Posted by Chantel M. research contributed US National Library of Medicine
National Institutes of Health
In the study to explore
the effect of the phytoestrogen daidzein on the growth and development
of the testis and epididymis in male SD rats, posted in PubMed, researchers at the Nanjing Normal University, found that the early adult rats showed no significant differences in body weight and
testicular and epididymal indexes between the claiclzein groups and the
control (P > 0.05), nor did the pubertal rats in epididymal index (P
> 0.05). The testicular index differed significantly between the
high-dose group (3.21 +/- 0.07) and the normal control (3.71 +/- 0.45)
(P < 0.05). The body weight reduced markedly in the high-dose group
(P < 0.05), but with no significant differences between the normal
control and the other two dose groups (P > 0.05). No obvious changes
were observed in epididymal morphology in all the daidzein groups of the
early adult and pubertal rats, but high-dose daidzein resulted in
smaller testes and impaired spermatogenesis.
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