Herbal Burdock, the Best Anti Diabetes and Diabetic Complications Functional Remedy, Scientists Find

Scientists may have found a herbal medicine for the prevention and treatment of diabetes with no side effects, according to studies.

Diabetes is a medical and chronic condition caused by insufficient insulin entering the bloodstream to regulate the glucose.

The disease is either caused by cells in pancreas died off or receptor sites clogged up by fat and cholesterol.

Some researchers suggested that high blood cholesterol is one major risk factor not only contributed to the risk of obesity but also facilitates the onset of diabetes.

How to calculate your blood cholesterol, If the ratio your blood cholesterol is higher than 4, you have high blood cholesterol.

The normal ratio of blood cholesterol is 4 (low-density lipoprotein or bad cholesterol)/ 1 ( high-density lipoprotein or good cholesterol). Any number which is higher than 4 is considered high blood cholesterol.

How high blood cholesterol associated with diabetes
* Most patients with diabetes also have a syndrome oh high blood cholesterol.

* According to Dr. Michael Greger M.D long-term intake of a high-fat diet is associated with diabetes. According to the study of young, healthy people and split them up into two groups, high fat intake within 2 days demonstrated, a significant rise of glucose intolerance. During the course of study, the high-fat diet group ended up with twice the blood sugar compared to the carbohydrate-rich diet group.

* Also the spike of blood sugar in the high-fat diet group may also increase the onset of insulin resistance due to insulin no longer performs its function in activating the function of the insulin receptors site which now clogged up by cholesterol to stimulating the enzymes associated with glucose transport.


In other words, the pancreas beta cells will continue to produce insulin but can not lower the blood glucose due to the disruption of glucose metabolism, leading to insulin resistance, the major cause of diabetes.


Burdock is a plant in the group of biennial thistles, genus Arctium, belonging to the family Asteraceae, native to the Euro. The herbal medicine has been using thousands of year in China and other traditional herbal medicine as a diuretic, diaphoretic, and a blood purifying agent and to treat wounds and infections stomach ulcers and other digestive problems.

It contains carbonated water, sugar,, manloid colorings, phosphoric acid, citric acid and a good amount of dietary fiber, calcium, potassium, and amino acids and chemicals compounds of guaianolide, arctinone, arctinal, methyl arctate，11-tridecadien-3，5，7，9-tetraynde-hydrocostus lactone，dehydrodihydrocostus lactone, 3-octenoic acid, 3-hexenoic acid etc.

With an aim to find a natural medicine for the treatment of diabetes and reduced the diabetic retinopathy is one of the most common and severe complications of diabetes mellitus, researchers at the Third Military Medical University examined Arctiin, a bioactive compound isolated from the dry seeds of Arctium lappa L.(Burdock), antidiabetic activity.

Male Sprague-Dawley rats induced diabetes are randomly divided into five groups (n = 20 per group) and treated with intragastric doses of 30, 90, or 270 mg/kg/d wt of arctiin, 100 mg/kg/d wt of calcium dobesilate, or 0.5 % CMC-Na and 20 nondiabetic sham-treated rats were treated with 0.5 % CMC-Na.

In the beginning, there was no significantly different occurrence of diabetic retinopathy among the groups.

However, at the week 16, the glycosylated hemoglobin (HBA1c) level was significantly decreased in all of the arctiin-treated groups when compared with the control group, and the serum glucose level was also decreased in the rats treated with the highest dose of arctiin


The normal levels of HbA1c of 6.5% and HbA1c are used as an objective measure of glycaemic control.


The highest dose of the arctiin group showed a decrease in the serum glucose level which was elevated by the induction of diabetes.


Arctiin treatment group displayed a reduced inflammatory in the expression of retinal edema, detachment of the retina, and levels of pro-inflammatory cytokines observed by the histological and immunochemical examinations.


Furthermore, arctiin also increased the viability of retinal microvascular endothelial cells which reduced in diabetic rats, in vitro.

Dr. Lu LC, the lead scientist wrote, "these findings demonstrate that arctiin decreases the severity of diabetic complications, demonstrating the importance of this compound as an inhibitor of diabetic retinopathy".


Additionally, in the review of anti-diabetes effects of the active compounds present in the different botanical parts of burdock, researchers examined the active ingredients in the roots and seed.


The results of chemical analysis suggested that the compounds isolated from root showed a strong effect in the inhibition of diabetes through its antioxidant activity.

In the seeds, some active compounds possess anti-inflammatory effects similar to that of arctiin treatment rats group.

These results suggested that herbal burdock exerted a strong anti-diabetes and diabetic complication through its glycaemic control and antioxidant and anti-inflammatory properties.


Taken altogether, herbal Burdock processed high numbers of the bioactive compound may be considered a functional herb for the prevention and combined with the primary medicine for the treatment of diabetes and diabetic complication.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Effects of arctiin on streptozotocin-induced diabetic retinopathy in Sprague-Dawley rats by Lu LC, Zhou W, Li ZH, Yu CP, Li CW, Luo MH, Xie H.(PubMed)
(2) A review of the pharmacological effects of Arctium lappa (burdock) by Chan YS1, Cheng LN, Wu JH, Chan E, Kwan YW, Lee SM, Leung GP, Yu PH, Chan SW. (PubMed)
(3) Fat is the Cause of Type 2 Diabetes by Written By Michael Greger M.D. FACLM on November 17th, 2016. (Nutrition Facts)