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Tuesday, November 15, 2011

Soy and Macrophage Phagocytosis and Lymphocyte

Posted by Chantel M. Contributed by US National Library of Medicine National Institutes of Health


According to the study of "Soy lecithin supplementation alters macrophage phagocytosis and lymphocyte response to concanavalin A: a study in alloxan-induced diabetic rats" by Miranda DT, Batista VG, Grando FC, Paula FM, Felício CA, Rubbo GF, Fernandes LC, Curi R, Nishiyama A., posted in US National Library of Medicine National Institutes of Health, researchers found that Soy lecithin supplementation significantly increased both macrophage phagocytic capacity (+29%) in non-diabetic rats and the lymphocyte number in diabetic rats (+92%). It is unlikely that plasma lipid levels indirectly affect immune cells, since plasma cholesterol, TAG, or phospholipid content was not modified by lecithin supplementation. In conclusion, lymphocyte and macrophage function were altered by lecithin supplementation, indicating an immunomodulatory effect of phosphatidylcholine.

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