Effects of an isoflavone-free soy diet on ovarian hormones in premenopausal women

 Posted by Chantel M. Contributed by US National Library of Medicine National Institutes of Health

In the study to determine the effects of a soy diet containing minimum amounts of isoflavones on circulating levels of ovarian hormones and gonadotropins, nine healthy, regularly cycling women consumed a constant soya-containing diet on a metabolic unit starting on day 2 of a menstrual cycle until day 2 of the next cycle, posted in US National Library of Medicine National Institutes of Health, suggest that at least under the conditions of this study, a soy diet with low levels of isoflavones and low energy intake from protein can reduce circulating ovarian steroids without altering gonadotropins. Our results are consistent with previous studies showing decreased ovarian hormone levels and decreased risk of breast cancer in populations consuming soya diets and an inverse relationship between animal protein intake and breast cancer risk and, therefore, may have implications for breast cancer prevention.

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