Posted by Chantel Martiromo. research contributed by PubMed
In the quasi-randomized trial, 146 subjects with PCOS divided into two
groups; the experimental group who received Genistein (Bergamon, Italy)
18 mg twice a day orally and the control group that received similar
capsules with cellulose for 3 months. Hormonal features and lipid
profiles were measured before and after 3 months of supplement therapy., posted in PubMed, indicated there were no statistically significant differences in high density
lipoprotein cholesterol (HDL) and follicle stimulating hormone (FSH)
serum levels in Genistein and placebo group before and after treatment;
however serum levels of luteinizing hormone (LH), triglyceride (TG), low
density lipoprotein cholesterol (LDL), dehydroepiandrostrone sulfate
(DHEAS) and testosterone were significantly decreased after 3 months
therapy in Genistein group and suggested that Genistein consumption may prevent cardiovascular and metabolic disorders in PCOS patients by improving their reproductive hormonal and lipid profiles.
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