is higher in Hispanic women followed by African-Americans, Asians and Pacific Islanders, and whites(a).
Depending to the stage and grade of the cancer, if the cancer is found in the early stahe, hysterectomy may not be needed. Other while  after sugery, chemotherapy including Cisplatin, Fluorouracil (5-FU), Mitomycin, Paclitaxel, Ifosfamide, Carboplatin, Bevacizumab and radiotherapy may be necesary, but with certain side effects. Emerging suggestion of a healthy and balanced diet to improve high serum levels of antioxidants may reduce cervical neoplasia risk(b)(c)  but other suggested that the role of diet and nutrition in the etiology of cervical cancer is not yet resolved(d) and Catalan Institute of Oncology study showed statistically nonsignificant inverse associations were also observed for leafy vegetables, root vegetables, garlic and onions, citrus fruits, vitamin C, vitamin E and retinol for invasive squamous cervical cancer (ISC)(e).
Epidemiological studies, linking herbal medicine in reduced risk of cervical cancer have not been consistent. But certain herbs and spice may be effective in  treating cervical caner(1) with little or no side effects.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia. The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
Curcumin, a polyphenol extracted from turmeric, decreased survival after IR in HeLa cells via induced increased reactive oxygen species (ROS), sustained activation of ERK1/2(9). Human MDR-1 gene expression in multidrug resistant human cervical carcinoma cell line was inhibited by bisdemethoxycurcumin  isolated from turmeric(10). Other extract NBFR-03,, exhibited a arrest low-grade squamous intraepithelial neoplasia (LSIL) a 12 week(11). according to the effect of curcumin on HPV-positive and negative cervical cancer cell lines HeLa, SiHa, CaSki, and C33A pretreated with estradio, conducted by All India Institute of Medical Science, showed a positive effects of curcumin in counteracted the proliferative response of estradiol, and induce apoptosis(12).
Chinese Secrets to Fatty Liver and Obesity Reversal
A fabulous E book with Research based & Scientifically proven Efficacy To Treat Fatty Liver Diseases & Achieve Optimal Health & Loose Weight
 
Ovarian Cysts And PCOS Elimination
 Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months  


Back to Tofu and 600+ healthy recipe  http://thetruestoriesstories.blogspot.ca/p/soy-recipes.html
Back to my Home page at http://thetruestoriesstories.blogspot.ca/     

References
(a) Cerical cancer (Amerrican cancer society)
(b) Diet and serum micronutrients in relation to cervical neoplasia and cancer among low-income Brazilian women by Tomita LY1, Longatto Filho A, Costa MC, Andreoli MA, Villa LL, Franco EL, Cardoso MA; Brazilian Investigation into Nutrition and Cervical Cancer Prevention (BRINCA) Study Team.(PubMed)
(c) Associations of dietary dark-green and deep-yellow vegetables and fruits with cervical intraepithelial neoplasia: modification by smoking by Tomita LY1, Roteli-Martins CM, Villa LL, Franco EL, Cardoso MA; BRINCA Study Team.(PubMed)
(d) Diet and the risk of in situ cervical cancer among white women in the United States by Ziegler RG1, Jones CJ, Brinton LA, Norman SA, Mallin K, Levine RS, Lehman HF, Hamman RF, Trumble AC, Rosenthal JF, et al.(PubMed)
(e) Dietary factors and in situ and invasive cervical cancer risk in the European prospective investigation into cancer and nutrition study by González CA1, Travier N, Luján-Barroso L, Castellsagué X, Bosch FX, Roura E, Bueno-de-Mesquita HB, Palli D, Boeing H, Pala V, Sacerdote C, Tumino R, Panico S, Manjer J, Dillner J, Hallmans G, Kjellberg L, Sanchez MJ, Altzibar JM, Barricarte A, Navarro C, Rodriguez L, Allen N, Key TJ, Kaaks R, Rohrmann S, Overvad K, Olsen A, Tjønneland A, Munk C, Kjaer SK, Peeters PH, van Duijnhoven FJ, Clavel-Chapelon F, Boutron-Ruault MC, Trichopoulou A, Benetou V, Naska A, Lund E, Engeset D, Skeie G, Franceschi S, Slimani N, Rinaldi S, Riboli E.(PubMed)
 
(11) Chemopreventive potential and safety profile of a Curcuma longa extract in women with cervical low-grade squamous intraepithelial neoplasia by Joshi JV1, Paradkar PH, Jagtap SS, Agashe SV, Soman G, Vaidya AB.(PubMed) 
(12) Curcumin counteracts the proliferative effect of estradiol and induces apoptosis in cervical cancer cells by Singh M1, Singh N.(PubMed)

Party Tortilla Wraps

Posted by Chantel Martiromo   

Recipe by Quick and easy family favorites (by Vickie and JoAnn)
Once your kids get a taste of these crispy bites, they'll forgo the fast-food version!
Talk about versatile. These wraps are a great go-to for a tasty appetizer. a special treat for the lunch box or a handy afternoon snack.
8 oz. container chive cream cheese
4(10 inches) flour tortillas
1 Lb. sliced cooked ham
8 oz. pkg. shredded American cheese
Spread craem cheese evenly over tortillas. Place several slices of ham on each tortilla, sprinkle with shredded cheese
Roll up tortillas. Place in refrigerator for 15 minutes. Cut into one-inch piece. make 40 appetizers.

Manly Hardy
Middleville, MI
Chinese Secrets to Fatty Liver and Obesity Reversal
A fabulous E book with Research based & Scientifically proven Efficacy To Treat Fatty Liver Diseases & Achieve Optimal Health & Loose Weight
 
Ovarian Cysts And PCOS Elimination
 Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months  


Back to Tofu and 600+ healthy recipe  http://thetruestoriesstories.blogspot.ca/p/soy-recipes.html
Back to my Home page at http://thetruestoriesstories.blogspot.ca/