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Wednesday, January 23, 2013

Soy product intake and serum isoflavonoid and estradiol concentrations in relation to bone mineral density

  Posted by Chantel M. Contributed by US National Library of Medicine National Institutes of Health

In the study to evaluate soy intake and serum concentrations of estradiol and isoflavonoids and their relationship to bone mineral density (BMD) and serum bone-specific alkaline phosphatase (bone ALP) activity in a cross-sectional study of 87 postmenopausal Japanese women, posted in US National Library of Medicine National Institutes of Health, indicated that soy product and isoflavone intake and serum isoflavones were not significantly correlated with BMD after controlling for the covariates. Serum ALP was not significantly correlated with soy product and isoflavone intake, the E2/SHBG ratio or serum isoflavones. The present study supports the association of BMD with serum estradiol; however, it does not support the association of BMD with soy or isoflavone intake or serum isoflavone levels.

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