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Wednesday, October 24, 2018

The Natural Remedies That Inhibit Over Growth of Candida, Scientists Say

Candida albicans are members of a large group of microorganism whose cells contain complex structures enclosed within the membranes, including yeast(2)(3), fungi(4)(5)(6), and mold(6) that live among the gut flora in the human mouth and gastrointestinal tract.

Non-albicans Candida (NAC) species cause 35-65% of all candidaemias in the general patient population(1).

According to joint study, in many cases, biofilm(microorganisms with cells stick to each other on a surface) formation(7) gene mutations(8) and overexpression of genes(9)(10) are often associated with increased candida resistance toward antifungal drugs.

Herbal medicine or phytotherapy is a traditional practice used botany and plants for treatment of a variety of diseases.

Today, due to serious side effects caused by intake of conventional single ingredient medication, some scientists once again have looked into herbal whole food plant with an aim to find the replacements with similar effect without inducing the adverse effect.

These journeys have encountered many problems, as the discovery of such plants will provide no commercial benefit and patent right to producers. Particularly, if such plants are found, they will exert a major blow in cutting into sizable benefits of big pharmaceutical companies

Truly, between 25 to 50% of current pharmaceuticals derived from plants, none are used as antimicrobials(b).


Some researchers suggested that duplicated herbal successes of Western drugs with the synthetic version for the patent right without using the whole herb ingredients for commercial profits may eventually contribute to overexpression of serious adverse effects(b).

Imbalance of ratio of ROS species and antioxidant enzymes in the host tissue have played an essential role in the initiated expression of healthy cell cytotoxicity that can alternate DNA transcription in facilitating the development of chronic ailments such as overgrowth of candida.

In free radical over expression cause of over growth candida, certain natural alternatives exerted a strong antioxidant effect that target Candida.

According to Dr. Seneviratne CJ at the University of Hong Kong, in the study of "Potent anti-traditional Chinese herbal plant contains significant and potent antifungal activities, such as Rhizoma Coptidis and Cortex phellodendri Chinesis on three different non-albicans Candida species, C. glabrata, C. krusei and C. tropicalis(a).


The Anti Over Growth of Candida Natural Alternatives
1. Manuka Honey
Manuka honey has been known to benefit humans in healing wounds and injuries(309) without inducing damage to cells. The product also contains hydrogen peroxide claimed to have antimicrobial property(310), including Candida albicans(311).


2. Undecylenic acid

Undecylenic acid is the common name of the 10-undecenoic acid, an organic unsaturated fatty acid derived from castor oil, It is a natural antimicrobial property(312)against fungal skin infections(313)(314) and Candida albicans(315).


3. Caprylic acid
Caprylic acid is the common name for the eight-carbon saturated fatty acid found naturally in coconuts and breast milk, used in treatments for a variety of conditions, including Candida(316)(317).


4. Echinacea angustifolia

Echinacea angustifolia is a herbaceous plant species Echinacea angustifolia, belongings to the family Asteraceae native to Northern America. Echinacea angustifolia besides enhances the immune system function(318)(319) against the invasion of bacteria and viral through its antioxidant effects, it also used to treat bacterial infections(320) and candida(318) in herb medicine.


5. Horopeit
Horopeit is a genus Pseudowintera, part of family Winteraceae. The herb contains a compound polygodial, a chemical compound used to suppress the growth of candida(321)(322) by damaging the permeable cell membrane of yeast(322).


6. Oregano
Oregano is a genus of the mint family Lamiaceae, native to southwestern Eurasia and the Mediterranean region. The herb not only promotes digestive health(323), clear skin and healthy immune system(324) but also dehydrates candida(325) by reacting with the water in the bloodstream, through its phytochemicals Carvacrol and Thymol(326).


7. Aloe vera
Aloe vera is a genus Aloe belongings to the family Asphodelaceae, originated in Sudan. Beside containing significant amounts of amino acids, enzymes, vitamins, minerals and antioxidants which help to enhance the immune function(327) in fighting against virus and bacterial infection and inflammation(328), it also maintains a proper PH levels that inhibit the growth of candida(329) and repairs and seals the intestinal wall, which stops Candida from actually penetrating through and into your bloodstream(330).


8. Tea tree oil
Tea tree oil is a pale yellow color to nearly clear essential oil extracted from the leaves of the Narrow-leaved Tea-tree, native to the northeast coast of New South Wales, Australia. In Fluconazole-resistant candida Albicans strains, dose-depend manner, tea tree oil strongly exhibited fluconazole activity against fluconazole-resistant C. albicans strains, through its antifungal activity(331).


Terpinen-4-ol, the main bioactive component found in teat tree oil, also showed to accelerate clearance of all Candida strains from the vagina, including the azole-resistant forms in rat vaginal infection model(332)


9. Tannate plant extracts
Tannate is the salt or ester of tannic acid. Tannate plant extract is a powerful antifungal agent(333)(334) by destroying candida selectively without harming the good flora in the body(335). It is said that tannate plant extract is effective in treating bacteria, viruses, fungal infections due to its antifungal(333)(334), anti-inflammatory properties(336).


10. Biotin
Biotin or vitamin B7, a coenzyme in the metabolism of fatty acids and leucine, plays an important role in gluconeogenesis(337). According to Università degli Studi di Torino, patients with biotin deficiency are at high risk of candida albicans overgrowth(338).

Biotin prevents yeast to change into its fungal form(339), thus reducing the risk of candida albicans overgrowth.


11. Probiotics (friendly bacteria)
Probiotic is live microorganisms which benefit the host. Intake of probiotics enhances the production of hydrogen peroxide(340) that plays an important role in preventing candida overgrowth and through self-multiple mechanisms(341).


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Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
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(6) Structural analysis of phospho-D-mannan-protein complexes isolated from yeast and mold form cells of Candida albicans NIH A-207 serotype A strain by Shibata N1, Fukasawa S, Kobayashi H, Tojo M, Yonezu T, Ambo A, Ohkubo Y, Suzuki S.(PubMed)
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(311) Streptomyces sp. JS520 produces exceptionally high quantities of undecylprodigiosin with antibacterial, antioxidative, and UV-protective propertiesby Stankovic N1, Radulovic V, Petkovic M, Vuckovic I, Jadranin M, Vasiljevic B, Nikodinovic-Runic J.(PubMed)
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(320) Applications of the phytomedicine Echinacea purpurea (Purple Coneflower) in infectious diseases. by Hudson JB1.(PubMed)
(321) Anethole, a potential antimicrobial synergist, converts a fungistatic dodecanol to a fungicidal agentby Fujita K1, Fujita T, Kubo I.(PubMed)
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(323) Enterococci from piglets--probiotic properties and responsiveness to natural antibacterial substances by Strompfová V1, Lauková A.(PubMed)
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(337) The effect of oxalate on gluconeogenesis by isolated chicken hepatocytes. Increased sensitivity to inhibition as a result of biotindeficiency by Bannister DW, O'Neill IE.(PubMed)
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(339) Candida Infestation and BiotinWritten by Sean Brookwood Published on September 22, 2013
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(341) Candida Diets: Part II: Hydrogen Peroxide Written by Jeff McCombs(342) Glutamine supplementation for young infants with severe gastrointestinal disease. by Brown JV1, Moe-Byrne T, McGuire W.(PubMed)

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