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Endometriosis
During the last stage of the menstrual cycle, normally a layer of endometriosis lining on the inside of the uterus is expelled, known as menstruation blood, instead some of the endometriosis tissues grow somewhere in the body to cause endometriosis. Endometriosis also react to hormone signals of the monthly menstrual cycle, by building and breaking up tissues and eliminating them through menstrual period.
The Symptoms
1. Severe period pain
It normally happens with over-production of prostaglandins and leukotrient causing the cervix to contract resulting in no escape for the menstrual period(1)(2).
During the last stage of the menstrual cycle, normally a layer of endometriosis lining on the inside of the uterus is expelled, known as menstruation blood, instead some of the endometriosis tissues grow somewhere in the body to cause endometriosis. Endometriosis also react to hormone signals of the monthly menstrual cycle, by building and breaking up tissues and eliminating them through menstrual period.
1. Severe period pain
It normally happens with over-production of prostaglandins and leukotrient causing the cervix to contract resulting in no escape for the menstrual period(1)(2).
2. Difficult to get pregnant
If the cyst is presented in the ovary, it will respond to hormone changes in the menstrual cycle causing the cysts to get large every month blocking the normal function of ovaries resulting in infertility(3)(4).
3. Affects patients physically, psychologically and sexually
If endometrosis occurs at the region that is stimulated during sex it may cause excessive pain such as uterosacral ligament and cervical region(5)(6).
4. Chronical pelvic pain and Pain elevate to ward the end of period.
Endometriosis located somewhere other than in the uterus rupturing during menstruation. Since the blood cannot escape, it retents in our body causing damage to the organs or any part of the body hosting the endometriosis resulting in severe pain toward the end of the period(7)(8). Pain on one side of the pelvic during menstrual cycle may be caused by endometrial implants or adhesion to that side of the pelvic.
5. Constipation
Constipation is caused by endometrial implants or adhesion attaching to the organ of excretion. It makes it extremely painful to urinate and defecate(9).
6. Premenstrual dysphoric syndrome
Premenstrual dysphoric syndrome, a severe type of PMS, is defined to have menstrual cramps before and during menstrual cycle. If the pain is more severe than before than it may be caused by endometrial implants or adhesion to more sensitive areas.(10).
7. Heavy period
Heavy period is either caused by menorrhagia or endometriosis. Any women who has never experience heavy period before, the sudden change of heavy period may be caused by the rupturing of the endometrial lining embedded on the inner wall of the uterus(11).
8. Irritable bowel syndrome
Women with endometriosis in the bowel region frequently have abdominal and bowel symptoms, specially during the menstrual cycle. Bowel symptoms may be attributed to irritable bowel symptoms or caused by intestinal involvement from endometriosis.(9).
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References
(1) Dysmenorrhea, Absenteeism from School, and Symptoms Suspicious forEndometriosis in Adolescents.by Zannoni L1, Giorgi M2, Spagnolo E2, Montanari G2, Villa G2, Seracchioli R2(PubMed).
(2) Prevalence and impact of dysmenorrhea on Hispanic female adolescents.by Banikarim C1, Chacko MR, Kelder SH(PubMed)
(3) WITHDRAWN: Laparoscopic surgery for subfertility associated withendometriosis.by Jacobson TZ1, Duffy JM, Barlow DH, Farquhar C, Koninckx PR, Olive D.(PubMed)
(4) Endometriosis and pregnancy outcome: are pregnancies complicated byendometriosis a high-risk group? by Mekaru K1, Masamoto H2, Sugiyama H2, Asato K2, Heshiki C2, Kinjyo T2, Aoki Y2.(PubMed)
(5) Do women with endometriosis have to worry about sex? by Di Donato N1, Montanari G2, Benfenati A2, Monti G2, Bertoldo V2, Mauloni M3, Seracchioli R2.(PubMed)
(6) Women with deep infiltrating endometriosis: sexual satisfaction, desire, orgasm, and pelvic problem interference with sex by Montanari G1, Di Donato N, Benfenati A, Giovanardi G, Zannoni L, Vicenzi C, Solfrini S, Mignemi G, Villa G,Mabrouk M, Schioppa C, Venturoli S, Seracchioli R.(PubMed)
(7)Menstrual patterns, pain symptoms, body mass index and smoking habits in women with endometriosis by Montanino G1, Montanino Oliva M, Gulemà L, Boninfante M, Cosmi EV.(PubMed)
(8) Endometriosis and pelvic pain: epidemiological evidence of the relationship and implications by Fauconnier A1, Chapron C.(PubMed)
(9) Irritable bowel syndrome and chronic constipation in patients withendometriosis. by Meurs-Szojda MM1, Mijatovic V, Felt-Bersma RJ, Hompes PG.(PubMed)
(10) Potential strategies to avoid progestogen induced premenstrual disorders by Baker LJ1, O'Brien PM.(PubMed)
(11) Polypoid endometriosis of the cervix: a case report and review of the literature by Jaiman S1, Gundabattula SR, Pochiraju M, Sangireddy JR.(PubMed)
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