Women Health: The Smoothie of Cooked Sweet Potato, Orange and Sunflower seed for reduced risk and treatment of Endometriosis

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


The smoothie for reduced risk and treatment of endometriosis
Yield: 2 serving (about 8 ounce each)
1/2 cups sweet potato
3/4 cup orange
1/4 cup sunflower seed
1 cup of rice milk

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding the natural ingredients for treatment of endometriosis is considered as a dream of many scientist to replace the long term usage adverse effect of conventional medicine.
Unfortunately, many compounds found effective in initial studying failed to confirm the similar potentials in large sample size and multi center.

Endometriosis is a condition of endometrial tissues grown outside the Due to its reaction to hormone signals of the monthly menstrual cycle, building up tissues, breaking it and eliminating it through menstrual period, endometriosis also cause severe pelvic pain.

Recent studies suggested that scientist in some research centers have found the naturally potential ingredients of antioxidant supplementation in ameliorated endometriosis-associated symptoms, including vitamin C(1), E(1) and A(2).

Sweet potato is a large, starchy, sweet tasting tuberous roots vegetable, genus Ipomoea, belongings to the family Convolvulaceae. The root vegetable contains a highest amount of vitamin A in comparison to other foods in the same content,

According to the joint study lead by the University of Maryland School of Pharmacy, the impairment of retinoic acid biosynthesis involved in the transport of retinol (vitamin A alcohol) from the liver storage site to peripheral tissue.is associated to the development of human and murine endometriosis(3).

Dr. Sokalska A and research team at the University of California said, " the expression of the key protein regulating the uptake of retinol (STRA6) and the expression of apoptosis-promoting CRABP2,....may contribute to cooperative apoptosis-inducing effects of simvastatin and RA and support the examination of these compounds in the treatment of endometriosis" in the investigation of the effects of simvastatin on retinoic acid system against endometriosis(4).

Vitamin C, alangeso known as L-ascorbate, a water soluble vitamin with a chemical structure formula of C6H6O6 found abundantly in orange is  best known for it's antioxidant property in strengthening the immune system against any inflammatory diseases, including endometriosis(1).
In experimental endometriotic cysts study, vitamin C in dose-dependent ameliorated the volumes and weights of the endometriotic cysts(5).

According to the Instituto Nacional de Perinatología, regular intake of vitamin C and E, lowered oxidative stress marker levels in attenuated the symptoms of endometriosis(6).

In fact, intake of vitamin C and  vitamin E expressed a a positive association between the pathology development and the lipoperoxidation status in women with endometriosis(7).

Vitamin E, best known for its powerful antioxidant property a fat soluble vitamin found abundantly
in sunflower seed. According to the Maternal and Child Health Hospital of Guangdong Province, intake of vitamin E in patient with endonetriosis decreased oxidative stress, as well as improved mature oocyte rates and fertilization rates(8).

In fact, regular intake of "vitamin E from food sources are found inversely related to endometriosis risk" Dr. Darling AM and colleagues at the joint study lead by the Harvard School of Public Health said.
The discovery of combined ingredients of Sweet Potato, Orange and Sunflower Seed may act as a cornerstone for induction of further investigation of the effectiveness of natural smoothie in reduced risk and treatment of endometriosis.

People who are at increased risk of endometriosis due to family history, ... may drink one or 2 servings a day, people with endometriosis should drink as much as they can depending to the digestive alternation.
Life style and dietary pattern change are recommended.

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References, 

(1) Antioxidant supplementation reduces endometriosis-related pelvic pain in humans by Santanam N1, Kavtaradze N, Murphy A, Dominguez C, Parthasarathy S.(PubMed)

(2) Women with endometriosis improved their peripheral antioxidant markers after the application of a high antioxidant diet by Mier-Cabrera J1, Aburto-Soto T, Burrola-Méndez S, Jiménez-Zamudio L, Tolentino MC, Casanueva E, Hernández-Guerrero C.(PubMed)

(3) Retinoic acid biosynthesis is impaired in human and murine endometriosis by Pierzchalski K1, Taylor RN2, Nezhat C3, Jones JW1, Napoli JL4, Yang G5, Kane MA6, Sidell N7(PubMed)

(4) Effects of simvastatin on retinoic acid system in primary human endometrial stromal cells and in a chimeric model of human endometriosis by Sokalska A1, Anderson M, Villanueva J, Ortega I, Bruner-Tran KL, Osteen KG, Duleba AJ.(PubMed)

(5) Effect of vitamin C on the growth of experimentally induced endometriotic cysts by Durak Y1, Kokcu A, Kefeli M, Bildircin D, Çelik H, Alper T.(PubMed)
(6) Effect of vitamins C and E supplementation on peripheral oxidative stress markers and pregnancy rate in women with endometriosis. by Mier-Cabrera J1, Genera-García M, De la Jara-Díaz J, Perichart-Perera O, Vadillo-Ortega F, Hernández-Guerrero C.(PubMed)
(7) [Endometriosis and deficient intake of antioxidants molecules related to peripheral and peritoneal oxidative stress].[Article in Spanish]by Hernández Guerrero CA1, Bujalil Montenegro L, de la Jara Díaz J, Mier Cabrera J, Bouchán Valencia P.(PubMed)
(8) Oxidative stress impairs oocyte quality and melatonin protects oocytes from free radical damage and improves fertilization rate. by Tamura H1, Takasaki A, Miwa I, Taniguchi K, Maekawa R, Asada H, Taketani T, Matsuoka A, Yamagata Y, Shimamura K, Morioka H,Ishikawa H, Reiter RJ, Sugino N.(PubMed)
(9) A prospective cohort study of Vitamins B, C, E, and multivitamin intake and endometriosis. by Darling AM1, Chavarro JE2, Malspeis S3, Harris HR4, Missmer SA5.(PubMed)