Menstrual Disorders: Menorrhagia - Hormones Treatments of Secondary Menorrhagia in Conventional Medicine

Menorrhagia is defined as a condition of excessive bleeding in the menstruation phase of the menstrual cycle in the reproductive age of a woman leading to heavy blood loss that can interfere with the woman normal activities, as a result of disruption of normal hormonal regulation of periods or disorders of certain reproductive organs.


Hormone Treatments of Secondary Menorrhagia in Conventional Medicine
1. Contraceptive pill
a. Low-dose combination birth control pills which contains low-dose synthetic forms of the hormones estrogen and progesterone may be use to treat amenorrhea by controlling the menstrual cycle or bring the period back.
b. Risks and side effects
b.1. Growth of fibroids
Growth of fibroid is caused high level of estrogen and progesterone. The intake of the pill increase the level of both hormones resulting in increase the risk of growth of fibroid.
b.2. Recurrent of menstrual symptoms
Some women stop taking the pill may see all the menstrual symptoms coming back.
b3. Blood clots
Estrogen in the pill may cause blood clots in the small vessels in the leg and the lung.
b.4. Stroke and heart diseases
Study shows that women who have higher natural estrogen levels may have a higher risk of stroke and heart diseases.
b.5. Depression and mood swing
At the beginning, it may cause abnormal fluctuations in estrogen and progesterone elevate both physical and psychological stress, eventually resulting in both depression and mood swing
b.6. Bleeding and spotting
Bleeding and spotting is normal for the first six months for women who begin with any oral contraceptive combination pill treatment.
b.7. Lost interest in sex
Some women may experience lower sexual desire
b.8. Nutritional deficiency
Oral contraceptive pill causes vitamin and mineral imbalances or deficiencies.
b.9. Etc.

2. Norethisterone (Progesterone only pill)
Norethisterone a progestogen and has been used used treat premenstrual syndrome, painful periods, abnormal heavy bleeding, irregular periods. In a study of A comparative study of danazol and norethisterone in dysfunctional uterine bleeding presenting as menorrhagia M. Bonduelle, J.J. Walker and A.A. Caldert, researcher found that Since this study was undertaken, a report of
objective measurement of blood loss in small groups of patients9 casts further doubt on the
efficacy ofnorethisterone, although it confirms that of danazol. Since norethisterone is very widely used, a detailed assessment of its efficacy and safety in comparison to danazol is overdue. Should such a study confirm the findings discussed here then danazol could usefully be employed as first line therapy in the management of dysfunctional uterine bleeding presenting as menorrhagia.

3. Danazol
Danazol is synthetic steroid ethisterone, a modified testosterone that is used to inhibit ovarian steroidogenesis resulting in decreased secretion of estradiol and may increase androgens. although it is a standard medicine in treating menorrhagia
According the study of Efficacy of vaginal danazol treatment in women with menorrhagia during fertile age by Luisi S, Razzi S, Lazzeri L, Bocchi C, Severi FM, Petraglia F., researchers concluded that vaginal danazol resulted in effective medical treatment in young women with menorrhagia, and, because of a lack of significant adverse effects, it may be proposed as an alternative treatment.

4. Contraceptive coil (Mirena)
a. It is a soft, flexible T-shaped (birth control) device placed inside the uterus by your doctor within 7 days after the start of your period with medication Mirena continuous release over a period of 5 years to prevent pregnancy and reduce symptoms of menorrhagia. According to the study of SAFETY AND EFFICACY OF MIRENA IN MENORRHAGIA : 10 YEARS RESULTS OF VUOKKO-STUDY by R. Hurskainen, researcher suggested The preliminary 10-year results of Vuokko study show that LNG-IUS is a good alternative option to hysterectomy in the treatment of menorrhagia. Although half of the women assigned to the LNG-IUS group eventually underwent hysterectomy, the costs remain significantly lower than in hysterectomy group. The transition from menorrhagia to menopause seems to be well tolerated and associated with a favourable bleeding pattern.
b. Risks and side effects
b.1.Spotting between periods
b.2. Complete absence of menstrual flow
b.3. Decreased bleeding during periods
b.4. Prolonged bleeding during periods
b.5. Breast pain and tenderness
b.6. Etc.

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