Posted by Chantel M. research contributed US National Library of Medicine
National Institutes of Health
In
the study to investigate the preventive effect of the phytoestrogen
daidzein on prostatic hyperplasia induced by testosterone in rats posted
in PubMed,
suggested that medium- and high-dose daidzein induced a more obvious
alleviation of
prostate hyperplasia, characterized by thinner epithelia, decreased
secretions in the glandular cavity and reduced interstitial tissues. The
expression of ERalpha showed no significant difference between the
model group and the other groups, while that of ERbeta was markedly
decreased in the daidzein-treated groups as compared with the normal
control or the model group. The phytoestrogen daidzein has some
preventive effect on prostatic hyperplasia induced by testosterone in
rats.
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