Posted by Chantel M. Contributed by US National
Library of Medicine National Institutes of Health
In a 1-year double-blind, randomized trial to compare the effects of
isoflavone (75 mg of isoflavone conjugates/day) with those of placebo on
bone mineral density, fat mass, and serum isoflavone concentrations in
early postmenopausal Japanese women who were classified based on their
equol-producer phenotype by Wu J, Oka J, Ezaki J, Ohtomo T, Ueno T, Uchiyama S, Toda T, Uehara M, Ishimi Y., posted in PubMed, showed that the preventive effects of isoflavones on bone loss and fat accumulation
in early postmenopausal women depend on an individual's equol-producing
capacity.
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