Posted by Chantel M. Contributed by US National
Library of Medicine National Institutes of Health
In the study to evaluate soy
intake and serum concentrations of estradiol and isoflavonoids and their
relationship to bone mineral density (BMD) and serum bone-specific
alkaline phosphatase (bone ALP) activity in a cross-sectional study of 87 postmenopausal Japanese women, posted in US National Library of Medicine National Institutes of Health, indicated that soy product and
isoflavone intake and serum isoflavones were not significantly
correlated with BMD after controlling for the covariates. Serum ALP was
not significantly correlated with soy
product and isoflavone intake, the E2/SHBG ratio or serum isoflavones.
The present study supports the association of BMD with serum estradiol;
however, it does not support the association of BMD with soy or isoflavone intake or serum isoflavone levels.
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