Posted by Chantel Martiromo, Article By Kyle J. Norton
Polycystic Ovarian Syndrome is defined as
endocrinologic diseases caused by undeveloped follicles clumping on the
ovaries that interferes with the function of the normal ovaries as
resulting of enlarged ovaries, leading to hormone imbalance( excessive
androgen), resulting in male pattern hair development, acne,irregular
period or absence of period, weight gain and effecting fertility. It
effects over 5% of women population or 1 in 20 women.
II. Symptoms of PCOs
1. Irregular or absent menstrual periods
2. Male pattern hair growth
3. Acne and oily skin
4. Over weight
5. Obstructive sleep apnea
Closure of the upper airway, causing stop breathing while sleeping
6. Difficult to conceive
you have above symptoms, you may have PCOs. It is for your benefit to
visit your doctor or gynaecologist immediately, because it may effect
your chance of fertility. It is easy to identify through your medical
history, physical exam and a blood test. In fact, the most effective
long term treatment for PCOs can be done naturally at comfort at your
The blood test includes testing of
SHGB, LH and FSH ratio, TSH, IGTT level ( fasting insulin) and several
other androgens are used to evaluate adrenal function. If there are
abnormal secretion of certain hormones, you may be in a high risk of
having PCOs. You may also require to have an ultra sound to look at
IV. Causes of PCOs
The causes of polycystic ovarian syndrome is still unknown, but there are some suggestions
1. Genetic predisposition
genetic predisposition is defined as a genetic problem of some women
who were born predisposed to certain health problem. In this case, it is
polycystic ovarian syndrome.
2. Insulin resistance
resistance is defined as above normal level of insulin in the blood of a
person. It may be caused other health problem such as diabetes,
abnormal function of pancreas or caused by low numbers of the insulin
sensitivity of cells, which impairs the process of glucose in energy
conversion and high blood glucose levels in the body, leading to hormone
imbalance resulting in increasing the risks of cystic follicles or
ovarian cysts development.
Obesity is defined as a person whose BMI index
is over 24. As we known, obesity women is always associated to insulin
resistance, leading to the same problem as mentioning above.
is a medical condition characterized by excessive production and/or
secretion of androgens leading to male pattern hair growth.
develops when follicles in androgen sensitive areas start to form
thick, pigmented hair as opposed to thin, short, non-pigmented hair
normally seen in those areas in women.
b) Cushing syndrome
syndrome is a chronic illness caused by over production of cortisol
hormone leading to lower sperm production in male and abnormal
ovulation in women.
c) Disorders of cortisol metabolism,
is usually referred to as the stress hormone, as it is secreted in
large volume for our body to response to stress and anxiety. Disorders
of cortisol metabolism is defined as a condition of which cortisol
hormone has losen its function in restoring homeostasis after stress
and inhibited insulin, causing blood sugar to rise.
is produced by the anterior pituitary gland primarily which plays
important breast development during pregnancy and milk production after
birth. Hyperprolactinaemia effects the normal function of the
hypothalamus and pituitary gland, leading to ovulatory infertility, a
decreasing in menstruation and sometimes lost of menstruation and lost
of sexual desire.
Acromegaly is defined as over
production of growth hormones caused by a benign tumor or of the
pituitary gland and in rare case, it may be caused by tumors of the
pancreas, lungs, and adrenal glands, leading to excess GnRH, resulting
in male pattern hair growth.
5. Environmental chemicals
chemicals such as xanoestrogen can causes over production of certain
hormone and reduction of others, leading to abnormal function of the
reproductive organs including the development of follicles and
increasing the risk of PCOs.
6. Food adulterantion
adulterantion is defined as admixture or substitution of inferior
substances or by the removal of some valuable ingredient in foods,
leading to hormone imbalance and distorting the natural process of women
7. Chronic inflammation
inflammation, known as chronic inflammation, leads to a progressive
shift in the type of cells which are present at the site of inflammation
and is characterized by simultaneous destruction and healing of the
tissue from the inflammatory process.
V. Types of Conventional treatments
a) The effectiveness of metformin
is an oral anti-diabetic drug used to treat type II diabetes. It is
also used widely in treating PCOs by suppressing the production of
endogenous glucose by the liver as it helps to make insulin working more
effective without changing the level of insulin in the body, thereby
helping to regulate the production of certain hormones resulting in
ovulation and egg production.
b) Side effects: i) Gastrointestinal upset including diarrhea, cramps, nausea and vomiting.
ii) Buildup of lactic acid in the body.
iii) Abdominal pain or cramps.
2. Clomiphene (Clomid)
a) The effectiveness of chomiphere
is considered as a fertility medication. The effectiveness of
clomiphere is that it helps to induce ovulation in women who are not
ovulating at all and to increase the production of egg for women with
letual phrase defect by stimulate the function of pituitary gland in
series of hormone production, including LH, FSH and egg follicles.
b) Side effects
i) abdominal pain and cramps.
ii) Breast tenderness.
iii) Ovaries swelling,
v) Gastrointestinal disorder including nausea, and vomiting.
a) The effectiveness of HCG
Human Chorionic Gonadotropin
(HcG) is defined as a hormone secreted by specialized cells called
trophoblasts and later by the placenta. Since it is similar in structure
to LH, it helps to induce ovulation by stimulating the release of
mature egg, approximate 36 hour after taking it. HCG not only pinpoint
the best time for sexual intercourse with success conception or
assisting intrauterine insemination in egg retrieval.
b) Side effects
Although side effects of HCG is not common, but some women may experience
iii) Restlessness, slight
iv) Water retention
v) Breast tenderness
4. Gonadotropin (HMG)
a) The effectiveness of HMG
natural FSH and LH, is a purified form of urine of post menopausal
women. By stimulating production of LH and FSH to right levels, it
helps to induce ovulation and develop mature follicles. if you are
found to have low natural gonadotropin or estrogen levels or you need
to have multiple egg follicles for artificial insemination. The
medication may be also used if chomiphere therapy and other medication
have been failed to induce ovulation.
b) Risks and side effects
i) Risk of miscarriage ( Quality of egg does not address here)
ii) Ovarian enlargement ( Caused by over stimulation)
iii) Ovarian hyper stimulation syndrome (OHSS)
iv) Multiple pregnancy
v) Headache and abdominal pain and cramps.
vi) Breast tenderness
a) The effectiveness of dexamethasone
is a synthetic member of the glucocorticoid class of steroid hormones
and a prescribed medication for fertility but does not use frequently
as the other medication. It helps to induce ovulation by suppressing
the androgen levels, resulting in increasing the chance of fertility.
b) Side effects
i) Stomach upset
ii) Glucose intolerance
iii) Moodswing and irritability
v) Water rentention
6. Artificial Insemination (In Vitro Fertilization (IVF))
a) The effectiveness of IVF
Vitro Fertilization (IVF) may also be offered, if other medication
treatment have failed to induce pregnancy for women with PCOS by using
HCG or other medication to induce ovulation and egg retrieval.
b) Risks and side effects
a) Ovarian hyperstimulation
b) Pelvic pain and cramps,
c) Shortness of breath,
d) Blood chemistry abnormalities
is not commonly performed. If necessary, PCOs can be treated by either
a laparoscopic surgery also is known as ovarian drilling or wedge
resection. Both methods have not proven to be effective for women with
PCOs. It is your benefit to forgo this type of expensive treatment in
favor of other such as IVF.
Remember the most effective long term treatment for PCOs can be done naturally at comfort at your own home.
have spent most of our times in discussing "Fertility and PCOs in
Conventional medication Perspective", we will come back with another
article " Fertility and PCOs with General Perspective". At the meantime,
Always keep yourself positive and work together with your doctor, you may get pregnant sooner than you think
The Natural Pcos Diet
At Last! A Naturopath’s Easy Step-by-Step
Guide to Overcoming PCOS Is Now Available!
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