The Phytochemicals That Suppress Over Growth of Candida, Scientists Say

Candida albicans are members of a large group of microorganism whose cells contain complex structures enclosed within the membranes, including yeast(2)(3), fungi(4)(5)(6), and mold(6) that live among the gut flora in the human mouth and gastrointestinal tract.

Non-albicans Candida (NAC) species cause 35-65% of all candidaemias in the general patient population(1).

Phytochemicals are various biologically active compounds found in plants.


The major function of these chemical compound is to protect the host plant against oxidation

Today, the name list of phytochemicals found in plants are only represented a tiny fraction of entire phytochemicals family.

According to general belief, human will never find a complete list of phytochemicals in plants which contains millions of known and unknown species.

In human, intake of phytochemical regularly from food sources is found to exhibit certain health benefits, including

* To act as an antioxidant against free radical overexpression in the initiated change of cellular DNA - the early onset of developing certain types of cancer(a)

* To act as hormones modulator against the imbalance of hormone in the host(b).

* To act as enzymes stimulator again the st imbalance of ratio of host antioxidant and ROS levels(c).

High levels of free radical facilitated oxidative stress are associated with the risk of chronic physical and mental health.

Imbalance of ratio of ROS species and antioxidant enzymes in the host tissue have played an essential role in the initiated expression of healthy cell cytotoxicity that can alternate DNA transcription in precipitated the development of chronic ailments such as overgrowth of candida.

* To act as anti-infection agent(d) against microorganisms which cause inflammation due to acute and chronic infection.

In many cases, biofilm(microorganisms with cells stick to each other on a surface) formation(7) gene mutations(8) and over expression of genes(9)(10) are often associated with increased candida resistance toward antifungal drugs.

The Anti Over Growth of Candida Phytochemicals
1. L-glutamine
L-glutamine is one of the 20 amino acids encoded by the standard genetic code and used to treat certain gastrointestinal disorders(342)(343) by serving as a source of fuel for the cells that line the gastrointestinal tract.

According to Ankara University, L-glutamine inhibited the over growth of candida through its antimutagenic and antimicrobial activities(344).

2. N-acetyl-glucosamine
N-acetyl-glucosamine is a monosaccharide derivative of glucose that supports the digestive track function and maintains healthy intestinal lining by stimulating cell growth in the intestinal tract(345).

According to National Institute of Plant Genome Research, GIG2 (GlcNAc-induced gene 2). involved in the metabolism of N-acetylneuraminate (sialic acid), effectively decreased fungal burden in the mouse model(346).

3. Rice-bran oil Extracted
from the germ and inner husk of rice, containing a compound gamma-oryzanol(347) showed to reduce the risk of gastric ulcers caused by stress while at the same time maintaining gastrointestinal motility(348).

According to Manipal Academy of Higher Education (Deemed University, rice bran oil immobilized lipase from Candida, a potential pathway for fungal overgrowth(349).

4. Pancreatic enzymes supplements
Pancreatic enzymes found as supplements and in certain foods allow more bacteria to grow in the intestine by enabling the food to be digested a lot easier(350). Insufficient pancreatic enzymes can quickly encourage Candida overgrowth in the digestive tracts(351).

5. Butyric acid
Butyric acid, a fatty acid occurring in the form of esters in animal fats and plant oils, was effective in inhibited pathogenic organisms(352) through improved digestion and promoted intestinal health(353) by producing bacteria to feed on lactic acid, then multiplying and revving up their production(354).

Butyric acid also consists anti-inflammatory property(355) and strengthens the intestinal mucosal barrier. (356).

5. Fructo-oligosaccharides(FOS)
Fructo-oligosaccharides(FOS) is a class of oligosaccharides used as an artificial or alternative sweetener(357), extracted from fruits and vegetables such as bananas, onions, chicory root, garlic, asparagus, barley, wheat, tomatoes, and leeks(358). It is inulin-type prebiotics(359), stimulated the growth of friendly bacteria in the intestine track to counter react to other bad bacteria(360)(362) such as candida. Oligosaccharides also induce gas formation, through increasing fecal biomass and water content of the stools, for improvement of bowel habits(361),



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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

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