Posted by Chantel M. Contributed by US National Library of Medicine National Institutes of Health
In the investigation of "Soy food intake and breast cancer survival" by Shu XO, Zheng Y, Cai H, Gu K, Chen Z, Zheng W, Lu W., , posted in US National Library of Medicine National Institutes of Health, researchers found that During the median follow-up of 3.9 years (range, 0.5-6.2 years), 444
deaths and 534 recurrences or breast cancer-related deaths were
documented in 5033 surgically treated breast cancer patients. Soy food intake, as measured by either soy protein or soy isoflavone intake, was inversely associated with mortality and recurrence. The hazard ratio associated with the highest quartile of soy protein intake
was 0.71 (95% confidence interval [CI], 0.54-0.92) for total mortality
and 0.68 (95% CI, 0.54-0.87) for recurrence compared with the lowest
quartile of intake.
The multivariate-adjusted 4-year mortality rates were 10.3% and 7.4%,
and the 4-year recurrence rates were 11.2% and 8.0%, respectively, for
women in the lowest and highest quartiles of soy protein intake.
The inverse association was evident among women with either estrogen
receptor-positive or -negative breast cancer and was present in both
users and nonusers of tamoxifen.
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