Posted by Chantel Martiromo. research contributed by PubMed
In the study to evaluate whether phytoestrogen intake is associated with reduced breast cancer risk, using a novel phytoestrogen database, posted in PubMed,
showed that among all women, lignan intake was associated with a
reduced breast cancer risk (Q5 vs. Q1 MVOR: 0.81, 95% CI: 0.65, 0.99);
however, following stratification by BMI, this reduction in risk was
statistically significant only among overweight (BMI > 25) women.
Total phytoestrogen intake was also associated with a risk reduction
among overweight women only. Among pre-menopausal women, total
phytoestrogen intake was associated with a significant reduction in
breast cancer risk among overweight women only (Q5 vs. Q1 MVOR: 0.51,
95% CI: 0.30, 0.87). Among post-menopausal women, no statistically
significant association was observed between breast cancer risk and
isoflavones or lignans.
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