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Sunday, August 11, 2013

A new perspective on the quercetin paradox in male reproductive dysfunction

Posted by Chantel Martiromo. research contributed by PubMed

In the study of addressing this paradoxical behavior of quercetin by taking into account the in vitro and in vivo studies conducted till date regarding its role in the maintenance of male reproductive potential, posted in PubMed, showed that the conflicting biological effects of quercetin might relate to its dose and the redox state of the cell. Thus, the cellular toxicity of quercetin metabolites might overshadow the beneficial effects of its supplementation in subjects having reproductive dysfunction coupled with elevated oxidative stress leading to the paradoxical behavior of the flavonoid. Copyright © 2012 John Wiley & Sons, Ltd.

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