Posted by Chantel M. research contributed by US National Library of Medicine
National Institutes of Health
SC-1,
the aqueous phase of soybean fermentation products by bacteria
(Bacillus subtilis and Bacillus brevis), significantly inhibited the
growth and clonogenesity of human hepatocellular (Hep 3B), mouse
hepatocellular (ML-1), and human colorectal (HCT 116 and HT-29)
carcinoma cells. Cytotoxicity of SC-1 in Hep 3B cells was through the
process of apoptosis characterizing by increase in cell population of
sub-G(1) phase, fragmentation of DNA, and change of nuclear morphology,
according to the study by Department of Nursing, Chang Jung Christian
University posted in PubMed,
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