Posted by Chantel M. Contributed by US National Library of Medicine National Institutes of Health
In the study of "Age-stratified serum levels of isoflavones and proportion of equol producers in Japanese and Korean healthy men" by Fujimoto K, Tanaka M, Hirao Y, Nagata Y, Mori M, Miyanaga N, Akaza H, Kim WJ., posted in US National Library of Medicine National Institutes of Health, researchers found that In the Japanese study, the proportion of equol producers in the teenager
group was 10%, being significantly the lowest among the age-stratified
groups. The proportions of equol producers in the age-stratified groups
from 10 to 49 years were also significantly lower than those in the
fifties. The equol non-producers consumed significantly less amounts of
isoflavones than the equol producers. In the Korean study, the
proportions of equol producers were 45% in the teenager and 40% in the
twenties and thirties, being significantly lower than in the forties
(80%) and fifties (65%). The decreased intake
of isoflavones, low serum level of equol and low incidence of equol
production in the young generation may become potential risk factors for
prostate cancer not only in Japan but also in Korea in the near future.
Elucidating the mechanism of equol production may be promising in
developing strategies for chemoprevention against prostate cancer.
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